Mechanoreceptors for near-field water displacements in crayfish.


:1. Mechanosensory hairs on the surface of the crayfish telson are dually innervated, one sensory cell responding to headward, the other to tailward deflection of the hair. The average conduction velocity of headward elements was 0.8 m/s (variance 0.08) and of tailward elements 1.2 m/s (variance 0.19). In a frequency range from 0.05 to 200 Hz, thresholds were lowest near 20 Hz: 0.08 mum (pp) for headward-sensitive and 0.1 mum (pp) for tailward-sensitive cells. 2. The receptors are displacement sensitive since thresholds are of the same order of magnitude over the frequency range 1-70 Hz when the hair is moved by a vibrating wire loop. With natural stimuli (surface waves), the velocity component of the particle movement (and consequently force) becomes influential. The coding of a broad range of stimulus intensities is aided by variations in mechanical properties of the hair. 3. Marked directionality (better than 4:1), in addition to the dual innervation, enhances vector detection. At least part of this characteristic stems from the hingelike articulation of the hair on the body surface: the hair can be moved easily 40 degrees tailward and 20 degrees headward, but must be forced in the orthogonal direction. Morphological studies indicate the presence of a double pivoted hinge, with rigid guides for movement of the hair shaft. Preliminary results of electron microscope examination show a clearly polarized arrangement of densely packed microtubules in the two dendrites; they appear interconnected in groups of two and three along a line parallel to the sensitivity plane of the receptor. 4. The 50-fold threshold difference between the results of behavioral experiments in lobsters (24) and the data for the individual receptors reported here may be due to improvement in signal-to-noise ratio by central nervous averaging of the input from an estimated 2 X 10(3) receptors (Procambarus), and/or to the kind of threshold criteria applied to individual receptor thresholds. As would be expected (35), the sensory cells of each directional class synapse with separate interneurons: in this way, the organism might employ differential microphones to reduce background noise. 5. The receptors are analogous to those of the lateral-line system in lower vertebrates in having receptors with sensitivities polarized by 180 degrees. These similarities suggest that in both cases monitoring of near field water displacements has proved in essential way of orienting in opaque waters.


J Neurophysiol


Wiese K




Has Abstract


1976-07-01 00:00:00












  • Respiratory-related neural assemblies in the brain stem midline.

    abstract::1. The initial objective of this study was to determine whether respiratory-related neural assemblies exist in the brain stem midline. A second goal was to seek evidence for concurrent relationships among the neurons that could generate the detected synchrony. 2. Experiments were conducted on anesthetized, paralyzed, ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Lindsey BG,Hernandez YM,Morris KF,Shannon R,Gerstein GL

    更新日期:1992-04-01 00:00:00

  • Interactions of inhibition and excitation in the light-evoked currents of X type retinal ganglion cells.

    abstract::The excitatory and inhibitory conductances driving the light-evoked currents (LECs) of cat and ferret ON- and OFF-center X ganglion cells were examined in sliced and isolated retina preparations using center spot stimulation in tetrodotoxin (TTX)-containing Ringer. ON-center X ganglion cells showed an increase in an e...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Cohen ED

    更新日期:1998-12-01 00:00:00

  • Temporal correlations in sensory-synaptic interactions: example in crayfish stretch receptors.

    abstract::1. The effects of inhibitory postsynaptic potential (IPSP) barrages on coding of sinusoidal length inputs were investigated in slowly and rapidly adapting stretch receptors of crayfish (RM1 and RM2, respectively). To examine the contribution of postsynaptic firings, a description was obtained of the temporal correlati...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Barrio LC,Buño W

    更新日期:1990-06-01 00:00:00

  • Glutamate currents in morphologically identified human dentate granule cells in temporal lobe epilepsy.

    abstract::Glutamate-receptor-mediated synaptic transmission was studied in morphologically identified hippocampal dentate granule cells (DGCs; n = 31) with the use of whole cell patch-clamp recording and intracellular injection of biocytin or Lucifer yellow in slices prepared from surgically removed medial temporal lobe specime...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Isokawa M,Levesque M,Fried I,Engel J Jr

