当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Gestational pyelonephritis--associated Escherichia coli isolates represent a nonrandom, closely related population.

Gestational pyelonephritis--associated Escherichia coli isolates represent a nonrandom, closely related population.

Abstract：

OBJECTIVE:A select group of Escherichia coli strains known as uropathogenic cause pyelonephritis in nonpregnant individuals. We investigated whether Escherichia coli from gestational pyelonephritis represent a random population or possess common uropathogenic characteristics. STUDY DESIGN:Repetitive element sequence-based polymerase chain reaction, plasmid profiles, hemolysin, and O serotypes were assayed from Escherichia coli isolates of 57 pregnant patients with acute pyelonephritis at different gestational ages. RESULTS:The majority of the first trimester isolates fell primarily into repetitive element sequence-based patterns 1 and 3 and O6, O15, and O75 serotypes. Second-trimester isolates had multiple patterns with high-frequency repetitive element sequence-based polymerase chain reaction 1 and 5 and an unknown (OX) serotype. Pattern 3, predominantly O75 serotype, was found primarily among third-trimester isolates. CONCLUSION:It is likely that Escherichia coli associated with acute pyelonephritis during different trimesters of pregnancy represents nonrandom closely related isolates, and some of these strains may be characteristic in pregnant patients only.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Hart A,Pham T,Nowicki S,Whorton EB Jr,Martens MG,Anderson GD,Nowicki BJ

doi

10.1016/s0002-9378(96)70337-x

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

983-9

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(96)70337-X

journal_volume

174

pub_type

杂志文章

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