Abstract：
BACKGROUND AND PURPOSE:Patients suffering from Huntington disease (HD) have been shown to present with poor self-awareness of a variety of symptoms. The study aimed to assess the self-awareness of memory impairment in HD in comparison to advanced Parkinson disease (PD), mild PD and cervical dystonia. MATERIAL AND METHODS:Self-awareness was tested in 23 patients with HD by comparing patient and caregiver ratings in reference to clinical control groups (25 patients with advanced PD, 21 with mild PD and 20 with cervical dystonia). Self-awareness was tested using the Self Rating Scale of Memory Functions, which was administered to both the patients and the caregivers. Neuropsychological assessment addressed general cognitive status (Mini-Mental State Examination), verbal learning (Auditory Verbal Learning Test, 15-word list) and mood (Montgomery-Asberg Depression Rating Scale). RESULTS:Patients with HD significantly underestimated their memory dysfunction. Underestimation of memory deficit correlated with disease duration and disease severity in HD. CONCLUSIONS:Huntington disease patients underestimate memory dysfunction. These results add to the previous reports on poor insight in HD in other domains and suggest that anosognosia in HD, albeit usually rather mild, may be a generalized phenomenon.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Sitek EJ,Sołtan W,Robowski P,Schinwelski M,Wieczorek D,Sławek Jdoi
10.5114/ninp.2012.30262subject
Has Abstractpub_date
2012-07-01 00:00:00pages
318-25issue
4eissn
0028-3843issn
1897-4260pii
S0028-3843(14)60447-3journal_volume
46pub_type
杂志文章abstract：BACKGROUND AND PURPOSE:Migraine is a common neurologic disorder whose etiology remains unknown. Migraine has been reported as a possible risk factor for ischemic stroke, especially in young women. The relationship between migraine and stroke is stronger in patients suffering from migraine with aura compared to those wi...
journal_title：Neurologia i neurochirurgia polska
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abstract：BACKGROUND:The epilepsy treatment during pregnancy represents a balance between teratogenic hazard and seizure control. The aim of the study was to evaluate the safety and efficacy of lacosamide (LCS) during pregnancy and breastfeeding. METHODS:Patients referred to our Epilepsy Center for pregnancy planning who became...
journal_title：Neurologia i neurochirurgia polska
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abstract：:Deep brain stimulation (DBS) of the ventral intermediate thalamic nucleus (Vim) has been recently introduced by Benabid and his colleagues as a new surgical procedure in the treatment of tremor-dominant Parkinson's disease (PD). The advantage of DBS Vim over lesioning (thalamotomy) is its reversibility and adjustabili...
journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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doi：
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
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journal_title：Neurologia i neurochirurgia polska
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doi：
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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doi：
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
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