Abstract:
:Viral genome integration provides a complex route to biological innovation that has rarely but repeatedly occurred in one of the most diverse lineages of organisms on the planet, parasitoid wasps. We describe a novel endogenous virus in braconid wasps derived from pathogenic alphanudiviruses. Limited to a subset of the genus Fopius, this recent acquisition allows an unprecedented opportunity to examine early endogenization events. Massive amounts of virus-like particles (VLPs) are produced in wasp ovaries. Unlike most endogenous viruses of parasitoid wasps, the VLPs do not contain DNA, translating to major differences in parasitism-promoting strategies. Rapid changes include genomic rearrangement, loss of DNA processing proteins, and wasp control of viral gene expression. These events precede the full development of tissue-specific viral gene expression observed in older associations. These data indicate that viral endogenization can rapidly result in functional and evolutionary changes associated with genomic novelty and adaptation in parasitoids.
journal_name
Mol Biol Evoljournal_title
Molecular biology and evolutionauthors
Burke GR,Simmonds TJ,Sharanowski BJ,Geib SMdoi
10.1093/molbev/msy148subject
Has Abstractpub_date
2018-10-01 00:00:00pages
2463-2474issue
10eissn
0737-4038issn
1537-1719pii
5058060journal_volume
35pub_type
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