Expression of venom gene homologs in diverse python tissues suggests a new model for the evolution of snake venom.

abstract：:A highly abundant satellite DNA comprising 17% of the Tribolium castaneum (Insecta, Coleoptera) genome was cloned and sequenced. The satellite monomer is 360 bp long, has a high A+T content of 73%, and lacks significant internal substructures. The sequence variability is 3.6%, essentially due to random distribution of...

journal_title：Molecular biology and evolution

authors： Ugarković D,Podnar M,Plohl M

更新日期：1996-10-01 00:00:00

abstract：:Debate on the adaptive origins of primates has long focused on the functional ecology of the primate visual system. For example, it is hypothesized that variable expression of short- (SWS1) and middle-to-long-wavelength sensitive (M/LWS) opsins, which confer color vision, can be used to infer ancestral activity patter...

journal_title：Molecular biology and evolution

authors： Melin AD,Wells K,Moritz GL,Kistler L,Orkin JD,Timm RM,Bernard H,Lakim MB,Perry GH,Kawamura S,Dominy NJ

更新日期：2016-04-01 00:00:00

abstract：:Estimation of population parameters for the common ancestors of humans and the great apes is important in understanding our evolutionary history. In particular, inference of population size for the human-chimpanzee common ancestor may shed light on the process by which the 2 species separated and on whether the human ...

journal_title：Molecular biology and evolution

authors： Burgess R,Yang Z

更新日期：2008-09-01 00:00:00

abstract：:Among mammals, several lineages have independently adapted to a subterranean niche and possess similar phenotypic traits for burrowing (e.g., cylindrical bodies, short limbs, and absent pinnae). Previous research on mole-rats has revealed molecular adaptations for coping with reduced oxygen, elevated carbon dioxide, a...

journal_title：Molecular biology and evolution

authors： Davies KTJ,Bennett NC,Faulkes CG,Rossiter SJ

更新日期：2018-10-01 00:00:00

abstract：:This study describes the distribution of hobo-hybridizing sequences in the genus Drosophila. Southern blot analysis of 134 species revealed that hobo sequences are limited to the melanogaster and montium subgroups of the melanogaster-species group. Of the hobo-bearing species, only D. melanogaster and two of its sibli...

journal_title：Molecular biology and evolution

authors： Daniels SB,Chovnick A,Boussy IA

更新日期：1990-11-01 00:00:00

abstract：:Full-length mariner-like elements (MLEs) were identified from both a parasitoid wasp, Ascogaster reticulatus, and its moth host, Adoxophyes honmai. MLEs were detected in two related Tortricid moths, but not in another Ascogaster species. The MLEs of A. reticulatus and A. honmai were 97.6% identical in DNA sequence. Th...

journal_title：Molecular biology and evolution

authors： Yoshiyama M,Tu Z,Kainoh Y,Honda H,Shono T,Kimura K

更新日期：2001-10-01 00:00:00

abstract：:Several authors have postulated that genetic divergence between populations could result in genomic incompatibilities that would cause an increase in transposition in their hybrids, producing secondary effects such as sterility and therefore starting a speciation process. It has been demonstrated that transposition la...

journal_title：Molecular biology and evolution

authors： Labrador M,Farré M,Utzet F,Fontdevila A

更新日期：1999-07-01 00:00:00

abstract：:A more than 10-fold difference in the specificity and catalytic efficiency for 1-naphthyl esters was measured between two allozymes of esterase-4 from Drosophila mojavensis. This difference is mainly caused by a difference in the affinity for the 1-naphthyl esters. The amino acid compositions of the allozymes are not ...

journal_title：Molecular biology and evolution

authors： Pen J,Schipper A,Rongen HA,Beintema JJ

更新日期：1986-07-01 00:00:00

abstract：:The protein tyrosine phosphatase (PTP) family plays a central role in signal transduction pathways by controlling the phosphorylation state of serine, threonine, and tyrosine residues. PTPs can be divided into dual specificity phosphatases and the classical PTPs, which can comprise of one or two phosphatase domains. W...

journal_title：Molecular biology and evolution

authors： Pils B,Schultz J

更新日期：2004-04-01 00:00:00

abstract：:Heme biosynthesis represents one of the most essential metabolic pathways in living organisms, providing the precursors for cytochrome prosthetic groups, photosynthetic pigments, and vitamin B(12). Using genomic data, we have compared the heme pathway in the diatom Thalassiosira pseudonana and the red alga Cyanidiosch...

