[Evaluation of the bioavailability of Polfa phenytoin tablets].

Abstract:

:Bioavailability of Phenytoin "Polfa" tablets was studied in comparison with Epanutin "Parke-Davis" capsules. It was found that the relative degree of bioavailability of Phenytoin in relation to Epanutin as a standard is 70,7 +/- 6,3% (SD). The cause of worse bioavailability of Phenytoin "Polfa" are differences in pharmaceutical forms of both preparations. The necessity to increase an average dose of Phenytoin "Polfa" tablets is suggested to gain optimal concentration of diphenyl-hydantoin in serum, in therapeutic range.

journal_name

Neurol Neurochir Pol

authors

Lazowski J,Lypka A,Zadrozyńska E,Pakszys W

subject

Has Abstract

pub_date

1978-05-01 00:00:00

pages

251-5

issue

3

eissn

0028-3843

issn

1897-4260

journal_volume

12

pub_type

杂志文章
  • [Clinical and differential diagnosis of multi-infarct dementia and Alzheimer's disease].

    abstract::Multi-infarct dementia (MID) and dementia of the Alzheimer type (DAT) are the main syndromes in the elderly. This study aims at evaluating the possible differentiation of these syndromes on a clinical basis. The patient population consisted of demented patients hospitalized during the period April 1, 1988-September 30...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Jura E

    更新日期:1992-01-01 00:00:00

  • Clinical course and management of intracranial meningiomas in neurofibromatosis type 2 patients.

    abstract:OBJECTIVE:The aim of this study is to evaluate our surgical experience with intracranial meningiomas in NF2 patients and provide knowledge of the natural history of these lesions. METHODS:We included in the natural growth study patients with the diagnosis of NF2 who harbored intracranial meningiomas and were observed ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2015.08.007

    authors: Nowak A,Dziedzic T,Czernicki T,Kunert P,Marchel A

    更新日期:2015-01-01 00:00:00

  • Absorbable sutures for the achievement of stable osteosynthesis in surgery for craniosynostosis.

    abstract:AIM OF THE STUDY:The goal of the present study was to analyse the exclusive use of absorbable suture material (Vicryl) in the fixation of transposed bone segments in cranial vault reshaping without modification of the osteotomy design. CLINICAL RATIONALE FOR THE STUDY:In the surgical correction of craniosynostosis, bo...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.5603/PJNNS.a2019.0014

    authors: Horn F,Kilipiris E,Pinzon J,Tsolakis I,Kabat M,Petrik M,Kuniakova D

    更新日期:2019-01-01 00:00:00

  • [Diagnostic difficulties in a case of vasogenic lateral pontine syndrome].

    abstract::A 54-year-old male patient is reported in whom progression of clinical manifestations, neurological signs and results of ancillary investigations suggested a cerebellopontine angle tumour in the initial stage of the disease. Further observation and additional appearance after 10 months of signs evidencing damage to ot...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Niemczewska M,Skrobisz M,Kida E

    更新日期:1986-01-01 00:00:00

  • [Dissecting aneurysm of the posterior inferior cerebellar artery].

    abstract::A 23 year old woman with dissecting aneurysm of the left posterior inferior cerebellar artery located distal to the branch feeding medulla oblongata is described. Trapping of the aneurysm with the aid of 2 clips was without any influence on neurological state of the patient and prevented recurrent hemorrhage. ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Kopera M,Majchrzak H,Ladziński P,Stech W,Maliszewski M

    更新日期:1992-11-01 00:00:00

  • [Whipple's disease--a rare cause of neurological symptoms and disorders].

    abstract::Whipple's disease is a chronic infection caused by Gram-positive bacillus Thropheryma Whippelii picture with a wide range of clinical manifestation, not only systemic but also neurological. Seronegative arthritis or arthralgia may be the only presenting symptom, predating by years gastrointestinal, and also pulmonary,...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Słowik A,Szczudlik A

    更新日期:2002-09-01 00:00:00

  • [Epidemiology of cerebral stroke in Poland].

