Abstract:
:In this era of changing priorities, regulations, and resources, it is useful to look both back and forward at the building of a division of child neurology in the context of the emergence of child neurology as a nationally and internationally recognized distinct subspecialty of both pediatrics and neurology. Both Pittsburgh and national colleagues of Dr Michael J. Painter were fortunate to have such a glimpse at a Festschrift held in his honor in January 2002 and, more recently, at the October 2002 meeting of Professors of Child Neurology, where he presented his view of "Building a Child Neurology Division the Old-Fashioned Way." The narrative that follows draws heavily from both of these events and from insights gained from Dr Painter's long and broad experience in the establishment and nurturing of both the specialty of child neurology and many of its current practitioners.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Schor NF,Crumrine PKdoi
10.1177/08830738030180020401subject
Has Abstractpub_date
2003-02-01 00:00:00pages
127-30issue
2eissn
0883-0738issn
1708-8283journal_volume
18pub_type
传,历史文章abstract::The relationship between somatic growth and neurocognitive outcome was studied in a cohort of 136 children with intrauterine growth retardation. The children were followed up from birth to 9 to 10 years of age by annual measurements of growth parameters, neurodevelopmental evaluations, and IQ. The rate of catch-up for...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808331082
更新日期:2009-07-01 00:00:00
abstract::Many neurodegenerative diseases can be misdiagnosed as cerebral palsy. The correct diagnosis is reached when the condition recurs in families or when there are specific clinical signs. The clinical and imaging features of 3 children, from 2 unrelated families, presenting with global developmental delay and dystonia ar...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813512026
更新日期:2014-11-01 00:00:00
abstract::The purpose of this study was to determine the etiologic factors, clinical characteristics, seasonal distributions, family history, response to corticosteroid therapy, recurrence and residual paralysis rates, and factors affecting these in pediatric facial palsy. Patients aged <18 years diagnosed with acute peripheral...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073819865682
更新日期:2019-12-01 00:00:00
abstract::Reversible posterior leukoencephalopathy syndrome is an increasingly recognized disorder with typical radiologic findings of bilateral gray- and white-matter abnormalities in the posterior regions of the cerebral hemispheres. The majority of patients with reversible posterior leukoencephalopathy syndrome are adults, a...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738060210060901
更新日期:2006-06-01 00:00:00
abstract::We report a case of a neonate with sectional narrowing of the spinal cord on the level of T12 to L2 and a deformed vertebral body on a different level, L4. In previously described cases of sectional spinal dysgenesis, the vertebral and spinal cord malformations are usually found on the same level. Our case may represe...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101600819
更新日期:2001-08-01 00:00:00
abstract::Corpus callosum agenesis, retardation, adducted thumbs, spastic paraparesis, and hydrocephalus (CRASH syndrome) is an X-linked recessive disorder caused by mutations in the neuronal cell adhesion molecule L1 (LICAM) gene. L1 plays a key role in axon outgrowth and pathfinding during the development of the nervous syste...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380001500407
更新日期:2000-04-01 00:00:00
abstract::We report the case of a 15-month-old critically ill child with stimulus-induced diffuse voltage attenuation, a previously unreported electroencephalogram pattern. No clinical evidence of seizure activity was associated with these EEG changes. The patient went on to have a full recovery. This case suggests that critica...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808324532
更新日期:2009-04-01 00:00:00
abstract::Attention-deficit hyperactivity disorder (ADHD) is described as the most common neurobehavioral condition of childhood. We raise the concern that ADHD is not a disease per se but rather a group of symptoms representing a final common behavioral pathway for a gamut of emotional, psychological, and/or learning problems....
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/08830738050200121301
更新日期:2005-12-01 00:00:00
abstract::Two boys, aged 7 and 12 years, with nondominant (right) hemispheric acquired vascular lesions and left visual-field disturbances had right spatial constructional disabilities, contralateral to that which would be expected. These unusual disturbances may represent the previously unreported phenomena of ipsilateral negl...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389400900109
更新日期:1994-01-01 00:00:00
abstract::Intracranial tumors are the most common solid tumors in children. The infratentorial compartment will be the primary site for 60% to 70% of these tumors, including astrocytomas, medulloblastomas, and ependymomas. Several technological advancements have increased our knowledge of the cell biology of pediatric brain tum...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073808321768
更新日期:2008-10-01 00:00:00
abstract::Behçet disease is a systemic vasculitis of unknown etiology that can affect the neurologic system. Neuro-Behçet disease is not well defined in children and adolescents, and the diagnosis is difficult to make in this population as they often present with insufficient symptoms to meet diagnostic criteria. Psychiatric sy...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813504137
更新日期:2014-09-01 00:00:00
abstract::Six cases of childhood multiple sclerosis (MS) are presented. All patients (three boys and three girls) were black and came from the Washington, DC, metropolitan area. Age at onset of the disease ranged from 8 to 17 years. Although motor deficits, optic neuritis, and ataxia were similar to those previously reported in...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389100600112
更新日期:1991-01-01 00:00:00
abstract::This cross-sectional study was planned to study the blood ammonia levels in epileptic children on 2 dose ranges of valproic acid monotherapy. A total of 60 epileptic children aged 3 months to 12 years, that were on valproic acid monotherapy for at least 3 months, were enrolled and divided into 2 groups, a low-dose gro...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073810377235
更新日期:2011-01-01 00:00:00
abstract::A 15-month-old girl demonstrated progressive weakness in all limbs. Magnetic resonance imaging (MRI) on admission revealed (1) diffuse and symmetric cervical cord swelling, (2) diffuse decrease and increase in signal intensity within the affected cord on T1- and T2-weighted images, respectively, (3) preserved anatomic...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389200700214