journal_title：Molecular biology and evolution

authors： Oborník M,Green BR

更新日期：2005-12-01 00:00:00

abstract：:As human populations dispersed throughout the world, they were subjected to new selective forces, which must have led to local adaptation via natural selection and hence altered patterns of genetic variation. Yet, there are very few examples known in which such local selection has clearly influenced human genetic vari...

journal_title：Molecular biology and evolution

authors： Kayser M,Brauer S,Stoneking M

更新日期：2003-06-01 00:00:00

abstract：:Sex-biased gene expression is becoming an increasingly important way to study sexual selection at the molecular genetic level. However, little is known about the timing, persistence, and continuity of gene expression required in the creation of distinct male and female phenotypes, and even less about how sex-specific ...

journal_title：Molecular biology and evolution

authors： Mank JE,Nam K,Brunström B,Ellegren H

更新日期：2010-07-01 00:00:00

abstract：:Heterotachy is a general term to describe positions that evolve at different rates in different lineages. Heterotachy also can generally be viewed as multivariate rates-across-sites variation, which can be described as randomly drawing rates (or branch lengths) from a multivariate distribution for each branch at each ...

journal_title：Molecular biology and evolution

authors： Wu J,Susko E

更新日期：2011-05-01 00:00:00

abstract：:Phenotypic convergence is an exciting outcome of adaptive evolution, occurring when different species find similar solutions to the same problem. Unraveling the molecular basis of convergence provides a way to link genotype to adaptive phenotypes, but can also shed light on the extent to which molecular evolution is r...

journal_title：Molecular biology and evolution

authors： Mendes FK,Hahn Y,Hahn MW

更新日期：2016-12-01 00:00:00

abstract：:We examined microsatellite variation in two diploid, outcrossing relatives of Arabidopsis thaliana, Arabis petraea and Arabis lyrata. The primer sequences were derived from A. thaliana. About 50% (14 loci) of the A. thaliana primers could successfully amplify microsatellites in the related species. Analysis of microsa...

journal_title：Molecular biology and evolution

authors： van Treuren R,Kuittinen H,Kärkkäinen K,Baena-Gonzalez E,Savolainen O

更新日期：1997-03-01 00:00:00

abstract：:Whether higher-order chromatin organization is related to genome stability over evolutionary time remains elusive. We find that regions of conserved gene order across the genus Drosophila are larger if they harbor genes bound by B-type lamin (Lam) and Suppressor of Under-Replication (SUUR), two proteins located at the...

journal_title：Molecular biology and evolution

authors： Ranz JM,Díaz-Castillo C,Petersen R

更新日期：2012-01-01 00:00:00

abstract：:Plants can show long-term effects of environmental stresses and in some cases a stress "memory" has been reported to persist across generations, potentially mediated by epigenetic mechanisms. However, few documented cases exist of transgenerational effects that persist for multiple generations and it remains unclear i...

journal_title：Molecular biology and evolution

authors： Morgado L,Preite V,Oplaat C,Anava S,Ferreira de Carvalho J,Rechavi O,Johannes F,Verhoeven KJF

更新日期：2017-08-01 00:00:00

abstract：:Understanding genome and chromosome evolution is important for understanding genetic inheritance and evolution. Universal events comprising DNA replication, transcription, repair, mobile genetic element transposition, chromosome rearrangements, mitosis, and meiosis underlie inheritance and variation of living organism...

journal_title：Molecular biology and evolution

authors： Li X,Zhu C,Lin Z,Wu Y,Zhang D,Bai G,Song W,Ma J,Muehlbauer GJ,Scanlon MJ,Zhang M,Yu J

更新日期：2011-06-01 00:00:00

abstract：:Molar content of guanine plus cytosine (G + C) and optimal growth temperature (OGT) are main factors characterizing the frequency distribution of amino acids in prokaryotes. Previous work, using multivariate exploratory methods, has emphasized ascertainment of biological factors underlying variability between genomes,...

journal_title：Molecular biology and evolution

authors： Naya H,Gianola D,Romero H,Urioste JI,Musto H

更新日期：2006-01-01 00:00:00

abstract：:Phylogenetic reconstruction of the evolutionary history of closely related organisms may be difficult because of the presence of unsorted lineages and of a relatively high proportion of heterozygous sites that are usually not handled well by phylogenetic programs. Genomic data may provide enough fixed polymorphisms to...

