Bilateral subthalamic nucleus stimulation in the treatment of advanced Parkinson's disease. Five years' personal experience.

Abstract:

BACKGROUND AND PURPOSE:The objective of the study was to assess bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) for patients with advanced Parkinson disease (PD). MATERIAL AND METHODS:The study population included 5 patients with bilateral STN DBS who completed a 5-year postoperative follow-up period. In all patients electrodes (Model 3387 or 3389) were stereotactically bilaterally inserted into the STN using a Leksell stereotactic G frame. The clinical rating tests included Unified Parkinson's Disease Rating Scale (UPDRS) and two motor-timed tests derived from CAPIT (rapid movements between two points and stand-walk-sit test). All patients were assessed in off and on condition before implantation and 1, 3 and 5 years in medication on and off condition and stimulation on condition and stimulation off condition. To compare preoperative to postoperative UPDRS scores, only mean values and standard deviations are presented because of the small study population. RESULTS:The stimulation effect was noted in the off state, resulting in a 59% improvement in motor scores of UPDRS at 5-year follow-up, when compared to preoperative scores. In the on state the stimulation improved motor scores by 17%. At 5-year follow-up, reduction of daily levodopa dose was 50%. CONCLUSIONS:Bilateral STN DBS is an effective and safe treatment for patients with advanced PD. Bilateral STN DBS contributes to improvement of parkinsonian symptoms in the off state and levodopa-induced dyskinesia. This can be correlated with a 50% reduction of daily levodopa dose 5 years postoperatively.

journal_name

Neurol Neurochir Pol

authors

Zabek M,Sobstyl M,Koziara H,Kadziołka B,Mossakowski Z,Dzierzecki S

doi

10.1016/s0028-3843(14)60401-1

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

3-12

issue

1

eissn

0028-3843

issn

1897-4260

pii

S0028-3843(14)60401-1

journal_volume

44

pub_type

杂志文章
  • [Two cases of ophthalmic zoster follow by hemiplegia].

    abstract::Two cases of ophthalmic zoster are reported in which several weeks after the appearance of skin changes hemiplegia developed. In one case the clinical course was unfavourable, and on autopsy extensive vasculitis was found in the brain with ischaemic foci situated mainly on the side of zoster. In the second case with f...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Członkowska A,Kruszewska J,Szpakowa G,Tarnowska-Dziduszko E,Kryst-Widźgowska T

    更新日期:1991-01-01 00:00:00

  • [Problems in the selection of surgical approach for the treatment of non-traumatic deformities of the craniocervical junction].

    abstract::Developmental abnormalities or inflammatory disorders provoke deformations and instability of the craniocervical junction. The most dangerous results of these lesions are: sudden brainstem compression or cervical myelopathy. The authors propose the guidelines for surgical management of non-traumatic deformities caused...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Radek A,Zapałowicz K,Maciejczak A,Karbownik J,Grochal M,Radek M,Błaszczyk B,Skiba P

    更新日期:2002-03-01 00:00:00

  • [Progressive spinal muscular atrophy of proximal location in adults].

    abstract::The authors report two cases of familial progressive muscular atrophy of proximal localization, with late onset of signs which was associated with involvement of the motor nucleus of trigeminal nerve and hypoglossus nerve nucleus as well as with presence of gynaecomastia. Cases of coexistence of gynaecomastia with spi...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Bitner-Manicka M,Szmidt E

    更新日期:1976-07-01 00:00:00

  • [Treatment of Guillain-Barré syndrome by the method of fractionated plasma exchange with controlled hemodilution].

    abstract::Plasma exchange under controlled haemodilution was tried in 9 patients with Guillain-Barré syndrome repeating the procedure at 24-hour intervals for from 7 to 17 times with a total exchange of plasma ranging from 2.0 to 4.9 litres. All patients had significant paresis or paralysis of all four extremities, and 3 had ad...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Kazibutowska Z,Antoszewski Z,Włodarski M,Stolarzewicz-Zajac K

    更新日期:1985-09-01 00:00:00

  • [Evaluation of the accessibility of stroke units in Poland].

