Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria in Australian Defence Force personnel.

abstract：:Cross-sectional entomological surveys were carried out during the 2006 dry and rainy seasons in Lagdo, Cameroon to measure the impact of rice cultivation on malaria transmission and to monitor vector susceptibility to insecticides. Adult anopheline mosquitoes were captured on human volunteers and by pyrethrum spray co...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Antonio-Nkondjio C,Atangana J,Ndo C,Awono-Ambene P,Fondjo E,Fontenille D,Simard F

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Microbial diarrheal diseases are one of the leading causes of child morbidity and mortality in developing countries. This study aimed to identify the main causes of non-bacterial diarrhea in Afghanistan. METHODS:A total of 699 stools were collected from children aged under 5 years who presented with diarrhe...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Elyan D,Wasfy M,El Mohammady H,Hassan K,Monestersky J,Noormal B,Oyofo B

更新日期：2014-08-01 00:00:00

abstract：:Chloroquine can no longer be recommended as the first-line treatment for uncomplicated malaria in several parts of Africa because of the increasing prevalence of chloroquine resistance. However, chloroquine was a highly effective treatment for malaria not only because of its ability to kill parasites quickly but also ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bojang KA,Schneider G,Forck S,Obaro SK,Jaffar S,Pinder M,Rowley J,Greenwood BM

更新日期：1998-01-01 00:00:00

abstract：:Both northern and southern Sudan are deploying artemisinin-based combinations against uncomplicated Plasmodium falciparum malaria (artesunate+sulfadoxine-pyrimethamine [AS+SP] in the north, artesunate+amodiaquine [AS+AQ] in the south). In 2003, we tested the efficacy of 3 day AS+SP and AS+AQ regimens in vivo in the is...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Hamour S,Melaku Y,Keus K,Wambugu J,Atkin S,Montgomery J,Ford N,Hook C,Checchi F

更新日期：2005-07-01 00:00:00

abstract：:Artemisinin derivatives are becoming the first-line treatment for uncomplicated malaria in areas with widespread resistance to chloroquine. Although generally safe and well tolerated, it has been suggested from animal experiments, and more recently from one human study with artemether-lumefantrine, that these compound...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McCall MB,Beynon AJ,Mylanus EA,van der Ven AJ,Sauerwein RW

更新日期：2006-12-01 00:00:00

abstract：:Clinical characteristics of patients with falciparum malaria, as well as sensitivity of Plasmodium falciparum to chloroquine and mefloquine, were investigated in 2 distinct strata within the same geographical area of the Amazon Basin. One stratum was the population living along the road, the other that living along th...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kremsner PG,Zotter GM,Feldmeier H,Bienzle U,Jansen-Rosseck R,Graninger W,Rocha RM,Wernsdorfer WH

更新日期：1989-03-01 00:00:00

abstract：:Schistosomiasis among pregnant women has been inadequately investigated. In order to determine the importance of Schistosoma mansoni in this subgroup, we conducted a cross-sectional survey of 972 women in Tanzania and investigated the prevalence of Schistosoma mansoni, hookworm and malaria and their associations with ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ajanga A,Lwambo NJ,Blair L,Nyandindi U,Fenwick A,Brooker S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Schistosoma haematobium infection is a major public health problem in most of Africa and the Middle East and praziquantel remains the only drug used for schistosomiasis control, therefore emergence of drug resistance is unavoidable. The antimalarial artemisinin-naphthoquine phosphate combination (co-ArNp) wa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： El-Beshbishi SN,El Bardicy S,Tadros M,Ayoub M,Taman A

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Bacteria are sources of numerous molecules used in treatment of infectious diseases. We investigated effects of molecules produced by 26 Pseudomonas aeruginosa strains against infection of mammalian cell cultures with Trypanosoma cruzi, the aetiological agent of Chagas disease. METHODS:Vero cells were infec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sass G,Miller Conrad LC,Nguyen TH,Stevens DA

更新日期：2020-07-01 00:00:00

abstract：:The WHO's new End TB Strategy 2016-2035 has evolved from previous global strategies to respond to old and new challenges and take advantage of new opportunities. It frames the global fight against TB as a development, social justice and human rights issue, while re-emphasizing the public health and clinical fundaments...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lönnroth K,Raviglione M

