Abstract:
:From our experiments combining in vivo calcium imaging and electrophysiology on fly vertical motion-sensitive cells (VS-cells) during visual stimulation, we infer different mechanisms of calcium entry within different dendritic compartments; while in the main dendritic branches calcium influx from extracellular space takes place only via voltage-activated calcium channels (VACCs), calcium enters the dendritic tips through VACCs as well as nicotinic acetylcholine receptors (nAChRs). Consequently, neuronal nACHRs of insects have to be assumed to be permeable to some extent for calcium under in vivo conditions.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Single S,Borst Adoi
10.1152/jn.00215.2001subject
Has Abstractpub_date
2002-03-01 00:00:00pages
1616-24issue
3eissn
0022-3077issn
1522-1598journal_volume
87pub_type
杂志文章abstract::Animal studies have suggested that tissue injury-related increased levels of glutamate may be involved in peripheral nociceptive mechanisms in deep craniofacial tissues. Indeed, injection of glutamate (0.1-1 M, 10 microl) into the temporomandibular region evokes reflex jaw muscle responses through activation of periph...
journal_title:Journal of neurophysiology
pub_type: 临床试验,杂志文章
doi:10.1152/jn.2001.86.2.782
更新日期:2001-08-01 00:00:00
abstract::Neocortical circuits exhibit a rich dynamic repertoire, and their ability to achieve entrainment (adjustment of their frequency to match the input frequency) is thought to support many cognitive functions and indicate functional flexibility. Although previous studies have explored the influence of various circuit prop...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00401.2019
更新日期:2020-03-01 00:00:00
abstract::Granule cells and parallel fiber circuits in the dorsal cochlear nucleus (DCN) play a role in integration of multimodal sensory with auditory inputs. The activity of granule cells is regulated through inhibitory connections made by Golgi cells. Golgi cells in turn probably receive parallel fiber inputs and regulate ac...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00396.2006
更新日期:2006-11-01 00:00:00
abstract::When they are 1-2 mo old, domesticated Mongolian gerbils begin having initially mild seizures which become more severe with age. To evaluate the development of this increasing seizure severity, we obtained field potential responses of the dentate gyrus to paired-pulse stimulation of the perforant path during seizures....
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2002.88.2.783
更新日期:2002-08-01 00:00:00
abstract::The relation between impedance change and the location and magnitude of a tonic synaptic conductance was examined in compartmental motoneuron models based on previously published data. The dependency of motoneuron impedance on system time constant (tau), electrotonic length (L), and dendritic-to-somatic conductance ra...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00873.2003
更新日期:2004-09-01 00:00:00
abstract::The structural features of a synaptic connection between central neurons play an important role in determining the strength of the connection. In the present study, we have examined the relationship between the structural and functional properties of glycinergic synapses in the rat spinal cord. We have analyzed the st...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.82.1.312
更新日期:1999-07-01 00:00:00
abstract::1. Mechanosensory hairs on the surface of the crayfish telson are dually innervated, one sensory cell responding to headward, the other to tailward deflection of the hair. The average conduction velocity of headward elements was 0.8 m/s (variance 0.08) and of tailward elements 1.2 m/s (variance 0.19). In a frequency r...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1976.39.4.816
更新日期:1976-07-01 00:00:00
abstract::The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00796.2014
更新日期:2015-11-01 00:00:00
abstract::The R6/2 mouse is the most frequently used model for experimental and preclinical drug trials in Huntington's disease (HD). When the R6/2 mouse was first developed, it carried exon 1 of the huntingtin gene with ~150 cytosine-adenine-guanine (CAG) repeats. The model presented with a rapid and aggressive phenotype that ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00762.2011
更新日期:2012-01-01 00:00:00
abstract::Nonsynaptic mechanisms exert a powerful influence on seizure threshold. It is well-established that nonsynaptic epileptiform activity can be induced in hippocampal slices by reducing extracellular Ca(2+) concentration. We show here that nonsynaptic epileptiform activity can be readily induced in vitro in normal (2 mM)...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00196.2001
更新日期:2002-01-01 00:00:00
abstract::Previous studies have revealed a new form of activity-dependent modulation of the afterhyperpolarization (AHP) in tactile (T) neurons of the leech Hirudo medicinalis. The firing of T cells is characterized by an AHP, which is mainly due to the activity of the Na+/K+ ATPase. Low-frequency repetitive stimulation of T ne...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00075.2005
更新日期:2005-08-01 00:00:00
abstract::The operculoinsular cortical region has a major role in the representation of noxious stimuli, based on functional imaging observations, clinical lesion studies, and EEG recordings of specifically pain-related laser-evoked potentials (LEPs) in humans. The source of LEPs has not been identified, and several somatic rep...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00512.2006
更新日期:2006-11-01 00:00:00
abstract::The spinal network coordinating locomotion is comprised of a core of glutamate and glycine interneurons. This network is modulated by several transmitter systems including spinal GABA interneurons. The purpose of this study is to explore the contribution of GABAergic neurons to the regulation of locomotor burst freque...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00233.2004
更新日期:2004-10-01 00:00:00
abstract::Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00555.2014
更新日期:2015-03-15 00:00:00
abstract::Operant conditioning was used to train cats with their heads immobilized to localize sound by directing their eyes to the location of the sources. The kinematics of those eye movements were studied and compared with eye movements to visual targets at the same locations. The main finding of this study is that eye movem...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.82.2.955
