Local adaptation and vector-mediated population structure in Plasmodium vivax malaria.

abstract：:The little fire ant, Wasmannia auropunctata, displays a peculiar breeding system polymorphism. Classical haplo-diploid sexual reproduction between reproductive individuals occurs in some populations, whereas, in others, queens and males reproduce clonally. Workers are produced sexually and are sterile in both clonal a...

journal_title：Molecular biology and evolution

authors： Rey O,Loiseau A,Facon B,Foucaud J,Orivel J,Cornuet JM,Robert S,Dobigny G,Delabie JH,Mariano Cdos S,Estoup A

更新日期：2011-09-01 00:00:00

abstract：:A recent investigation found evidence that the transition of Arabidopsis thaliana from ancestral self-incompatibility (SI) to full self-compatibility occurred very recently and suggested that this occurred through a selective fixation of a nonfunctional allele (PsiSCR1) at the SCR gene, which determines pollen specifi...

journal_title：Molecular biology and evolution

authors： Bechsgaard JS,Castric V,Charlesworth D,Vekemans X,Schierup MH

更新日期：2006-09-01 00:00:00

abstract：:We present a method for pairwise Assessment of Nonfunctionalization Times (pANT) in processed pseudogenes. Contrary to existing methods for estimating nonfunctionalization times, pANT utilizes previously calculated probabilities of nucleotide substitution as explicit rate measurements, rather than assume that the subs...

journal_title：Molecular biology and evolution

authors： Fleishman SJ,Dagan T,Graur D

更新日期：2003-11-01 00:00:00

abstract：:Several new families of DNA transposons were identified by computer-assisted searches in a wide range of animal species that includes nematodes, flat worms, mosquitoes, sea squirt, zebrafish, and humans. Many of these elements have coding capacity for transposases, which are related to each other and to those encoded ...

journal_title：Molecular biology and evolution

authors： Feschotte C

更新日期：2004-09-01 00:00:00

abstract：:We describe a stochastic birth-and-death model of evolution of horizontally transferred genes in microbial populations. The model is a generalization of the stochastic model described by Berg and Kurland and includes five parameters: the rate of mutational inactivation, selection coefficient, invasion rate (i.e., rate...

journal_title：Molecular biology and evolution

authors： Novozhilov AS,Karev GP,Koonin EV

更新日期：2005-08-01 00:00:00

abstract：:Since the discovery of ING1 class II tumor suppressors in 1996, five different ING genes (ING1 to ING5) encoding proteins with highly conserved plant homeodomain (PHD) motifs and several splicing isoforms of the ING1 and ING2 gene have been identified. The ING family functions in DNA repair and apoptosis in response t...

journal_title：Molecular biology and evolution

authors： He GH,Helbing CC,Wagner MJ,Sensen CW,Riabowol K

更新日期：2005-01-01 00:00:00

abstract：:Selection on codon usage bias is well documented in a number of microorganisms. Whether codon usage is also generally shaped by natural selection in large organisms, despite their relatively small effective population size (Ne), is unclear. In animals, the population genetics of codon usage bias has only been studied ...

journal_title：Molecular biology and evolution

authors： Galtier N,Roux C,Rousselle M,Romiguier J,Figuet E,Glémin S,Bierne N,Duret L

更新日期：2018-05-01 00:00:00

abstract：:Models of codon evolution have attracted particular interest because of their unique capabilities to detect selection forces and their high fit when applied to sequence evolution. We described here a novel approach for modeling codon evolution, which is based on Kronecker product of matrices. The 61 × 61 codon substit...

journal_title：Molecular biology and evolution

authors： Zaheri M,Dib L,Salamin N

更新日期：2014-09-01 00:00:00

abstract：:A novel family of non-long-terminal-repeat (non-LTR) retrotransposons, named MosquI, was discovered in the yellow fever mosquito, Aedes aegypti. There were approximately 14 copies of MosquI in the A. aegypti genome. Four of the five analyzed MosquI elements were truncated at the 5' ends while one of them, MosquI-Aa2, ...

journal_title：Molecular biology and evolution

authors： Tu Z,Hill JJ

更新日期：1999-12-01 00:00:00

abstract：:Approximately 100 strains derived from natural populations of Drosophila melanogaster were tested for the presence or absence of P-element sequences by using two molecular probes derived from internal regions of a full-sized P element. Strains that had been collected from several continents at varying times during the...

