A putative prokaryote voltage-gated Ca(2+) channel with only one 6TM motif per subunit.

abstract：:A variant cytochrome P450 11 beta-hydroxylase/aldosterone synthase cDNA (CYP11B2) clone, pALDO-4, was isolated and sequenced from a rat zona glomerulosa cDNA library. This clone contains a 1521 bp open reading frame coding for a 506 amino acid residue protein which has a 30 amino acid extension peptide which is 6 resi...

journal_title：Biochemical and biophysical research communications

authors： Zhou M,Gomez-Sanchez CE

更新日期：1993-07-15 00:00:00

abstract：:Labelling of membrane phospholipids with 32P was compared in rat and rabbit aorta under basal conditions and during alpha 1-receptor stimulation. Incorporation of 32P proceeded at a significantly higher rate in rat tissue. The ratio of basal labelling following 30 min of incubation for rat/rabbit arteries was 4.8 for ...

journal_title：Biochemical and biophysical research communications

authors： Campbell MD,Danthuluri NR,Deth RC

更新日期：1986-12-30 00:00:00

abstract：:Actin depolymerization through Rho GTPases or exogenous mechanical tension has been suggested as a key determinant for the formation of astrocyte stellation. Rho GTPases function as switching molecules to converge both extracellular and intracellular signals in regulation of cytoskeletal organization. Their involvemen...

journal_title：Biochemical and biophysical research communications

authors： Chen CJ,Liao SL,Huang YS,Chiang AN

更新日期：2005-01-28 00:00:00

abstract：:Cell cycle variations in ADP-ribosylation of nuclear scaffold proteins were determined. Nuclei of synchronized cells were isolated and labeled with [32P]NAD before nuclear scaffolds were obtained by digestion of DNA with DNase I and extraction of proteins with 2M NaCl. Autoradiograms revealed the three groups of "lami...

journal_title：Biochemical and biophysical research communications

authors： Adolph KW,Song MK

更新日期：1985-01-31 00:00:00

abstract：:Laminin is a potent stimulator of neurite outgrowth in rat pheochromocytoma (PC12) cells. Here, we investigated the role of protein kinase C (PKC) in the mechanism of laminin-mediated neurite outgrowth in PC12 cells. Phorbol ester activators of PKC have been shown to have divergent effects on laminin-mediated neurite ...

journal_title：Biochemical and biophysical research communications

authors： Weeks BS,Wilson PJ,Heffernan CC,Ahmad A,Mahadeo K

更新日期：1999-03-05 00:00:00

abstract：:In this study we have continuously measured real-time production of nitric oxide (NO) in the isolated, perfused rat lung by using an NO monitor (model NO-501, Inter Medical Co., Nagoya, Japan) with an NO-selective resin microsensor. A stable NO response was obtained when the sensor was placed in the pulmonary artery o...

journal_title：Biochemical and biophysical research communications

authors： Wang D,Hsu K,Hwang CP,Chen HI

更新日期：1995-03-28 00:00:00

abstract：:Selected purinoceptor modulators were previously shown to prevent glutamate-evoked cytotoxicity in cerebellar granule neurons. In the same cellular system, we now identify and characterize the presence of P2 receptors. The binding of [3H]ATP to membranes of cerebellar granule neurons grows monotonically as a function ...

journal_title：Biochemical and biophysical research communications

authors： Merlo D,Volonté C

更新日期：1996-08-23 00:00:00

abstract：:The CCAAT/enhancer binding proteins (C/EBPs) and the peroxisome proliferator-activated receptors (PPARs) together regulate adipogenesis. The current work uses co-transfection studies to examine the C/ EBP dependence of PPAR gamma 2 transcription. Both C/ EBP alpha and C/EBP delta expression vectors activated transcrip...

journal_title：Biochemical and biophysical research communications

authors： Clarke SL,Robinson CE,Gimble JM

更新日期：1997-11-07 00:00:00

abstract：AIMS:New Zealand obese (NZO) mice exhibit a polygenic syndrome of obesity, insulin resistance, and hypercholesterolemia that resembles the human metabolic syndrome. This study was performed in order to locate genes responsible for elevated serum cholesterol and to compare their effects under a standard and high fat die...

journal_title：Biochemical and biophysical research communications

authors： Giesen K,Plum L,Kluge R,Ortlepp J,Joost HG

更新日期：2003-05-16 00:00:00

abstract：:Kinetic studies of the reduction of Pseudomonas aeruginosa ferricytochrome c551 by Fe(EDTA)2- have been made. The reaction was found to follow a second-order rate law: k 4.2 x 10(3) M(-1) s(-1) [25 degrees, micro0.1 M, pH 7.0 (phosphate)]; deltaH+/+ 3.2 kcal/ mol; AS+/+ -30 cal/mol-deg. The electrostatics-corrected se...