journal_title：Molecular biology and evolution

authors： Lischer HE,Excoffier L,Heckel G

更新日期：2014-04-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) do not code for proteins but function as RNAs. Because the functions of an RNA rely on either its sequence or secondary structure, lncRNAs should be folded at least as strongly as messenger RNAs (mRNAs), which serve as messengers for translation and are generally thought to lack secondary...

journal_title：Molecular biology and evolution

authors： Yang JR,Zhang J

更新日期：2015-04-01 00:00:00

abstract：:Gene orders have been shown to be generally unstable by comprehensive analyses in several complete genomes. In this study, we examined instability of genome structures within operons, where functionally related genes are clustered. We compared gene orders of known operons obtained from Escherichia coli and Bacillus su...

journal_title：Molecular biology and evolution

authors： Itoh T,Takemoto K,Mori H,Gojobori T

更新日期：1999-03-01 00:00:00

abstract：:Discrepancies in phylogenetic trees of bacteria and archaea are often explained as lateral gene transfer events. However, such discrepancies may also be due to phylogenetic artifacts or orthology assignment problems. A first step that may help to resolve this dilemma is to estimate the extent of phylogenetic inconsist...

journal_title：Molecular biology and evolution

authors： Soria-Carrasco V,Castresana J

更新日期：2008-11-01 00:00:00

abstract：:Silks are strong protein fibers produced by a broad array of spiders and insects. The vast majority of known silks are large, repetitive proteins assembled into extended beta-sheet structures. Honeybees, however, have found a radically different evolutionary solution to the need for a building material. The 4 fibrous ...

journal_title：Molecular biology and evolution

authors： Sutherland TD,Weisman S,Trueman HE,Sriskantha A,Trueman JW,Haritos VS

更新日期：2007-11-01 00:00:00

abstract：:The plant MADS-box regulatory gene family includes several loci that control different aspects of inflorescence and floral development. Orthologs to the Arabidopsis thaliana MADS-box floral meristem genes APETALA1 and CAULIFLOWER and the floral organ identity genes APETALA3 and PISTILLATA were isolated from the congen...

journal_title：Molecular biology and evolution

authors： Lawton-Rauh AL,Buckler ES 4th,Purugganan MD

更新日期：1999-08-01 00:00:00

abstract：:Numerous studies have used indices of genetic distance between species to reconstruct evolutionary relationships and to estimate divergence time. However, the empirical relationship between molecular-based indices of genetic divergence and divergence time based on the fossil record is poorly known. To date, the result...

journal_title：Molecular biology and evolution

authors： Wayne RK,Van Valkenburgh B,O'Brien SJ

更新日期：1991-05-01 00:00:00

abstract：:Herpesviruses have been infecting and codiverging with their vertebrate hosts for hundreds of millions of years. The primate simplex viruses exemplify this pattern of virus-host codivergence, at a minimum, as far back as the most recent common ancestor of New World monkeys, Old World monkeys, and apes. Humans are the ...

journal_title：Molecular biology and evolution

authors： Wertheim JO,Smith MD,Smith DM,Scheffler K,Kosakovsky Pond SL

更新日期：2014-09-01 00:00:00

abstract：:To explore the origin of the diversity observed in natural populations, many studies have investigated the relationship between genotype and phenotype. In yeast species, especially in Saccharomyces cerevisiae, these studies are mainly conducted using recombinant offspring derived from two genetically diverse isolates,...

journal_title：Molecular biology and evolution

authors： Brion C,Caradec C,Pflieger D,Friedrich A,Schacherer J

更新日期：2020-09-01 00:00:00

abstract：:We compared the single-nucleotide polymorphisms (SNPs) in humans in 182 housekeeping and 148 tissue-specific genes. SNPs were divided into rare and common polymorphisms based on their frequencies. We found that housekeeping genes tend to be less polymorphic than tissue-specific genes for both rare and common SNPs. Usi...

journal_title：Molecular biology and evolution

authors： Zhang L,Li WH

更新日期：2005-12-01 00:00:00

abstract：:The Piwi-interacting RNA (piRNA) pathway defends animal genomes against the harmful consequences of transposable element (TE) infection by imposing small-RNA-mediated silencing. Because silencing is targeted by TE-derived piRNAs, piRNA production is posited to be central to the evolution of genome defense. We harnesse...

journal_title：Molecular biology and evolution

authors： Kelleher ES,Barbash DA

更新日期：2013-08-01 00:00:00