Abstract：
:14 patients with Tick-borne Encephalitis (TBE) aged 21-64 (mean = 42.3) were analysed. The activity of superoxide dismutase (SOD), glutathione reductase (GSSG-R), glutathione peroxidase (GSH-Px), concentrations of malondialdehyde (MDA) and total sulphydryl groups (-SH) were measured in cerebrospinal fluid (CSF). Control group consisted of 10 patients whose CSF parameters remained in normal range. The CSF examination was performed twice: before and 3 weeks after treatment. The analysed activity of SOD, GSH-Px, GSSG-R, MDA and total sulphydryl groups (-SH) during the acute stage of the disease was significantly lower comparing to the control group. Despite the treatment, GSSG-R activity, MDA concentration and total sulphydryl groups--SH further lowered significantly. Although the SOD activity in CSF was higher in the second examination, it remained significantly lower comparing to the control group. We showed that the GSH-Px and GSSG-R activity in CSF after the acute stage of the TBE remained significantly lower than in the control group. Our examinations prove that during the TBE an increased generation of oxygen-derived free radicals occurs what shows decreased activity of the antioxidant parameters (SOD, GSH-Px, GSSG-R) and decreased concentration of total sulphydryl groups--SH in CSF. Our results suggest that during TBE, molecular structures injury of enzymes and antioxidative reactive cofactors may occur.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Pancewicz SA,Hermanowska-Szpakowicz T,Makarewicz-Płońska M,Witek A,Farbiszewski R,Zajkowska J,Michalska Bsubject
Has Abstractpub_date
2002-07-01 00:00:00pages
767-76issue
4eissn
0028-3843issn
1897-4260journal_volume
36pub_type
杂志文章abstract：:The authors report a case of sporadic secondary amyloidosis with polyneuropathy in a patient aged 50 years. The disease developed during chronic pyelonephritis. The case is described in view of its rare occurrence, diagnostic difficulties and interesting histological findings. ...
journal_title：Neurologia i neurochirurgia polska
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更新日期：1977-01-01 00:00:00
abstract：:The authors report the case of an exceptional presentation of vertebral artery dissection. A 44-year-old man who presented with left shoulder weakness, radicular pain and numbness of the left forearm and thumb was admitted to our hospital with an initial diagnosis of cervical disc herniation. Due to the inconsistency ...
journal_title：Neurologia i neurochirurgia polska
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abstract：:Autosomal-dominant polycystic kidney disease (ADPKD) is a relatively frequent genetic disorder that is associated with increased prevalence of intracranial aneurysms (IAs). However, evidence on the natural history of IAs in ADPKD is suboptimal. That leads to difficulties in development of recommendations on surveillan...
journal_title：Neurologia i neurochirurgia polska
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doi：10.1016/j.pjnns.2017.08.007
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abstract：:Disturbances of glucose metabolism in epilepsy and other neurodegenerative diseases. Impairment of glucose and acetyl-CoA metabolism is a characteristic feature of several degenerative brain diseases. Presented paper provides experimental evidences that NO, aluminum and thiamine deficiency result in concordant disturb...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
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abstract：:The authors describe 32 cases of hydrocephalus of different aetiology in which the effectiveness of the ventriculoatrial shunt was evaluated by means of repeated computerized axial tomographic (CT) investigations. This investigation made it possible to demonstrate in a way not exposing the patients to any complication...
journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1981-01-01 00:00:00
abstract：:In the years 1965-1990 in the hospital department for treatment of spinal injuries 1330 patients with spinal lesions at the C5-Th1 levels were treated after admission early after trauma. The most frequent causes of injuries of this part of the spine were falls from horsecarts, jumping into water head first and traffic...
journal_title：Neurologia i neurochirurgia polska
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abstract：BACKGROUND AND PURPOSE:Synovial cysts of the spine occur most frequently in the lumbosacral region. Methods of treatment vary, but in cases of chronic pain or neurological deficits surgical intervention is undertaken. The aim of this paper is to present indications, surgical technique and efficacy of surgical treatment...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.31356
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abstract：OBJECTIVE:Vertebral artery medulla compression syndrome (VAMCS) is a very rare condition manifesting as different neurological focal deficits. The case of a 36-year-old male with symptomatic brainstem compression by vertebral artery (VA) treated by means of microvascular decompression (MVD) and a review of the literatu...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2018.03.005
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：2004-05-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：2007-03-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：2000-05-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1984-03-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.1016/s0028-3843(14)60110-9
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：2001-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1983-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1987-11-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1998-09-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1998-11-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：2007-09-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1995-09-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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更新日期：1979-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：10.1016/j.pjnns.2014.09.009
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journal_title：Neurologia i neurochirurgia polska
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更新日期：1992-09-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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abstract：:The authors present a case of Huntington disease in a 14 year old boy. The basis of genetic, pathoetiology, clinical course of disease, significance of molecular analysis of DNA are discussed. ...
journal_title：Neurologia i neurochirurgia polska
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更新日期：1998-07-01 00:00:00