journal_title：Molecular biology and evolution

authors： Anxolabéhère D,Kidwell MG,Periquet G

更新日期：1988-05-01 00:00:00

abstract：:Pathogen-mediated balancing selection is regarded as a key driver of host immunogenetic diversity. A hallmark for balancing selection in humans is the heterozygote advantage at genes of the human leukocyte antigen (HLA), resulting in improved HIV-1 control. However, the actual mechanism of the observed heterozygote ad...

journal_title：Molecular biology and evolution

authors： Arora J,Pierini F,McLaren PJ,Carrington M,Fellay J,Lenz TL

更新日期：2020-03-01 00:00:00

abstract：:Single-copy nuclear DNAs (scnDNAs) of eight species of arvicoline and six species of murine rodents were compared using DNA-DNA hybridization. The branching pattern derived from the DNA comparisons is congruent with the fossil evidence and supported by comparative biochemical, chromosomal, and morphological studies. T...

journal_title：Molecular biology and evolution

authors： Catzeflis FM,Sheldon FH,Ahlquist JE,Sibley CG

更新日期：1987-05-01 00:00:00

abstract：:Complex metazoan bodies require cell-to-cell communication for development, a process often mediated by signaling molecules binding to specific receptors. Relatively few signaling pathways have been recruited during evolution to build multicellular animals from unicellular zygotes. Of these few signaling pathways, one...

journal_title：Molecular biology and evolution

authors： Bertrand S,Iwema T,Escriva H

更新日期：2014-02-01 00:00:00

abstract：:Snake venom gene evolution has been studied intensively over the past several decades, yet most previous studies have lacked the context of complete snake genomes and the full context of gene expression across diverse snake tissues. We took a novel approach to studying snake venom evolution by leveraging the complete ...

journal_title：Molecular biology and evolution

authors： Reyes-Velasco J,Card DC,Andrew AL,Shaney KJ,Adams RH,Schield DR,Casewell NR,Mackessy SP,Castoe TA

更新日期：2015-01-01 00:00:00

abstract：:Multiple kelch13 alleles conferring artemisinin resistance (ART-R) are currently spreading through Southeast Asian malaria parasite populations, providing a unique opportunity to observe an ongoing soft selective sweep, investigate why resistance alleles have evolved multiple times and determine fundamental population...

journal_title：Molecular biology and evolution

authors： Anderson TJ,Nair S,McDew-White M,Cheeseman IH,Nkhoma S,Bilgic F,McGready R,Ashley E,Pyae Phyo A,White NJ,Nosten F

更新日期：2017-01-01 00:00:00

abstract：:Recent studies of mitochondrial DNA (mtDNA) variation in mammals and Drosophila have shown an excess of amino acid variation within species (replacement polymorphism) relative to the number of silent and replacement differences fixed between species. To examine further this pattern of nonneutral mtDNA evolution, we pr...

journal_title：Molecular biology and evolution

authors： Rand DM,Kann LM

更新日期：1996-07-01 00:00:00

abstract：:Two recent studies have presented conflicting views on variation present within the 294 base third domain of the 12S rRNA gene in the genus Drosophila, and in D. pseudoobscura in particular. One study suggested that this gene is highly invariant across the genus, while another recovered 22 distinct haplotypes from 22 ...

journal_title：Molecular biology and evolution

authors： Noor MA,Larkin JC

更新日期：2000-06-01 00:00:00

abstract：:Convergent and parallel amino acid substitutions in protein evolution, collectively referred to as molecular convergence here, have small probabilities under neutral evolution. For this reason, molecular convergence is commonly viewed as evidence for similar adaptations of different species. The surge in the number of...

journal_title：Molecular biology and evolution

authors： Zou Z,Zhang J

更新日期：2015-08-01 00:00:00

abstract：:A combination of three independent biological features, genomic organization, diagnostic amino acid sites, and rare indels, was used to elucidate the phylogeny of the vertebrate serpin (serine protease inhibitor) superfamily. A strong correlation between serpin gene families displaying (1) a conserved exon-intron patt...

journal_title：Molecular biology and evolution

authors： Ragg H,Lokot T,Kamp PB,Atchley WR,Dress A

更新日期：2001-04-01 00:00:00

abstract：:The retroid family consists of all genetic elements that encode a potential reverse transcriptase (RT). Members of this family include a diversity of eukaryotic genetic elements (viruses, transposable elements, organelle introns, and plasmids) and the retrons of prokaryotes. Some retroid elements have, in addition to ...

