Carob pulp preparation for treatment of hypercholesterolemia.

abstract：:Dyspnea is the most common symptom experienced by patients with chronic obstructive pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary lifestyle which predictably leads to extensive skeletal muscle deconditioning, social isolation, and its negative psychological sequalae. This "dysp...

journal_title：Advances in therapy

authors： O'Donnell DE,Milne KM,James MD,de Torres JP,Neder JA

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:This study aims to evaluate the early predictive value for postoperative sepsis and 30-day mortality in liver transplant patients using sequential organ failure assessment (SOFA). METHODS:A total of 96 liver transplant patients were enrolled into this study from February 2015 to June 2018. The general inf...

journal_title：Advances in therapy

authors： Wang XW,Niu XG,Li JX,Zhang SS,Jiao XF

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and has been associated with cardiovascular disease, the leading cause of mortality in diabetes. As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in p...

journal_title：Advances in therapy

authors： Baltzis D,Roustit M,Grammatikopoulou MG,Katsaboukas D,Athanasiou V,Iakovou I,Veves A,Manes C,Trakatelli MC

更新日期：2016-10-01 00:00:00

abstract：:In an open, uncontrolled study, 105 patients with locomotor system symptoms were treated twice daily with an ointment containing a Symphytum active substance complex. A clear therapeutic effect was noted on chronic and subacute symptoms that were accompanied mainly by functional disturbances and pain in the musculatur...

journal_title：Advances in therapy

authors： Kucera M,Kálal J,Polesná Z

更新日期：2000-07-01 00:00:00

abstract：:Venous leg ulcers (VLUs) are the most severe manifestation of chronic venous disease (CVD). Due to their chronic nature, high recurrence rate and slow healing time, VLUs account for 80% of all leg ulcers seen in patients with CVD. VLUs impose a heavy burden on patients that reduces their quality of life; VLUs also rep...

journal_title：Advances in therapy

authors： Nicolaides AN

更新日期：2020-02-01 00:00:00

abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

journal_title：Advances in therapy

authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

更新日期：2020-12-14 00:00:00

abstract：INTRODUCTION:This retrospective study used data from a primary care database to compare two insulin products in routine clinical practice for the treatment of type 2 diabetes in the UK. PATIENTS AND METHODS:Records were analyzed for patients with type 2 diabetes who had been initiated on biphasic insulin aspart 30 (BI...

journal_title：Advances in therapy

authors： Fakhoury WK,Richter H,Christensen TE

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Despite improved understanding of the risks of influenza and better vaccines for older patients, influenza vaccination rates remain subpar, including in high-risk groups such as older adults, and demonstrate significant racial and ethnic disparities. METHODS:This study considers demographic, clinical, and...

journal_title：Advances in therapy

authors： Hall LL,Xu L,Mahmud SM,Puckrein GA,Thommes EW,Chit A

更新日期：2020-05-01 00:00:00

abstract：:Hypertension is recognized as a major risk factor for cardiovascular and renal diseases and represents the leading cause of mortality worldwide. In spite of proven benefits of hypertension treatment, blood pressure control rates are poor, even in high-income countries with virtually full-access to therapies. Nearly 75...

journal_title：Advances in therapy

authors： Gorostidi M,de la Sierra A

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. METHODS:In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled...

journal_title：Advances in therapy

authors： Petrov A,Perekhvatova N,Skulachev M,Stein L,Ousler G

更新日期：2016-01-01 00:00:00

abstract：:The article "Sleep Quality and Congestion with Breathe Right Nasal Strips: Two Randomized Controlled Trials", written by Michael J. Noss, Renee Ciesla, and Gilbert Shanga, was originally published electronically on the publisher's internet portal (currently SpringerLink) on June 17, 2019 without Open Access. The artic...

journal_title：Advances in therapy

authors： Noss MJ,Ciesla R,Shanga G

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:To determine patient and rheumatologist preferences for rheumatoid arthritis (RA) treatment attributes in Spain and to evaluate their attitude towards shared decision-making (SDM). METHODS:Observational, descriptive, exploratory and cross-sectional study based on a discrete choice experiment (DCE). To ide...

