Abstract：
:Patients with Parkinson's disease (PD) have sentence comprehension difficulty, but it is unclear whether this is due to a deficit in grammatical processing or to an executive resource limitation. To assess grammatical processing in PD while minimizing task-related demands, PD patients and healthy control subjects performed a word detection procedure that assesses sensitivity to grammatical agreements in sentences in an "on-line" fashion. With this technique, we found that control subjects and PD patients are equally sensitive to grammatical agreement violations in sentences. A traditional, resource-demanding measure of sentence comprehension was also administered to the same PD patients. In comparison to healthy controls, PD patients were significantly impaired in their relative comprehension of sentences containing object-gap subordinate clauses compared to subject-gap subordinate clauses. Performance on several executive resource measures was also impaired in PD, and this correlated with their comprehension performance. Sensitivity to grammatical agreements with the word detection procedure, in the context of sentence comprehension difficulty on a traditional measure, suggests that PD patients' executive resource limitations contribute to their sentence comprehension difficulty.
journal_name
Brain Langjournal_title
Brain and languageauthors
Grossman M,Lee C,Morris J,Stern MB,Hurtig HIdoi
10.1006/brln.2001.2630subject
Has Abstractpub_date
2002-03-01 00:00:00pages
603-16issue
3eissn
0093-934Xissn
1090-2155pii
S0093934X01926306journal_volume
80pub_type
杂志文章abstract：:Script knowledge was examined in discourse produced by 15 mildly moderately impaired aphasics, 15 right-hemisphere-damaged (RHD) subjects. 15 neurological patients without central nervous system damage, and 30 normal controls. Experimental task were designed to elicit knowledge of particular scripts, various scripts f...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1996.0037
更新日期：1996-04-01 00:00:00
abstract：:In a study by Milberg, Blumstein, and Dworetzky (1987), normal control subjects and Wernicke's and Broca's aphasics performed a lexical decision task on the third element of auditorily presented triplets of words with either a word or a nonword as target. In three of the four types of word triplets, the first and the ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(89)90070-9
更新日期：1989-02-01 00:00:00
abstract：:The development of narrative content was studied in 100 children aged 6-15 years (49 with early-onset hydrocephalus and 51 age-matched controls) by analyzing transcripts of oral texts produced from their narrations of two fairy tales. In relation to those of their age-matched peers, the narratives of the children with...
journal_title：Brain and language
pub_type： 杂志文章,评审
doi：10.1006/brln.1994.1008
更新日期：1994-01-01 00:00:00
abstract：:Aphasic patients with restricted memory spans were assessed on their comprehension of syntactically simple sentences varying in numbers of content words and on their comprehension of sentences matched in content words but varying in syntactic complexity. Three different presentation modes were used: unlimited visual p...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(90)90099-3
更新日期：1990-01-01 00:00:00
abstract：:The brain may use two strategies to recover from poststroke aphasia: the structural repair of primarily speech-relevant regions or the activation of compensatory areas. We studied the cortical metabolic recovery in aphasic stroke patients with positron emission tomography (PET) at rest and during word repetition. The ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1998.1961
更新日期：1998-09-01 00:00:00
abstract：:It has often been suggested that the role of Broca's region in sentence comprehension can be explained with reference to general cognitive mechanisms (e.g. working memory, cognitive control). However, the (language-related) basis for such proposals is often restricted to findings on English. Here, we argue that an ext...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2009.09.004
更新日期：2009-12-01 00:00:00
abstract：:Skilled visual word recognition is thought to rely upon a particular region within the left fusiform gyrus, the visual word form area (VWFA). We investigated whether an individual (AA1) with pure alexia resulting from acquired damage to the VWFA territory could learn an alphabetic "FaceFont" orthography, in which face...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2013.11.005
更新日期：2014-02-01 00:00:00
abstract：:In a simple prime-target visual rhyming paradigm, pairs of words, nonwords, and single letters elicited similar event-related potential (ERP) rhyming effects in young adults. Within each condition, primes elicited contingent negative variation (CNV) while nonrhyming targets elicited more negative waveforms than rhymin...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2007.06.003