    更新日期:1997-06-01 00:00:00

  • Functional properties of ryanodine receptors in hippocampal neurons change during early differentiation in culture.

    abstract::6-((4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl)amino)hexanoic acid ryanodine (BODIPY-ryanodine) binding and Ca(2+) imaging were used to study the properties of ryanodine receptors (RyRs) and cytoplasmic Ca(2+) (Ca) changes in neurons cultured from the embryonic rat hippocampus during the earli...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Sukhareva M,Smith SV,Maric D,Barker JL

    更新日期:2002-09-01 00:00:00

  • Effect of cerebellar inactivation by lidocaine microdialysis on the vestibuloocular reflex in goldfish.

    abstract::Vestibuloocular reflex performance and adaptation were examined during vestibulocerebellar inactivation by localized lidocaine microdialysis or injection in goldfish. In the light, eye velocity perfectly compensated for head velocity (Vis-VOR) during sinusoidal yaw rotation (1/8 Hz +/- 20 degrees). In the dark, the re...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: McElligott JG,Beeton P,Polk J

    更新日期:1998-03-01 00:00:00

  • Reversible inactivation of monkey superior colliculus. I. Curvature of saccadic trajectory.

    abstract::The neurons in the intermediate layers of the monkey superior colliculus (SC) that discharge before saccadic eye movements can be divided into at least two types, burst and buildup neurons, and the differences in their characteristics are compatible with different functional contributions of the two cell types. It has...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Aizawa H,Wurtz RH

    更新日期:1998-04-01 00:00:00

  • Homocysteine reduces NMDAR desensitization and differentially modulates peak amplitude of NMDAR currents, depending on GluN2 subunit composition.

    abstract::N-methyl-d-aspartate receptors (NMDARs) have been linked to schizophrenia because agents that bind the receptor, like ketamine and phencyclidine, are capable of inducing schizophrenia-like symptoms. Here we show that the amino acid homocysteine (HCY), which is increased in the blood of schizophrenia patients, reduces ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Bolton AD,Phillips MA,Constantine-Paton M

    更新日期:2013-10-01 00:00:00

  • Mechanisms of pattern generation underlying swimming in Tritonia. IV. Gating of central pattern generator.

    abstract::Swimming behavior in the marine mollusc Tritonia diomedea is episodic, consisting of a series of alternating dorsal and ventral flexions initiated by a brief sensory stimulus. The swim motor pattern is generated by a network formed of four groups of premotor interneurons: cerebral cell 2 (C2), dorsal swim interneurons...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Getting PA,Dekin MS

    更新日期:1985-02-01 00:00:00

  • Regulation of N- and L-type Ca2+ channels in adult frog sympathetic ganglion B cells by nerve growth factor in vitro and in vivo.

    abstract::To examine mechanisms responsible for the long-term regulation of Ca2+-channels in an adult neuron, changes in whole cell Ba2+ current (IBa) were examined in adult bullfrog sympathetic ganglion B cells in vitro. Cells were cultured at low density in defined, serum free medium. After 15 days, total IBa was similar to t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Lei S,Dryden WF,Smith PA

    更新日期:1997-12-01 00:00:00

  • Cellular mechanisms of nociception in the frog.

    abstract::Cellular mechanisms underlying defense reactions induced by noxious heat and acids were studied in frogs (Rana pipiens) by measuring whole cell membrane currents in cultured dorsal root ganglion (DRG) neurons. Seventy-eight of 82 DRG neurons exposed to 3-s ramps of increasing temperature to 48 degrees C exhibited an i...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Kuffler DP,Lyfenko A,Vyklický L,Vlachová V

    更新日期:2002-10-01 00:00:00

  • Dynamics of receptive field size in primary visual cortex.

    abstract::Recent studies have shown that the initial responses evoked by a stimulus in neurons of primary visual cortex are dominated by low spatial frequency information in the image, whereas finer spatial scales dominate later in the response. Such phenomena could arise from the dynamics of receptive field (RF) size at early ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Malone BJ,Kumar VR,Ringach DL

    更新日期:2007-01-01 00:00:00

  • Multiple high-threshold calcium currents in acutely isolated rat amygdaloid pyramidal cells.

