Preliminary studies of the antifungal activities of some medicinal plants against Basidiobolus and some other pathogenic fungi.

Abstract:

:The antifungal activities of extracts of 10 medicinal plants collected from south-eastern parts of Nigeria were tested against seven pathogenic fungi using the broth dilution and agar plate methods. All the extracts at 1:10 dilution inhibited the growth of Basidiobolus haptosporus and B. ranarum but did not inhibit that of Aspergillus fumigatus, Geotrichum candidum and Candida albicans. While extracts from Piper guineense, Ocimum gratissimum, Moringa oleifera and Erythrophleum suaveolens inhibited the growth of Trichophyton rubrum and T. mentagrophytes, those from Fatropha curcas, Mitracarpus villosus, Azadirachta indica and Gongronema latifolium failed to do so at 1:10 dilution. Extract from Piper sp. was also able to inhibit the growth of B. haptosporus at a concentration as low as 1:80 dilution followed by those of Ocimum and Rauvolfia spp. at 1:40 dilution. These results indicate possible use of certain plant extracts in the treatment of subcutaneous phycomycosis in humans and animals.

journal_name

Mycoses

journal_title

Mycoses

authors

Nwosu MO,Okafor JI

doi

10.1111/j.1439-0507.1995.tb00048.x

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

191-5

issue

5-6

eissn

0933-7407

issn

1439-0507

journal_volume

38

pub_type

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