更新日期：2016-03-01 00:00:00

abstract：:Central nervous system involvement due to toxoplasmosis in an immunocompetent host is very rare. We report a case of an immunocompetent patient who presented with suspected tuberculous meningoencephalitis but showed no clinical response to antitubercular therapy. Later, toxoplasmic meningoencephalitis was proved by po...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kaushik RM,Mahajan SK,Sharma A,Kaushik R,Kukreti R

更新日期：2005-11-01 00:00:00

abstract：:Between May and September 1982 an extensive epidemic of poliomyelitis occurred in Gazankulu in the north-eastern region of South Africa, with a total of 260 paralysed cases and 42 deaths. A three-part study was instituted, the first of which established the aetiological agent of the epidemic to be poliovirus type 1. T...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Johnson S,Schoub BD,McAnerney JM,Gear JS,Moodie JM,Garrity SL,Klaassen KI,Küstner HG

更新日期：1984-01-01 00:00:00

abstract：:We describe here a method, potentially suitable for field applications, for semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings, which are taken normally for smear microscopy. Thirty acid-fast bacilli-negative paucibacillary (PB) leprosy patients comprised the main study group; eight acid-fa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chaturvedi V,Girdhar BK,Sengupta U,Sinha S

更新日期：2007-07-01 00:00:00

abstract：Background:After new analysis, Sanofi Pasteur now recommends their dengue vaccine (Dengvaxia) should only be given to individuals previously infected with dengue and the World Health Organization's recommendations regarding its use are currently being revised. As a result, the potential costs of performing large-scale ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Turner HC,Wills BA,Rahman M,Quoc Cuong H,Thwaites GE,Boni MF,Clapham HE

更新日期：2018-08-01 00:00:00

abstract：:Streptococcal infection remains almost the sole cause of the clinical syndrome of acute glomerulonephritis in African children. Evidence for this is in elevated levels of antistreptolysin "O" (ASO) titre in 93% of 28 patients and growth of Group Abeta haemolytic streptococci from the skin and throat in 32%. Spread of ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Hallett AF,Adhikari M,Cooper R,Coovadia HM

更新日期：1977-01-01 00:00:00

abstract：:The frequency, intensity and clinical features of onchocerciasis in the two ethnic groups (Blacks and Chachilla--an indigenous tribe) in the endemic foci of the disease in Esmeraldas province (Ecuador) were evaluated. The incidence of infection and intensity of the disease seen in both groups were directly related to ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Molea J,Guderian RH,Proaño R,Carrillo R,Swanson WL

更新日期：1984-01-01 00:00:00

abstract：:Schistosomiasis is a major parasitic infection of tropical areas. We present a 26-year-old male immigrant from Egypt with acute abdomen due to schistosomial infection, mimicking symptoms of acute appendicitis, with histopathological detection and representation of schistosomial eggs in the unusual area of the greater ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Konstantinidou E,Alexiou C,Demonakou M,Sakellaridis T,Fotopoulos A,Antsaklis G

更新日期：2009-10-01 00:00:00

abstract：:Ciprofloxacin (20 mg/kg/d) or ofloxacin (12 mg/kg/d) given for a median of 15 weeks (range 12-40) were used for maintenance treatment of 57 adult patients with melioidosis. The median duration of follow-up in the 45 patients who complied with treatment and were followed for at least 6 months was 28 months (range 6-65)...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chaowagul W,Suputtamongkul Y,Smith MD,White NJ

更新日期：1997-09-01 00:00:00

abstract：:In 2005-2006, a large outbreak of Chikungunya (CHIK) fever occurred on the western Indian Ocean Islands. In Mayotte, concurrent with an enhanced passive case notification system, we carried out two surveys. A seroprevalence survey designed to document recent CHIK infection was conducted on serum samples collected from...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sissoko D,Malvy D,Giry C,Delmas G,Paquet C,Gabrie P,Pettinelli F,Sanquer MA,Pierre V

更新日期：2008-08-01 00:00:00

abstract：:Considerable evidence documents the importance of co-factors, including the immune response, in expression of oncogenicity of tumour viruses. To determine whether a common protozoal infection that can depress lymphocyte function alters manifestations of oncogenic virus infection, a mouse model of Toxoplasma infection ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McLeod R,Estes RG,Cohen H

