Abstract:
:The acute phase of spinal cord injury includes primary and secondary pathological patterns. Primary patterns include the effects of contusion, laceration, stretch of neural tissue and direct vascular trauma. These changes are irreversible. Secondary patterns include posttraumatic ischemic changes, loss of energy metabolism, oedema, release of cytotoxic substances such as free radicals, and electrolyte changes such as an increase in intracellular calcium ions. These changes may be reversible. This determines treatment strategies. Free-radical scavengers, opioid receptor antagonists include TRH and its analogues, calcium channel blockers, volume expander, osmotic diuretics, hypothermia, antioxidants, cycloxygenase inhibitors, serotonin antagonists and NMDA receptor antagonists were tested in experimental models during the last 4 years. The successful treatment should break the feedback loops and trails of secondary injury cascade in many places so combined treatment connected with many elements and surgery decompression is necessary.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Harat M,Radek A,Kochanowski Jsubject
Has Abstractpub_date
1996-01-01 00:00:00pages
123-35issue
1eissn
0028-3843issn
1897-4260journal_volume
30pub_type
杂志文章,评审abstract::Certain clinical aspects of extradurally situated spinal tumours are presented stressing their importance for the diagnosis and therapeutic approach. The role of pain as the first clinical symptom is emphasized. Of great importance are the plan X-ray films of the spine which in nearly 70% of cases reveal changes in bo...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:
更新日期:1993-03-01 00:00:00
abstract::The author reviews two decades of clinical research directed towards the links between disturbances of the oculomotor functions and the severity and progress of Alzheimer's disease. Two basically different streams of research are identified. The first based on precise, quantitative examination of automatic or reflexiv...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract::The authors report a case of coexistence of Eales disease and multiple sclerosis in which signs of perivenous retinitis preceded by 25 years the appearance of neurological changes. Considering the similarity in the course of both disease and the histological character of perivascular changes the authors suggest presen...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1988-07-01 00:00:00
abstract::The authors present a case of Huntington disease in a 14 year old boy. The basis of genetic, pathoetiology, clinical course of disease, significance of molecular analysis of DNA are discussed. ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::The importance of binding antibodies (BAb) that develop during the treatment of multiple sclerosis with interferon beta has not been fully explained yet. However, they are generally regarded as one of factors that may diminish treatment efficacy. The aim of the study was to evaluate firstly, BAb occurrence in interfer...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study was to evaluate the concentration of 25(OH)D₃ and the indices of calcium and phosphorus metabolism at different times of relapsing-remitting multiple sclerosis (MS). The relationships between the concentrations of 25(OH)D₃ and the indices of calcium-phosphate metabolism were...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.5114/ninp.2013.34730
更新日期:2013-03-01 00:00:00
abstract::In 1974 an epidemic of lymphocytic cerebrospinal meningitis occurred in the Province of Bydgoszcz. Thirty-nine cases of this disease were hospitalized at the neurological department of the hospital in Grudziadz. Virological investigations demonstrated presence of Coxsackie A9 virus. The manifestations of the disease, ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1975-11-01 00:00:00
abstract::There is little information on the efficacy of various surgical interventions in terms of health-related quality of life in Parkinson's disease (PD) patients. Most studies evaluated only motor symptoms of PD after surgical treatment avoiding subjective patient's assessment. The goal of this study is the assessment of ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::The authors report two cases of familial progressive muscular atrophy of proximal localization, with late onset of signs which was associated with involvement of the motor nucleus of trigeminal nerve and hypoglossus nerve nucleus as well as with presence of gynaecomastia. Cases of coexistence of gynaecomastia with spi...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::An original method is presented used for production of experimental aneurysms in rats. The method may be useful in training for microneurosurgical treatment of aneurysms. ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:Guidelines for appropriate management of vestibular schwannomas in NF2 patients are controversial. In this paper we reviewed our experience with patients with NF2 for the results of surgical treatment with particular reference to hearing and facial nerve preservation. METHODS:We included in the study 30 pati...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.1016/j.pjnns.2015.06.008
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this paper is to present an alternative method of cranioplasty with the use of an autologous cranial bone flap stored between primary and restorative surgery in the subcutaneous pocket in the lateral hypogastric region. MATERIAL AND METHODS:Between January 1999 and April 2002, in the ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract::The use of spinal implants in the pediatric population is controversial in terms of skeletal immaturity. The authors present the case of a 12-year-old boy with displaced Type III odontoid fracture, successfully treated by direct screw fixation. Fractures defined as Type II and Type III according to the classification ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::In a group of 139 patients with poorly differentiated brain gliomas controlled clinical trial was carried out for assessment of two methods of postoperative treatment. After possibly radical removal of the glioma the patients were treated by radiotherapy with 60Co teletherapy in doses of 60 Gy (30 fr) in depth during ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1988-05-01 00:00:00
