Abstract：
:Although there is substantial evidence that, in animals, male-inherited neutral DNA evolves at a higher rate than female-inherited DNA, the relative evolutionary rate of male- versus female-inherited DNA has not been investigated in plants. We compared the substitution rates at neutral sites of maternally and paternally inherited organellar DNA in gymnosperms. The analysis provided substantial support for the presence of a higher evolutionary rate in both the mitochondrial and chloroplastidial DNA when the organelle was inherited paternally than when inherited maternally. These results suggest that, compared with eggs, sperm tend to carry a greater number of mutations in mitochondrial and chloroplastidial DNA. The existence of a male mutation bias in plants is remarkable because, unlike animals, the germ-lines are not separated from the somatic cells throughout an individual's lifetime. The data therefore suggest that even a brief period of male and female germ-line separation can cause gender-specific mutation rates. These results are the first to show that, at least in some species, germ-lines influence the number of mutations carried in the gametes. Possible causes of male mutation bias in plants are discussed.
journal_name
Mol Biol Evoljournal_title
Molecular biology and evolutionauthors
Whittle CA,Johnston MOdoi
10.1093/oxfordjournals.molbev.a004151subject
Has Abstractpub_date
2002-06-01 00:00:00pages
938-49issue
6eissn
0737-4038issn
1537-1719journal_volume
19pub_type
杂志文章abstract：:A cDNA that encodes the heart-type lactate dehydrogenase (LDH-B) from the teleost fish Fundulus heteroclitus was cloned and sequenced. The protein encoded by the cDNA was analyzed in relation to 13 LDH proteins from a variety of taxa. One of the deductions from this analysis is that LDH-B proteins have residues in the...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040559
更新日期：1989-07-01 00:00:00
abstract：:Proteins evolve not only through point mutations but also by insertion and deletion events, which affect the length of the protein. It is well known that such indel events most frequently occur in surface-exposed loops. However, detailed analysis of indel events in distantly related and fast-evolving proteins is hampe...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/mst157
更新日期：2013-12-01 00:00:00
abstract：:Molecular clocks are routinely tested for linearity using a relative rate test and routinely calibrated against the geological time scale using a single or average paleontologically determined time of divergence between living taxa. The relative rate test is a test of parallel rate equality, not a test of rate constan...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040391
更新日期：1986-05-01 00:00:00
abstract：:We examined microsatellite variation in two diploid, outcrossing relatives of Arabidopsis thaliana, Arabis petraea and Arabis lyrata. The primer sequences were derived from A. thaliana. About 50% (14 loci) of the A. thaliana primers could successfully amplify microsatellites in the related species. Analysis of microsa...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a025758
更新日期：1997-03-01 00:00:00
abstract：:For populations to maintain optimal fitness, harmful mutations must be efficiently purged from the genome. Yet, under circumstances that diminish the effectiveness of natural selection, such as the process of plant and animal domestication, deleterious mutations are predicted to accumulate. Here, we compared the load ...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msv106
更新日期：2015-09-01 00:00:00
abstract：:Photosystem II, the water oxidizing enzyme, altered the course of evolution by filling the atmosphere with oxygen. Here, we reconstruct the origin and evolution of water oxidation at an unprecedented level of detail by studying the phylogeny of all D1 subunits, the main protein coordinating the water oxidizing cluster...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msv024
更新日期：2015-05-01 00:00:00
abstract：:Plasmodium vivax in southern Mexico exhibits different infectivities to 2 local mosquito vectors, Anopheles pseudopunctipennis and Anopheles albimanus. Previous work has tied these differences in mosquito infectivity to variation in the central repeat motif of the malaria parasite's circumsporozoite (csp) gene, but su...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msn073
更新日期：2008-06-01 00:00:00
abstract：:We performed a genealogical analysis of the ionotropic glutamate receptor (iGluR) gene family, which includes the animal iGluRs and the newly isolated glutamate receptor-like genes (GLR) of plants discovered in Arabidopsis. Distance measures firmly placed the plant GLR genes within the iGluR clade as opposed to other ...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a026167
更新日期：1999-06-01 00:00:00
abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) recently emerged in domestic pigs of Western Europe and North America. Although time of emergence was identical on the two continents, genetic composition was markedly different with a clear geographical subtype structure, indicating that subtypes diverged in...
