Abstract:
:Either Actinomyces israeli, A. naeslundii, or Arachnia propionica was found, by immunofluorescence studies, in cervicovaginal mucus from 36% of 50 women. One or more of these organisms were found in a surprising 27% of those with neither intrauterine contraceptive devices (IUDs) nor intravaginal foreign bodies. The only common finding was abundant vaginal mucus, and no clinical features were more serious than vaginal itching, odor, or vague discomfort. Among those women who harbored actinomycetes, the average duration of continuous IUD use was 5.3 years; the comparable figure for those with no infection was 2.1 years. :This study compares the presence of Actinomyces in the vaginas of women with and without IUDs. Mucus samples were collected from the external cervical os of 50 randomly selected women. The smears were air-dried, heat-fixed, and stained directly with fluorescent antibody conjugates for A. israelii, A. naeslundii, and Arachnia propionica (Actinomyces species with clinical significance in human beings). A fluorescent microscope with oil immersion magnification of about 400x was used, and identification of the specific organisms depended upon both cellular morphologic features and the brilliant greenish yellow fluorescence of the cell membrane. Either 1 of 3 A. species was positively identified in 18 of 50 patients (36%). 1 or more species were found in 8 of 30 patients with no internal devices (27%). Of 18 IUD wearers, 8 were positive for Actinomyces (44%). 1 patient with a retained vaginal tampon and another 1 with a pessary also had positive smears. A. israelii and Arachnia propionica were the most commonly identified species. If the organism was found, average duration of continuous IUD use was 5.3 years (range, 1 to 15 years). Where these organisms do not exist, average continuous use was 2.1 years. Age of patients positive for Actinomyces ranged from 18 to 52 years. These findings do not show the true incidence of these organisms in either the general population or IUD wearers. However, they suggest the presence of such organisms in asymptomatic women, with or without intravaginal devices. Papanicolaou staining is not sufficient in identifying the presence of the organisms. Further studies must be done. The immunofluorescence technique is a simple, rapid and universally available technique for identifying the organism. Further studies should be done to determine whether these organisms lie dormant until some pathogens or trauma precipitate disease. Also, the disease actinomycosis should be carefully distinguished from the mere presence of Actinomycetaceae in the vagina.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Curtis EM,Pine Ldoi
10.1016/0002-9378(81)90078-8subject
Has Abstractpub_date
1981-08-15 00:00:00pages
880-4issue
8eissn
0002-9378issn
1097-6868pii
0002-9378(81)90078-8journal_volume
140pub_type
杂志文章abstract:OBJECTIVE:Amniotic fluid embolism syndrome is a fatal disease in pregnant women. The exact role of platelets and neutrophils in amniotic fluid embolism syndrome is not clear. We examined whether amniotic fluid could affect platelet-neutrophil aggregation and activation and the possible mechanisms. STUDY DESIGN:Blood s...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2013.01.012
更新日期:2013-04-01 00:00:00
abstract::This study examines the use of episiotomy and the frequency of perineal lacerations in a primary care maternity center staffed by certified nurse midwives (Booth Maternity Center) and a tertiary care teaching hospital where deliveries were performed by physicians (Thomas Jefferson University Hospital). The study sampl...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(89)90158-0
更新日期:1989-05-01 00:00:00
abstract::The relationship of maternal amino acids, proteins, and certain other factors to fetal development (weight and cranial volume at birth and mental and motor scores at 8 months of age) was investigated in 129 gravidas. Maternal prepregnancy weight was significantly related to birth weight and cranial volume in the newbo...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(16)33441-x
更新日期:1975-10-15 00:00:00
abstract:OBJECTIVE:To determine maternal and perinatal outcome in women with severe preeclampsia at <26 weeks according to gestational age at the onset of expectant management and the presence of severe fetal growth restriction (<5th percentile). STUDY DESIGN:Fifty-one patients (53 fetuses; 2 twins) were retrospectively studie...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2011.06.062
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:We evaluated four oral combinations of conjugated estrogens (Premarin) and medroxyprogesterone acetate in preventing endometrial hyperplasia, which can occur with conjugated estrogens alone. STUDY DESIGN:This was a 1-year prospective, double-blind, randomized, multicenter study in 1724 postmenopausal women. ...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9378(94)70129-6