更新日期：2008-03-01 00:00:00
abstract：:In Spanish, objects and events at subject position constrain the selection of different forms of the auxiliary verb "to be": locative predicates about objects require "estar en", while those relating to events require "ser en", both translatable as "to be in". Subjective ratings showed that while the "object+ser+en" i...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2010.12.006
更新日期：2012-02-01 00:00:00
abstract：:The role of fronto-striatal regions in processing different language rules such as semantic and (grapho) phonological ones is still under debate. We have recently developed a lexical analog of the Wisconsin card sorting task which measures set-shifting abilities where the visual rules color, number, shape were replace...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2011.08.002
更新日期：2013-06-01 00:00:00
abstract：:This case report documents the partial recovery, over a 12-month period, of pure alexia in an adult female following a left occipital infarction. Measures of speed and accuracy were obtained on an oral reading and a lexical decision task immediately postonset and then on 10 subsequent occasions. Explicit letter-by-let...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(90)90148-a
更新日期：1990-10-01 00:00:00
abstract：:The present study examined the contribution of lexically based sources of information to acoustic-phonetic processing in fluent and nonfluent aphasic subjects and age-matched normals. To this end, two phonetic identification experiments were conducted which required subjects to label syllable-initial bilabial stop con...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1998.2049
更新日期：1999-03-01 00:00:00
abstract：:This study presents the results of an analysis of pragmatic aspects of language samples obtained from five agrammatic aphasic individuals prior to and following Linguistic Specific Treatment (LST). Clinically and statistically significant positive changes in informativeness and efficiency were documented in posttreatm...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.2001.2452
更新日期：2001-07-01 00:00:00
abstract：:Individuals with developmental dyslexia are often impaired in their ability to process certain linguistic and even basic non-linguistic auditory signals. Recent investigations report conflicting findings regarding impaired low-level binaural detection mechanisms associated with dyslexia. Binaural impairment has been h...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2006.07.001
更新日期：2007-07-01 00:00:00
abstract：:Does age constrain the outcome of all language acquisition equally regardless of whether the language is a first or second one? To test this hypothesis, the English grammatical abilities of deaf and hearing adults who either did or did not have linguistic experience (spoken or signed) during early childhood were inves...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/s0093-934x(03)00137-8
更新日期：2003-12-01 00:00:00
abstract：:Circuitry in ventral occipital-temporal cortex is essential for seeing words. We analyze the circuitry within a specific ventral-occipital region, the visual word form area (VWFA). The VWFA is immediately adjacent to the retinotopically organized VO-1 and VO-2 visual field maps and lies medial and inferior to visual f...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2012.04.010
更新日期：2013-05-01 00:00:00
abstract：:Using a cross-modal semantic priming paradigm, the present study investigated the ability of left-hemisphere-damaged (LHD) nonfluent aphasic, right-hemisphere-damaged (RHD) and non-brain-damaged (NBD) control subjects to use local sentence context information to resolve lexically ambiguous words. Critical sentences we...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/s0093-934x(03)00072-5
更新日期：2003-06-01 00:00:00
abstract：:Little is known about the relationship of reading speed and early visual processes in normal readers. Here we examined the association of the early P1, N170 and late N1 component in visual event-related potentials (ERPs) with silent reading speed and a number of additional cognitive skills in a sample of 52 adult Germ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2011.08.003
更新日期：2012-01-01 00:00:00
abstract：:Allen [Allen, M. D. (2005). The preservation of verb subcategory knowledge in a spoken language comprehension deficit. Brain and Language, 95, 255-264] presents evidence from a single patient, WBN, to motivate a theory of lexical processing and representation in which syntactic information may be encoded and retrieved...