journal_title：Molecular biology and evolution
pub_type： 评论,信件
doi：10.1093/molbev/msi208
更新日期：2005-11-01 00:00:00
abstract：:Multiple haplotypes from each of three nuclear loci were isolated and sequenced from geographic populations of the American oyster, Crassostrea virginica. In tests of alternative phylogeographic hypotheses for this species, nuclear gene genealogies constructed for these haplotypes were compared to one another, to a mi...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a025908
更新日期：1998-02-01 00:00:00
abstract：:Due to its speed, the distance approach remains the best hope for building phylogenies on very large sets of taxa. Recently (R. Desper and O. Gascuel, J. Comp. Biol. 9:687-705, 2002), we introduced a new "balanced" minimum evolution (BME) principle, based on a branch length estimation scheme of Y. Pauplin (J. Mol. Evo...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msh049
更新日期：2004-03-01 00:00:00
abstract：:The detection of selection, both positive and negative, acting on a DNA sequence or class of nucleotide sites requires comparison with a reference sequence that is unaffected by selection. In Drosophila, recent findings of widespread selective constraint, as well as adaptive evolution, in both coding and noncoding reg...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msq046
更新日期：2010-06-01 00:00:00
abstract：:There are three common alleles (A, B, and O) at the human ABO blood group locus. We compared nucleotide sequences of these alleles, and relatively large numbers of nucleotide differences were found among them. These differences correspond to the divergence time of at least a few million years, which is unusually large...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a025776
更新日期：1997-04-01 00:00:00
abstract：:Single-copy nuclear DNAs (scnDNAs) of eight species of arvicoline and six species of murine rodents were compared using DNA-DNA hybridization. The branching pattern derived from the DNA comparisons is congruent with the fossil evidence and supported by comparative biochemical, chromosomal, and morphological studies. T...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040444
更新日期：1987-05-01 00:00:00
abstract：:A major theoretical consequence of selection at a locus is the genetic hitchhiking of linked sites (selective sweep). The extent of hitchhiking around a gene is related to the strength of selection and the rate of recombination, with its impact diminishing with distance from the selected site. At the Rop-1 locus of th...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msr006
更新日期：2011-06-01 00:00:00
abstract：:Chromosomal DNA from 23 closely related, pathogenic strains of Escherichia coli was digested and probed for the insertion sequences IS1, IS2, IS4, IS5, and IS30. Under the assumption that elements residing in DNA restriction fragments of the same apparent length are identical by descent, parsimony analysis of these ch...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040531
更新日期：1989-01-01 00:00:00
abstract：:From the stirodont Arbacia lixula we determined the sequence of 5,127 nucleotides of mitochondrial DNA (mtDNA) encompassing 18 tRNAs, two complete coding genes, parts of three other coding genes, and part of the 12S ribosomal RNA (rRNA). The sequence confirms that the organization of mtDNA is conserved within echinoid...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040661
更新日期：1991-07-01 00:00:00
abstract：:This review explores features of the origin and evolution of colicins in Escherichia coli. First, the evolutionary relationships of 16 colicin and colicin-related proteins are inferred from amino acid and DNA sequence comparisons. These comparisons are employed to detail the evolutionary mechanisms involved in the ori...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040081
更新日期：1993-11-01 00:00:00
abstract：:To investigate the potential importance of gene duplication in D. melanogaster accessory gland protein (Acp) gene evolution we carried out a computational analysis comparing annotated D. melanogaster Acp genes to the entire D. melanogaster genome. We found that two known Acp genes are actually members of small multige...