    abstract:BACKGROUND AND PURPOSE:According to the World Health Organization (WHO) assumptions every patient with a stroke should be treated by a specialized stroke team or in a specialized stroke unit. The aim of our study was to evaluate the accessibility and eligibility of stroke units in Poland. MATERIALS AND METHODS:We have...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Członkowska A,Sarzyńska-Długosz I,Niewada M,Kabayashi A,Ryglewicz D

    更新日期:2004-09-01 00:00:00

  • [Importance of intensive therapy in the treatment of severe craniocerebral trauma].

    abstract::During 10 years 15 085 patients were treated at the surgical department of the County Hospital in Wyszków including 415 cases of severe craniocerebral injury (2.7%). The author stressed and justifies the necessity of organization of intensive therapy and resuscitation units at the admission rooms of county hospitals f...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Pietrak A

    更新日期:1975-05-01 00:00:00

  • [Migraine--considerations on the achievements in medicine].

    abstract::Migraine is among the most mysterious diseases. It has been known for centuries but as yet it has resisted the advances in medicine and has not revealed its aetiology, mechanism of headache and possibilities of treatment. Various theories on the pathogenesis of migraine and arguments for and against them are reviewed ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Domzał T

    更新日期:1992-01-01 00:00:00

  • [Prognostic significance of early CT changes in ischemic stroke patients].

    abstract::The aim of the study was to establish the prognostic value of early CT findings in predicting the 30-day mortality after stroke, to assess the prevalence of these findings in acute stroke patients, and to examine the correlation between these findings and the clinical status. 134 patients (mean age 67.5 +/- 12.1) with...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Szczudlik A,Zwolińska G,Słowik A,Turaj W,Pera J,Urbanik A,Uhl H

    更新日期:2001-07-01 00:00:00

  • Nucleus accumbens stimulation in pathological obesity.

    abstract::One of the potential treatment methods of obesity is deep brain stimulation (DBS) of nucleus accumbens. We describe the case of 19 years old woman with hypothalamic obesity. She weighted 151.4 kg before DBS and the non-surgical methods proved to be inefficient. She was treated with implantation of DBS electrode to nuc...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2016.01.014

    authors: Harat M,Rudaś M,Zieliński P,Birska J,Sokal P

    更新日期:2016-01-01 00:00:00

  • [Klein-Levin syndrome (case report)].

    abstract::The authors observed the syndrome in a 17-year-old boy weighing 86 kg and training weight-lifting. During between 10 and 20 months he had periods of physiological sleep lasting on the average 7 days, with voracious appetite and dysphoris. In the EEG tracings corresponding to physiological sleep were observed during th...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Nowak S,Błaszczyk B

    更新日期:1984-03-01 00:00:00

  • [Our method of creating experimental aneurysms and its use in the training in microsurgical operations].

    abstract::An original method is presented used for production of experimental aneurysms in rats. The method may be useful in training for microneurosurgical treatment of aneurysms. ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Ciszek B,Zabek M,Górski R

    更新日期:1992-01-01 00:00:00

  • Strategy for the surgical treatment of vestibular schwannomas in patients with neurofibromatosis type 2.

    abstract:OBJECTIVE:Guidelines for appropriate management of vestibular schwannomas in NF2 patients are controversial. In this paper we reviewed our experience with patients with NF2 for the results of surgical treatment with particular reference to hearing and facial nerve preservation. METHODS:We included in the study 30 pati...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2015.06.008

    authors: Nowak A,Dziedzic T,Czernicki T,Kunert P,Morawski K,Niemczyk K,Marchel A

    更新日期:2015-01-01 00:00:00

  • [Visual and somatosensory evoked potentials in the patients with non-Hodgkin lymphoma].

    abstract::Visual (VEPs) and somatosensory (SEPs) evoked potentials in a group of 33 patients (mean age 49 years) with non-Hodgkin lymphoma (n-HL) without CNS involvement were recorded. There were 24% of patients with pathological VEPs and 30% of patients with pathological SEPs. Pathological VEPs and SEPs were both recorded in 4...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Ejma M,Bieszczad M,Podemski R,Bilińska M,Usnarska-Zubkiewicz L

