[Role of gamma-delta T-cells and heat shock proteins in immunological response and in pathogenesis of neurological diseases].

Abstract:

:T cells with gamma delta receptor form small percentage of lymphocytes in healthy individuals, whereas their number increases in persons with immunological disorders. Heat shock proteins (HSPs), which play a central role in protein transformation, could be antigens for gamma delta T cells. HSPs participate in mutual interactions of gamma delta cells and tissue cells, taking part in defense mechanism against infection and auto destruction. There is an interest' in the HSPs' role in modulation of both normal and pathological activity within the nervous system. HSPs can protect cells against undesired stimulation, probably by long-term protein expression. Results of the studies suggest participation of gamma delta T cells and HSPs in pathogenesis of certain diseases, including neurological ones (multiple sclerosis, Alzheimer's disease, Parkinson's disease and cerebrovascular diseases), although detailed explanation of this problem requires further studies.

journal_name

Neurol Neurochir Pol

authors

Fiszer U

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

737-45

issue

5

eissn

0028-3843

issn

1897-4260

journal_volume

29

pub_type

杂志文章,评审
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  • [Gunshot wounds of the spine and spinal cord. Neurosurgical tactics].

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    authors: Jarmundowicz W,Radek A

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  • [Case of spontaneous intracerebral hematoma with subsequent development of post-hemorrhagic cyst].

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    authors: Marlicz M,Szecherew G,Bukowski J

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  • [Spontaneous hemorrhage in brain tumors].

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    authors: Bromowicz J

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  • [A rare case of intracranial hematoma complicating bacterial endocarditis].

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    authors: Michalska-Krzanowska G,Dybkowska K,Badowicz B

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  • [A case of Behcet's syndrome].

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    authors: Maślanka S

    更新日期:1985-01-01 00:00:00

  • [Comparison of results of polygraphic sleep studies and cerebrospinal fluid pressure records in patients following removal of supratentorial expanding lesions].

    abstract::In 4 patients operated upon for supratentorial brain tumors the authors carried out on the 3rd day after the operation polygraphic recording of nocturnal sleep with simultaneous measurements of cerebrospinal fluid pressure in the ventricular system by the method of Lundberg. A comparison of polygraphic records of noct...

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    doi:

    authors: Darwaj B,Moszyński K,Koźniewska H,Czochra T,Smyk K

    更新日期:1977-09-01 00:00:00

  • The importance of atrial fibrillation and selected echocardiographic parameters for the effectiveness and safety of thrombolytic therapy in patients with stroke.

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  • [The physiopathology of acute spinal cord injury and a hope for a successful treatment].

    abstract::The acute phase of spinal cord injury includes primary and secondary pathological patterns. Primary patterns include the effects of contusion, laceration, stretch of neural tissue and direct vascular trauma. These changes are irreversible. Secondary patterns include posttraumatic ischemic changes, loss of energy metab...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Harat M,Radek A,Kochanowski J

    更新日期:1996-01-01 00:00:00

  • Falcotentorial and velum interpositum meningiomas: two distinct entities of the pineal region.

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  • [Diagnostic problems in vertebral body hemangioma].

    abstract::Vertebral haemangioma is a slowly growing benign tumour arising from blood vessels. Haemangioma of the vertebrae is usually asymptomatic. Neurological symptoms occur when haemangioma causes compression of nerve roots or spinal cord. In this paper a case of a 59 year-old woman with, vertebral body L2 haemangioma is rep...

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    doi:

    authors: Bobek J,Wilk L

    更新日期:1999-03-01 00:00:00

  • [Direct effects of the intrathecal administration of normal saline for the brain expansion after the removal of subdural hematoma].

    abstract::In a group of 360 patients the effects were studied of various management methods in case of lacking expansion of the brain after removal of chronic subdural haematoma on the therapeutic results. It was found that intrathecal infusion of normal saline was an effective procedure, with small frequency of transient compl...

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    pub_type: 杂志文章

    doi:

    authors: Zderkiewicz E,Janusz W,Czochra M,Trojanowski T,Kaczmarczyk R,Osuchowski J,Chmielewska A,Mitosek-Sabbo D,Szczepanek D

    更新日期:1996-05-01 00:00:00

  • [History of discoveries and advances in the studies of parkinsonism].

    abstract::A review is presented of the more important discoveries and advances in the 175-year history of the studies and therapeutic trials on parkinsonism. The personality and achievements of James Parkinson are described, with a brief discussion on his most important paper "An Essay on Shaking Palsy". The important works of ...

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    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Kuran W

    更新日期:1992-07-01 00:00:00

  • A patient with acute aortic dissection presenting with bilateral stroke - A rare experience.

    abstract::Acute aortic dissection is a rare, life-threatening condition requiring early recognition and proper treatment. Although chest pain remains the most frequent initial symptom, clinical manifestation of aortic dissection varies. Rarely aortic dissection starts with neurological symptoms such as ischemic stroke, which is...

