Cancer genetics and cell and molecular biology. Is this the way forward?

abstract：:Adverse cardiovascular effects are commonly seen in severe theophylline poisoning. Primary ST-T wave changes have not been described previously. We report T wave inversion associated with severe theophylline toxicity in a 33-year-old woman with no evidence of organic heart disease. The T wave inversion resolved after ...

journal_title：Chest

authors： Kolander SA,Nydegger CC,Porter RS

更新日期：1989-08-01 00:00:00

abstract：:A patient presented with multisystem disease due to a very aggressive malignant thymoma. The case was complicated by the triad of cardiac tamponade, superior vena cava (SVC) syndrome, and disseminated intravascular coagulation (DIC). A review of the English literature reveals this to be a unique constellation of clini...

journal_title：Chest

authors： Dib HR,Friedman B,Khouli HI,Gerber DR,Weiss RL

更新日期：1994-03-01 00:00:00

abstract：:We report a patient in whom presumed vasospasm of an angiographically normal coronary artery led to severe transmural myocardial ischemia. To our knowledge, this is the first case in which an allergic reaction to locally applied chlorhexidine caused such a severe reaction. ...

journal_title：Chest

authors： Conraads VM,Jorens PG,Ebo DG,Claeys MJ,Bosmans JM,Vrints CJ

更新日期：1998-05-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the chest radiographic filling pattern associated with partial liquid ventilation (PLV) with the perfluorochemical perflubron (LiquiVent; Alliance Pharmaceutical Corp; San Diego CA) as a function of dose and timing. DESIGN:Post hoc review of chest radiographs by three independent observers...

journal_title：Chest

authors： Schuster DP,Lange NR,Tutuncu A,Wedel M,LiquiVent Study Group.

更新日期：2001-05-01 00:00:00

abstract：STUDY OBJECTIVE:To determine if animals with abnormally low albumin levels are more susceptible to the effects of hypercapnia on BP compared to normal animals. DESIGN:Prospective, controlled laboratory experiment. SETTING:University research laboratory. ANIMALS:Eighteen male Sprague-Dawley rats: 6 rats 10 to 12 week...

journal_title：Chest

authors： Gómez JL,Gunnerson KJ,Song M,Li J,Kellum JA

更新日期：2007-05-01 00:00:00

abstract：:Direct mechanical ventricular actuation (DMVA) is a non-blood-contacting method of biventricular cardiac massage which may be applied expediently for total circulatory support. The purpose of this study was to assess the feasibility of DMVA application for patients suffering refractory cardiac arrest. Following inform...

journal_title：Chest

authors： Anstadt MP,Bartlett RL,Malone JP,Brown GR,Martin S,Nolan DJ,Oberheu KH,Anstadt GL

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Self-reported tobacco pack-year history plays a large role in decisions about low-dose CT screening for lung cancer, yet is challenging to measure accurately. RESEARCH QUESTION:To what extent does random measurement error in pack-year information impact screening decisions and screening effectiveness? STUD...

journal_title：Chest

authors： Caverly TJ,Zhang X,Hayward RA,Zhu J,Waljee AK

更新日期：2020-09-14 00:00:00

abstract：:The two-dimensional cross-sectional echocardiographic diagnosis of bicuspid aortic valves is described and compared with results of M-mode echocardiograms. Aortic valve anatomy was determined in 19 selected patients by angiography, and confirmed in five by direct surgical visualization. Using an eccentricity index (EI...

journal_title：Chest

authors： Fowles RE,Martin RP,Abrams JM,Schapira JN,French JW,Popp RL

更新日期：1979-04-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the efficacy of negative pressure ventilation (NPV) in avoiding or reducing apneas and related hypoxemia and respiratory acidosis during laser therapy (LT) of endobronchial lesions. DESIGN:A prospective, controlled, randomized study. SETTING:An operating theater of a respiratory endoscopy ...

journal_title：Chest

authors： Vitacca M,Natalini G,Cavaliere S,Clini E,Foccoli P,Candiani A,Ambrosino N