    更新日期:1995-05-01 00:00:00

  • [Subarachnoid hemorrhage due to conus medullaris ependymoma].

    abstract::A case of conus medullaris tumour (ependymoma) is reported in which the presenting symptom was subarachnoid haemorrhage, which has left bladder dysfunction. 70-year-old patient was admitted to the Department of Neurology due to symptoms of conus medullaris lesion with retention of urine and diminished pain sensitivity...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Janda R,Bolewski J,Dabek A,Tutaj A

    更新日期:1998-03-01 00:00:00

  • The use of functional magnetic resonance imaging in reducing a risk of postoperative neurological deficits in the patients with brain tumour.

    abstract:BACKGROUND AND PURPOSE:The purpose of the study was to compare the results of operative treatment of tumours located in the sensory-motor cortex guided with functional magnetic resonance imaging (fMRI) combined with the neuro-na-vigation system to the results of classical operative treatment. MATERIAL AND METHODS:The ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.5114/ninp.2013.39072

    authors: Tymowski M,Majchrzak K,Bobek-Billewicz B,Ladziński P,Majchrzak H

    更新日期:2013-11-01 00:00:00

  • [Disorders and difficulties in the psychosocial adaptation of epileptics].

    abstract::Disturbances of and difficulties in psychosocial adaptation were analysed in 63 epileptics (with generalized convulsions and partial complex seizures) and in 31 subjects without diseases of the central nervous system (control group). The disturbances of adaptation were not more frequent in epileptics than in controls....

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Florek M,Jagiello H,Wygnańska B,Bittner-Manicka M

    更新日期:1980-01-01 00:00:00

  • [Physical therapy in peripheral facial paresis].

    abstract::Peripheral facial paresis is a serious clinical and social problem. The effect of physical therapy in 44 patients aged 13-80 was studied. Idiopathic peripheral facial paresis was the cause of mimic muscles dysfunction in 75% of our patients. Medical treatment was conducted according to the established program, consist...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Zgorzalewicz M,Łaksa B

    更新日期:2001-01-01 00:00:00

  • [Lyme disease in children].

    abstract::In the recent years the number of diagnosed cases of Lyme Disease has tended to increase. This is due to the possibility of serological examinations. Between 1992-95 at the Neurological Department of 2nd Chair of Pediatrics Silesian Medical Academy in Katowice 7 children with Lyme Disease were hospitalized. The author...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Marszał E,Wojaczyńska-Stanek K,Szwed-Białozyt B,Jamroz E

    更新日期:1998-05-01 00:00:00

  • [Certain clinical and epidemiological problems of reversible ischemic neurological deficit].

    abstract::The studied material comprised 280 patients hospitalized for the first time for reversible ischaemic neurological deficit. The clinical condition of the patients, the incidence of hypertension (48.3%), ischaemic heart disease (36.4%) and diabetes (4.3%) was assessed and the indices were calculated of first admissions ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Piórek TM

    更新日期:1996-09-01 00:00:00

  • Improvement of quality of life after therapeutic plasma exchange in patients with myasthenic crisis.

    abstract:INTRODUCTION:We sought to evaluate quality of life patients with myasthenic crisis before and after therapeutic plasma exchange. MATERIALS AND METHODS:In our study we conducted an assessment of the quality of life with the use of the questionnaire SF-36, when executed eleven therapeutic plasma exchange. The assessment...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2016.07.005

    authors: Rozmilowska I,Adamczyk-Sowa M,Rutkowska K,Pierzchala K,Misiolek H

    更新日期:2016-01-01 00:00:00

  • [Treatment of multiple sclerosis with cladribine (2-CDA), a new immunosuppressant agent. Theoretical basis and preliminary results].

    abstract::The rationale for immunosuppressive treatment of multiple sclerosis comes from current concepts of pathogenesis of this disease. However, clinical effects of immunosuppression have been largely disappointing. Cladribine (chloro-2'-deoxyadenosine, 2CdA) is a new antileukaemic drug which also shows a strong immunosuppre...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Grieb P,Stelmasiak Z