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  • [Parkinsonism following lethargic encephalitis].

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  • Validation analysis of the Polish version of the Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL).

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  • [Whipple's disease--a rare cause of neurological symptoms and disorders].

    abstract::Whipple's disease is a chronic infection caused by Gram-positive bacillus Thropheryma Whippelii picture with a wide range of clinical manifestation, not only systemic but also neurological. Seronegative arthritis or arthralgia may be the only presenting symptom, predating by years gastrointestinal, and also pulmonary,...

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    authors: Słowik A,Szczudlik A

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  • Significance of aneurysm wall enhancement on high-resolution vessel wall magnetic resonance imaging in clinical management of patients with intracranial aneurysms.

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  • [Involuntary movements as a complication of treatment of extrapyramidal disorders with L-dopa].

    abstract::The frequency of dyskinesias connected with L-DOPA treatment of certain extrapyramidal system diseases was studied. Among 111 studied patients with Parkinson's disease drug-induced dyskinesias were observed in 56 cases (that is 50% of the treated patients) while in the group of other extrapyramidal system diseases (to...

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    authors: Friedman A,Markowa E

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  • [Hydrocortisone in the treatment of painful syndromes of the cervical spine].

    abstract::The authors used hydrocortisone POLFA injecting it paravertebrally in painful syndromes of the cervical spine. The clinical material comprised 50 patients divided into groups A and B of 25 patients each. In both groups typical anti-inflammatory and analgesic agents and muscle relaxants were given and physiotherapy was...

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    authors: Eljasz L,Krazysztoń-Przekop T

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  • [Simultaneous measurement of conduction velocity in the neural sensory and motor fibers during segmental stimulation].

    abstract::The study concerned the method of investigation of upper extremity nerves which makes possible a simultaneous measurement of the conduction velocity in the motor and sensory fibres over the whole length of the nerve. Recording of responses was based on the use of surface electrodes which are safe, less painful for the...

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    authors: Kopeć J

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  • Is descriptive writing useful in the differential diagnosis of logopenic variant of primary progressive aphasia, Alzheimer's disease and mild cognitive impairment?

    abstract::Current classification of primary progressive aphasia (PPA) encompasses three variants: non-fluent (nfvPPA), semantic (svPPA) and logopenic (lvPPA). Previously lvPPA was regarded as aphasic form of Alzheimer's disease (AD). However, not all patients with lvPPA phenotype present with AD pathology. Despite abundant lite...

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  • [Problems in the selection of surgical approach for the treatment of non-traumatic deformities of the craniocervical junction].

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  • [Migraine--considerations on the achievements in medicine].

    abstract::Migraine is among the most mysterious diseases. It has been known for centuries but as yet it has resisted the advances in medicine and has not revealed its aetiology, mechanism of headache and possibilities of treatment. Various theories on the pathogenesis of migraine and arguments for and against them are reviewed ...

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    authors: Domzał T

    更新日期:1992-01-01 00:00:00

  • [Dynamic assessment of blood flow in pre-cranial and intracranial arteries in patients with mild head injuries].

    abstract::Mild head injury constitutes about 75% of all head injury cases. The post-concussion syndrome usually following a mild head injury is connected with numerous symptoms and not very severe signs. Research findings indicate that the symptoms related to mild head injuries persist for over 6 months in most patients. Accumu...

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    abstract:BACKGROUND AND PURPOSE:Sporadic amyotrophic lateral sclerosis (sALS) is a devastating neurodegenerative disease, which results from complex genetic and environmental interactions. Recent studies have reported an association between several polymorphisms of the PON1 and PON2 genes and risk of sALS. The aim of the presen...

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  • [Mossbauer spectroscopy of iron in substantia nigra in Parkinson disease and controls].

    abstract::Mössbauer spectroscopy was used to study iron content, its redox state and binding sites in substantia nigra from parkinsonian and control brains. Measurements performed on fresh frozen samples demonstrated the presence of ferric iron only, both in disease and control. We found no difference in the total amount of iro...

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    doi:

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    abstract::A retrospective analysis of 58 patients with spontaneous SAH was conducted. 33 patients suffered on severe SAH, clinical grading IV and V (Hunt, Hess). 11 died without treatment due to decerebrate rigidity. 22 patients were treated, 16 underwent a clipping procedure and 6 were selected for endovascular coilembolizatio...

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    authors: Gräwe A,Meier U,Molsen HP

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  • [Disturbances of glucose metabolism in epilepsy and other neurodegenerative diseases].

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    authors: Szutowicz A,Jankowska A,Tomaszewicz M

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  • [Intradural spinal cysticercosis provoking radicular symptoms].

    abstract::The authors describe a case of spinal intracanal cysticercosis. The cysts were situated intradurally, provoking radicular symptoms: pain, paresis. CT investigations showed herniation of discs L4/L5 and L5/S1 interpreted as the cause of the mentioned symptoms. Surgical treatment included discectomy L4/L5 and L5/S1. Rec...

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