journal_title：Molecular biology and evolution
pub_type： 信件
doi：10.1093/molbev/msh195
更新日期：2004-09-01 00:00:00
abstract：:Male reproductive fitness is strongly affected by seminal fluid. In addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. In mammals, the male reproductive tract shows a striking degree of compartmentalization,...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msp094
更新日期：2009-08-01 00:00:00
abstract：:Seminal fluid proteins (SFPs) mediate an array of postmating reproductive processes that influence fertilization and fertility. As such, it is widely held that SFPs may contribute to postmating, prezygotic reproductive barriers between closely related taxa. We investigated seminal fluid (SF) diversification in a recen...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msz235
更新日期：2020-02-01 00:00:00
abstract：:The proportion of functional sequence in the human genome is currently a subject of debate. The most widely accepted figure is that approximately 5% is under purifying selection. In Drosophila, estimates are an order of magnitude higher, though this corresponds to a similar quantity of sequence. These estimates depend...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msp299
更新日期：2010-04-01 00:00:00
abstract：:Nonsense-mediated decay (NMD) pathways for detection and degradation of transcripts containing premature termination (stop) codons (PTCs) are ubiquitous among the eukaryotes. NMD uses the presence of a second signal downstream of a termination codon to distinguish a PTC from a true stop codon. In mammals and perhaps o...
journal_title：Molecular biology and evolution
pub_type： 信件
doi：10.1093/molbev/msm010
更新日期：2007-04-01 00:00:00
abstract：:We determine the phylogenetic backbone of the East Asian mtDNA tree by using published complete mtDNA sequences and assessing both coding and control region variation in 69 Han individuals from southern China. This approach assists in the interpretation of published mtDNA data on East Asians based on either control re...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a003996
更新日期：2002-10-01 00:00:00
abstract：:DNA supercoiling is the master function that interconnects chromosome structure and global gene transcription. This function has recently been shown to be under strong selection in Escherichia coli. During the evolution of 12 initially identical populations propagated in a defined environment for 20,000 generations, p...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msq099
更新日期：2010-09-01 00:00:00
abstract：:Finding correct species relationships using phylogeny reconstruction based on molecular data is dependent on several empirical and technical factors. These include the choice of DNA sequence from which phylogeny is to be inferred, the establishment of character homology within a sequence alignment, and the phylogeny a...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a026285
更新日期：2000-12-01 00:00:00
abstract：:Viral genome integration provides a complex route to biological innovation that has rarely but repeatedly occurred in one of the most diverse lineages of organisms on the planet, parasitoid wasps. We describe a novel endogenous virus in braconid wasps derived from pathogenic alphanudiviruses. Limited to a subset of th...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/msy148
更新日期：2018-10-01 00:00:00
abstract：:Partial 18S rRNA sequence of the nemertine Cerebratulus lacteus was obtained and compared with those of coelomate metazoans and acoelomate platyhelminths to test whether nemertines share a most recent common ancestor with the platyhelminths, as traditionally has been implied, or whether nemertines lie within a protost...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a040716
更新日期：1992-03-01 00:00:00
abstract：:Current sequencing methods produce large amounts of data, but genome assemblies constructed from these data are often fragmented and incomplete. Incomplete and error-filled assemblies result in many annotation errors, especially in the number of genes present in a genome. This means that methods attempting to estimate...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/molbev/mst100
更新日期：2013-08-01 00:00:00
abstract：:The evolution of DNA base composition evolution is simplified to a six-parameter model when there are no strand biases for mutation and selection. We analyzed the dynamics of this model with special attention to the influence of a change in substitution rates. The G + C content of the DNA sequence tends to an equilibr...
journal_title：Molecular biology and evolution
pub_type： 杂志文章
doi：10.1093/oxfordjournals.molbev.a026156
更新日期：1999-06-01 00:00:00