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:A pulmonary right-to-left shunt (RLS) carries the risk of cerebral paradoxical embolization and severe neurologic complications. Recognizing patients at risk is important to facilitate appropriate management strategies, but a direct relation between pulmonary shunt size and risk of complications remains cont...

journal_title：Chest

authors： Velthuis S,Buscarini E,van Gent MWF,Gazzaniga P,Manfredi G,Danesino C,Schonewille WJ,Westermann CJJ,Snijder RJ,Mager JJ,Post MC

更新日期：2013-08-01 00:00:00

abstract：:Thirteen patients with stable airway disease were fed a diet high in carbohydrates, and 35 minutes later metabolic and ventilatory effects were observed. The six patients who did not retain carbon dioxide increased their mean respiratory quotient from 0.86 +/- 0.07 to 1.03 +/- 0.04, their mean minute ventilation from ...

journal_title：Chest

authors： Gieseke T,Gurushanthaiah G,Glauser FL

更新日期：1977-01-01 00:00:00

abstract：:Propofol, a new intravenous sedative agent, was investigated in 41 asthmatic patients undergoing day-case (outpatient) fiberoptic bronchoscopy. The study design was a randomized comparison between propofol and midazolam, which is a well-established intravenous sedative agent. The age, weight, and American Society of A...

journal_title：Chest

authors： Clarkson K,Power CK,O'Connell F,Pathmakanthan S,Burke CM

更新日期：1993-10-01 00:00:00

abstract：:Relationships were investigated between chronic bronchitis and plant dust exposure assessed by quantification of barn threshing and cattle foddering and chronic bronchitis and acute respiratory syndromes after plant mold dust exposure. Two groups of male dairy farmers were studied in the Doubs region, France: 197 with...

journal_title：Chest

authors： Dalphin JC,Pernet D,Dubiez A,Debieuvre D,Allemand H,Depierre A

更新日期：1993-02-01 00:00:00

abstract：STUDY OBJECTIVE:This study aimed to determine the differences between ciliary beat frequencies of respiratory ciliated cells from peripheral bronchioles and from proximal bronchi in humans. DESIGN:Measurements were made from resected lungs. Ciliated cells were harvested by brushing the mucosa of each site immediately ...

journal_title：Chest

authors： Clary-Meinesz C,Mouroux J,Huitorel P,Cosson J,Schoevaert D,Blaive B

更新日期：1997-03-01 00:00:00

abstract：:The effect of clenbuterol, a beta adrenergic drug, and ambroxol, a secretolytic agent, on regional mucociliary clearance and pulmonary radioaerosol distribution was investigated in two groups of 15 patients with COLD in a double-blind cross-over trial with placebo. Clearance rates of inhaled 99mTc-labelled human serum...

journal_title：Chest

authors： Weiss T,Dorow P,Felix R

更新日期：1981-12-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the safety and efficacy of additional minocycline pleurodesis after thoracoscopic treatment of primary spontaneous pneumothorax. DESIGN:Retrospective comparative study with a historical control. SETTING:Thoracic surgical division of a university-affiliated tertiary medical center. PATIENT...

journal_title：Chest

authors： Chen JS,Hsu HH,Kuo SW,Tsai PR,Chen RJ,Lee JM,Lee YC

更新日期：2004-01-01 00:00:00

abstract：:A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be ass...

journal_title：Chest

authors： Roberts A,Kagan A,Rhoads GG,Pierce JA,Bruce RM

更新日期：1977-10-01 00:00:00

abstract：:There exists a high prevalence of OSA in the general population, a great proportion of which remains undiagnosed. The snoring, tiredness, observed apnea, high BP, BMI, age, neck circumference, and male gender (STOP-Bang) questionnaire was specifically developed to meet the need for a reliable, concise, and easy-to-use...

journal_title：Chest

authors： Chung F,Abdullah HR,Liao P

更新日期：2016-03-01 00:00:00

abstract：:The pathogenesis and clinical manifestations of COPD are not restricted to pulmonary inflammation and structural remodeling. Rather, this disorder is associated with clinically significant systemic alterations in biochemistry and organ function. The systemic aspects of COPD include oxidative stress and altered circula...

