Abstract：
:The report is based on the observation of 39 patients with parkinsonian syndromes treated with L-DOPA with inhibitor, including 30 patients treated during 2-6 years. It was found that treatment with L-DOPA with the inhibitor gave good or very good results in most patients with these syndromes with a relatively good drug tolerance during the first three months. With passing time the effect of the drug on the manifestations of the disease decreases and the tolerance becomes aver worse. The results of the treatment are worse although the applied daily dose is increased by a metan value of 50%. AT the same time the frequency of such complications as hyperkineses, anxiety and depression labyrinthine-cerebellar signs increases. Urinary passage disturbances and mental degradation develop and their temporal association with L-DOPA treatment is unquestionable, while a cause-and-effect correlation seems likely. In the conclusion the author suggests the need for a careful consideration of each decision of treatment with L-DOPA, and the possibility of improving the results of parkinsonism treatment is seen in the production of new optimal forms of he already present drugs, monitoring blood drug levels, and practical utilization of the synergism between the group of drugs stimulating the dopaminergic system and the group of drugs inhibiting the acetylcholinergic system.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Wasilewski Rsubject
Has Abstractpub_date
1981-07-01 00:00:00pages
411-6issue
4eissn
0028-3843issn
1897-4260journal_volume
15pub_type
临床试验,杂志文章abstract：:Epidural lipomatosis is most frequently seen in patients on chronic steroid treatment. Only fourteen cases of idiopathic spinal epidural lipomatosis have been described. In this report we present an additional case of this condition in a 38 year-old man. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The authors present the possibility of replacement of invasive angiography by non-invasive, safer, more accurate USG-colour Doppler performed during the operation to estimate the permeability of superior sagittali sinus in falx meningioma cases. Based on the presented case they discuss the advantages of this method in...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：INTRODUCTION:Gliomas are commonly associated with the development of epilepsy; in some cases the two conditions share common pathogenic mechanisms and may influence each other. Brain tumor related-epilepsy (BTRE) complicates the clinical management of gliomas and can substantially affect daily life. STATE OF THE ART:T...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/j.pjnns.2018.06.001
更新日期：2018-08-01 00:00:00
abstract：:Inhibitory effect of botulinum toxin on acetylcholine release from the neurons of peripheral nervous system and morphological changes produced in neuro-muscular junction by administration of the toxin are discussed. Other possible mechanisms of action, which can be responsible for the therapeutic effect are presented....
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:The authors report two cases of rarely observed arteriovenous malformations of the external carotid artery treated surgically. The diagnostic problems and own observations and methods of surgical treatment of these malformations are discussed. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Current classification of primary progressive aphasia (PPA) encompasses three variants: non-fluent (nfvPPA), semantic (svPPA) and logopenic (lvPPA). Previously lvPPA was regarded as aphasic form of Alzheimer's disease (AD). However, not all patients with lvPPA phenotype present with AD pathology. Despite abundant lite...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2015.06.001
更新日期：2015-01-01 00:00:00
abstract：:Adrenoleukodystrophy (ALD) is a hereditary disease related to abnormalities in the structure and function of peroxisomes. The nature of disorder arises from defective process of beta-oxidation of very-long-chain fatty acids and their accumulation in various organs. ALD may present as a few phenotypes urologic symptoma...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:A statistical analysis of CSF lactate concentration and CSF pH and PCO2 was performed. The values were obtained from 211 samples taken from 76 neurosurgical patients. The values of pH and pCO2 were classified in three groups corresponding to the following three ranges of lactate concentration: below 15 mg%, 15-30 mg%,...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:In Poland the annual incidence of cerebral stroke is 60,000 and half these patients die within one year, while the remaining one-half has permanent consequences of central nervous system damage. The incidence of stroke is in Poland similar to that in other European countries /the incidence rate is 177/100,000 in males...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：:Mild head injury constitutes about 75% of all head injury cases. The post-concussion syndrome usually following a mild head injury is connected with numerous symptoms and not very severe signs. Research findings indicate that the symptoms related to mild head injuries persist for over 6 months in most patients. Accumu...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：:Conventional methods of neuroimaging, such as computed tomography and magnetic resonance imaging, are mostly useful in exclusion of movement disorders with secondary aetiology. Recently, the application of transcranial sonography has been introduced to the diagnosis of extrapyramidal diseases. This valuable technique,...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/s0028-3843(14)60155-9
更新日期：2010-11-01 00:00:00
