Cannabis use in the last year in a US national sample of twin and sibling pairs.

Abstract:

BACKGROUND:Three prior population-based twin studies, none of which was nationally representative, suggested that both genetic and familial-environmental factors contribute to family resemblance for lifetime cannabis use. We seek to replicate these results in a US national probability sample of twin and sibling pairs examining only last year cannabis use. METHODS:Cannabis use in the last year was assessed by self-report questionnaire. Biometrical twin analyses were performed. RESULTS:Twin and sibling resemblance for last-year cannabis use was substantial, and much higher in monozygotic pairs than in dizygotic and sibling pairs, where levels of resemblance were similar. Modeling suggested that sibling resemblance was due to genetic factors--with a heritability of at least 60% and probably family environmental factors. No evidence was found that cannabis use was influenced by a special twin environment. CONCLUSIONS:Consistent with prior studies, use of cannabis is substantially influenced by genetic factors but family-environment is also possibly of importance.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Kendler KS,Neale MC,Thornton LM,Aggen SH,Gilman SE,Kessler RC

doi

10.1017/s0033291701004950

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

551-4

issue

3

eissn

0033-2917

issn

1469-8978

journal_volume

32

pub_type

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