更新日期:1999-08-01 00:00:00
abstract::1. We examined the role of gamma-aminobutyric acid (GABA)-mediated inhibition in shaping excitatory tuning curves and creating selectivity for frequency-modulated (FM) sweeps in 29 neurons in the central nucleus of the inferior colliculus (ICC) of the pallid bat, with the use of single-unit recording coupled with the ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.76.2.1059
更新日期:1996-08-01 00:00:00
abstract::1. Spatiotemporal receptive fields (RFs) for left and right eyes were studied for simple cells in the cat's striate cortex to examine the idea that stereoscopic depth information is encoded via structural differences of RFs between the two eyes. Traditional models are based on neurons that possess matched RF profiles ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.75.5.1779
更新日期:1996-05-01 00:00:00
abstract::1. Patterns of respiratory neuronal activity were examined in pentobarbitone anesthetized adult cats in a circumscribed area of the ventrolateral medulla, which has previously been defined as the pre-Bötzinger complex (pre-BOTC) from electrophysiological and morphological criteria in the brain stem-spinal cord prepara...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1995.73.4.1452
更新日期:1995-04-01 00:00:00
abstract::Three nonspiking interneurons are described in this paper that influence the activity of the motor neurons of three muscles of the proximal leg joints of the stick insect. Interneurons were recorded and stained intracellularly by glass microelectrodes; motor neurons were recorded extracellularly with oil-hook electrod...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1998.79.6.2964
更新日期:1998-06-01 00:00:00
abstract::Glutamatergic inputs clustered over approximately 20-40 microm can elicit local N-methyl-D-aspartate (NMDA) spike/plateau potentials in terminal dendrites of cortical pyramidal neurons, inspiring the notion that a single terminal dendrite can function as a decision-making computational subunit. A typical terminal basa...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00011.2008
更新日期:2008-05-01 00:00:00
abstract::1. The response properties of accessory optic system (AOS) neurons were assessed using single-unit extracellular recording from each of the three AOS terminal nuclei [medial, lateral, and dorsal terminal nuclei (MTN, LTN, and DTN)] in the anesthetized rabbit. 2. AOS neurons had large, monocular (contralateral) recepti...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1988.60.6.2037
更新日期:1988-12-01 00:00:00
abstract::1. We recorded local field potentials in the parafoveal representation in the primary visual cortex of anesthetized and paralyzed macaque monkeys with a multicontact electrode that provided for sampling of neural activity at 16 sites along a vertical penetration. Differential recordings at adjacent contacts were trans...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1994.72.5.2151
更新日期:1994-11-01 00:00:00
abstract::Interhemispheric interactions through the corpus callosum play an important role in the control of bimanual forces. However, the extent to which physiological connections between primary motor cortices are modulated during increasing levels of bimanual force generation in intact humans remains poorly understood. Here ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00876.2015
更新日期:2016-03-01 00:00:00
abstract::Reach-to-grasp movements require information about the distance and size of target objects. Calibration of this information could be achieved via feedback information (visual and/or haptic) regarding terminal accuracy when target objects are grasped. A number of reports suggest that the nervous system alters reach-to-...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00112.2013
更新日期:2013-12-01 00:00:00
abstract::Variations in cortical oscillations in the alpha (7-14 Hz) and beta (15-29 Hz) range have been correlated with attention, working memory, and stimulus detection. The mu rhythm recorded with magnetoencephalography (MEG) is a prominent oscillation generated by Rolandic cortex containing alpha and beta bands. Despite its...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00535.2009
更新日期:2009-12-01 00:00:00
abstract::The pharynx of C. elegans is a rhythmically active muscle that pumps bacteria into the gut of the nematode. This activity is maintained by action potentials, which qualitatively bear a resemblance to vertebrate cardiac action potentials. Here, the ionic basis of the resting membrane potential and pharyngeal action pot...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00233.2001
更新日期:2002-02-01 00:00:00
abstract::For primary auditory cortex (AI) laminae, there is little evidence of functional specificity despite clearly expressed cellular and connectional differences. Natural sounds are dominated by dynamic temporal and spectral modulations and we used these properties to evaluate local functional differences or constancies ac...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00624.2009
更新日期:2010-01-01 00:00:00
abstract::Recent work has investigated the link between motor learning and sensory function in arm movement control. A number of findings are consistent with the idea that motor learning is associated with systematic changes to proprioception (Haith A, Jackson C, Mial R, Vijayakumar S. Adv Neural Inf Process Syst 21: 593-600, 2...
journal_title:Journal of neurophysiology
pub_type: 杂志文章,随机对照试验
doi:10.1152/jn.00122.2012
更新日期:2012-12-01 00:00:00
abstract::It is well recognized that the brain uses sensory information to accurately produce motor commands. Indeed, most research into the relationship between sensory and motor systems has focused on how sensory information modulates motor function. In contrast, recent studies have begun to investigate the reverse: how senso...
journal_title:Journal of neurophysiology
pub_type: 杂志文章,随机对照试验
doi:10.1152/jn.00949.2010
更新日期:2011-05-01 00:00:00
abstract::The countermanding saccade task has been used in many studies to investigate the neural mechanisms that underlie the decision to execute or restrain rapid eye movements. In this task, the presentation of a saccade target is sometimes followed by the appearance of a stop cue that indicates that the subject should cance...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01323.2005
更新日期:2006-10-01 00:00:00