    abstract::In Poland the annual incidence of cerebral stroke is 60,000 and half these patients die within one year, while the remaining one-half has permanent consequences of central nervous system damage. The incidence of stroke is in Poland similar to that in other European countries /the incidence rate is 177/100,000 in males...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Członkowska A,Ryglewicz D

    更新日期:1999-01-01 00:00:00

  • [Symptoms accompanying epileptic attacks].

    abstract::The author analysed 124 cases of grand mal seizures in patients aged above 16 years observed for 2 to 15 years finding sporadic tongue or oral mucosa biting in 55.7% of cases, involuntary passing of urine in 49%, simultaneous occurrence of both these signs in 37% defection in 8.1%, ejaculation in 1.6%, conjunctival o ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Nowak S

    更新日期:1984-05-01 00:00:00

  • [Problems in the selection of surgical approach for the treatment of non-traumatic deformities of the craniocervical junction].

    abstract::Developmental abnormalities or inflammatory disorders provoke deformations and instability of the craniocervical junction. The most dangerous results of these lesions are: sudden brainstem compression or cervical myelopathy. The authors propose the guidelines for surgical management of non-traumatic deformities caused...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Radek A,Zapałowicz K,Maciejczak A,Karbownik J,Grochal M,Radek M,Błaszczyk B,Skiba P

    更新日期:2002-03-01 00:00:00

  • [Lateral ventricle choroid plexus papillomas in infants].

    abstract::Choroid plexus papillomas are rare intracranial tumours occurring most frequently in children. In the period 1983-1988 in the neurosurgery department 10 infants were treated for choroid plexus papillomas. Their age was from 4 weeks to 12 months. The diagnosis was based on the results of ultrasonography and CT. Eight p...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Wocjan J,Boratyński W,Barszcz S

    更新日期:1993-01-01 00:00:00

  • Clinical phenotype heterogeneity in a family with ε-sarcoglycan gene mutation.

    abstract:AIM OF THE STUDY:This paper describes six cases of patients with myoclonus-dystonia syndrome who are members of a family in which an SGCE gene mutation has been confirmed. CLINICAL RATIONALE FOR THE STUDY:Myoclonus-dystonia syndrome is a very rare disease, with an incidence in Europe of about 2 in every million. Due t...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.5603/PJNNS.a2020.0005

    authors: Kaczyńska J,Jamrozik Z,Szubiga M,Rudzińska-Bar M,Janik P

    更新日期:2020-01-01 00:00:00

  • The 'radical combined approach' in cerebral arteriovenous malformation treatment: Technical note.

    abstract::AVMs are vessel anomalies where a connection between arterial and venous systems is present and the capillary bed is absent between the two. AVMs tend to present with seizures, headaches, focal neurological deficits and hemorrhage. Hemorrhage is the most common form of presentation. AVM's have a 2-4% annual risk of he...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2017.08.001

    authors: Kocaman U,Dalbasti T,Yildirim UM,Yilmaz H

    更新日期:2017-01-01 00:00:00

  • [The usefulness of neurological and radiological signs in lumbar discopathy].

    abstract::The aim of the work was to show the usefulness of neurological and radiological signs in the patients with L4 and L5 discopathy. The axial symptoms with the highest occurrence frequency and the differential symptoms closely connected with definite disc pathology: the type and/or the level of discopathy were defined. T...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Sobolewski P

    更新日期:1998-05-01 00:00:00

  • [Dopamine agonists--clinical applications beyond Parkinson's disease].

    abstract::Contemporary experience and results of clinical trials concerning dopamine agonist application in the treatment of many different diseases (apart from Parkinson's disease) are presented in the paper. A basic clinical recommendation for agonists is restless legs syndrome. In this syndrome almost all agonists give a con...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Kuran W

    更新日期:2007-03-01 00:00:00

  • Clinical features and risk factors of angiography headache and evaluation of its relationship to primary headaches - an important but neglected problem.

