Abstract:
:Current classification of primary progressive aphasia (PPA) encompasses three variants: non-fluent (nfvPPA), semantic (svPPA) and logopenic (lvPPA). Previously lvPPA was regarded as aphasic form of Alzheimer's disease (AD). However, not all patients with lvPPA phenotype present with AD pathology. Despite abundant literature on differentiation of lvPPA from svPPA and nfvPPA, studies comparing lvPPA with AD and mild cognitive impairment (MCI) are scarce. This study aimed at analyzing written descriptive output in lvPPA, AD and MCI. Thirty-five patients participated in the study: 9 with lvPPA, 13 with AD and 13 with MCI. Most aspects of writing performance were comparable in three groups. However, letter insertion errors appeared in 44% patients with lvPPA, while they were absent in AD and MCI. Patients with lvPPA used more verbs than patients with AD. Writing profile may complement other neuropsychological assessment results in the differential diagnosis of lvPPA. Letter insertion errors and frequent verb use may raise a query of lvPPA.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Sitek EJ,Barczak A,Kluj-Kozłowska K,Kozłowski M,Barcikowska M,Sławek Jdoi
10.1016/j.pjnns.2015.06.001subject
Has Abstractpub_date
2015-01-01 00:00:00pages
239-44issue
4eissn
0028-3843issn
1897-4260pii
S0028-3843(15)00092-4journal_volume
49pub_type
杂志文章abstract::A group of 50 epileptics (group C) with frequent seizures refractory to treatment was studied. The control group (R) comprised 50 cases with rare seizures. It was found that despite systematic treatment (with full therapeutic doses) and frequent changes of drugs the frequency of seizures was not reduced in group C. Th...
journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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journal_title:Neurologia i neurochirurgia polska
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