Abstract：
:Matrix metalloproteinase-9 (MMP-9) is a member of the family of zinc-dependent endopeptidases that degrade extracellular matrix proteins. It can be activated by serine proteinases or by superoxide radicals. The motor neurons in amyotrophic lateral sclerosis patients express significantly higher levels of MMP-9, suggesting a role in neurodegeneration. The aim of the study was to investigate MMP-9 in cerebrospinal fluid from amyotrophic lateral sclerosis patients. MMP-9 was measured by enzyme-linked immunosorbent assay ELISA in cerebrospinal fluid from 24 amyotrophic lateral sclerosis patients and 15 controls. The mean amyotrophic lateral sclerosis duration was 18 months. According to Munsat ALS Health State Scale, the patients were divided into four groups: mild, moderate, severe, terminal. The patients were also divided into groups with shorter (below 12 months) and longer (above 12 months) duration of the disease. MMP-9 level was insignificantly lower in the cerebrospinal fluid from amyotrophic lateral sclerosis patients compared with controls. MMP-9 level showed a tendency to decrease with clinical status worsening, however this correlation was not statistically significant. The difference between MMP-9 level in the cerebrospinal fluid between the groups of patients with shorter and longer duration of amyotrophic lateral sclerosis was not significant.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Iłzecka J,Stelmasiak Z,Dobosz Bsubject
Has Abstractpub_date
2001-11-01 00:00:00pages
1035-43issue
6eissn
0028-3843issn
1897-4260journal_volume
35pub_type
杂志文章abstract：:The author studied the problem of differential diagnosis in cases with blood presence in the cerebrospinal fluid. Among 151 fluid samples obtained from 96 patients he found pathological admixture of blood in 117 samples and blood admixture as artifact in 34 samples. Besides the generally accepted differentiating crite...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The essential stage of Dolenc's approach to the cavernous sinus is the incision of the meningo-orbital fold (MOF) without damaging nervous structures in the superior orbital fissure. The goal of the research is to perform a topographic and morphometric study of the meningo-orbital fold. MATERIAL...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:The analysis of clinical features of groups of patients with frequent and rare epileptic seizures showed that the mean age of the first seizure, the mean age at the time of examination, and the mean duration of the disease were not significantly different in both studied groups. In the group with frequent seizures a s...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:We present a rare case of bilateral crocodile tears syndrome (CTS) in the course of Melkersson-Rosenthal syndrome. Melkersson-Rosenthal syndrome is characterised by a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue. The classic triad is infrequent and oligosymptomatic variants ar...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:One of the potential treatment methods of obesity is deep brain stimulation (DBS) of nucleus accumbens. We describe the case of 19 years old woman with hypothalamic obesity. She weighted 151.4 kg before DBS and the non-surgical methods proved to be inefficient. She was treated with implantation of DBS electrode to nuc...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.01.014
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:F-wave is a late response recorded from muscle elicited by electric impulse conveyed antidromically to alpha-motor neurons of the spinal cord. F-wave latency and frequency are assessed in routine electroneurography providing information of conduction in the proximal segment of the nerves. F-wave ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：:The following article presents current views on the possibility of pharmacological treatment of Parkinson's disease (PD). Research conducted on drugs with potentially neuroprotective effects has changed the way we viewed the treatment of early stages of PD. Beginning treatment with the application of dopamine agonists...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-05-01 00:00:00
abstract：:Cortico-basal degeneration (CBD) or cortico-basal ganglionic degeneration is a condition characterised by selective cortical atrophy of parietal and in a lesser extent, frontal lobe associated with dysfunction of the basal ganglia. The clinical symptoms of CBD, predominantly extrapyramidal signs (bradykinesia and rigi...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:Endovascular treatment of cerebral arteriovenous malformation (AVM) lies in selective catheterisation through feeder and AVM nidus. Sticking mixture is applied after proper verification of microcatheter location. Malformation embolisation is normal when the vessel net is of small diameter. In the presented case emboli...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Subcortical dementia is a clinical syndrome incorporating disorders of cognitive and affective sphere, which is caused by organic damage to subcortical structures. The syndrome is usually connected with Progressive Supranuclear Palsy, Huntington Disease, Parkinson's Disease. Subcortical dementia is mainly characterize...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：:Steroid receptors play an important role in homeostasis and in proliferation of neoplastic cells as well. Biological effect of steroid hormone on tissues depends on intracellular concentration of its receptor. The binding hormone with its receptor activates adequate genes in cellular nuclei and cell proliferation. The...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The authors report two cases of rarely observed arteriovenous malformations of the external carotid artery treated surgically. The diagnostic problems and own observations and methods of surgical treatment of these malformations are discussed. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：INTRODUCTION:Non-invasive bladder cancer is effectively treated with intravesical BCG therapy. The administration of the BCG vaccine is to destroy the neoplastic lesion or prevent further recurrences. The activity of the vaccine involves boosting the immune system through the stimulation of the inflammation in the blad...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2015.12.003
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Ongoing evaluation of the results of thrombolytic therapy in patients with ischaemic stroke (IS) in regions with different health care organization is absolutely crucial for making this method of treatment safer and efficient. The aim of this study was to analyse the efficacy and safety of treatm...