更新日期：1985-01-01 00:00:00

abstract：:Cold, acidified anthrone was used to test 200 wild-caught sandflies (Phlebotomus ariasi females) for the presence of fructose. This sugar, or others with a fructose moiety, were demonstrable in 157 (79%) of the flies; proportions of flies positive in different tests ranged from 44 to 91%. Higher proportions of flies g...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Young CJ,Turner DP,Killick-Kendrick R,Rioux JA,Leaney AJ

更新日期：1980-01-01 00:00:00

abstract：:Epidemiological data gathered by the Onchocerciasis Control Programme from 66 villages in West Africa have been analysed. All of these villages were surveyed twice and 10 a third time. The first surveys were conducted around the time when control activities started and provide baseline data against which to assess the...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kirkwood B,Smith P,Marshall T,Prost A

更新日期：1983-01-01 00:00:00

abstract：:The spread of chloroquine resistance throughout the world poses a major problem in combating malaria. In the present study, an efficient polymerase chain reaction-single strand conformational polymorphism (PCR--SSCP)-based assay detected the PfCRT K76T point mutation, which is a marker for chloroquine resistance. For ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mishra S,Raj DK,Hazra RK,Dash AP,Supakar PC

更新日期：2006-03-01 00:00:00

abstract：:We report the results of a short study of the epidemiology of Leishmania tropica in the Sheikh Maksoud District of Aleppo, Syria. The present and past status of infection in a community of about 100,000 people are assessed from prevalence and incidence data obtained by active and passive case detection, and from a ski...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ashford RW,Rioux JA,Jalouk L,Khiami A,Dye C

更新日期：1993-05-01 00:00:00

abstract：:In order to estimate the importance as a public health problem of skin diseases, we investigated the prevalence and severity of skin diseases in a representative sample of children in Mali. 1817 children were randomly selected in 30 clusters by probability-proportional-to-size sampling in Koulikoro region. The mean pr...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mahé A,Prual A,Konaté M,Bobin P

更新日期：1995-09-01 00:00:00

abstract：:Countries around the world are facing an enormous challenge due to the COVID-19 pandemic. The pressure that the pandemic inflicts on health systems could certainly impact on the care, control, and elimination of neglected tropical diseases (NTDs). From mid-January 2020, Ethiopia started to prepare for the prevention a...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Abdela SG,van Griensven J,Seife F,Enbiale W

更新日期：2020-10-05 00:00:00

abstract：:A recently described simple kit for isolating African trypanosomes in vitro (KIVI) was tested further with blood samples from man and other animals in Côte d'Ivoire and République du Congo. A high rate of success was achieved, with positive cultures being found 5-36 d after inoculation. The method was also of value in...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Truc P,Aerts D,McNamara JJ,Claes Y,Allingham R,Le Ray D,Godfrey DG

更新日期：1992-11-01 00:00:00

abstract：:Data on malaria transmission intensity and prevalences of asexual parasites and of gametocytes were obtained in an urban district of Yaoundé, Cameroon. The transmission level from mosquito to human was determined by indoor night capture of mosquitoes on human volunteers, revealing a calculated entomological inoculatio...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： van der Kolk M,Tebo AE,Nimpaye H,Ndombol DN,Sauerwein RW,Eling WM

更新日期：2003-07-01 00:00:00

abstract：:Allopurinol and allopurinol ribonucleoside tested in vitro and in vivo for activity against Leishmania donovani. Activity in vitro was low against the amastigote form of this parasite with ED50 values of the order of 54 and 96 microM and 86 and 213 microM respectively for the two compounds. In vivo inhibition of up to...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Neal RA,Croft SL,Nelson DJ

更新日期：1985-01-01 00:00:00

abstract：:The involvement of the lung in 13 cases of human visceral leishmaniasis was studied. Interstitial pneumonitis with mononuclear cells was found in 76.8% of the cases; 53.8% also had foci of septal fibrosis. Leishmania were seen within macrophages in 3 cases only. However, all 10 interstitial pneumonitis cases showed PA...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Duarte MI,da Matta VL,Corbett CE,Laurenti MD,Chebabo R,Goto H

更新日期：1989-01-01 00:00:00