Abstract：
:The incidence of hip fractures in Oslo has shown a secular increase during the past decades. The main aims of the present study were to report the current incidence of hip fractures in Oslo and to determine whether there is a seasonal variation in the occurrence of fractures. Using the electronic diagnosis registers and the lists of the operating theater for the hospitals in Oslo with somatic care, all patients with ICD-9 code 820.X (hip fracture) from May 1, 1996 to April 30, 1997 were identified. Medical records for all identified patients were obtained and diagnosis was verified. Using the population of Oslo on January 1, 1997 as the population at risk, the age- and gender-specific annual incidence rates were calculated. These rates were compared with those for 1988/89 and 1978/79. Outdoor temperature data for Oslo were obtained to study the relation between temperature and number of hip fractures. A total number of 1316 hip fractures was included, of which 78% occurred in women. An exponential increase in incidence with age was observed in both genders. The age-adjusted fracture rates per 10,000 for the age group > or =50 years were 118.0 and 44.0 in 1996/97, 124.3 and 44.9 in 1988/89, and 104.5 and 35.8 in 1978/79 for women and men, respectively. There was no significant seasonal variation in the incidence of hip fractures and no correlation between mean outdoor temperature and number of fractures for each month in 1996/97. The data show that the incidence of hip fractures in Oslo has not changed significantly during the last decade, and it is still the highest reported. The cold climate of Oslo does not seem to contribute to the high incidence.
journal_name
Bonejournal_title
Boneauthors
Lofthus CM,Osnes EK,Falch JA,Kaastad TS,Kristiansen IS,Nordsletten L,Stensvold I,Meyer HEdoi
10.1016/s8756-3282(01)00603-2subject
Has Abstractpub_date
2001-11-01 00:00:00pages
413-8issue
5eissn
8756-3282issn
1873-2763pii
S8756-3282(01)00603-2journal_volume
29pub_type
杂志文章相关文献
BONE文献大全abstract：:Oral bisphosphonates are established therapeutics for postmenopausal osteoporosis. Alternative, simplified dosing regimens that improve tolerability and promote convenience may be advantageous. Ibandronate is a highly potent, nitrogen-containing bisphosphonate that can be administered as a convenient intravenous (i.v....
journal_title：Bone
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.bone.2004.01.007
更新日期：2004-05-01 00:00:00
abstract：:Osteonecrosis of the femoral head (ONFH) is a skeletal disorder characterized by ischemic deterioration, bone marrow edema and eventually femoral head collapse. The systemic regulation of ONFH in adult patients has not been examined. Serum proteomic is an innovative tool that potentially detects simultaneous expressio...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2008.04.019
更新日期：2008-09-01 00:00:00
abstract：:The potential of whole body vibration (WBV) to maintain or enhance musculoskeletal strength during ageing is of increasing interest, with both low and high magnitude WBV having been shown to maintain or increase bone mineral density (BMD) at the lumbar spine and femoral neck. The aim of this study was to determine how...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2020.115802
更新日期：2021-03-01 00:00:00
abstract：:One of the side effects associated with glucocorticoid therapy is glucocorticoid-induced bone loss. Glucocorticoids partly detain bone formation via the inhibition of osteoblastic function, however, the exact mechanism of this inhibition remains elusive. In this study, we examined the effect of dexamethasone, an activ...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2011.01.017
更新日期：2011-05-01 00:00:00
abstract：:Mammalian bone sialoprotein (BSP) is a mineralized tissue-specific protein containing an RGD (arginine-glycine-aspartic acid) cell-attachment sequence and two distinct glutamic acid (glu)-rich regions, with each containing one contiguous glu sequence. These regions have been proposed to contribute to the attachment of...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/s8756-3282(00)00392-6
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:Specific physical loading leads to enhanced bone development during childhood. A general physical activity program mimicking a real-life situation was successful at increasing general physical health in children. Yet, it is not clear whether it can equally increase bone mineral mass. We performed a cluster-r...