journal_title：Chest

authors： Wouters EF,Creutzberg EC,Schols AM

更新日期：2002-05-01 00:00:00

abstract：:The previously unreported association of chronic persistent cough due to a duplication esophageal cyst is presented. The presence of a long history of atopy, bronchitis, and asthma resulted in a delay in diagnosis. When vigorous bronchodilator therapy was unsuccessful, close observation of the patient and review of he...

journal_title：Chest

authors： Bowton DL,Katz PO

更新日期：1984-07-01 00:00:00

abstract：:Sleep health is a multidimensional construct that includes adequate duration, quality, and appropriately timed sleep that may be influenced by environmental factors. In this review, we focus on how an individual's living and sleeping environment, both the surrounding neighborhood physical and social features and the a...

journal_title：Chest

authors： Billings ME,Hale L,Johnson DA

更新日期：2020-05-01 00:00:00

abstract：:Transesophageal echocardiography (TEE) is a safe and minimally invasive tool that can routinely provide high-quality anatomic and hemodynamic information in the severely ill. Despite its potential for frontline acute care clinicians, TEE use has typically been reserved for diagnostic experts in the cardiac-surgical mi...

journal_title：Chest

authors： Jaidka A,Hobbs H,Koenig S,Millington SJ,Arntfield RT

更新日期：2019-01-01 00:00:00

abstract：:Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...

journal_title：Chest

authors： Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

更新日期：2011-11-01 00:00:00

abstract：STUDY OBJECTIVES:Although videothoracoscopic (VTS) resection of Masaoka stage I thymoma has been reported to be a less invasive method than open thoracotomy and to achieve a comparable surgical outcome, the usefulness of this method in the treatment of stage II thymoma has not yet been prospectively evaluated. We there...

journal_title：Chest

authors： Cheng YJ,Kao EL,Chou SH

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is recognized as a stroke risk factor in atrial fibrillation (AF). Patients with diabetes with retinopathy have an increased risk for systemic cardiovascular complications, and severe diabetic retinopathy predisposes to ocular bleeding. We hypothesized that patients with diabetes, retinopat...

journal_title：Chest

authors： Lip GYH,Clementy N,Pierre B,Boyer M,Fauchier L

更新日期：2015-04-01 00:00:00

abstract：:Pulmonary Langerhans cell histiocytosis, also known as eosinophilic granuloma, is an uncommon interstitial lung disease. A solitary nodule, usually parenchymal, may rarely be the only manifestation of the disease. We describe a case of Langerhans cell histiocytosis presenting as an obstructing tracheal lesion in a 55-...

journal_title：Chest

authors： Fridlender ZG,Glazer M,Amir G,Berkman N

更新日期：2005-08-01 00:00:00

abstract：:We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infu...

journal_title：Chest

authors： Silverman HJ,Tuma P

更新日期：1992-07-01 00:00:00

abstract：:The production of cytotoxic oxygen radicals by activated granulocytes is a proposed mechanism of lung injury in ARDS. Protective effects of N-acetylcysteine (NAC) have been described in experimental and clinical ARDS. NAC could act in part by replenishing the intracellular stores of glutathione (GSH) in activated gran...

journal_title：Chest

authors： Laurent T,Markert M,Feihl F,Schaller MD,Perret C

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2) have been shown to play an important role in transepithelial migration of neutrophil granulocytes during inflammation in various tissues. This study investigated the regulation of gene expression and surface expression of CXCR1 and CXCR2...

journal_title：Chest

authors： Farkas L,Hahn MC,Schmoczer M,Jentsch N,Krätzel K,Pfeifer M,Schulz C

更新日期：2005-11-01 00:00:00

abstract：:We assessed qualitative and quantitative differences in surfactant lipid composition of bronchoalveolar lavage (BAL) fluid in patients with acquired immune deficiency syndrome (AIDS) and Pneumocystis carinii (PC) pneumonia. Five normal volunteers and 27 patients with human immunodeficiency virus (HIV) infection underw...

journal_title：Chest

authors： Hoffman AG,Lawrence MG,Ognibene FP,Suffredini AF,Lipschik GY,Kovacs JA,Masur H,Shelhamer JH

更新日期：1992-12-01 00:00:00