Abstract：
BACKGROUND AND PURPOSE:Ongoing evaluation of the results of thrombolytic therapy in patients with ischaemic stroke (IS) in regions with different health care organization is absolutely crucial for making this method of treatment safer and efficient. The aim of this study was to analyse the efficacy and safety of treatment with intravenous alteplase in patients with acute IS in a rural hospital. MATERIAL AND METHODS:Between 2006 and 2011, 1392 pa-tients with IS were treated (including 200 patients treated with alteplase; 14.37%). In patients treated with alteplase, we analysed the influence of several variables on the functional status after 3 months according to the modified Rankin Scale (mRS), case-fatality rate during 3 months after onset and symptomatic intracerebral haemorrhage (SICH). RESULTS:In the studied population, good outcome (mRS 0-2) at 3 months was related to younger age (p = 0.001), male sex (p = 0.02) and low scores (< 15 points) on the National Institutes of Health Stroke Scale (NIHSS) (p < 0.0001). Deaths within 3 months were related to older age (p = 0.027), female sex (p = 0.004), severity of stroke measured by NIHSS score (p < 0.0001) and presence of radiological signs of previous stroke in baseline computed tomography (CT)(p = 0.002). Patients with SICH had higher mean age (p = 0.014) and higher severity of neurological deficit measured on the NIHSS scale (p = 0.03). CONCLUSIONS:The indications for intravenous thrombolysis in patients with IS should be strictly analysed so that the treatment is effective and safe especially in older patients, patients with greater severity of neurological symptoms and patients with old post-stroke lesions in baseline CT.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Sobolewski P,Sledzińska-Dźwigał M,Szczuchniak W,Hatalska-Żerebiec R,Grzesik M,Sobota Adoi
10.5114/ninp.2013.36755subject
Has Abstractpub_date
2013-07-01 00:00:00pages
310-8issue
4eissn
0028-3843issn
1897-4260pii
S0028-3843(14)60372-8journal_volume
47pub_type
临床试验,杂志文章abstract：:Every year several thousands of operations on the cervical spine from anterior approach are performed in the world for decompression of spinal cord and nerve roots. It is estimated that in 0.2 to 12% of the operations serious intraoperative and postoperative complications occur. Such cases have been reported in the wo...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：:The presented case concerns a patient with neuralgia of the common peroneal nerve and progressive neurological deficit caused by interfascicular growth of schwannoma. The ultrasound diagnostics identified the lesion as a popliteal cyst. Magnetic resonance imaging revealed features of atypical cyst location. Due to the...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.30273
更新日期：2012-07-01 00:00:00
abstract：:In 23 patients with multiple sclerosis (group i) and 15 other subjects (group II) cell content of sterile exudate was studied in the skin window test of Rebuck. The results were compared. Cellular reaction of the skin was greater in group I than in group II and the difference was statistically significant. The number ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
abstract：:Intracranial pressure (ICP) pulse wave was analysed during infusion tests performed in hospital (hydrocephalus) and in cats. Pulse wave changes were evaluated calculating the high frequency centroid index (HFC) in the HFC, found to be a very valuable parameter in intracranial volume-pressure situation evaluation. The ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Parkinson disease (PD) is a risk factor for dementia. In addition, specific cognitive deficits can occur in PD patients without dementia. A patient's level of education could have an influence on the development of cognitive impairment in PD. The aim of this study was to examine the relationship ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/s0028-3843(14)60056-6
更新日期：2011-01-01 00:00:00
abstract：:Multi-infarct dementia (MID) and dementia of the Alzheimer type (DAT) are the main syndromes in the elderly. This study aims at evaluating the possible differentiation of these syndromes on a clinical basis. The patient population consisted of demented patients hospitalized during the period April 1, 1988-September 30...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:The main aim of the study was to find the effect of hyperdense middle cerebral artery sign (HMCAS), as the only admission computed tomography (CT) manifestation of ischemic stroke involving middle cerebral artery (MCA) region, on the extent of stroke measured by Alberta Stroke Program Early CT score (ASPECTS...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.10.003
更新日期：2017-01-01 00:00:00
abstract：:In 1974 an epidemic of lymphocytic cerebrospinal meningitis occurred in the Province of Bydgoszcz. Thirty-nine cases of this disease were hospitalized at the neurological department of the hospital in Grudziadz. Virological investigations demonstrated presence of Coxsackie A9 virus. The manifestations of the disease, ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1975-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to evaluate our surgical experience with intracranial meningiomas in NF2 patients and provide knowledge of the natural history of these lesions. METHODS:We included in the natural growth study patients with the diagnosis of NF2 who harbored intracranial meningiomas and were observed ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2015.08.007
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The aim of the study was to present the results of our management of frontal sinus fractures. MATERIALS AND METHODS:We analyzed records of 101 patients treated between 1996 and 2002, who sustained frontal sinus fractures. 7 patients were women and 94 were men. The average age of patients was 34 ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:The group of 20 patients with the preliminary diagnosis of occlusive hydrocephalus were treated by neuroendoscopic technique. Ten ventriculocystocisternostomies in cases with third ventricle arachnoid cysts accompanied by hydrocephalus, 9 ventriculostomies, and 1 ventriculostomy with fenestration of posterior fossa cy...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Textiloma is a term used for retained cottonoid or surgical sponge in the operation field. Although they occur mostly after thoracic or abdominal operation, they can also be encountered after surgery of extremities or the spine. There are few reports of spinal cases in which MR and CT imaging findings of textilomas ha...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2009-09-01 00:00:00
