Experimental validation of the DPM Monte Carlo code using minimally scattered electron beams in heterogeneous media.

abstract：:Artifacts caused by patient breathing and movement during PET data acquisition affect image quality. Respiratory gating is commonly used to gate the list-mode PET data into multiple bins over a respiratory cycle. Non-rigid registration of respiratory-gated PET images can reduce motion artifacts and preserve count stat...

journal_title：Physics in medicine and biology

authors： Li T,Zhang M,Qi W,Asma E,Qi J

更新日期：2020-07-30 00:00:00

abstract：:Radiation therapy treatment planning requires an incorporation of uncertainties in order to guarantee an adequate irradiation of the tumor volumes. In current clinical practice, uncertainties are accounted for implicitly with an expansion of the target volume according to generic margin recipes. Alternatively, it is p...

journal_title：Physics in medicine and biology

authors： Mescher H,Ulrich S,Bangert M

更新日期：2017-09-05 00:00:00

abstract：:Following the publication of ICRU Report 50, the concepts of GTV (gross tumour volume). CTV (clinical target volume) and PTV (planning target volume) are being used in radiotherapy planning with increasing frequency. In 3D planning, the GTV (or CTV) is normally outlined by the clinician in CT or MRI slices. The PTV is...

journal_title：Physics in medicine and biology

authors： Stroom JC,Storchi PR

更新日期：1997-04-01 00:00:00

abstract：:Correct classification of cystoscopy images depends on the interpreter's experience. Bladder cancer is a common lesion that can only be confirmed by biopsying the tissue, therefore, the automatic identification of tumors plays a significant role in early stage diagnosis and its accuracy. To our best knowledge, the use...

journal_title：Physics in medicine and biology

authors： Freitas NR,Vieira PM,Lima E,Lima CS

更新日期：2018-02-02 00:00:00

abstract：:In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...

journal_title：Physics in medicine and biology

authors： Kaatee RS,Crezee J,Kanis AP,Lagendijk JJ,Levendag PC,Visser AG

更新日期：1997-06-01 00:00:00

abstract：:Single monochromator charge-coupled device (CCD) array spectroradiometers have the advantage of ease of use and speed compared with double grating instruments. Their inherently inferior stray-light rejection, however, can critically affect their accuracy in phototherapy and research-related dosimetry applications. Thi...

journal_title：Physics in medicine and biology

authors： Coleman A,Sarkany R,Walker S

更新日期：2008-09-21 00:00:00

abstract：:The measurement of beam data for dynamic wedge dosimetry requires the integration of radiation dose at points across the radiation field during the dose delivery. The different measurement techniques required when using a linear diode array to measure beam profiles and when using ionization chambers to measure depth d...

journal_title：Physics in medicine and biology

authors： Bidmead AM,Garton AJ,Childs PJ

更新日期：1995-03-01 00:00:00

abstract：:Automatic cell cycle analysis (DNA histograms) is usually performed with flow cytometry. In cases when only few cells are available, the DNA content has to be measured with a fluorescence microscope combined with sensitive camera systems (SIT, MCP, cooled CCDs) and a frame grabber for image analysis. The fluorescent c...

journal_title：Physics in medicine and biology

authors： Böcker W,Gantenberg HW,Müller WU,Streffer C

更新日期：1996-03-01 00:00:00

abstract：:Inverse treatment planning in intensity modulated particle therapy (IMPT) with scanned carbon-ion beams is currently based on the optimization of RBE-weighted dose to satisfy requirements of target coverage and limited toxicity to organs-at-risk (OARs) and healthy tissues. There are many feasible IMPT plans that meet ...

journal_title：Physics in medicine and biology

authors： Burigo LN,Ramos-Méndez J,Bangert M,Schulte RW,Faddegon B

更新日期：2019-01-04 00:00:00

abstract：:This paper describes end-to-end test procedures as the last fundamental step of medical commissioning before starting clinical operation of the MedAustron synchrotron-based pencil beam scanning (PBS) therapy facility with protons. One in-house homogeneous phantom and two anthropomorphic heterogeneous (head and pelvis)...

journal_title：Physics in medicine and biology

authors： Carlino A,Gouldstone C,Kragl G,Traneus E,Marrale M,Vatnitsky S,Stock M,Palmans H

