Abstract：
:The analysis of clinical features of groups of patients with frequent and rare epileptic seizures showed that the mean age of the first seizure, the mean age at the time of examination, and the mean duration of the disease were not significantly different in both studied groups. In the group with frequent seizures a significantly more frequent presence of features indicating serious organic brain damage was found (more frequent occurrence of known aetiological factors, more cases of posttraumatic epilepsy, psychic and neurological abnormalities). In group C changes in the background activity in EEG were also more frequent. The analysis of pharmacological treatment showed a more frequent application of polytherapy in group C. On the other hand, the mean levels of antiepileptic drugs in the serum and the mean doses of these drugs for kg of body mass were not significantly different in both groups. In about 40% of patients in both groups the prescribed drugs failed to reach the levels generally regarded as therapeutic (slightly more frequently in the group with rare seizures). This was true mainly of PHT since about 81% of patients in both groups failed to reach the therapeutic level of the drug (10 ug/ml). The likely causes of this fact were: too low doses prescribed (55% of the patients were given doses below the generally recommended), lower bioavailability of PHT (27% of patients had no therapeutic level of the drug in the serum, despite doses exceeding 5 mg/kg); or drug interaction. This requires elucidation in further studies.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Kuran W,Buksowicz C,Horyd W,Koziak M,Lipczyńska-Lojkowska W,Niedzielska K,Witkowska-Olearska Ksubject
Has Abstractpub_date
1986-01-01 00:00:00pages
12-7issue
1eissn
0028-3843issn
1897-4260journal_volume
20pub_type
杂志文章abstract：:Developmental abnormalities or inflammatory disorders provoke deformations and instability of the craniocervical junction. The most dangerous results of these lesions are: sudden brainstem compression or cervical myelopathy. The authors propose the guidelines for surgical management of non-traumatic deformities caused...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2002-03-01 00:00:00
abstract：:The author reviews two decades of clinical research directed towards the links between disturbances of the oculomotor functions and the severity and progress of Alzheimer's disease. Two basically different streams of research are identified. The first based on precise, quantitative examination of automatic or reflexiv...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：:The authors describe a case of spontaneous intracerebral haematoma treated conservatively. After three months a large posthaemorrhagic cyst of the brain was found in the sensorimotor area. The authors suppose that in case of surgical treatment the course of the disease and its sequelae would have been much milder. The...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:A patient is reported with a history of subarachnoid haemorrhage and coexistent intracerebral and subdural haematomas. The source of haemorrhage were two pial arteriovenous fistulae supplied by the frontopolar artery. They coexisted with a meningeal arteriovenous fistula supplied by the anterior meningeal branch of th...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1988-11-01 00:00:00
abstract：:Idiopathic Parkinson Disease accounts for approximately 75% of all cases of parkinsonism. The described case of Corticobasal Degeneration (CBD), until now not presented in Polish medical literature is a relatively rare example of so-called "parkinson plus" syndrome. The authors present the case of a 56 years old woman...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：:One of the potential treatment methods of obesity is deep brain stimulation (DBS) of nucleus accumbens. We describe the case of 19 years old woman with hypothalamic obesity. She weighted 151.4 kg before DBS and the non-surgical methods proved to be inefficient. She was treated with implantation of DBS electrode to nuc...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.01.014
更新日期：2016-01-01 00:00:00
abstract：:Based on 262 radiographic examinations done during two years the authors have analyzed the compatibility of the radiographic image with the clinical examinations and with the operation results. In the analysis the most frequently occurring lesion level having the character of hernia of the nucleus pulposus, age, sex, ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The aim of this retrospective study was to assess the effectiveness of aneurysm clipping by computed tomography angiography (CTA) in a long-term follow-up. MATERIAL AND METHODS:The CTA examination was performed in 119 patients who had 143 aneurysms clipped. The examinations were performed 3 to 1...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.31549
更新日期：2013-01-01 00:00:00
abstract：:The authors describe 32 cases of hydrocephalus of different aetiology in which the effectiveness of the ventriculoatrial shunt was evaluated by means of repeated computerized axial tomographic (CT) investigations. This investigation made it possible to demonstrate in a way not exposing the patients to any complication...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Multiple sclerosis (MS) should be differentiated with diseases causing disseminated lesions of central nervous system or imitating clinical course of MS. Clinical course and results of laboratory investigations also immunological tests should be taken into account in differential diagnosis of MS. We present four patie...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Results of DBS of ATN in refractory epilepsy depend on accuracy of the electrode's location. We searched for characteristic intraoperative, intracerebral EEG recording pattern from anterior thalamic nuclei (ATNs) as a biological marker for verifying the electrode's position. METHODS:There were six patients ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2018.01.003
更新日期：2018-01-01 00:00:00
abstract：:Deep brain stimulation (DBS) is a neurosurgical treatment of Parkinson's disease and other movement disorders. This surgical technique is applied to three brain targets: the ventral intermediate nucleus of the thalamus (Vim), the globus pallidus internus (Gpi) and the subthalamic nucleus (STN). Vim DBS improves contra...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-05-01 00:00:00