abstract::The pathological mechanism of pain in vertebral column diseases is discussed in accordance with the theory of Melzack and Wall taking into account both systems of pain sensation control at the spinal level and reticular formation level. The action of pain mediators is discussed as well. The main pathogenetic factors a...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::A case of brain stem injury of vascular and traumatic origin, complicated with metabolic disturbances and with finally achieved cure is described. ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::The aim of the work was to show the usefulness of neurological and radiological signs in the patients with L4 and L5 discopathy. The axial symptoms with the highest occurrence frequency and the differential symptoms closely connected with definite disc pathology: the type and/or the level of discopathy were defined. T...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract::The neurological and electroneurographic assessment was carried out in 56 patients with high-grade non-Hodgkin lymphomas. In 37 patients the neuropathological examination was also done. Polyneuropathy was the most frequent sign of nervous system involvement, observed in 40% of patients before chemotherapy and markedly...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::Dysarthria is an invalidating disability in ALS patients with motor neuron degeneration in the bulbar region. The methods to assess dysarthric disorders in ALS are seldom described in publications. This study was performed in 43 patients who had definite (n = 23) or probable (n = 20) ALS (of the bulbar group n = 15, o...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::Investigations were performed on 13 cats with epileptogenic focus developed after sectioning the optic chiasm and corpus callosum. Learning was begun 3 months after producing the epileptogenic focus by the aluminium method when it was bioelectrically active. Additionally in 6 cats DPH in daily doses of 10--15 mg/kg wa...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract::The intensity of perseveration was tested in 70 patients with generalized convulsive seizures and with partial seizures of complex symptomatology, and in 37 subjects without central nervous system diseases (controls). The results suggest that the tendency for perseveration is a feature occurring not only in epilepsy b...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Multiple sclerosis (MS) is the most common cause of neurological disability of young people. It is estimated that 40 000-60 000 people in the country suffer from MS, and approximately 2000 new cases are diagnosed annually. These are, however, estimated data and require verification by nation-wide research. Results pub...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.5114/ninp.2013.38228
更新日期:2013-09-01 00:00:00
abstract::Monoclonal gammopathy is responsible for about 10% of acquired peripheral neuropathies of unknown origin. Monoclonal gammopathy is the result of uncontrolled proliferation of a single clone of plasma cells producing the first class of immunoglobulin (M-protein). The routine diagnostic process of peripheral neuropathy ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::Developmental abnormalities or inflammatory disorders provoke deformations and instability of the craniocervical junction. The most dangerous results of these lesions are: sudden brainstem compression or cervical myelopathy. The authors propose the guidelines for surgical management of non-traumatic deformities caused...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:
更新日期:2002-03-01 00:00:00
abstract::The authors describe a case of spontaneous intracerebral haematoma treated conservatively. After three months a large posthaemorrhagic cyst of the brain was found in the sensorimotor area. The authors suppose that in case of surgical treatment the course of the disease and its sequelae would have been much milder. The...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Autoimmune diseases are caused by a defect of the human immune system characterised by an inability to recognize their own antigens and by a pathological response against these antigens. Although the aetiology of these diseases is unknown, there is a number of cellular and molecular mechanisms which can underlie these...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:
更新日期:2007-05-01 00:00:00
abstract::The authors describe two cases of extramedullary tumours in the vertebral canal with long (7 and 15 years) course without pains and with clinical manifestations simulating Charcot-Marie-Tooth disease. It is stressed in conclusion that sporadic cases of this disease with involvement of the lower extremities only, with ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:INTRODUCTION:One of the leading causes of death in Poland is stroke. Cardiogenic stroke is known to be one of the most important reasons for acute ischaemic stroke (AIS), comprising 25-30% of all AISs. AIM OF STUDY:Assessment of the prevalence of different risk factors of cardiogenic causes of AIS using transthoracic ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.5603/PJNNS.a2019.0016
更新日期:2019-01-01 00:00:00
abstract::Microsurgical transsphenoidal approach has been for decades an established standard surgical treatment of pituitary adenomas. Actually it offers a safe and rapid midline access to the sellar region with a minimal risk of injury to vascular vessels, the optic chiasm or nerves and the brain. Major limitations of this ap...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-01 00:00:00
abstract::Conventional methods of neuroimaging, such as computed tomography and magnetic resonance imaging, are mostly useful in exclusion of movement disorders with secondary aetiology. Recently, the application of transcranial sonography has been introduced to the diagnosis of extrapyramidal diseases. This valuable technique,...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:10.1016/s0028-3843(14)60155-9
更新日期:2010-11-01 00:00:00