journal_title：Bone
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bone.2010.11.018
更新日期：2011-04-01 00:00:00
abstract：:Solute transport in the lacunar-canalicular system (LCS) is essential for bone metabolism and mechanotransduction. Using the technique of fluorescence recovery after photobleaching (FRAP) we have been quantifying solute transport in the LCS of murine long bone as a function of loading parameters and molecular size. Ho...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2009.06.026
更新日期：2009-10-01 00:00:00
abstract：:The effect of homologous recombinant porcine growth hormone (r-pGH) on secondary fracture healing was investigated in a diaphyseal defect of the tibia in Yucatan micropigs. A 1 cm defect of the tibia was created surgically and stabilized with an AO 3.5 mm DCP plate. The treatment group (12 animals) received 100 microg...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/s8756-3282(01)00587-7
更新日期：2001-10-01 00:00:00
abstract：:The Euler number and the connectivity of an arbitrary object is defined, and it is illustrated why the connectivity of an n-dimensional object cannot be estimated in an (n-1)-dimensional section. The disector--principle for 3-D counting of the Euler--events is illustrated in cancellous bone. The correct handling for u...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(93)90144-y
更新日期：1993-05-01 00:00:00
abstract：:Popular psychotropic drugs, like the antidepressant selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), and the mood stabilizer lithium, may have skeletal effects. In particular, preclinical observations suggest a direct negative effect of SSRIs on the skeleton. A potential caveat in ...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2009.12.031
更新日期：2010-04-01 00:00:00
abstract：:Bisphosphonates play an important role in the treatment of metabolic bone diseases such as osteoporosis. In addition to their anti-resorptive activity by triggering osteoclast apoptosis, nitrogen-containing bisphosphonates (N-BP) may also influence osteogenic differentiation, which might rely on their capacity to inhi...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2018.03.020
更新日期：2018-06-01 00:00:00
abstract：:The conventional stereologic procedure for estimating bone surface densities in iliac crest biopsies gives biased estimates because bone substructure is anisotropic and the sectioning of the biopsies is intended to be parallel to the cylindrical axis of the iliac crest biopsy. It has recently been shown that random an...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(87)90126-8
更新日期：1987-01-01 00:00:00
abstract：INTRODUCTION:Parathyroid hormone (PTH) is a key regulator of calcium metabolism. Parathyroid hormone-like hormone (PTHrP) contributes to skeletal development through regulation of chondrocyte proliferation and differentiation during early bone growth. Both PTH and PTHrP act through the same receptor (PTHR1). A second r...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2007.12.005
更新日期：2008-04-01 00:00:00
abstract：INTRODUCTION AND HYPOTHESIS:Diagnosis of prevalent osteoporotic vertebral fracture is complicated by normal or developmental variation in vertebral shape or size and non-osteoporotic deformities that appear to have 'reduced' height. Using our visual approach, the algorithm-based qualitative method (ABQ) a vertebra with...
journal_title：Bone
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.bone.2007.03.015
更新日期：2007-07-01 00:00:00
abstract：:To elucidate the histological events that follow administration of eldecalcitol, a second-generation of vitamin D analog currently awaiting approval as a drug for treatment of osteoporosis, we employed the ovariectomy (OVX) rat model. OVX rats received vehicle or 30ng/kg of eldecalcitol, and sham-operated animals rece...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2011.05.022
更新日期：2011-09-01 00:00:00
abstract：:Heterotopic ossification (HO) involves formation of endochondral bone at non-skeletal sites, is prevalent in severely wounded service members, and causes significant complications and delayed rehabilitation. As common prophylactic treatments such as anti-inflammatory drugs and irradiation cannot be used after multi-sy...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2016.06.014
更新日期：2016-09-01 00:00:00
abstract：:To assess the affect of mild diabetes on calcium metabolism in an animal model, we evaluated calcium homeostasis before pregnancy and during gestation and lactation in non-insulindependent (NIDD) diabetic rat mothers and their neonates (NeoDM). Plasma glucose, calcium (Ca), magnesium (Mg), phosphate (Pi), and immunore...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(87)90124-4
更新日期：1987-01-01 00:00:00
abstract：CASE REPORT:A female patient with consanguineous parents presented with severe symptomatic hypocalcemia (1.62mmol/l) at the age of 4 months. Treatment with oral 1,25-(OH)2-vitamin D and calcium carbonate was started and serum calcium concentrations were stabilized at the lower end of the normal range. Subsequently she ...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2012.06.009
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:There is evidence that the extent of vertebral bone marrow adiposity increases caudally along the vertebral column in children and adolescents. However, no studies have examined the lipid composition of bone marrow along the vertebral column, which may uniquely influence bone acquisition and metabolism durin...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2020.115702
更新日期：2021-01-01 00:00:00
abstract：:The formation of cartilage prior to bone in an endochondral bone formation process suggests that some osteogenic factors exist in the cartilage. This osteogenic activity of cartilage or cartilage cells was examined by implanting ribs and costal cartilage zone into a subcutaneous pocket of abdominal wall, or the growth...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(92)90455-6
更新日期：1992-01-01 00:00:00
abstract：:Despite the potential biological importance of sympathetic activity in human bone metabolism, its effects on bone microarchitecture, a key determinant of bone quality, has not been thoroughly studied. In the present study, we investigated the lumbar spine trabecular bone score (TBS) as an indicator of skeletal deterio...