abstract：:Visual evoked potentials in response to checkerboard reversal pattern were evaluated in 160 patients: 24 with isolated retrobulbar optic neuritis, 100 with unquestionable and probable multiple sclerosis, 36 with paraparesis or with disseminated changes of unestablished aetiology (degenerative or inflammatory) and in 8...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:In the light of observation of 60 children aged from 4 months to 8 years followed for 4--6 years the author studied the stages of functional development of the paretic hand in hemiparesis in infantile cerebral palsy. It is concluded that the development of the functions of grasping and manipulation is retarded and dis...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:The paper contains a clinical analysis of 23 cases of dorsomedial intervertebral disc prolapse in the lumbar spine treated surgically with stress laid on late results, which were evaluated in follow up. The results were compared with the rate of increase of clinical manifestations, clinical conditions of the patients,...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:Investigations of biological rhythms were done in migraine relating the results to certain neurochemical and electroencephalographic studies. The obtained results demonstrated evident individual fluctuations of blood serotonin level in patients with migraine and in control groups. Correlations and connections were dem...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Marchiafava-Bignami disease (MBD) is a rare fatal neurological disorder characterized by demyelination, primary degeneration, and necrosis of the corpus callosum. Although MBD is mostly associated with chronic alcohol consumption and malnutrition, it has been reported in non-alcoholic patients. Serotonin syndrome is a...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2017.10.011
更新日期：2018-03-01 00:00:00
abstract：:100 all night sleep records in 90 patients with various forms of epilepsy and 10 patients with syncope were analyzed. There were 10 patients with generalized epilepsy, 41-with partial epilepsy with complex symptomatology and temporal foci, 23--with mixed seizures and frontal focal changes and 16 patients with partial ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：:The activity of the catecholaminergic system was studied by analysis of changes in the activity of dopamine beta-hydroxylase (DBH) in patients after subarachnoid haemorrhage treated conservatively or surgically. The activity of DBH was analysed in a group of 20 conservatively treated patients and 41 treated surgically...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：:All-night EEG records were obtained in 100 patients aged 14-48 years staying at a neurosurgical centre for various forms of focal epilepsy. In 84 cases discharges were observed during the nocturnal investigation. The morphology of the discharges depended on the phase of sleep during which they appeared. Discharges occ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:In a group of 360 patients the effects were studied of various management methods in case of lacking expansion of the brain after removal of chronic subdural haematoma on the therapeutic results. It was found that intrathecal infusion of normal saline was an effective procedure, with small frequency of transient compl...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:In a 57-year-old woman with a long history of multiple sclerosis a syndrome corresponding to the stiff-man syndrome was observed. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：BACKGROUND AND PURPOSE:People with mild cognitive impairment (MCI) have higher risk of developing dementia than the general population. Currently known risk factors for dementia include older age, low education level, gait disorders, hippocampal atrophy, and apolipoprotein E allele. Vascular risk factors may modify the...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Feasibility study and evaluation of complications of two different C1-C2 motion-sparing surgical methods for hangman's fracture of C2. MATERIAL AND METHODS:From 2001 till 2005, seventeen patients were operated on because of unstable type II (according to Effendi) hangman's fractures. The patient...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:A patient is reported with a history of subarachnoid haemorrhage and coexistent intracerebral and subdural haematomas. The source of haemorrhage were two pial arteriovenous fistulae supplied by the frontopolar artery. They coexisted with a meningeal arteriovenous fistula supplied by the anterior meningeal branch of th...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1988-11-01 00:00:00
abstract：:The frequency of dyskinesias connected with L-DOPA treatment of certain extrapyramidal system diseases was studied. Among 111 studied patients with Parkinson's disease drug-induced dyskinesias were observed in 56 cases (that is 50% of the treated patients) while in the group of other extrapyramidal system diseases (to...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:Peripheral facial paresis is a serious clinical and social problem. The effect of physical therapy in 44 patients aged 13-80 was studied. Idiopathic peripheral facial paresis was the cause of mimic muscles dysfunction in 75% of our patients. Medical treatment was conducted according to the established program, consist...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Follow-up examinations are reported of 218 patients with a history of reversible ischaemic stroke. The examinations were carried out 4 years after the onset of the disease which led to first hospitalization (1984-1987). It was possible to determine the frequency of repeated ischaemic episodes which developed in 27.5% ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:Arteriovenous malformations (AVMs) are the most dangerous congenital vascular malformations. Intracranial AVMs occur in about 0.1 percent of the population and account for 1 to 2 percent of all strokes. The angioarchitecture of AVMs consists of direct arterial to venous connections without an intervening capillary net...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：:The reported case was observed in a patient aged 54 years with disseminated lesions in the central nervous system. The history of the disease covered 18 years with periods of exacerbations and remissions. Seven years after the appearance of neurological signs involvement of the internal organs and skin was noted. In t...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
