Vesicular monoamine transporter in microvesicles from bovine posterior pituitaries is immunologically similar to but distinct from the chromaffin granule counterpart in its sensitivities to 1-methyl-4-phenylpyridinium and histamine.

abstract：:Interleukin-10 (IL-10) is a cytokine with many regulatory functions. In particular, IL-10 exerts neutralizing effect on other cytokines, and therefore IL-10 is thought to have important therapeutic implications. Recent reports suggest that IL-10 regulates not only immunocytes but also collagen and collagenase gene exp...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto T,Eckes B,Krieg T

更新日期：2001-02-16 00:00:00

abstract：:Metyrapone, an inhibitor of cytochrome P-450-dependent monooxygenases, enhanced the induction of tyrosine aminotransferase by dexamethasone in primary cultures of hepatocytes, while it had no effect on the basal level of the enzyme activity in the absence of the hormone. The amplification of the hormonal induction of ...

journal_title：Biochemical and biophysical research communications

authors： Tongiani R,Piazzolla S,Paolicchi A

更新日期：1990-01-30 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs that are emerging as important post-transcriptional gene regulators. miR-206 is unique in that it is expressed only in skeletal muscle, including the myoblastic C2C12 cell line. In C2C12 cells, miR-206 expression was reduced dramatically after bone morphogenetic protein (BM...

journal_title：Biochemical and biophysical research communications

authors： Sato MM,Nashimoto M,Katagiri T,Yawaka Y,Tamura M

更新日期：2009-05-22 00:00:00

abstract：:p70 S6 kinase (p70 S6k) is important in regulating a variety of cellular functions including mRNA translation and cell cycle progression and is activated by mitogens and hormones. Unexpectedly, we have found that, in adult rat cardiomyocytes, arsenite, which generally induces stress responses, markedly and rapidly act...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Proud CG

更新日期：1997-09-08 00:00:00

abstract：:Ribonuclease inhibitors were purified from the latent ribonuclease fractions of porcine thyroid and liver and used to test the hypothesis that their inhibition of bovine pancreatic ribonuclease A is correctly described by tight-binding rather than Michaelis-Menton kinetics. Both proteins were found to act as slow, tig...

journal_title：Biochemical and biophysical research communications

authors： Turner PM,Lerea KM,Kull FJ

更新日期：1983-08-12 00:00:00

abstract：:We have recently reported that mutant but not wild-type (wt) p53 protein was ADP-ribosylated in primary rat cells overexpressing the temperature-sensitive murine p53val135 gene. To examine whether the lack of susceptibility to modification is a specific feature of p53val135 adopting wt conformation or rather a general...

journal_title：Biochemical and biophysical research communications

authors： Wesierska-Gadek J,Schmid G,Cerni C

更新日期：1996-07-05 00:00:00

abstract：:Nitrous oxide affects dioxygen utilization by both bean seed and bovine heart submitochondrial particles when either succinate or reduced cytochrome c are used as substrates. Bovine heart particles exhibit reversible, dose-dependent partial inhibition of respiratory activity when exposed to N2O. Bean seed particle res...

journal_title：Biochemical and biophysical research communications

authors： Sowa S,Dong A,Roos EE,Caughey WS

更新日期：1987-04-29 00:00:00

abstract：:The thermophilic, obligately chemolithoautotrophic hydrogen-oxidizing bacterium, Hydrogenobacter thermophilus TK-6, assimilates carbon dioxide via the reductive tricarboxylic acid cycle. A gene cluster, porEDABG, encoding pyruvate:ferredoxin oxidoreductase (POR), which plays a key role in this cycle, was cloned and se...

journal_title：Biochemical and biophysical research communications

authors： Ikeda T,Ochiai T,Morita S,Nishiyama A,Yamada E,Arai H,Ishii M,Igarashi Y

更新日期：2006-02-03 00:00:00

abstract：:Receptor activator of nuclear factor kappa B (RANK) is a tumor necrosis factor receptor (TNFR) family protein that plays an important role in the regulation of bone and immune systems. Cellular responses to RANK ligand (RANKL) and the signal transduction pathways of RANK have been well characterized in osteoclasts and...

journal_title：Biochemical and biophysical research communications

authors： Lee ZH,Kim HH

更新日期：2003-05-30 00:00:00

abstract：:Leprechaunism is an inherited disorder characterized by growth restriction and severe insulin resistance and caused by mutations in the insulin receptor gene. Cells from these patients have defective insulin binding. Fibroblasts from some patients have concomitant defects in other tyrosine kinase receptors, such as th...

journal_title：Biochemical and biophysical research communications

authors： Longo N

更新日期：1993-12-15 00:00:00

abstract：:MicroRNAs (miRNAs) can negatively regulate gene expression and also induce or inhibit viral replication. In the present study, we found 10 miRNAs were differentially expressed in a stable HBV-producing cell line (HepG2.2.15) compared with its control cell line (HepG2) by miRNA array analysis. miR-501 was significantly...