abstract：:Benign tectal tumours in children constitute a distinct group of brainstem gliomas, characterised by a usually benign clinical course. The aim of this paper was a retrospective analysis of 1) results of conservative treatment, 2) diagnostic value of CT and MRI and 3) correlation of the MR image with the clinical cours...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：:Cortico-basal degeneration (CBD) or cortico-basal ganglionic degeneration is a condition characterised by selective cortical atrophy of parietal and in a lesser extent, frontal lobe associated with dysfunction of the basal ganglia. The clinical symptoms of CBD, predominantly extrapyramidal signs (bradykinesia and rigi...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:Forty-five cases of pituitary adenomas with clinical characteristics of acromegaly treated surgically from an approach through the nose and sphenoid sinus are presented. After the operation the somatic features of acromegaly decreased in 66% of cases, headaches regressed in 88%, visual field defects disappeared in 20%...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Migraine is a common neurologic disorder whose etiology remains unknown. Migraine has been reported as a possible risk factor for ischemic stroke, especially in young women. The relationship between migraine and stroke is stronger in patients suffering from migraine with aura compared to those wi...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:The superficial siderosis (SS) of the central nervous system (CNS) is a rare condition characterized by a wide range of neurological manifestations directly linked to an acquired iron-mediated neurodegeneration. First described more than 100 years ago, only recently SS has been divided into two distinct entities, acco...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/j.pjnns.2017.10.006
更新日期：2018-01-01 00:00:00
abstract：:Ischaemic stroke in thromboembolic mechanism may be a first sign of neoplastic disease, as in the presented case of a 56-year-old woman. Progressive trombocytopenia, anaemia with reticulocytosis and schistocytes in peripheral blood smear, elevated serum LDH activity as well as coexisting myocardial infarction initiall...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:A new quantitative motor unit potential (MUP) analysis method, called Multi-MUP analysis, is described. Multi-MUP analysis is a type of decomposition analysis of the EMG signal. At each recording site six different MUPs may be recorded during an epoch of 4.8 sec. A study of 20-30 MUPs including editing takes 3-7 minut...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：:The aim of the work was to evaluate effect of CoQ10 on the lactate level in the rat brain after administration of Et-1. Fifty-three male Wistar rats (approximately 220-250 g) were used in the experiment. The animals were divided into four groups. 1. control; 2-4 under chloride hydrate anaesthesia, the rats were subjec...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The objective of the study was to assess bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) for patients with advanced Parkinson disease (PD). MATERIAL AND METHODS:The study population included 5 patients with bilateral STN DBS who completed a 5-year postoperative follow-up period....
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/s0028-3843(14)60401-1
更新日期：2010-01-01 00:00:00
abstract：:The preliminary studies on cerebral blood flow changes during neuropsychologic tests were carried out using transcranial Doppler sonography (TCD). The procedure with the standardized cerebral activation in order to obtain the control brain activity level was elaborated and tested. Blood flow velocity changes were meas...
journal_title：Neurologia i neurochirurgia polska
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1994-11-01 00:00:00
abstract：:The authors present a case of Huntington disease in a 14 year old boy. The basis of genetic, pathoetiology, clinical course of disease, significance of molecular analysis of DNA are discussed. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:The per cent and absolute numbers of lymphocytes T and B were calculated in 37 patients with hereditary diseases of the nervous system (torsion dystonia, hepatolenticular degeneration, idiopathic tremor) and in 22 donors. Reactions of active and full spontaneous complement-induced formation of rosettes and B cell dete...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:The authors present four cases of acute epidural hematoma (three supratentorial and one in the posterior fossa), in which non-operative treatment was performed. The conditions to undertake this treatment were: good clinical and neurological state of the patients on admission (GCS equal or more than 14), absence or mil...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:There are only a few investigations in the literature, that address the occurrence and the role of anticardiolipin antibodies (aCL) in children with migraine. The results of those studies are often contradictory. The aim of the study was to determine if the values of aCL in children with migraine...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:The authors present the results of own investigations on the occurrence of side effects following myelography with the contrast medium Amipaque administered usually by the lumbar route. Sixty patients aged 21-65 years with various diseases of the spinal cord and cauda equina were studied. Clinical and myelographic inv...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:A group of 69 patients aged 60-80 years with brain tumours were analysed, estimating the surgical risk at the time of qualification for operations. Surgical treatment was given to 36 patients limiting it to lobectomy of the part of the brain containing the greater part of the tumour. The peri-operational mortality was...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:Numerous factors are involved in the pathogenesis of Parkinson's disease, including inflammation in certain regions of the brain. Studies suggest a significant role of microglia in dopaminergic cell injury. Cytokines and apoptosis-related proteins were elevated in the brain and cerebrospinal fluid. The occurrence of a...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:Choroid plexus papillomas are rare intracranial tumours occurring most frequently in children. In the period 1983-1988 in the neurosurgery department 10 infants were treated for choroid plexus papillomas. Their age was from 4 weeks to 12 months. The diagnosis was based on the results of ultrasonography and CT. Eight p...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Differential diagnosis in the material was based on the neurological and radiological findings made in 45 patients with third-ventricle tumours and 133 with subtentorial tumours. No clinical syndrome has been found which could help in reliable diagnosis concerning either of these locations of the tumour. Of decisive s...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