journal_title：Bone
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.bone.2018.06.023
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:The treatment of complex bone loss scenarios remains challenging. This study evaluates the efficacy of ex vivo regional gene therapy using transduced human adipose-derived stem cells (ASCs) overexpressing bone morphogenetic protein-2 (BMP-2) to treat critical-sized bone defects. METHODS:Critical-sized femor...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2020.115524
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Avoidant Restrictive Food Intake Disorder (ARFID) and Anorexia Nervosa (AN) cause significant underweight in children and young people (CYP). The association of low bone mineral density (BMD) and underweight CYP in AN is well established, but less is known about BMD in ARFID. METHODS:Retrospective case-note...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2020.115307
更新日期：2020-05-01 00:00:00
abstract：:G protein-coupled receptors (GPCRs) require G proteins for intracellular signaling to regulate a variety of growth and maintenance processes, including osteogenesis and bone turnover. Bone maintenance events may be altered by changes in the activity or level of G proteins, which then modify signaling in bone cells suc...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2013.11.021
更新日期：2014-02-01 00:00:00
abstract：:In order to investigate the effect of fluoride on bone mineral crystals, we gave groups of female rats 8 mM NaF/L water and distilled water to control groups. The rats were sacrificed at six weeks, three months, and six months. The fluor content of the bone was determined by neutron activation. X-ray diffraction showe...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(92)90085-b
更新日期：1992-01-01 00:00:00
abstract：:We performed a comprehensive analysis of the relationships between histologic indices in the iliac crest (cancellous bone volume, trabecular structural indices, cortical width, and core width) and bone density in the spine, hip, and wrist in 81 patients with various metabolic bone diseases including osteoporosis, oste...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(92)90203-9
更新日期：1992-01-01 00:00:00
abstract：:The Wnt/β-catenin signaling pathway plays an essential role in osteoblast biology. Sclerostin is a soluble antagonist of Wnt/β-catenin signaling secreted primarily by osteocytes. Current evidence indicates that sclerostin likely functions as a local/paracrine regulator of bone metabolism rather than as an endocrine ho...
journal_title：Bone
pub_type： 杂志文章,评审
doi：10.1016/j.bone.2016.12.004
更新日期：2017-03-01 00:00:00
abstract：:Tankyrase is a poly (ADP-ribose) polymerase that leads to ubiquitination and degradation of target proteins. Since tankyrase inhibitors suppress the degradation of AXIN protein, a negative regulator of the canonical Wnt pathway, they effectively act as Wnt inhibitors. Small molecule tankyrase inhibitors are being inve...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/j.bone.2017.10.017
更新日期：2018-01-01 00:00:00
abstract：:Bone mineral density is under strong genetic control and polymorphisms of the vitamin D receptor (VDR) have been suggested to account for some of the genetic variation in bone mass. However, the relationship between VDR polymorphisms and bone density is controversial and has not been confirmed by all workers. Since th...
journal_title：Bone
pub_type： 杂志文章
doi：10.1016/8756-3282(95)00483-1
更新日期：1996-03-01 00:00:00
abstract：:General dental practitioners use a vast amount of panoramic radiography in their routine clinical work, but valuable information about patients' osteoporotic status is not collected. There are many reasons for this, but one of the prime reasons must be the disruption involved in clinical routine with lengthy manual ra...
journal_title：Bone
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bone.2006.10.024
更新日期：2007-04-01 00:00:00