    更新日期:1995-01-01 00:00:00

  • [Evaluation of treatment efficiency of acute hemispheric strokes using intravenous nimodipine infusions].

    abstract::The authors present the results of treating acute hemispheric stroke with intravenous nimodipine. 17 patients were additionally treated with nimodipine given intravenously in 1 mg-2 mg dose, and the control group consisted of 71 patients treated in standard way with Dextran 40,000. The selection of patients for the st...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Szczechowski L,Wajgt A

    更新日期:1994-05-01 00:00:00

  • ["Malignant" middle cerebral artery territory infarction].

    abstract::The pathology, clinical course, outcome, diagnosis, treatment and prognosis of dramatic malignant middle cerebral artery territory infarction were presented. About 10% of stroke patients suffer from malignant middle cerebral artery territory infarction, mainly due to brain edema and herniation. This syndrome causes hi...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Mendel T

    更新日期:2005-09-01 00:00:00

  • [Development of grasping and manipulatory function in the paretic hand in hemiparetic children].

    abstract::In the light of observation of 60 children aged from 4 months to 8 years followed for 4--6 years the author studied the stages of functional development of the paretic hand in hemiparesis in infantile cerebral palsy. It is concluded that the development of the functions of grasping and manipulation is retarded and dis...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Molczanow A

    更新日期:1977-09-01 00:00:00

  • [Physiological basis and clinical relevance of brain temperature control].

    abstract::It has been recently shown that small variations in cerebral temperature critically determine the extent of neurological damage following an ischaemic insult. These reports spurred a new interest in brain temperature among clinicians--neurologists and neurosurgeons. The information about this subject is very sparse an...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Mariak Z

    更新日期:1994-07-01 00:00:00

  • [Direct fixation of the odontoid fracture in a child].

    abstract::The use of spinal implants in the pediatric population is controversial in terms of skeletal immaturity. The authors present the case of a 12-year-old boy with displaced Type III odontoid fracture, successfully treated by direct screw fixation. Fractures defined as Type II and Type III according to the classification ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Zapałowicz K,Radek M,Radek A

    更新日期:2004-07-01 00:00:00

  • [Diagnostic value of 24-hour simultaneous EEG and ECG monitoring of patients with heart diseases and atypical consciousness disorders].

    abstract::In 24 patients with diagnostically not clear, short, recurrent episodes of consciousness disturbances and heart diseases and/or a history of arrhythmia simultaneous 24-hour recording was done of eeg and ecg. In the differential diagnosis epilepsy was considered, especially since in most cases routine eeg records demon...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Niedzielska K,Laskowska-Studniarska W,Kunicka J,Popławska W,Kuran W,Witkowska-Olearska K

    更新日期:1992-07-01 00:00:00

  • [The usefulness of neurological and radiological signs in lumbar discopathy].

    abstract::The aim of the work was to show the usefulness of neurological and radiological signs in the patients with L4 and L5 discopathy. The axial symptoms with the highest occurrence frequency and the differential symptoms closely connected with definite disc pathology: the type and/or the level of discopathy were defined. T...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Sobolewski P

    更新日期:1998-05-01 00:00:00

  • [Prognostic significance of transient hyperglycemia in acute phase of ischemic stroke].

    abstract::Experimental studies of different stroke models equivocally showed that hyperglycaemia is responsible for the increase of infarct volume and mortality. Similar results were obtained in several, but not all clinical studies. The aim of the study was to assess the occurrence and prognosis of transient hyperglycaemia in ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Słowik A,Zwolińska G,Tomik B,Wyrwicz-Petkow U,Szczudlik A

    更新日期:1998-03-01 00:00:00

  • Clinical features and risk factors of angiography headache and evaluation of its relationship to primary headaches - an important but neglected problem.

    abstract:INTRODUCTION:The authors of the article published in the current edition a single-centre prospective cohort study featuring patients who had undergone a diagnostic cerebral angiography procedure and who had experienced a headache associated with the procedure [1]. The authors of 'Clinical features and risk factors of a...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.5603/PJNNS.a2019.0057

    authors: Domitrz I

    更新日期:2019-01-01 00:00:00