journal_title：Biochemical and biophysical research communications

authors： Coyle CL,Gray HB

更新日期：1976-12-20 00:00:00

abstract：:Keratins are a family of structurally related proteins that form the intermediate filament cytoskeleton in epithelial cells. Mutations in K1 and K5 result in the autosomal dominant disorders epidermolytic hyperkeratosis/bullous congenital ichthyosiform erythroderma and epidermolysis bullosa simplex, respectively. Most...

journal_title：Biochemical and biophysical research communications

authors： Whittock NV,Eady RA,McGrath JA

更新日期：2000-07-21 00:00:00

abstract：:The fibroblast growth factors (FGFs) are involved in hematopoiesis and tumorigenesis. However, little is known about the contribution of the FGFs identified within the past 10 years to leukemogenesis. To elucidate whether these FGFs (FGF-8, -9, -10, -11, -12, -13, -14, -16, -17, -18, -19, -20, and -21) are expressed i...

journal_title：Biochemical and biophysical research communications

authors： Nezu M,Tomonaga T,Sakai C,Ishii A,Itoga S,Nishimura M,Matsuo Y,Tagawa M,Nomura F

更新日期：2005-09-30 00:00:00

abstract：:The expression of tenascin (Tn), an extracellular matrix glycoprotein, was analyzed in the human small intestine. Three major oligomeric forms of intestinal Tn (320 kDa, 220 kDa and 200 kDa) were identified in both the fetus and the adult. The intestinal 200 kDa form was not found expressed by intestinal mesenchymal c...

journal_title：Biochemical and biophysical research communications

authors： Beaulieu JF,Jutras S,Kusakabe M,Perreault N

更新日期：1993-05-14 00:00:00

abstract：:Traumatic spinal cord injury (SCI) is a major cause of death and lifelong disability in the world. However, the pathological process of SCI has not been fully understood. F-box/WD repeat-containing protein 5 (FBXW5), a subunit of the SCF-type E3 ubiquitin ligase complex, plays an essential role in regulating various p...

journal_title：Biochemical and biophysical research communications

authors： Zhao P,Chao W,Li W

更新日期：2019-06-25 00:00:00

abstract：:We report the modulatory effects of estrogen on release of endothelium-derived relaxing factors (EDRFs) in a human endothelial cell line, EA.hy926. Using bioassay, we showed that EA.hy926 released EDRF including nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF) measured by relaxation of pre-contr...

journal_title：Biochemical and biophysical research communications

authors： Rahimian R,Chan L,Goel A,Poburko D,van Breemen C

更新日期：2004-09-17 00:00:00

abstract：:Th2 cell differentiation is critically influenced by transcription factor GATA-3 and by various cis-acting elements including enhancers, silencers and a locus control region (LCR) in the Th2 cytokine locus. Th2 LCR-deficient Th2 cells completely lost the expression of GATA-3 and the phosphorylation of STAT6. Histone 3...

journal_title：Biochemical and biophysical research communications

authors： Hwang SS,Kim K,Lee GR

更新日期：2011-07-15 00:00:00

abstract：:The late endosomal marker Rab7 has been long believed to be absent from the phagosome containing Mycobacterium tuberculosis (M.tb) in macrophage, but the detail kinetics remains elusive. Here, we found that Rab7 is transiently recruited to and subsequently released from M.tb phagosomes. For further understanding of th...

journal_title：Biochemical and biophysical research communications

authors： Seto S,Matsumoto S,Ohta I,Tsujimura K,Koide Y

更新日期：2009-09-18 00:00:00

abstract：:c-Src kinases and p21 Ras are known to be implicated in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated signal transduction. However, the effects of TCDD on the molecular interaction of adaptor complex in the protein tyrosine kinase signaling cascade have not been reported. The present study is designed to clarify...

journal_title：Biochemical and biophysical research communications

authors： Park R,Kim DH,Kim MS,So HS,Chung HT,Kwon KB,Ryu DG,Kim BR

更新日期：1998-12-30 00:00:00

abstract：:In the present report we analyze by reverse transcription (RT) and polymerase chain reaction (PCR) the expression of vasoactive intestinal peptide receptors (VIP-R) in rat thymocytes and peripheral T and B lymphocytes. We have obtained a specific VIP-R cDNA product of 311 bp identical in size to that obtained from lun...

journal_title：Biochemical and biophysical research communications

authors： Gomariz RP,Garrido E,Leceta J,Martinez C,Abalo R,Delgado M

更新日期：1994-09-30 00:00:00

abstract：:Long non-coding RNAs (LncRNAs) have played very important roles in the malignancy behaviors of hepatocellular carcinoma (HCC). Linc-cdh4-2 (TCONS_00027978) is a novel LncRNA that has been identified in HCC tissues from our previous study. Overexpression of linc-cdh4-2 in HCC cell lines (SK-Hep-1 and Huh7) significantl...

journal_title：Biochemical and biophysical research communications

authors： Gao Y,Wang G,Zhang C,Lin M,Liu X,Zeng Y,Liu J

更新日期：2016-11-18 00:00:00

abstract：:Legionella pneumophila is a flagellated pathogenic bacterium that causes atypical pneumonia called Legionnaires' disease. The flagellum plays a key role in the pathogenesis of L. pneumophila in the host. The protein FlgL forms a junction between the flagellar hook and filament and has been reported to elicit the host ...