journal_title：Advances in therapy

authors： Díaz-Torné C,Urruticoechea-Arana A,Ivorra-Cortés J,Díaz S,Dilla T,Sacristán JA,Inciarte-Mundo J,Comellas M,Prades M,Lizán L

更新日期：2020-04-01 00:00:00

abstract：:Fibroids, the most common tumor in women of reproductive age, impact negatively on women's health and quality of life, and have significant cost implications for their management. The current mainstay treatments are surgical (myomectomy and hysterectomy) and more recently radiological (UAE and focused ultrasound surge...

journal_title：Advances in therapy

authors： Talaulikar VS,Manyonda IT

更新日期：2012-08-01 00:00:00

abstract：:Many doubts surround the numerous forms of nonsurgical treatment of nonresectable hepatocellular carcinoma (HCC). Our study aimed to reach reliable conclusions on the actual efficacy of these treatments. We examined 85 studies involving a total of 6746 patients: 6113 were treated; the remaining 633 were not. We applie...

journal_title：Advances in therapy

authors： Malaguarnera M,Trovato G,Restuccia S,Giugno I,Franzé CM,Receputo G,Siciliano R,Motta M,Trovato BA

更新日期：1994-11-01 00:00:00

abstract：:Angio-immunoblastic T-cell lymphoma (AITL), a rare disease that constitutes 1% to 2% of non-Hodgkin's lymphomas, presents in middle-aged and elderly individuals. This report describes a patient with high-grade fever and lymphadenopathy. An extensive in-hospital work-up that included lymph node biopsy yielded negative ...

journal_title：Advances in therapy

authors： Usmani SZ,Sahay T,Eisenberg L

更新日期：2007-07-01 00:00:00

abstract：:Subretinal hemorrhage secondary to age-related macular degeneration (AMD) has a poor visual prognosis. Surgical drainage of the blood improves visual acuity only in selected patients. We report on two elderly patients with spontaneous subretinal hemorrhage from AMD. In one eye, recombinant tissue plasminogen activator...

journal_title：Advances in therapy

authors： Hesse L,Kroll P

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:To evaluate the impact on cost, time, resource use, and clinic workflow of converting the route of drug administration from a neurokinin-1 receptor antagonist (NK-1 RA) 30-min intravenous (IV) infusion to aprepitant IV, and more specifically to IV push, within a multicenter community oncology practice. METHODS...

journal_title：Advances in therapy

authors： Burns D,Kula J,Marshall S,Ashworth E,Ornelas M

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Extraintestinal manifestations (EIMs) in patients with Crohn's disease (CD) are common and associated with additional morbidity. This study aimed to evaluate the effect of adalimumab therapy on EIM resolution and identify potential predictors of EIM resolution in adult and pediatric patients with moderate ...

journal_title：Advances in therapy

authors： Louis EJ,Reinisch W,Schwartz DA,Löfberg R,Robinson AM,Berg S,Wang AW,Maa JF,Huang B,Pappalardo B

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Naproxen is an NSAID with documented efficacy in pain management; however, it is associated with serious dose-related adverse events. A lower-dose naproxen drug product with comparable efficacy to commercially available naproxen could address these concerns. We studied the efficacy and safety of naproxen sub...

journal_title：Advances in therapy

authors： Young CL,Strand V,Altman R,Daniels S

更新日期：2013-10-01 00:00:00

abstract：:Life expectancy has increased substantially over the last few decades, leading to a worldwide increase in the prevalence and burden of aging-associated diseases. Recent evidence has proven that cellular senescence contributes substantially to the development of these disorders. Cellular senescence is a state of cell c...

journal_title：Advances in therapy

authors： Amaya-Montoya M,Pérez-Londoño A,Guatibonza-García V,Vargas-Villanueva A,Mendivil CO

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to determine prescribing trends in a specialist glaucoma clinic in the UK. Specifically, the aims were to determine which drugs were prescribed as first-, second-, and third-line treatment, the persistence of first-, second-, and third-line treatment regimens, and the proporti...

journal_title：Advances in therapy

authors： Fajgenbaum M,Ansari E

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Repository corticotropin injection (RCI; H.P. Acthar® Gel; Mallinckrodt Pharmaceuticals Inc., Hampton, NJ) is a highly purified, prolonged-release porcine preparation of adrenocorticotropic hormone (ACTH) analogue that is FDA-approved for treatment of 19 autoimmune and inflammatory disorders. The diverse p...

