Oral contraceptive effectiveness according to body mass index, weight, age, and other factors.

Abstract:

OBJECTIVE:The purpose of this study was to assess the use-effectiveness of oral contraceptives (OCs) in Europe according to body mass index (BMI), weight, age, and other factors. STUDY DESIGN:In a planned secondary analysis, we used data from the European Active Surveillance Study on Oral Contraceptives, which was a prospective active cohort surveillance study of 59,510 OC users, to assess the effectiveness of OCs overall and by BMI, weight, age, duration of use, ethinylestradiol dose, regimen type, starting/switching status, and parity. Self-reported unplanned pregnancies during OC use were confirmed by interview. RESULTS:An analysis of OC effectiveness (112,659 women-years of exposure and 545 unplanned pregnancies) found little variation in effectiveness by BMI/weight. Failure rates decreased after 30 years of age and with an increasing duration of use. CONCLUSION:OC users in Europe reported high contraceptive effectiveness with "typical use." Failure rates decreased with age and duration of use. BMI and weight had little, if any, influence on effectiveness.

journal_name

Am J Obstet Gynecol

authors

Dinger JC,Cronin M,Möhner S,Schellschmidt I,Minh TD,Westhoff C

doi

10.1016/j.ajog.2009.03.017

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

263.e1-9

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(09)00272-5

journal_volume

201

pub_type

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