Survival after combined modality therapy for pancreatic cancer.

Abstract:

:Twenty consecutive patients with unresectable, locally advanced pancreatic cancer were treated with split courses of radiotherapy (RT) and simultaneous multidrug chemotherapy consisting of 5 fluorouracil, continuous infusion, streptozotocin, and cisplatin. A separate, retrospective study identified a group of 28 contemporary patients with less advanced pancreatic cancers, all of which were successfully resected. The survival rate of the two groups were similar over the first 2 years, although it initially favored the unresectable group. This pattern of survival among patients treated with combined modality therapy provides a basis for new studies. At the two clinical extremes, these include treatment of unresectable tumors previously considered ineligible for this treatment and initial treatment before resection of stage I tumors.

journal_name

J Clin Gastroenterol

authors

Bruckner HW,Kalnicki S,Dalton J,Snady H,Schwartz GK,Chesser MR,Lehrer D,Mandeli J,Harpaz N,Janus C

doi

10.1097/00004836-199304000-00006

subject

Has Abstract

pub_date

1993-04-01 00:00:00

pages

199-203

issue

3

eissn

0192-0790

issn

1539-2031

journal_volume

16

pub_type

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