Abstract：
OBJECTIVE:To evaluate the performance of serological tests using dried blood on filter-papers (micro-card agglutination test for trypanosomiasis (micro-CATT)) performed under field and laboratory conditions and using whole blood ((CATT/T.b. gambiense) (wb-CATT) and latex agglutination (LATEX/T.b. gambiense) (wb-LATEX)) for the serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa. METHODS:We evaluated the micro-CATT, wb-CATT and wb-LATEX methods in Côte d'Ivoire and the Central African Republic by screening 940 people. Sensitivity and specificity were calculated for each serological test; only patients with the confirmed presence of trypanosomes in the blood or lymph aspirate were considered true positives. Positive and negative predictive values were also calculated. FINDINGS:Each of the tests showed a lower sensitivity in the Central African Republic than in Côte d'Ivoire. CONCLUSION:The results confirmed the efficiency of the classic wb-CATT to detect sleeping sickness patients. The micro-CATT method can be used for human African trypanosomiasis surveillance if the test is performed on the same day as the blood collection, or if samples are stored at 4 degrees C. Otherwise, micro-CATT can be used when absolute sensitivity is not required. wb-LATEX should only be used for high-specificity screening.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Truc P,Lejon V,Magnus E,Jamonneau V,Nangouma A,Verloo D,Penchenier L,Büscher Psubject
Has Abstractpub_date
2002-01-01 00:00:00pages
882-6issue
11eissn
0042-9686issn
1564-0604pii
S0042-96862002001100008journal_volume
80pub_type
杂志文章abstract：:The prevalence of ringworm of the scalp in many countries, and the fact that many of the current measures to control it are inconvenient for mass use, lend particular interest to the account given in this paper of mass treatment of tinea capitis in an Arab village in Israel. A total of 446 cases were treated, on an am...
journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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更新日期：1973-01-01 00:00:00
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journal_title：Bulletin of the World Health Organization
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pub_type： 新闻
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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journal_title：Bulletin of the World Health Organization
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