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:The diagnostic criteria for preeclampsia have evolved from the traditional definition of de novo hypertension and proteinuria to a broader definition of hypertension with evidence of end-organ dysfunction. Although this change is endorsed by various societies such as the International Society for the Study o...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2020.08.019
更新日期:2020-08-12 00:00:00
abstract::Continuous measurements of fetal heart rate (FHR), gross fetal body movements, fetal breathing movements, and maternal heart rate (MHR) were made for 24-hour observation intervals in 11 pregnant women at 38 to 40 weeks. There was a significant positive correlation between each mother's daily mean MHR and her fetus' da...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(82)90222-8
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine whether nutritional components other than high maternal blood phenylalanine levels (> or = 10 mg/dL) are associated with congenital heart defects in the offspring of women with hyperphenylalaninemia. STUDY DESIGN:Of the 414 subjects who had live births, 249 women (6...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2002.124276
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:The study was undertaken to explore the antiproliferative mechanism of action of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo(b)pyran (K-1) in estradiol-induced rat uterine hyperplasia. STUDY DESIGN:Adult ovariectomized rats received vehicle or estradiol alone (20 μg/kg) or estradiol along with K-...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2011.05.024
更新日期:2011-10-01 00:00:00
abstract::In this study the immediate neonatal acid-base status, obtained via a double-clamped segment of umbilical cord, in 75 term, singleton vaginal deliveries was compared to electronic fetal heart rate recordings and Apgar scores. Of 75 neonates, 59 had 1-minute Apgar scores greater than or equal to 7 and 52 had an initial...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(86)90717-9
更新日期:1986-06-01 00:00:00
abstract::The recent birth of octuplets unleashed a firestorm of publicity, casting a harsh light on the mother and her presumed inadequacies as a parent. It also raised questions about the role of reproductive endocrinologists. Herein we consider 3 aspects of this question: should reproductive endocrinologists consider the eco...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2009.04.053
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to find out whether the effects of thermal stress on plasma catecholamines and plasma renin activity are altered by pregnancy. STUDY DESIGN:Nonpregnant (n = 15) and pregnant (13 to 14 weeks, n = 23; 36 to 37 weeks, n = 23) healthy women were examined. Samples were taken before t...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(11)91590-7
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the use-effectiveness of oral contraceptives (OCs) in Europe according to body mass index (BMI), weight, age, and other factors. STUDY DESIGN:In a planned secondary analysis, we used data from the European Active Surveillance Study on Oral Contraceptives, which was a p...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2009.03.017
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:Our purpose was to describe subsequent pregnancy outcome and long-term maternal prognosis in women with HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) during the index pregnancy. STUDY DESIGN:This is a descriptive and analytic study of women with HELLP syndrome admitted to E.H. Crump W...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(95)90099-3
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Fibroid tumors are the most common benign tumors in women of reproductive age. Treatment is usually indicated for those who are symptomatic, with different techniques being used. OBJECTIVE:The purpose of this study was to compare the long-term outcome of laparoscopic myomectomy with magnetic resonance-guide...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2018.09.002
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the significance of preterm acidosis and its risk factors. STUDY DESIGN:From a cohort of 786 consecutive singleton neonates who were born after spontaneous or iatrogenic preterm delivery at 24.0-33.6 weeks of gestation from January 1993 to December 2005 with an ev...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2007.07.009
更新日期:2007-09-01 00:00:00
abstract::Deaths related to pregnancy were relatively common in the United States at the beginning of the twentieth century. A dramatic reduction of 99% in maternal mortality rate, from 850.0-7.5 per 100,000 live births from 1900-1982, is 1 of the most noteworthy public health success stories of the time period. This plateau co...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.ajog.2019.01.211
更新日期:2019-07-01 00:00:00
abstract::We investigated the effects of nifedipine, a calcium entry blocker, on the fetal and maternal circulation. Nifedipine was administered intravenously for 30 minutes to chronically instrumented pregnant ewes. Infusion of 5 micrograms.kg-1.min-1 resulted in a 30% to 50% increase in total and regional fetal cerebral blood...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(87)80104-7