journal_title：Biochemical and biophysical research communications

authors： Song WS,Hong HJ,Yoon SI

更新日期：2020-08-20 00:00:00

abstract：:The effect of platelet release products on cytosolic calcium [( Ca++]i) was examined by monitoring the fluorescence of chick embryonic heart cells loaded with the fluorescent calcium indicator indo-1 AM. Cell free filtrate of platelet release products was obtained from rabbit platelets activated with thrombin or colla...

journal_title：Biochemical and biophysical research communications

authors： Chien WW,Mohabir R,Newman D,Leung LL,Clusin WT

更新日期：1990-08-16 00:00:00

abstract：:The retinoid-related orphan receptor gamma (RORgamma) has been shown to function as a positive regulator of transcription in many cell lines. Transcriptional activation by nuclear receptors involves recruitment of co-activators that interact with receptors through their LXXLL motifs (NR box). In this study, we analyze...

journal_title：Biochemical and biophysical research communications

authors： Kurebayashi S,Nakajima T,Kim SC,Chang CY,McDonnell DP,Renaud JP,Jetten AM

更新日期：2004-03-19 00:00:00

abstract：:Dopamine (DA) and related catechols may contribute to selective degeneration of dopaminergic neurons in the substantia nigra in Parkinson's disease. To investigate whether DA induces apoptosis of dopaminergic neurons, we characterized the effects of various concentrations of exogenous DA on a substantia nigra/neurobla...

journal_title：Biochemical and biophysical research communications

authors： Zhang J,Price JO,Graham DG,Montine TJ

更新日期：1998-07-30 00:00:00

abstract：:Two types of cDNA clones of protein phosphatase 2A beta, PP-2A beta L and PP-2A beta S, were isolated from a rat testis cDNA library. PP-2A beta L was 1.8 kb in length and corresponded to the 2.0 kb mRNA that is the major species expressed in somatic tissues. PP-2A beta S was 1.3 kb in length and corresponded to the 1...

journal_title：Biochemical and biophysical research communications

authors： Sasaki K,Kitagawa Y,Shima H,Irino S,Sugimura T,Nagao M

更新日期：1990-07-16 00:00:00

abstract：:A biotin-polyethylene glycol (PEG)-epidermal growth factor (EGF) conjugate was immobilized onto the surface of avidin-modified adenovirus (ADV-Avi) via biotin-avidin interaction to deliver ADV specifically to EGF receptor over-expressing cancer cells. ADV-Avi/biotin-PEG-EGF complexes showed greatly enhanced intracellu...

journal_title：Biochemical and biophysical research communications

authors： Park JW,Mok H,Park TG

更新日期：2008-02-15 00:00:00

abstract：:Dengue Virus (DENV) infection is an important mosquito-borne viral disease and its clinical symptoms range from a predominantly febrile disease, dengue fever (DF), to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Increased levels of cytokines - the so-called 'cytokine storm', contribute to the pathog...

journal_title：Biochemical and biophysical research communications

authors： Suttitheptumrong A,Khunchai S,Panaampon J,Yasamut U,Morchang A,Puttikhunt C,Noisakran S,Haegeman G,Yenchitsomanus PT,Limjindaporn T

更新日期：2013-06-28 00:00:00

abstract：:In this study, we investigated hybrid and non-hybrid actomyosin models including key contractile proteins: actin, myosin, and tropomyosin. These proteins were isolated from the rabbit skeletal muscle and the catch muscle of the mussel Crenomytilus grayanus. Our results confirmed literature data on an unusual ability o...

journal_title：Biochemical and biophysical research communications

authors： Shelud'ko NS,Vyatchin IG,Lazarev SS,Shevchenko UV

更新日期：2015-08-21 00:00:00

abstract：:A novel inhibitory receptor of immunoglobin superfamily (IgSF), IgSF member 13 (IgSF13), has been identified from human dendritic cells (DC). IgSF13 is a type I transmembrane protein containing an N-terminal signal peptide, a extracellular region with a single Ig V-like domain, a transmembrane region, and a cytoplasmi...

journal_title：Biochemical and biophysical research communications

authors： Sui L,Li N,Liu Q,Zhang W,Wan T,Wang B,Luo K,Sun H,Cao X

更新日期：2004-07-02 00:00:00

abstract：:3q21q26 syndrome, an acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) with chromosomal translocations or inversions between the bands 3q21 and 3q26, is frequently associated with dysmegakaryocytopoiesis and increased platelet counts at the initial diagnosis. Since the EVI1 gene at 3q26 is transcriptional...

journal_title：Biochemical and biophysical research communications

authors： Shimizu S,Nagasawa T,Katoh O,Komatsu N,Yokota J,Morishita K

更新日期：2002-04-05 00:00:00