abstract：:The use of spinal implants in the pediatric population is controversial in terms of skeletal immaturity. The authors present the case of a 12-year-old boy with displaced Type III odontoid fracture, successfully treated by direct screw fixation. Fractures defined as Type II and Type III according to the classification ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:Benign tectal tumours in children constitute a distinct group of brainstem gliomas, characterised by a usually benign clinical course. The aim of this paper was a retrospective analysis of 1) results of conservative treatment, 2) diagnostic value of CT and MRI and 3) correlation of the MR image with the clinical cours...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：:Out of over 100 children with the Lennox-Gastaut syndrome observed in the Outpatient Clinic and Department of Paediatric Neurology, Children's Health Center the authors present 6 cases in which the course of the disease was progressive and devastating. The main signs were astatic-myoclonic and generalized seizures, re...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:Epidemiological investigations were carried out in an industrial plant in a population of about 16 000 people. The overall morbidity was 1 241.8 cases of nervous system diseases per 100 000 of population and the annual prevalence of neurological diseases was 473.7 per 100 000. The most frequent disease was sciatic pai...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:The author studied the problem of differential diagnosis in cases with blood presence in the cerebrospinal fluid. Among 151 fluid samples obtained from 96 patients he found pathological admixture of blood in 117 samples and blood admixture as artifact in 34 samples. Besides the generally accepted differentiating crite...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Mild head injury constitutes about 75% of all head injury cases. The post-concussion syndrome usually following a mild head injury is connected with numerous symptoms and not very severe signs. Research findings indicate that the symptoms related to mild head injuries persist for over 6 months in most patients. Accumu...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The outcome in acute stroke strongly depends on patient-related issues, as well as on the availability of human and diagnostic resources. Our aim was to evaluate safety and effectiveness of intravenous alteplase for stroke according to the time of admission to the hospital. MATERIALS AND METHODS...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2013.12.003
更新日期：2014-01-01 00:00:00
abstract：:The authors discuss a case of a 46 year-old man with bilateral internal carotid artery and right vertebral artery occlusion in unexpectedly good clinical state. The clinical diagnosis is documented by angiographic and doppler findings and brain CT scan. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:In the Province of Szczecin in the period 1993-1995 the incidence was 2.16 and the prevalence 55.32/100,000 on December 31 1995. Incidence and prevalence were higher in women (the difference was higher in Szczecin City) what was not connected with a significantly greater number of women in the population of the provin...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Commonly used classic hypoglossal (CN XII) to facial nerve (CN VII) anastomosis has the disadvantage of tongue hemiatrophy. Thus, various attempts have been made to modify this method to reduce the tongue damage. The aim of this report was to present the results of hemihypoglossal-facial nerve an...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/s0028-3843(14)60313-3
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Migraine is a common neurologic disorder whose etiology remains unknown. Migraine has been reported as a possible risk factor for ischemic stroke, especially in young women. The relationship between migraine and stroke is stronger in patients suffering from migraine with aura compared to those wi...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:Bioavailability of Phenytoin "Polfa" tablets was studied in comparison with Epanutin "Parke-Davis" capsules. It was found that the relative degree of bioavailability of Phenytoin in relation to Epanutin as a standard is 70,7 +/- 6,3% (SD). The cause of worse bioavailability of Phenytoin "Polfa" are differences in phar...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1978-05-01 00:00:00
abstract：:Peripheral nerves repairing using freeze-thawed skeletal muscle autografts were compared to conventional nerve grafts with respect to their electrical properties. It was found that the amplitude and distal latency of action potentials in both groups were not significantly different 3 and 6 months after the operation. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Plasma exchange under controlled haemodilution was tried in 9 patients with Guillain-Barré syndrome repeating the procedure at 24-hour intervals for from 7 to 17 times with a total exchange of plasma ranging from 2.0 to 4.9 litres. All patients had significant paresis or paralysis of all four extremities, and 3 had ad...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：:Tiagabine (TGB) is a novel anti-epileptic drug providing new therapeutic possibilities to patients with focal seizures resistant to treatment. Since there is no clear algorithm for the best add-on therapy, the aim of our work was to establish factors that statistically significantly affect tiagabine efficacy and toxic...
journal_title：Neurologia i neurochirurgia polska
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：2003-05-01 00:00:00
abstract：:Investigations were performed on 13 cats with epileptogenic focus developed after sectioning the optic chiasm and corpus callosum. Learning was begun 3 months after producing the epileptogenic focus by the aluminium method when it was bioelectrically active. Additionally in 6 cats DPH in daily doses of 10--15 mg/kg wa...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-03-01 00:00:00
abstract：:Cervicothoracic junction and upper thoracic spine down to T4 can be reached through anterior approach via sternotomy. Transsternal approach is the best route to gain access to lesions localized within vertebral bodies of the upper thoracic spine allowing for their resection, interbody fusion and replacement with bone ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:The authors report a case of Jakob-Creutzfeldt disease diagnosed at autopsy. In the discussion attention is called to characteristic clinical manifestations and possibilities of intravital diagnosis of the disease. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
