Abstract：
:The author reviews two decades of clinical research directed towards the links between disturbances of the oculomotor functions and the severity and progress of Alzheimer's disease. Two basically different streams of research are identified. The first based on precise, quantitative examination of automatic or reflexive eye movements, including saccadic refixation and smooth pursuit. Using both predictable and random changes of the stimuli parameters, researchers have isolated the oculomotor functions of prediction and planning that relate to more advanced processing compared to the simple stimulus-driven responses. Disorders of the smooth eye movement control and of saccadic refixation have been used for quantifying the motor dysfunction in Alzheimer's disease. The second stream of research has been targeted on more cognitive components and their expression in visual interactions with the surroundings, with subjects exposed to deliberated modified visual environments, that would normally evoke curiosity and emotional responses, and modulate awareness.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Przedpelska-Ober Esubject
Has Abstractpub_date
2006-01-01 00:00:00pages
34-41issue
1eissn
0028-3843issn
1897-4260pii
5458journal_volume
40pub_type
杂志文章,评审abstract：:The rationale for immunosuppressive treatment of multiple sclerosis comes from current concepts of pathogenesis of this disease. However, clinical effects of immunosuppression have been largely disappointing. Cladribine (chloro-2'-deoxyadenosine, 2CdA) is a new antileukaemic drug which also shows a strong immunosuppre...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:The authors describe two cases of extramedullary tumours in the vertebral canal with long (7 and 15 years) course without pains and with clinical manifestations simulating Charcot-Marie-Tooth disease. It is stressed in conclusion that sporadic cases of this disease with involvement of the lower extremities only, with ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Metachromatic leukodystrophy is a genetic metabolic disease which generally occurs in childhood, surprisingly it can also occur during adulthood. Adult forms have very often characteristic presentations with progressive dementia. The authors presented a case of metachromatic leukodystrophy in an adult, differential di...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Endocarditis is an infectious and inflammatory disease of cardiac valves with other coexisting symptoms affecting heart and other organs and systems. Patients with cardiac valves diseases are in the group of high risk. The authors present a case of successfully treated endocarditis affecting mitral valve prosthesis in...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:In a group of 15 patients with multiple sclerosis and in a control group of 20 healthy subjects visual evoked potentials produced with flashes or checkerboard pattern, auditory evoked potentials after stimulation with three different tones, and somatosensory evoked potentials after stimulation of the left, right or bo...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:Conventional methods of neuroimaging, such as computed tomography and magnetic resonance imaging, are mostly useful in exclusion of movement disorders with secondary aetiology. Recently, the application of transcranial sonography has been introduced to the diagnosis of extrapyramidal diseases. This valuable technique,...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/s0028-3843(14)60155-9
更新日期：2010-11-01 00:00:00
abstract：:In an experimental model the effect of increased intracranial pressure on respiration and circulation was studied. Infusions of varying volumes of fluid into the subarachnoid space over the convexity of the brain in the right parietal area were carried out, recording then changes in respiration and arterial blood pres...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:The authors present a case of a 36 years old woman with systemic sclerosis and multiple cerebral aneurysms. A higher operative risk in patients with systemic diseases is discussed. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:The problem of pathogenesis and effective treatment of traumatic optic neuropathy (TON) is still an open question. According to current opinions the immediate results of conservative treatment with megadose corticosteroids are similar to those obtained with surgical decompression. No data on late results of both modes...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：BACKGROUND:Sex and blood level of sex hormones play a key role not only in the susceptibility to develop Parkinson's disease (PD) but also influence the natural course of the disease. The aim of this study was to compare reproductive lifespan events in females affected with PD and in "non-parkinsonian" age matched subj...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2014.08.004
更新日期：2014-01-01 00:00:00
abstract：:Tiagabine (TGB) is a novel anti-epileptic drug providing new therapeutic possibilities to patients with focal seizures resistant to treatment. Since there is no clear algorithm for the best add-on therapy, the aim of our work was to establish factors that statistically significantly affect tiagabine efficacy and toxic...