journal_title：Molecular biology and evolution

authors： McClure MA

更新日期：1991-11-01 00:00:00

abstract：:The mutation rate of an organism is influenced by the interaction of evolutionary forces such as natural selection and genetic drift. However, the mutation spectrum (i.e., the frequency distribution of different types of mutations) can be heavily influenced by DNA repair. Using mutation-accumulation lines of the extre...

journal_title：Molecular biology and evolution

authors： Long H,Miller SF,Williams E,Lynch M

更新日期：2018-10-01 00:00:00

abstract：:Large phylogenomics data sets require fast tree inference methods, especially for maximum-likelihood (ML) phylogenies. Fast programs exist, but due to inherent heuristics to find optimal trees, it is not clear whether the best tree is found. Thus, there is need for additional approaches that employ different search st...

journal_title：Molecular biology and evolution

authors： Nguyen LT,Schmidt HA,von Haeseler A,Minh BQ

更新日期：2015-01-01 00:00:00

abstract：:It is well known that molecular data "saturates" with increasing sequence divergence (thereby losing phylogenetic information) and that in addition the accumulation of misleading information due to chance similarities or to systematic bias may accompany saturation as well. Exploratory data analysis methods that can qu...

journal_title：Molecular biology and evolution

authors： White WT,Hills SF,Gaddam R,Holland BR,Penny D

更新日期：2007-09-01 00:00:00

abstract：:Indirect tests have detected recombination in mitochondrial DNA (mtDNA) from many animal lineages, including mammals. However, it is possible that features of the molecular evolutionary process without recombination could be incorrectly inferred by indirect tests as being due to recombination. We have identified one s...

journal_title：Molecular biology and evolution

authors： Sun S,Evans BJ,Golding GB

更新日期：2011-09-01 00:00:00

abstract：:Detecting positive selection in species with heterogeneous habitats and complex demography is notoriously difficult and prone to statistical biases. The model plant Arabidopsis thaliana exemplifies this problem: In spite of the large amounts of data, little evidence for classic selective sweeps has been found. Moreove...

journal_title：Molecular biology and evolution

authors： Huber CD,Nordborg M,Hermisson J,Hellmann I

更新日期：2014-11-01 00:00:00

abstract：:Male reproductive fitness is strongly affected by seminal fluid. In addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. In mammals, the male reproductive tract shows a striking degree of compartmentalization,...

journal_title：Molecular biology and evolution

authors： Dean MD,Clark NL,Findlay GD,Karn RC,Yi X,Swanson WJ,MacCoss MJ,Nachman MW

更新日期：2009-08-01 00:00:00

abstract：:Estimation of evolutionary distances from coding sequences must take into account protein-level selection to avoid relative underestimation of longer evolutionary distances. Current modeling of selection via site-to-site rate heterogeneity generally neglects another aspect of selection, namely position-specific amino ...

journal_title：Molecular biology and evolution

authors： Halpern AL,Bruno WJ

更新日期：1998-07-01 00:00:00

abstract：:The use of parameter-rich substitution models in molecular phylogenetics has been criticized on the basis that these models can cause a reduction both in accuracy and in the ability to discriminate among competing topologies. We have explored the relationship between nucleotide substitution model complexity and nonpar...

journal_title：Molecular biology and evolution

authors： Buckley TR,Cunningham CW

更新日期：2002-04-01 00:00:00

abstract：:Interspecific hybridization is one of the major factors leading to phylogenetic incongruence among loci, but the knowledge is still limited about the potential of each locus to introgress between species. By directly sequencing three DNA regions: chloroplast DNAs (matK gene and trnL-F noncoding region), the nuclear ri...

journal_title：Molecular biology and evolution

authors： Okuyama Y,Fujii N,Wakabayashi M,Kawakita A,Ito M,Watanabe M,Murakami N,Kato M

更新日期：2005-02-01 00:00:00

abstract：:Human histatins are a family of low-M(r), neutral to very basic, histidine-rich salivary polypeptides. They probably function as part of the nonimmune host defense system in the oral cavity. A 39-kb region of DNA containing the HIS1 and HIS2 genes was isolated from two human genomic phage libraries as a series of over...

journal_title：Molecular biology and evolution

authors： Sabatini LM,Ota T,Azen EA

更新日期：1993-05-01 00:00:00