    abstract:INTRODUCTION:The authors of the article published in the current edition a single-centre prospective cohort study featuring patients who had undergone a diagnostic cerebral angiography procedure and who had experienced a headache associated with the procedure [1]. The authors of 'Clinical features and risk factors of a...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.5603/PJNNS.a2019.0057

    authors: Domitrz I

    更新日期:2019-01-01 00:00:00

  • [Comparison of results of polygraphic sleep studies and cerebrospinal fluid pressure records in patients following removal of supratentorial expanding lesions].

    abstract::In 4 patients operated upon for supratentorial brain tumors the authors carried out on the 3rd day after the operation polygraphic recording of nocturnal sleep with simultaneous measurements of cerebrospinal fluid pressure in the ventricular system by the method of Lundberg. A comparison of polygraphic records of noct...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Darwaj B,Moszyński K,Koźniewska H,Czochra T,Smyk K

    更新日期:1977-09-01 00:00:00

  • [Two cases of ophthalmic zoster follow by hemiplegia].

    abstract::Two cases of ophthalmic zoster are reported in which several weeks after the appearance of skin changes hemiplegia developed. In one case the clinical course was unfavourable, and on autopsy extensive vasculitis was found in the brain with ischaemic foci situated mainly on the side of zoster. In the second case with f...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Członkowska A,Kruszewska J,Szpakowa G,Tarnowska-Dziduszko E,Kryst-Widźgowska T

    更新日期:1991-01-01 00:00:00

  • [A case of metastasis of a pineal germinoma to the vertebral canal].

    abstract::A case of pinealoma is described in a patient aged 16 years who had been treated initially conservatively with ventriculoperitoneal shunting and cobalt irradiation of the whole brain. The spine was not irradiated because of absence of histological examination. After 6 months the patient returned to hospital with parap...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Kurzaj E,Kloc W

    更新日期:1986-09-01 00:00:00

  • [L-dopa with inhibitor in the treatment of parkinsonian syndrome-results of long-term observations].

    abstract::The report is based on the observation of 39 patients with parkinsonian syndromes treated with L-DOPA with inhibitor, including 30 patients treated during 2-6 years. It was found that treatment with L-DOPA with the inhibitor gave good or very good results in most patients with these syndromes with a relatively good dr...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Wasilewski R

    更新日期:1981-07-01 00:00:00

  • Deep brain stimulation of the right nucleus accumbens in a patient with Tourette syndrome. Case report.

    abstract::We describe the effects of unilateral right-sided nucleus accumbens (NA) stimulation in a patient with intractable Gilles de la Tourette syndrome (GTS) with associated compulsions and self-injurious behaviour. Pharmacological and behavioural therapies had completely failed to control the patient's tics and compulsions...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Zabek M,Sobstyl M,Koziara H,Dzierzecki S

    更新日期:2008-11-01 00:00:00

  • Significance of noncompliance when treating patients with epilepsy.

    abstract:INTRODUCTION:The absence of patient's cooperation when it comes to his/her treatment ("noncompliance") is typical to chronic diseases and it is significant problem in medical practice. The term "compliance" means patient's capability of strictly adhering to the recommendations concerning the prescribed treatment. The n...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2017.10.005

    authors: Kuzmanova R,Stefanova I,Stambolieva K

    更新日期:2018-03-01 00:00:00

  • Is there a bad time for intravenous thrombolysis? The experience of Polish stroke centers.

    abstract:BACKGROUND AND PURPOSE:The outcome in acute stroke strongly depends on patient-related issues, as well as on the availability of human and diagnostic resources. Our aim was to evaluate safety and effectiveness of intravenous alteplase for stroke according to the time of admission to the hospital. MATERIALS AND METHODS...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2013.12.003

    authors: Karliński M,Kobayashi A,Sobolewski P,Lisewski P,Romanowicz S,Fryze W,Nyka W,Zięba M,Dorobek M,Członkowska A

    更新日期:2014-01-01 00:00:00

  • [Newly formed intracranial saccular aneurysms revealed within several years after surgery for the aneurysm with different localization: report of 2 cases].