    abstract::1. High-threshold Ca2+ currents were studied in large pyramidal cells acutely dissociated from the rat amygdaloid complex. L-, N-, and P-type currents were present in about equal proportions in these cells and accounted for most of the whole-cell current. ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Foehring RC,Scroggs RS

    更新日期:1994-01-01 00:00:00

  • Weakly modulated spike trains: significance, precision, and correction for sample size.

    abstract::Many single-unit electrophysiological studies of visual cortex have investigated strong evoked responses to simple stimuli such as oriented gratings. Experiments involving other types of stimuli, such as natural scenes, higher-order features, and surface brightness, produce single-unit responses that are more difficul...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Hung CP,Ramsden BM,Roe AW

    更新日期:2002-05-01 00:00:00

  • Sites of action of segmental and descending control of transmission on pathways mediating PAD of Ia- and Ib-afferent fibers in cat spinal cord.

    abstract::The present series of investigations was aimed to disclose the possible sites of action of excitatory and inhibitory inputs on tho-interneuron pathway mediating the primary afferent depolarization (PAD) of group I afferents of extensor muscles in the cat spinal cord. To this end we compared the effects produced by sti...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Rudomín P,Jiménez I,Solodkin M,Dueñas S

    更新日期:1983-10-01 00:00:00

  • Relationship between color discrimination and neural responses in the inferior temporal cortex of the monkey.

    abstract::Earlier studies suggest that the inferior temporal (IT) cortex of the monkey plays a key role in color discrimination. Here, we examined the quantitative relationship between color judgment in monkeys and the responses of color-selective neurons in the anterior part of the IT cortex (area TE) by comparing neuronal act...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Matsumora T,Koida K,Komatsu H

    更新日期:2008-12-01 00:00:00

  • Lack of effect of mossy fiber-released zinc on granule cell GABA(A) receptors in the pilocarpine model of epilepsy.

    abstract::The recurrent mossy fiber pathway of the dentate gyrus expands dramatically in the epileptic brain and serves as a mechanism for synchronization of granule cell epileptiform activity. It has been suggested that this pathway also promotes epileptiform activity by inhibiting GABA(A) receptor function through release of ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Molnár P,Nadler JV

    更新日期:2001-05-01 00:00:00

  • Simultaneous contribution of two rod pathways to AII amacrine and cone bipolar cell light responses.

    abstract::Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Trexler EB,Li W,Massey SC

    更新日期:2005-03-01 00:00:00

  • Role of cAMP in the short-term modulation of a neuromuscular system in aplysia.

    abstract::Neuromuscular synapses in buccal muscle I3a of Aplysia are modulated by the small cardioactive peptide (SCP), a peptide cotransmitter that is intrinsic to the motor neurons, and by serotonin (5-HT) released from modulatory neurons that are extrinsic to the motor circuit. Although the modulation of excitatory junction ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Fox LE,Lloyd PE

    更新日期:2000-03-01 00:00:00

  • Formal and attribute-specific information in primary visual cortex.

    abstract::We estimate the rates at which neurons in the primary visual cortex (V1) of anesthetized macaque monkeys transmit stimulus-related information in response to three types of visual stimulus. The stimuli-randomly modulated checkerboard patterns, stationary sinusoidal gratings, and drifting sinusoidal gratings-have very ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Reich DS,Mechler F,Victor JD

    更新日期:2001-01-01 00:00:00

  • Maintenance of relational information in working memory leads to suppression of the sensory cortex.

    abstract::Working memory (WM) for sensory-based information about individual objects and their locations appears to involve interactions between lateral prefrontal and sensory cortexes. The mechanisms and representations for maintenance of more abstract, nonsensory information in WM are unknown, particularly whether such active...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Ikkai A,Blacker KJ,Lakshmanan BM,Ewen JB,Courtney SM

    更新日期:2014-10-15 00:00:00

  • Long-term, multisite, parallel, in-cell recording and stimulation by an array of extracellular microelectrodes.