journal_title：Biochemical and biophysical research communications

authors： Jin J,Tang S,Xia L,Du R,Xie H,Song J,Fan R,Bi Q,Chen Z,Yang G,Liu J,Shi Y,Fan D

更新日期：2013-01-25 00:00:00

abstract：:Adenovirus DNA synthesis carried out in vitro was inhibited by the aphidicolin. However, 30% of the DNA synthesis was resistant to aphidicolin even at a concentration of 200 micrograms/ml. When the distribution patterns of the radioactivity of the products synthesized in the presence of 50 micrograms/ml of the drug wa...

journal_title：Biochemical and biophysical research communications

authors： Ariga H

更新日期：1983-05-31 00:00:00

abstract：:Dinoflagellates are protists with permanently condensed chromosomes that lack histones and whose nuclear membrane remains intact during mitosis. These unusual nuclear characters have suggested that the typical cell cycle regulators might be slightly different than those in more typical eukaryotes. To test this, a cycl...

journal_title：Biochemical and biophysical research communications

authors： Bertomeu T,Morse D

更新日期：2004-10-29 00:00:00

abstract：:The gene encoding a red-shifted green fluorescent protein variant (EGFP) was introduced into a human immunodeficiency virus type 1 (HIV-1) molecular clone by replacing the nef gene. The EGFP-expressing HIV-1 replicated efficiently in established human T cells. The expression of EGFP in the virus-infected cells was con...

journal_title：Biochemical and biophysical research communications

authors： Lee AH,Han JM,Sung YC

更新日期：1997-04-07 00:00:00

abstract：:We developed PeptiSite, a comprehensive and reliable database of biologically and structurally characterized peptide-binding sites, in which each site is represented by an ensemble of its complexes with protein, peptide and small molecule partners. The unique features of the database include: (1) the ensemble site rep...

journal_title：Biochemical and biophysical research communications

authors： Acharya C,Kufareva I,Ilatovskiy AV,Abagyan R

更新日期：2014-03-21 00:00:00

abstract：:Previously we found a depression in the activity of hepatic xanthine dehydrogenase in rats fed clofibrate or di(2-ethylhexyl)phthalate. The present study further demonstrated that dietary addition of other peroxisome proliferators, including bezafibrate, dehydroepiandrosterone and perfluoro-n-octanoic acid also depres...

journal_title：Biochemical and biophysical research communications

authors： Satoh A,Sasago S,Takahashi S,Kato N

更新日期：1993-09-15 00:00:00

abstract：:Incubation of isolated mitochondria in the presence of malonyl-CoA prevented proteolysis of the outer carnitine palmitoyltransferase by Nagarse and trypsin. Malonyl-CoA had no direct action on trypsin when present in a chromogenic assay system for proteolysis or when preincubated with the proteases in the absence of m...

journal_title：Biochemical and biophysical research communications

authors： Kashfi K,Cook GA

更新日期：1991-07-31 00:00:00

abstract：:The alpha-subunit secreted by Chang human liver cells was labeled in vitro with [35S]Met, [3H]GlcN, or [3H]Fuc, and the biosynthetic products were studied by SDS-PAGE. Cells labeled with [35S]Met secreted a homogeneous 23K-24K alpha. In contrast, alpha secreted from cells labeled with [3H]GlcN and [3H]Fuc in the absen...

journal_title：Biochemical and biophysical research communications

authors： Morrow JS,Weintraub BD,Rosen SW

更新日期：1983-04-15 00:00:00

abstract：:We have demonstrated binding sites for LTB4 in guinea pig lung membranes. Binding of [3H]-LTB4 was of high affinity (Kd = 0.76 nM), saturable and linear with protein concentration (0.2-1.2 mg/ml). Scatchard and Hill's plot analysis indicated a single class of binding site with a Hill's coefficient of 0.99 +/- 0.08 (n ...

journal_title：Biochemical and biophysical research communications

authors： Saad M,Wong K

更新日期：1987-02-27 00:00:00

abstract：:1,25-Dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] initiates the hydrolysis of sphingomyelin in ROS 17/2.8 osteosarcoma cells with the resultant generation of cell-associated ceramide. Increases in ceramide levels were detectable at 15 min and maximal one hour after exposure of cells to 1,25(OH)(2)D(3). Neither 1,25(OH)(2)D...

journal_title：Biochemical and biophysical research communications

authors： Liu R,Xu Y,Farach-Carson MC,Vogel JJ,Karin NJ

更新日期：2000-06-24 00:00:00

abstract：:Until now, voltage-gated Ca(2+) channel proteins have been found only in eukaryotes. Here we report that a gene recently discovered in the eubacterium Bacillus halodurans codes for a protein closely related to eukaryotic Ca(2+) channels, but that has only one 6-transmembrane-segement (6TM) motif, instead of four, in i...