更新日期:1992-04-01 00:00:00
abstract::High-dose phenobarbital therapy is an effective treatment for refractory status epilepticus in children. The advantages of this therapy include milder adverse effects without limits for maximal phenobarbital levels or doses during the initial phase of treatment. However, little is known about the safety of continuing ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808331360
更新日期:2009-12-01 00:00:00
abstract::Adolescence is an important period, marked by significant changes in biological and psychosocial domains. Epilepsy is a chronic neurologic disorder associated with social stigma and prejudice. The etiology of depression in epilepsy appears to be a complex interplay between psychosocial and neurobiologic factors. This ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820954060
更新日期:2021-02-01 00:00:00
abstract::Executive dysfunction occurs in sickle cell anemia, but there are few early data. Infants with sickle cell anemia (n = 14) and controls (n = 14) performed the "A-not-B" and Object Retrieval search tasks, measuring precursors of executive function at 9 and 12 months. Significant group differences were not found. Howeve...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812453495
更新日期:2013-10-01 00:00:00
abstract::Three normal children with headache occurring only with exertion were advised to try "head cooling" (eg, immersion of the head in cold water, cold water poured over the head, application of a cold, wet towel or ice pack) at the onset of headache. The patients were followed up quarterly as outpatients, and the effectiv...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/7010.2006.00227
更新日期:2006-12-01 00:00:00
abstract::Tuberous sclerosis complex is a multisystem, chronic genetic condition characterized by systemic growth of benign tumors and often accompanied by epilepsy, autism spectrum disorders, and intellectual disability. Nonetheless, the neurodevelopmental phenotype of these patients is not often detailed. The authors describe...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073815600871
更新日期:2015-12-01 00:00:00
abstract::We studied eight patients with rigid spine syndrome aged 8 to 20 years at the time of first examination. Muscle weakness, rigid spine, and flexion contracture of elbows and ankles were noted in the first 6 years of age. Radiological study of the cervical spine revealed considerable reduction not only of flexion, but a...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388900400405
更新日期:1989-10-01 00:00:00
abstract::The objective of this study was to compare the efficacy of corticotropin (ACTH) versus vigabatrin in treating infantile spasms and to determine which medication has a more favorable long-term outcome in terms of cognitive function, evolution of epilepsy, and incidence of autism. Patients with infantile spasms were inc...
journal_title:Journal of child neurology
pub_type: 临床试验,杂志文章
doi:10.1177/08830738030180030801
更新日期:2003-03-01 00:00:00
abstract::Paramyotonia congenita in 22 members of Arab (Omani) family is reported. Four generations were affected. All had early onset around 1 year of age, with myotonia and cold intolerance. Age of onset in the index case was at 3 months of age. Six members with the disease were examined and investigated. To our knowledge, th...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808330185
更新日期:2010-02-01 00:00:00
abstract::We investigated familial and environmental risk factors in a cohort of South African children diagnosed with attention-deficit hyperactivity disorder (ADHD). A prospective, hospital-based case control study was conducted comprising 50 children diagnosed with ADHD and 50 matched non-ADHD controls. The adjusted effect o...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814560630
更新日期:2015-09-01 00:00:00
abstract::Klonopin (clonazepam; Genentech Inc, South San Francisco, California) oral wafers are benzodiazepines with anticonvulsive and anxiolytic properties. Our institution has been prescribing clonazepam wafers for acute treatment of prolonged seizures for years. Patients' size determined dosing at 0.25, 0.5, 1, or 2 mg wafe...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073810368312
更新日期:2010-12-01 00:00:00
abstract::Neuromyelitis optica is a rare, severe idiopathic disease that predominantly involves optic nerves and spinal cord. Main clinical features of neuromyelitis optica are visual loss, paraparesis or tetraparesis, sensory loss, and sphincter dysfunction. A 13-year-old girl with vision loss and behavioral change was admitte...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812448837
更新日期:2013-05-01 00:00:00
abstract::The purpose of this study was to determine whether children with epilepsy undergoing valproate therapy and who are otherwise healthy have lower levels of serum and muscle carnitine. A total of 50 patients with epilepsy, 3 to 14 years of age, who were treated solely with valproate and free of abnormal neurologic findin...
journal_title:Journal of child neurology
pub_type: 临床试验,杂志文章
doi:10.1177/0883073808321060
更新日期:2009-01-01 00:00:00
abstract::Intractable epilepsies pose a therapeutic challenge. Precise localization of the epileptic focus is imperative before planning surgical intervention. Functional imaging is an important component of presurgical work-up. Positron emission tomography is unavailable in developing countries; hence, the need to evaluate the...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101600405
更新日期:2001-04-01 00:00:00
abstract::Cavernous haemangiomas, or cavernous malformations, have been reported during pregnancy, most of which have been either supratentorial or spinal lesions. We encountered a 15-year old pregnant patient with a rapidly progressive and haemorrhagic brainstem cavernous haemangioma. The case presented here describes the hist...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812457459
更新日期:2013-10-01 00:00:00
abstract::Ataxia with oculomotor apraxia type 1 (AOA1) is an autosomal recessive disease characterized by early-onset and slowly progressive cerebellar ataxia, areflexia, and peripheral neuropathy. Ocular apraxia is most prominent in the early stage of the disease, by contrast, hypoalbuminemia, hypercholesterolemia, and cogniti...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808314959
更新日期:2008-08-01 00:00:00
abstract::Abnormal zinc metabolism in a 6-year-old male patient with Landau-Kleffner syndrome (acquired aphasia and convulsive disorder) is the subject of our report. We describe a significant decrease of erythrocyte and plasma zinc levels in the patient as compared with normal. Red blood cell zinc content is normally 38.5 +/- ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388700200105
更新日期:1987-01-01 00:00:00