journal_title：Brain and language
pub_type： 评论,杂志文章
doi：10.1016/j.bandl.2008.03.001
更新日期：2008-07-01 00:00:00
abstract：:In this paper we examine the tendency for agrammatic aphasics to make thematic reversal errors in comprehension, e.g., a tendency for English-speaking agrammatics to assign a preposed object the subject role. Although this tendency has been argued to follow from either a linear (Grodzinsky, 1995) or a directionality (...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1998.1988
更新日期：1998-11-01 00:00:00
abstract：:In this study we investigated the event-related potentials (ERPs) during the semantic judgment task (deciding if the two Chinese characters were semantically related or unrelated) to identify the timing of neural activation in children with early left brain damage (ELBD). The results demonstrated that compared with th...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2018.01.005
更新日期：2018-01-01 00:00:00
abstract：:This study investigated within-subject test-retest reproducibility (i.e., reliability) of language lateralization obtained with fMRI. Nine healthy subjects performed the same set of three different language tasks during two fMRI sessions on separate days (verb generation, antonym generation, and picture naming). A fou...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.2001.2600
更新日期：2002-03-01 00:00:00
abstract：:Bilinguals require a high degree of cognitive control to select the language intended for speaking and inhibit the unintended. Previous neuroimaging studies have not teased apart brain regions for generating the intention to use a given language, and those for speaking in that language. Separating these two phases can...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2015.03.004
更新日期：2015-05-01 00:00:00
abstract：:Published 100 years ago, Freud's monograph on aphasia, Zur Auffassung der Aphasien, is an incisive analysis of the so-called diagram-makers, those aphasiologists who would reduce brain and language to simple schemes of circumscribed cortical centers linked by unidirectional subcortical pathways. Chief architects of th...
journal_title：Brain and language
pub_type： 传,历史文章,杂志文章
doi：10.1016/0093-934x(92)90019-b
更新日期：1992-07-01 00:00:00
abstract：:Lexical access during speech comprehension comprises numerous computations, including activation, competition, and selection. The spatio-temporal profile of these processes involves neural activity in peri-auditory cortices at least as early as 200 ms after stimulation. Their oscillatory dynamics are less well underst...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2014.03.006
更新日期：2014-06-01 00:00:00
abstract：:Irony comprehension requires integration of social contextual information. Previous studies have investigated temporal aspects of irony processing and its neural substrates using psychological/electroencephalogram or functional magnetic resonance imaging methods, but have not clarified the temporospatial neural mechan...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2017.09.002
更新日期：2017-12-01 00:00:00
abstract：:Seven severely nonfluent aphasics and one relative or close friend were investigated in an interview situation. The conversation was videotaped and analyzed for the use of nonverbal communication between aphasic and partner. The results indicate that the group of aphasics used significantly more frequently and for a s...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(88)90053-3
更新日期：1988-01-01 00:00:00
abstract：:The role of attentional control in lexical ambiguity resolution was examined in two patients with damage to the left inferior frontal gyrus (LIFG) and one control patient with non-LIFG damage. Experiment 1 confirmed that the LIFG patients had attentional control deficits compared to normal controls while the non-LIFG ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2010.09.012
更新日期：2011-01-01 00:00:00
abstract：:Verbal humor deficits were investigated in right-hemisphere-damaged patients. It was hypothesized that the appreciation of jokes presupposes two elements: sensitivity to the surprise element entailed in the punch line of a joke and apprehension of the coherence which results when the punch line has been integrated wit...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(83)90002-0
更新日期：1983-01-01 00:00:00
abstract：:The study of cerebral specialization in persons with Down syndrome (DS) has revealed an anomalous pattern of organization. Specifically, dichotic listening studies (e.g., Elliott & Weeks, 1993) have suggested a left ear/right hemisphere dominance for speech perception for persons with DS. In the current investigation,...
journal_title：Brain and language
pub_type： 临床试验,杂志文章
doi：10.1006/brln.1998.2131
更新日期：1999-09-01 00:00:00