journal_title：Advances in therapy

authors： Philbin M,Niewoehner J,Wan GJ

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Healthy eating is a critical aspect of the prevention and management of type 2 diabetes (T2DM). Disrupted eating patterns can result in poor glucose control and increase the likelihood of diabetic complications. Teneligliptin inhibits dipeptidyl peptidase-4 activity for 24 h and suppresses postprandial hyp...

journal_title：Advances in therapy

authors： Kadowaki T,Haneda M,Ito H,Sasaki K,Hiraide S,Matsukawa M,Ueno M

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Asthma is associated with significant economic burden. Inhaled corticosteroid and long-acting beta2-agonist (ICS/LABA) combination therapies are considered mainstays of treatment. We describe real-world use of ICS/LABAs by comparing treatment persistence and adherence among patients with asthma in the Unit...

journal_title：Advances in therapy

authors： Parimi M,Svedsater H,Ann Q,Gokhale M,Gray CM,Hinds D,Nixon M,Boxall N

更新日期：2020-06-01 00:00:00

abstract：:As head and neck squamous cell carcinoma (HNSCC) patients with distant metastases (DM) were generally treated only palliatively, the value of screening for DM was usually limited to attempts to avoid extensive locoregional treatment when DM were present pretreatment. Recently, the concept of treating oligometastases, ...

journal_title：Advances in therapy

authors： de Bree R,Senft A,Coca-Pelaz A,Kowalski L,Lopez F,Mendenhall W,Quer M,Rinaldo A,Shaha AR,Strojan P,Takes RP,Silver CE,Leemans CR,Ferlito A

更新日期：2018-02-01 00:00:00

abstract：:Bacterial translocation is the passage of bacteria or endotoxins from the gastrointestinal tract to extraintestinal sites, such as mesenteric lymph nodes, liver, spleen, and bloodstream. In this study, the investigators examined the effects of various enteral nutrients on bacterial translocation and intestinal morphol...

journal_title：Advances in therapy

authors： Aydogan A,Kismet K,Kilicoglu B,Erel S,Ozcan AH,Gollu A,Yildiz E,Akkus MA

更新日期：2007-01-01 00:00:00

abstract：:Hyperthyroidism is associated with increased bone turnover. Besides the hormones of calcium metabolism, locally produced factors are important in maintaining normal bone metabolism. Interleukin-6 (IL-6), in particular, has a major influence on bone turnover. In this study, serum IL-6 and tumor necrosis factor-alpha (T...

journal_title：Advances in therapy

authors： Sekeroglu MR,Altun ZB,Algün E,Dülger H,Noyan T,Balaharoglu R,Oztürk M

更新日期：2006-05-01 00:00:00

abstract：INTRODUCTION:Phase IV post-marketing surveillance studies are needed to evaluate the real-world safety and effectiveness of drug products. This study aimed to evaluate the safety and effectiveness of biosimilar etanercept (Altebrel, AryoGen Co., Iran) in patients with rheumatoid arthritis (RA), ankylosing spondylitis (...

journal_title：Advances in therapy

authors： Gharibdoost F,Salari AH,Salesi M,Ebrahimi Chaharom F,Mottaghi P,Hosseini M,Sahebari M,Nazarinia M,Mirfeizi Z,Shakibi M,Moussavi H,Karimifar M,Mowla K,Karimzadeh H,Anjidani N,Jamshidi A

更新日期：2021-01-11 00:00:00

abstract：:The prevalence of chronic airways diseases such as chronic obstructive pulmonary disease and asthma is increasing. They lead to symptoms such as a cough and shortness of breath, partially through bronchoconstriction. Inhaled anticholinergics are one of a number of treatments designed to treat bronchoconstriction in ai...

journal_title：Advances in therapy

authors： Flynn RA,Glynn DA,Kennedy MP

更新日期：2009-10-01 00:00:00

abstract：:Chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal (GI) disorders. Current treatment options, either prescription or nonprescription medications, have limited efficacy in a subset of patients. There is significant demand for more efficacious medications for the...

journal_title：Advances in therapy

authors： Vazquez-Roque MI,Bouras EP

更新日期：2013-03-01 00:00:00