    abstract::The authors present two patients treated surgically for intracranial aneurysms. Within 2.5 and 4.6 years after surgery the repeated angiography performed after the second SAH revealed newly formed aneurysms in another localisation. These facts became a contribution to the etiopathogenetic considerations. ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Latka D,Szydlik W,Kozub D,Mrówka R

    更新日期:1995-07-01 00:00:00

  • [The use of doppler color ultrasonography in the evaluation of superior sagittal sinus patency in operations for parasagittal meningiomas].

    abstract::The authors present the possibility of replacement of invasive angiography by non-invasive, safer, more accurate USG-colour Doppler performed during the operation to estimate the permeability of superior sagittali sinus in falx meningioma cases. Based on the presented case they discuss the advantages of this method in...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Sokólska E,Harat M,Bronisz K

    更新日期:1999-01-01 00:00:00

  • [Embolitic material (coils) dislocation inside a giant and cerebral aneurysm and morphological aneurysm changes after coiling. Case report].

    abstract::The placement of tungsten coils into aneurysm sack in patient after SAH is a method of treatment used in many neurosurgical departments. The main indications for coiling procedures are severe neurological status (IV i V according to WFNS) and posterior circulation aneurysms. Coiling can be offered to a patient who doe...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Andrychowski J,Czernicki Z

    更新日期:2001-11-01 00:00:00

  • [A rare case of intracranial hematoma complicating bacterial endocarditis].

    abstract::Endocarditis is an infectious and inflammatory disease of cardiac valves with other coexisting symptoms affecting heart and other organs and systems. Patients with cardiac valves diseases are in the group of high risk. The authors present a case of successfully treated endocarditis affecting mitral valve prosthesis in...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Michalska-Krzanowska G,Dybkowska K,Badowicz B

    更新日期:1999-05-01 00:00:00

  • [Characteristics of the clinical features and pharmacological treatment of epileptics with frequent seizures].

    abstract::The analysis of clinical features of groups of patients with frequent and rare epileptic seizures showed that the mean age of the first seizure, the mean age at the time of examination, and the mean duration of the disease were not significantly different in both studied groups. In the group with frequent seizures a s...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Kuran W,Buksowicz C,Horyd W,Koziak M,Lipczyńska-Lojkowska W,Niedzielska K,Witkowska-Olearska K

    更新日期:1986-01-01 00:00:00

  • [Risk of hemorrhage and size of hematoma in patients with cerebral arteriovenous malformations].

    abstract::The occurrence of intracranial haemorrhage, epileptic seizures and focal neurological signs was estimated in the group of 40 patients with AVMs. Size of AVM, its localization was established by angiography. Maximum diameter of a haematoma was measured on preoperative CT. We found that small AVMs (diameter < 3 cm) are ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Majchrzak H,Dragan T

    更新日期:2000-09-01 00:00:00

  • Evaluation of activities of daily living in patients with slowly progressive neuromuscular diseases.

    abstract::Slowly progressive neuromuscular diseases include but are not limited to: facioscapulohumeral muscular dystrophy (FSHD) and limb-girdle muscular dystrophy (LGMD), hereditary motor and sensory neuropathy (HMSN) and spinal muscular atrophy type III (SMA3). The purpose of this study is to present an evaluation of basic a...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2017.10.007

    authors: Bienias K,Ścibek J,Cegielska J,Kochanowski J

    更新日期:2018-03-01 00:00:00

  • [Platelet membrane fluidity and receptor exposition in patients with Alzheimer's disease].

    abstract::The majority of reports indicate that blood platelet membrane fluidity is increased in Alzheimer's disease (AD) patients. The increased membrane fluidity implies that platelet membrane receptors are less exposed to the external environment. To verify this hypothesis we tried to estimate platelet membrane fluidity at i...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Kozubski W,Swiderek M,Kłoszewska I,Watała C,Gwoździński K

    更新日期:1999-11-01 00:00:00