    abstract::Here we report on the development of a novel neuroelectronic interface consisting of an array of noninvasive gold-mushroom-shaped microelectrodes (gMmicroEs) that practically provide intracellular recordings and stimulation of many individual neurons, while the electrodes maintain an extracellular position. The develo...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Hai A,Shappir J,Spira ME

    更新日期:2010-07-01 00:00:00

  • The human brain representation of odor identification.

    abstract::Odor identification (OI) tests are increasingly used clinically as biomarkers for Alzheimer's disease and schizophrenia. The aim of this study was to directly compare the neuronal correlates to identified odors vs. nonidentified odors. Seventeen females with normal olfactory function underwent a functional magnetic re...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Kjelvik G,Evensmoen HR,Brezova V,Håberg AK

    更新日期:2012-07-01 00:00:00

  • Octopamine stabilizes conduction reliability of an unmyelinated axon during hypoxic stress.

    abstract::Mechanisms that could mitigate the effects of hypoxia on neuronal signaling are incompletely understood. We show that axonal performance of a locust visual interneuron varied depending on oxygen availability. To induce hypoxia, tracheae supplying the thoracic nervous system were surgically lesioned and action potentia...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Money TG,Sproule MK,Cross KP,Robertson RM

    更新日期:2016-09-01 00:00:00

  • Extra force from asynchronous stimulation of cat soleus muscle results from minimizing the stretch of the common elastic elements.

    abstract::Rack and Westbury showed that low-frequency asynchronous stimulation of a muscle produces greater force compared with synchronous stimulation. This study tested the hypothesis that the difference results from the dynamic stretch of the common elastic elements. In eight anesthetized cats, the soleus was attached to a s...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Sandercock TG

    更新日期:2006-09-01 00:00:00

  • P2 receptor-mediated signaling in spherical bushy cells of the mammalian cochlear nucleus.

    abstract::Purinoreceptors of the P2 family contribute strongly to signaling in the cochlea, but little is known about the effects of purinergic neurotransmission in the central auditory system. Here we examine P2 receptor-mediated signaling in the large spherical bushy cells (SBCs) of Mongolian gerbils around the onset of acous...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Milenkovic I,Rinke I,Witte M,Dietz B,Rübsamen R

    更新日期:2009-09-01 00:00:00

  • Quantitative analysis of static strain sensitivity in human mechanoreceptors from hairy skin.

    abstract::1. Microelectrode recordings from 15 slowly adapting (SA) cutaneous mechanoreceptor afferents originating in hairy skin were obtained from the radial nerve in humans. 2. Controlled skin stretch was applied to the back of the hand that encompassed the physiological range of skin stretch during movements at the metacarp...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Edin BB

    更新日期:1992-05-01 00:00:00

  • Swimming movements elicited by electrical stimulation of turtle spinal cord. I. Low-spinal and intact preparations.

    abstract::1. Electrical stimulation applied within the dorsolateral funiculus of the spinal cord of an intact, unanesthetized turtle can elicit rhythmic limb movements similar to those observed during swimming. 2. A spontaneous display of hindlimb swimming movements is not observed in adult turtles whose spinal cord is transect...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Lennard PR,Stein PS

    更新日期:1977-07-01 00:00:00

  • Static and dynamic responses of periodontal ligament mechanoreceptors and intradental mechanoreceptors.

    abstract::1. The response properties of 39 periodontal ligament mechanoreceptors (PDLMs) and 12 intradental mechanoreceptors (IMs) related to the intact mandibular canine tooth were isolated by extracellular recording methods from the ipsilateral trigeminal semilunar ganglion. 2. The stimulus threshold and response magnitude of...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Dong WK,Shiwaku T,Kawakami Y,Chudler EH

    更新日期:1993-05-01 00:00:00

  • Influence of stimulus parameters on human postural responses.

    abstract::1. The role of sensory information in shaping muscle activation patterns to postural perturbations in humans was investigated by varying velocity, amplitude, or duration of the perturbing stimulus. Ten normal subjects were exposed to 120 backward translations of the support surface under conditions of varying velociti...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章


    authors: Diener HC,Horak FB,Nashner LM

    更新日期:1988-06-01 00:00:00