journal_title：Neurologia i neurochirurgia polska
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：2003-05-01 00:00:00
abstract：:The authors report a case of conservatively cured abscess in the left cerebellar hemisphere demonstrated by CT. The patient was admitted in serious condition to a neurotraumatology centre. After pharmacological treatment a quick improvement of patient's health was achieved and control CT examination during his stay in...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Out of over 100 children with the Lennox-Gastaut syndrome observed in the Outpatient Clinic and Department of Paediatric Neurology, Children's Health Center the authors present 6 cases in which the course of the disease was progressive and devastating. The main signs were astatic-myoclonic and generalized seizures, re...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Patients suffering from Huntington disease (HD) have been shown to present with poor self-awareness of a variety of symptoms. The study aimed to assess the self-awareness of memory impairment in HD in comparison to advanced Parkinson disease (PD), mild PD and cervical dystonia. MATERIAL AND METH...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.30262
更新日期：2012-07-01 00:00:00
abstract：:Intracranial pressure (ICP) pulse wave was analysed during infusion tests performed in hospital (hydrocephalus) and in cats. Pulse wave changes were evaluated calculating the high frequency centroid index (HFC) in the HFC, found to be a very valuable parameter in intracranial volume-pressure situation evaluation. The ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The purpose of the study was an attempt at evaluation of therapeutic results in 10 cases of tumours situated in the pineal region. The diagnosis was based on clinical and neuroradiological findings. Treatment included neurosurgical decompressing procedures (by the methods of Torkildsen, Pudenz Stookey-Scarf) followed ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
abstract：:Numerous factors are involved in the pathogenesis of Parkinson's disease, including inflammation in certain regions of the brain. Studies suggest a significant role of microglia in dopaminergic cell injury. Cytokines and apoptosis-related proteins were elevated in the brain and cerebrospinal fluid. The occurrence of a...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:The occurrence of intracranial haemorrhage, epileptic seizures and focal neurological signs was estimated in the group of 40 patients with AVMs. Size of AVM, its localization was established by angiography. Maximum diameter of a haematoma was measured on preoperative CT. We found that small AVMs (diameter < 3 cm) are ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Hydatid disease caused by Echinococcus granulosus and Echinococcus multilocularis commonly presents with pulmonary and hepatic cysts. Primary paraspinal muscle cysts are a rare presentation. We report a case of hydatid cyst within paraspinal muscles presenting with cervical mass and associated pain. The hydatid diseas...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/s0028-3843(14)60110-9
更新日期：2011-07-01 00:00:00
abstract：:14 patients with Tick-borne Encephalitis (TBE) aged 21-64 (mean = 42.3) were analysed. The activity of superoxide dismutase (SOD), glutathione reductase (GSSG-R), glutathione peroxidase (GSH-Px), concentrations of malondialdehyde (MDA) and total sulphydryl groups (-SH) were measured in cerebrospinal fluid (CSF). Contr...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：:During a 3-year period of treatment with DPH three episodes of drug intolerance developed in a 16-year-old epileptic girl. The dose tolerated previously was 200 mg daily. The authors stress the effect of hormonal disturbances on the change in DPH tolerance. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Benign spinal neoplasm (b.s.n.) represented 11% (8 cases) of all histopathologically verified spinal neoplasm in 85 patients operated on between 1975 and 1990. Local back or neck pain were first clinical symptoms of b.s.n. On admission all the patients presented with bone lesions on X-ray plain radiograms of the spine...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：:Authors discuss the possible etiopathogenesis of Reye syndrome (RS) on the base of eight own cases presented in this paper and others previously described. The febrile infection was observed on the beginning of the disease in all actually analysed cases and was followed by symptoms of acute damage of liver and brain. ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:In the light of observation of 60 children aged from 4 months to 8 years followed for 4--6 years the author studied the stages of functional development of the paretic hand in hemiparesis in infantile cerebral palsy. It is concluded that the development of the functions of grasping and manipulation is retarded and dis...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:A group of 69 patients aged 60-80 years with brain tumours were analysed, estimating the surgical risk at the time of qualification for operations. Surgical treatment was given to 36 patients limiting it to lobectomy of the part of the brain containing the greater part of the tumour. The peri-operational mortality was...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:The following article presents current views on the possibility of pharmacological treatment of Parkinson's disease (PD). Research conducted on drugs with potentially neuroprotective effects has changed the way we viewed the treatment of early stages of PD. Beginning treatment with the application of dopamine agonists...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-05-01 00:00:00
abstract：:Discontinuation of fingolimod in patients with multiple sclerosis (MS) can lead to disease reactivation. In this review, we describe cases of severe exacerbations in patients with MS following discontinuation of fingolimod, including three cases from our center. We consider potential mechanisms of disease reactivation...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/j.pjnns.2017.01.006
更新日期：2017-01-01 00:00:00
abstract：:The authors describe a case of CJD in a man aged 45 years. The disease began with sluggishness of movements and speech difficulties, followed by development of pyramidal system damage and dementia. EEG findings were normal throughout the whole duration of the disease that is 3.5 years. Neuropathological examination di...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:The blood serotonin level was determined by the fluorescent method of Ashcroft in 13 patients with sciatic pains during the pains and after the disappearance. The serotonin level was usually higher at the time of pains. In the discussion the author reminds that serotonin level falls during a migrainous attack and poin...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:There is an increasing appreciation that multiple sclerosis (MS) can affect children. Up to 10% of MS patients experience their first symptoms before the age of 16. The natural history and magnetic resonance imaging of MS in child-hood differ from those observed in adult patients. The differential diagnosis of MS in c...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/s0028-3843(14)60027-x
更新日期：2011-03-01 00:00:00