更新日期：2018-02-26 00:00:00

abstract：:A method of computing theoretical X-ray spectra in the range 30-150 kV is presented. The theoretical spectra are compared with constant potential, high resolution spectra from a tungsten target measured with a Ge(Li) detector, for a range of target angles, tube voltage and filtrations. Above 100 kV the spectra were al...

journal_title：Physics in medicine and biology

authors： Birch R,Marshall M

更新日期：1979-05-01 00:00:00

abstract：:Dynamic radiation therapy techniques require that the treatment head setup varies in time and space during dose delivery. Examples are leaf motion in intensity modulated x-ray therapy, modulator wheel rotation in conventional proton therapy and variable magnet settings in proton beam scanning. Consequently, for Monte ...

journal_title：Physics in medicine and biology

authors： Paganetti H

更新日期：2004-03-21 00:00:00

abstract：:When dosimetric effects in time-dependent geometries are studied, usually either the results of individual three-dimensional (3D) calculations are combined or probability-based approaches are applied. These methods may become cumbersome and time-consuming if high time resolution is required or if the geometry is compl...

journal_title：Physics in medicine and biology

authors： Paganetti H,Jiang H,Trofimov A

更新日期：2005-03-07 00:00:00

abstract：:The 50-year tenure of Physics in Medicine and Biology has coincided with some of the most important developments in radiological science, including the introduction of artificial radioactivity, computers and 3D imaging into medicine. These events have profoundly influenced the development of brachytherapy. Although it...

journal_title：Physics in medicine and biology

authors： Williamson JF

更新日期：2006-07-07 00:00:00

abstract：:Reliable treatment planning of highly conformal scanned ion beam therapy demands accurate tools for the determination and characterization of the individual pencil-like beams building up the integral dose delivery and related mixed radiation field. At present, clinically practicable inverse treatment planning systems ...

journal_title：Physics in medicine and biology

authors： Parodi K,Mairani A,Brons S,Hasch BG,Sommerer F,Naumann J,Jäkel O,Haberer T,Debus J

更新日期：2012-06-21 00:00:00

abstract：:There are three ways to determine the spectrum of a clinical photon beam: direct measurement, modelling the source and reconstruction from ion-chamber measurements. We focus on reconstruction because the necessary equipment is readily available and it provides independent confirmation of source models for a given mach...

journal_title：Physics in medicine and biology

authors： Armbruster B,Hamilton RJ,Kuehl AK

更新日期：2004-11-21 00:00:00

abstract：:Prompt γ-ray imaging with a knife-edge shaped slit camera provides the possibility of verifying proton beam range in tumor therapy. Dedicated experiments regarding the characterization of the camera system have been performed previously. Now, we aim at implementing the prototype into clinical application of monitoring...

journal_title：Physics in medicine and biology

authors： Priegnitz M,Barczyk S,Nenoff L,Golnik C,Keitz I,Werner T,Mein S,Smeets J,Vander Stappen F,Janssens G,Hotoiu L,Fiedler F,Prieels D,Enghardt W,Pausch G,Richter C

更新日期：2016-11-21 00:00:00

abstract：:This paper describes a neural network (NN) regression model for relative dose computation. The input signal of the NN model includes depths and field sizes and the output is the relative dose, for example, percentage depth dose (%DD) or tissue-air ratio (TAR) in this paper. After a functional link has been created, th...

journal_title：Physics in medicine and biology

authors： Wu X,Zhu Y

更新日期：2000-04-01 00:00:00

abstract：:Noise equivalent count rate (NECR) and image noise are two different but related metrics that have been used to predict and assess image quality, respectively. The aim of this study is to investigate, using patient studies, the relationships between injected dose (ID), body mass index (BMI) and scanner type on NECR an...

journal_title：Physics in medicine and biology

authors： Chang T,Chang G,Kohlmyer S,Clark JW,Rohren E,Mawlawi OR

更新日期：2011-08-21 00:00:00

abstract：:During image-guided cancer radiation treatment, three-dimensional (3D) tumor volumetric information is important for treatment success. However, it is typically not feasible to image a patient's 3D tumor continuously in real time during treatment due to concern over excessive patient radiation dose. We present a new i...

journal_title：Physics in medicine and biology

authors： Mao S,Wu H,Sandison G,Fang S

更新日期：2017-02-21 00:00:00

abstract：:Tumour blood flow is one of the important factors limiting the efficacy of radiation therapy (hypoxic radioresistance), chemotherapy (drug delivery) and thermal therapy (heat dissipation) in treating cancer. The modification of tumour blood flow has been an area of intense investigation. In the current study, the arte...