journal_title：Neurologia i neurochirurgia polska
pub_type： 临床试验,杂志文章
doi：10.5114/ninp.2013.36755
更新日期：2013-07-01 00:00:00
abstract：:Langerhans cell histiocytosis is a rare neoplasm that belongs to the histiocytic and dendritic cell neoplasm group according to the 2008 WHO classification. It has been defined as neoplastic proliferation of Langerhans cells that express CD1a and S-100 proteins and have Birbeck granules on the ultrastructural examinat...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/s0028-3843(14)60011-6
更新日期：2010-03-01 00:00:00
abstract：:The authors report the results of investigations of 33 healthy subjects and 33 patients with manifestations of intracranial circulatory disturbances in the vascularization area of the vertebrobasilar system. Type II rheography was used. All curves from the vertebral, vertebromastoid and frontomastoid leads were averag...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：:Using radioimmunoassay methods the authors assayed the concentration of biochemical neoplasm markers (BMN) in 106 patients with neurological diseases (M-56, F-50) in the serum, and in 20 cases in the cerebrospinal fluid. In certain cases these markers were present, and sometimes their concentration was raised: ferriti...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：:Multiple sclerosis (MS) should be differentiated with diseases causing disseminated lesions of central nervous system or imitating clinical course of MS. Clinical course and results of laboratory investigations also immunological tests should be taken into account in differential diagnosis of MS. We present four patie...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Headaches belong to the most frequent sufferings. According to certain most modern epidemiological studies about 20% of adults have recurrent headaches, among them particularly migraine and tension headache. In recent years the interest in these conditions had increased resulting in a great number of research works. A...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:The epilepsy treatment during pregnancy represents a balance between teratogenic hazard and seizure control. The aim of the study was to evaluate the safety and efficacy of lacosamide (LCS) during pregnancy and breastfeeding. METHODS:Patients referred to our Epilepsy Center for pregnancy planning who became...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2017.03.003
更新日期：2017-01-01 00:00:00
abstract：:The authors report a case of coexistence of Eales disease and multiple sclerosis in which signs of perivenous retinitis preceded by 25 years the appearance of neurological changes. Considering the similarity in the course of both disease and the histological character of perivascular changes the authors suggest presen...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：:The pathological mechanism of pain in vertebral column diseases is discussed in accordance with the theory of Melzack and Wall taking into account both systems of pain sensation control at the spinal level and reticular formation level. The action of pain mediators is discussed as well. The main pathogenetic factors a...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:Migraine is among the most mysterious diseases. It has been known for centuries but as yet it has resisted the advances in medicine and has not revealed its aetiology, mechanism of headache and possibilities of treatment. Various theories on the pathogenesis of migraine and arguments for and against them are reviewed ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:The problem of pathogenesis and effective treatment of traumatic optic neuropathy (TON) is still an open question. According to current opinions the immediate results of conservative treatment with megadose corticosteroids are similar to those obtained with surgical decompression. No data on late results of both modes...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:We studied the percentage of double positive (CD4+CD8+) form of T-cells in a group (total 77) multiple sclerosis (MS) patients, measured by means of monoclonal antibodies anti-CD3, CD4/FITC, CD8/RPE and flow cytometry FACScan (Becton Dickinson). In our study we have shown that the percentage of the double positive T c...
journal_title：Neurologia i neurochirurgia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:A case of pinealoma is described in a patient aged 16 years who had been treated initially conservatively with ventriculoperitoneal shunting and cobalt irradiation of the whole brain. The spine was not irradiated because of absence of histological examination. After 6 months the patient returned to hospital with parap...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：:All-night EEG records were obtained in 100 patients aged 14-48 years staying at a neurosurgical centre for various forms of focal epilepsy. In 84 cases discharges were observed during the nocturnal investigation. The morphology of the discharges depended on the phase of sleep during which they appeared. Discharges occ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Patients suffering from Huntington disease (HD) have been shown to present with poor self-awareness of a variety of symptoms. The study aimed to assess the self-awareness of memory impairment in HD in comparison to advanced Parkinson disease (PD), mild PD and cervical dystonia. MATERIAL AND METH...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.30262
更新日期：2012-07-01 00:00:00
abstract：:The author describes a 47-year-old patient in whom lingual hemiatrophy developed one month after angina. The development of hemiatrophy was preceded by occipital headaches and pain behind the ear on the side of hemiatrophy. In the differential diagnosis the author excluded inflammatory processes neoplasms and developm...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:Out of over 100 children with the Lennox-Gastaut syndrome observed in the Outpatient Clinic and Department of Paediatric Neurology, Children's Health Center the authors present 6 cases in which the course of the disease was progressive and devastating. The main signs were astatic-myoclonic and generalized seizures, re...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
