Abstract:
BACKGROUND:Three prior population-based twin studies, none of which was nationally representative, suggested that both genetic and familial-environmental factors contribute to family resemblance for lifetime cannabis use. We seek to replicate these results in a US national probability sample of twin and sibling pairs examining only last year cannabis use. METHODS:Cannabis use in the last year was assessed by self-report questionnaire. Biometrical twin analyses were performed. RESULTS:Twin and sibling resemblance for last-year cannabis use was substantial, and much higher in monozygotic pairs than in dizygotic and sibling pairs, where levels of resemblance were similar. Modeling suggested that sibling resemblance was due to genetic factors--with a heritability of at least 60% and probably family environmental factors. No evidence was found that cannabis use was influenced by a special twin environment. CONCLUSIONS:Consistent with prior studies, use of cannabis is substantially influenced by genetic factors but family-environment is also possibly of importance.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Kendler KS,Neale MC,Thornton LM,Aggen SH,Gilman SE,Kessler RCdoi
10.1017/s0033291701004950subject
Has Abstractpub_date
2002-04-01 00:00:00pages
551-4issue
3eissn
0033-2917issn
1469-8978journal_volume
32pub_type
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