journal_title：Biochemical and biophysical research communications

authors： Durell SR,Guy HR

更新日期：2001-03-02 00:00:00

abstract：:In general, viral infection is supposed to induce stress responses in the host cell. However, very few detailed observations about virus-induced stress responses have been reported. Here we investigated specific stress responses in Vero cells infected with Sindbis virus (SV), a single-stranded RNA virus, acute infecti...

journal_title：Biochemical and biophysical research communications

authors： Nakatsue T,Katoh I,Nakamura S,Takahashi Y,Ikawa Y,Yoshinaka Y

更新日期：1998-12-09 00:00:00

abstract：:Incubation of purified bovine photoreceptor rod outer segments with [gamma-32P]ATP resulted in the labeling of phosphatidylinositol 4-phosphate (PIP) and phosphatidic acid (PA) with little labeling of phosphatidylinositol 4,5-bisphosphate (PIP2). Propranolol inhibited in a dose-dependent manner the labeling of PA and ...

journal_title：Biochemical and biophysical research communications

authors： Van Rooijen LA,Bazan NG

更新日期：1986-01-14 00:00:00

abstract：:The neural stem cell (NSC) niche in subventricular zone (SVZ) of adult mammalian brain contains dense vascular plexus, where endothelial cells (ECs) regulate NSCs by releasing plenty of angiocrine factors. However, the role of ECs-derived exosomes, a novel type of mediators of intercellular communications, in the regu...

journal_title：Biochemical and biophysical research communications

authors： Zhang YZ,Liu F,Song CG,Cao XL,Zhang YF,Wu HN,Guo CJ,Li YQ,Zheng QJ,Zheng MH,Han H

更新日期：2018-01-01 00:00:00

abstract：:A family of proteins, Homers 1, 2 and 3, involved in activity-dependent control of signal transduction has been recently described in neurons [Xiao, B., Tu, C. J., Petralia, R. S., Yuan, J. P., Doan, A., Breder, C. D., Ruggiero, A., Lanahan, A. A., Wenthold, R. J., and Worley, P. F. (1998) Homer regulates the associat...

journal_title：Biochemical and biophysical research communications

authors： Sandonà D,Tibaldo E,Volpe P

更新日期：2000-12-20 00:00:00

abstract：:Here, we demonstrate that interleukin-1β (IL-1β) contributes to the γ-ionizing radiation (IR)-induced increase of migration/invasion in A549 lung cancer cells, and that this occurs via RIP1 upregulation. We initially observed that the protein expression and secreted concentration of IL-1β were increased upon exposure ...

journal_title：Biochemical and biophysical research communications

authors： Kang AR,Cho JH,Lee NG,Kwon JH,Song JY,Hwang SG,Jung IS,Kim JS,Um HD,Oh SC,Park JK

更新日期：2021-01-01 00:00:00

abstract：:We examined the role of ras proteins in mitogenesis and proliferation of A10 smooth muscle cells. An assay was developed in which a dominant negative ras gene could be transiently expressed in vascular smooth muscle cells. As opposed to cells transfected with a control plasmid, those transfected with a dominant negati...

journal_title：Biochemical and biophysical research communications

authors： Irani K,Herzlinger S,Finkel T

更新日期：1994-08-15 00:00:00

abstract：:MicroRNA-125a exhibits an antiproliferative activity and is downregulated in several types of tumors, including hepatocellular carcinoma where it targets sirtuin-7, matrix metalloproteinase-11, and c-Raf. Another target of miR-125a is Lin28, a pluripotency factor that is generally undetectable in differentiated cells ...

journal_title：Biochemical and biophysical research communications

authors： Panella M,Mosca N,Di Palo A,Potenza N,Russo A

更新日期：2018-06-07 00:00:00

abstract：:The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Recombinant human EPO (rhEPO) is therefore used to treat anemia in cancer patients. However, clinical trials have indicated that rhEPO treatment might promote tumor progression and has a negative effect on patient s...

journal_title：Biochemical and biophysical research communications

authors： Reinbothe S,Larsson AM,Vaapil M,Wigerup C,Sun J,Jögi A,Neumann D,Rönnstrand L,Påhlman S

更新日期：2014-02-28 00:00:00

abstract：:In this study, we examined the effect of CLA isomers in preventing age-associated muscle loss and the mechanisms underlying this effect, using 12-months-old C57BL/6 mice fed 10% corn oil (CO) or a diet supplemented with 0.5% c9t11-CLA, t10c12-CLA, or c9t11-CLA+t10c12-CLA (CLA-mix) for 6months. Both t10c12-CLA and CLA-...

journal_title：Biochemical and biophysical research communications

authors： Rahman M,Halade GV,El Jamali A,Fernandes G

更新日期：2009-06-12 00:00:00