journal_title：Physics in medicine and biology

authors： Purdie TG,Lee TY

更新日期：2003-04-07 00:00:00

abstract：:This study presents the first observation of shear waves induced remotely within soft tissues. It was performed through the combination of a transcranial magnetic stimulation device and a permanent magnet. A physical model based on Maxwell and Navier equations was developed. Experiments were performed on a cryogel pha...

journal_title：Physics in medicine and biology

authors： Grasland-Mongrain P,Miller-Jolicoeur E,Tang A,Catheline S,Cloutier G

更新日期：2016-03-21 00:00:00

abstract：:Knowledge of what dose-volume histograms can be expected for a previously unseen patient could increase consistency and quality in radiotherapy treatment planning. We propose a machine learning method that uses previous treatment plans to predict such dose-volume histograms. The key to the approach is the framing of d...

journal_title：Physics in medicine and biology

authors： Skarpman Munter J,Sjölund J

更新日期：2015-09-07 00:00:00

abstract：:In a previous paper the calibration of an isotropic light detector in clear media was described and validated. However, in most applications the detector is used to measure light distribution in turbid (scattering) media, that is, in tissues or tissue equivalent optical phantoms. Despite its small diameter (typically ...

journal_title：Physics in medicine and biology

authors： Marijnissen JP,Star WM

更新日期：2002-06-21 00:00:00

abstract：:Magnetic Particle Imaging (MPI) is a promising medical imaging technique for visualizing the three-dimensional distribution of tracer materials, specifically iron oxide nanoparticles (IONP). The optimization of magnetic nanoparticles (MNP) plays an essential role to improve the image resolution and sensitivity of imag...

journal_title：Physics in medicine and biology

authors： Arsalani S,Loewa N,Kosch O,Radon P,Baffa O,Wiekhorst F

更新日期：2020-11-23 00:00:00

abstract：:To evaluate a commercial synthetic CT (syn-CT) software for use in prostate radiotherapy. Twenty-five prostate patients underwent CT and MR simulation scans in treatment position on a 3T MR scanner. A commercially available MR protocol was used that included a T2w turbo spin-echo sequence for soft-tissue contrast and ...

journal_title：Physics in medicine and biology

authors： Tyagi N,Fontenla S,Zhang J,Cloutier M,Kadbi M,Mechalakos J,Zelefsky M,Deasy J,Hunt M

更新日期：2017-04-21 00:00:00

abstract：:The class of non-rigid registration methods proposed in the framework of PDE-constrained large deformation diffeomorphic metric mapping is a particularly interesting family of physically meaningful diffeomorphic registration methods. Inexact Gauss-Newton-Krylov optimization has shown an excellent numerical accuracy an...

journal_title：Physics in medicine and biology

authors： Hernandez M

更新日期：2019-01-07 00:00:00

abstract：:Nanocarriers offer a promising approach to significantly improve therapeutic delivery to solid tumors as well as limit the side effects associated with anti-cancer agents. However, their relatively large size can negatively affect their ability to efficiently penetrate into more interior tumor regions, ultimately redu...

journal_title：Physics in medicine and biology

authors： Mohammadabadi A,Huynh RN,Wadajkar AS,Lapidus RG,Kim AJ,Raub CB,Frenkel V

更新日期：2020-06-22 00:00:00

abstract：:Diffuse optical imaging using non-ionizing radiation is a non-invasive method that shows promise towards breast cancer diagnosis. Hand-held optical imagers show potential for clinical translation of the technology, yet they have not been used towards 3D tomography. Herein, 3D tomography of human breast tissue in vivo ...

journal_title：Physics in medicine and biology

authors： Erickson SJ,Martinez SL,DeCerce J,Romero A,Caldera L,Godavarty A

更新日期：2013-03-07 00:00:00

abstract：:Calibration methods are investigated for the determination of bone density by the Compton scattering method. The scattered radiation from materials of different densities and dimensions is measured for this purpose. A function for the dependence of the intensity on these parameters is derived and compared with the exp...

journal_title：Physics in medicine and biology

authors： Leichter I,Weinreb A,Hazan G

更新日期：1980-07-01 00:00:00