[The current therapies for parkinson's disease. Part I: pharmacological treatment].

Abstract:

:The following article presents current views on the possibility of pharmacological treatment of Parkinson's disease (PD). Research conducted on drugs with potentially neuroprotective effects has changed the way we viewed the treatment of early stages of PD. Beginning treatment with the application of dopamine agonists decreases the risk of the occurrence of motor complications, particularly high with young individuals. The treatment of advanced stages of the disease currently requires the application of levodopa combined with other medicines, such as dopamine agonists or catechol-O-methyl transferase (COMT) inhibitors. Selecting treatment options should be individualized for each patient; it should take into account the variability of the clinical picture dependent on the progression of the disease, and the possibility of the occurrence of undesirable adverse effects of the drugs prescribed.

journal_name

Neurol Neurochir Pol

authors

Krygowska-Wajs A,Wszolek ZK,Uitti RJ,Słowinski J,Szczudlik A

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

665-76

issue

3

eissn

0028-3843

issn

1897-4260

journal_volume

37

pub_type

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