Abstract:
:Aspergillus flavus is the second most important Aspergillus species causing human infections in tropical countries. Despite an increasing number of infections of A. flavus in Iran, the molecular epidemiology of clinical and environmental strains has not been well studied. We used a panel of nine microsatellite markers to analyse the genetic relatedness of A. flavus. Microsatellite typing of 143 (n = 119 clinical and n = 24 environmental) isolates demonstrated 118 different genotypes. A possible outbreak at a pulmonary ward was discovered. The discriminatory power for the individual markers ranged from 0.4812 to 0.9457 and the panel of all nine markers combined yielded a diversity index of 0.9948. This high-resolution typing method assists in better understanding of the molecular epidemiology of A. flavus.
journal_name
Mycosesjournal_title
Mycosesauthors
Khodavaisy S,Badali H,Rezaie S,Nabili M,Moghadam KG,Afhami S,Hagen F,Aala F,Hashemi SJ,Meis JFdoi
10.1111/myc.12451subject
Has Abstractpub_date
2016-04-01 00:00:00pages
220-225issue
4eissn
0933-7407issn
1439-0507journal_volume
59pub_type
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