更新日期:1987-10-01 00:00:00
abstract:BACKGROUND:The process of childbirth is one of the most crucial events in the future health and development of the offspring. The vulnerability of parturients and fetuses during the delivery process led to the development of intrapartum monitoring methods and to the emergence of alternative methods of delivery. However...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2020.05.025
更新日期:2020-09-01 00:00:00
abstract::Sterilization by fimbriectomy has been thought to be irreversible. The present report describes the surgical approach and results in nine patients after microsurgical tubal reconstruction and indicates that repeated pregnancy is possible after fimbriectomy reversal. Preoperative radiographic studies were used to docum...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(80)90775-9
更新日期:1980-05-15 00:00:00
abstract::A prospective study of 383 patients with suspected ectopic pregnancy was carried out at Yale-New Haven Hospital to determine the value of adnexal sonographic findings in the diagnosis of ectopic pregnancy. In patients with adnexal sonographic results and human chorionic gonadotropin titers less than 6000 mIU/ml (n = 2...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(88)90774-0
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:Our aim was to determine whether early second-look lysis of adhesions reduces postoperative adhesions. STUDY DESIGN:With the murine uterine horn model, early second-look lysis of adhesions was performed 5, 7, 14, and 21 days after an electrocautery injury. Sites with adhesions (between 36 and 46/time point) ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(98)70366-7
更新日期:1998-08-01 00:00:00
abstract::Cyclic adenosine 3',5'-monophosphate is known to modulate smooth muscle contractility. Because both relaxin and progesterone have been demonstrated to affect myometrial cyclic adenosine monophosphate activity, we questioned whether the previously observed synergism of these two hormones in inhibiting uterine contracti...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(88)90564-9
更新日期:1988-12-01 00:00:00
abstract::Comparisons of two methods of sterilization on 250 patients at Victoria General Hospital, Nova Scotia, Canada between January 1968 and December 1970. There were 85 vaginal procedures and 165 abdominal procedures; 50 cases were lost to follow-up. Average age of the women was 35 years, average parity was 3.5 children....
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(73)90397-9
更新日期:1973-02-15 00:00:00
abstract::We describe the first pregnancy in a homozygous familial hypercholesterolemic woman who started plasma exchange therapy 3 years before she became pregnant. We especially studied the effects of plasma exchange on lipid profile, uteroplacental circulation, and pregnancy course. ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(90)90824-q
更新日期:1990-01-01 00:00:00
abstract::The present investigation was designed to reassess the fractional postcoital test (PCT). Specifically, the study addressed the question of whether the internal cervical mucus sperm count is significantly different from the sperm counts at other cervical levels. By means of standardized methodology, 25 normal postcoita...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(79)90056-5
更新日期:1979-02-15 00:00:00
abstract:OBJECTIVE:We sought to establish the lowest dose of 3-keto-desogestrel, when added to a copper-releasing intrauterine contraceptive device, that is needed to reduce menstrual blood loss to a very low level and to treat (essential) menorrhagia successfully. STUDY DESIGN:A double-blind group comparative study was design...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mob.2000.104805
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:An infrequent clinical dilemma arises when a patient with uterine prolapse that is best treated vaginally is discovered to have coexisting endometrial cancer. Often the underlying cancer is only discovered intraoperatively or postoperatively. We have reviewed our experience in this situation in an effort to e...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/0002-9378(95)91399-8
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVE:Our purpose was to evaluate the role of testing for intermediate- and high-risk human papillomavirus by use of a hybrid capture technique for predicting which patients with abnormal Papanicolaou smears are most likely to have squamous intraepithelial lesions or cancer. STUDY DESIGN:Cervical cytologic studies...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(95)91473-0
更新日期:1995-04-01 00:00:00
abstract::Ovaries from six women with normal menstrual cycles, a follicle wall biopsy specimen from a gonadotropin-stimulated preovulatory ovary, and a corpus luteum of pregnancy were examined by immunohistochemistry for the presence of immunoreactive renin and angiotensin II. Both antisera densely stained thecal and stromal ce...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(89)90077-x
更新日期:1989-01-01 00:00:00