Abstract:
:We investigated familial and environmental risk factors in a cohort of South African children diagnosed with attention-deficit hyperactivity disorder (ADHD). A prospective, hospital-based case control study was conducted comprising 50 children diagnosed with ADHD and 50 matched non-ADHD controls. The adjusted effect of familial-environmental risk factors on ADHD was determined by systematic assessment. Birth complications, parental psychiatric disorder, maternal ADHD, early childhood trauma, and nonmaternal child care were significant risk factors for ADHD. Prolonged breastfeeding was found to be protective. In a multivariable logistic regression model, 5 criteria (birth complications, breastfeeding <3 months, at least 1 parent with tertiary education, presence of parental psychiatric disorder, and nonmaternal primary caregiver) differentiated ADHD from non-ADHD controls with a sensitivity and specificity of 74% and 86%, respectively. We found a correlation between certain familial and environmental risk factors and ADHD. A 5-criterion multivariable logistic regression model may offer clinical guidance in ADHD diagnosis.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
van Dyk L,Springer P,Kidd M,Steyn N,Solomons R,van Toorn Rdoi
10.1177/0883073814560630subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1327-32issue
10eissn
0883-0738issn
1708-8283pii
0883073814560630journal_volume
30pub_type
杂志文章abstract::The objective of this study was to investigate the incidence of acute flaccid paralysis in the pediatric population of Honduras over an 11-year period, determine what percentage of acute flaccid paralysis was Guillain-Barré syndrome, and identify the epidemiologic features of Guillain-Barré syndrome. There were 546 ch...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738030180110801
更新日期:2003-11-01 00:00:00
abstract::There is increased necessity to focus research on school-aged athletes with sports-related concussion (SRC). This study assessed differences in symptom reporting and neurocognitive performance in youth athletes who sustained a sports-related concussion. A total of 1345 concussed and 3529 nonconcussed athletes (ages 8-...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073818766815
更新日期:2018-06-01 00:00:00
abstract::In this study we investigated centrally mediated parasympathetic regulation of modulated cardiac vagal tone among children with severe cyanotic and pallid breath-holding spells by examining respiratory sinus arrhythmia. Respiratory sinus arrhythmia was evaluated in 41 children; 17 subjects with cyanotic breath-holding...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389801300905
更新日期:1998-09-01 00:00:00
abstract::Neurofibromatosis type 1 is associated with executive dysfunctions and comorbidity with attention-deficit hyperactivity disorder (ADHD) in 30% to 50% of children. This study was designed to clarify the neurocognitive phenotype observed in neurofibromatosis type 1 by testing the hypothesis that children with neurofibro...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813517001
更新日期:2014-10-01 00:00:00
abstract::Executive dysfunction occurs in sickle cell anemia, but there are few early data. Infants with sickle cell anemia (n = 14) and controls (n = 14) performed the "A-not-B" and Object Retrieval search tasks, measuring precursors of executive function at 9 and 12 months. Significant group differences were not found. Howeve...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812453495
更新日期:2013-10-01 00:00:00
abstract::Sjögren-Larsson syndrome is an inherited disorder of lipid metabolism caused by mutations in the ALDH3A2 gene that codes for fatty aldehyde dehydrogenase, which results in accumulation of fatty aldehydes and alcohols and is characterized by ichthyosis, intellectual disability, and spastic diplegia/quadriplegia. The au...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812460581
更新日期:2013-10-01 00:00:00
abstract::Managing severe epilepsy syndromes of early childhood is challenging as the seizures are typically resistant to treatment and may cause disabling mental and behavioral problems in later life. A comprehensive treatment plan includes pharmacologic, nonpharmacologic, and surgical options. This article reviews clinical st...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073809338153
更新日期:2009-08-01 00:00:00
abstract::Seven school-aged children treated for temporal lobe astrocytomas with surgical resection and irradiation were prospectively tested to evaluate their intellectual, academic, personality, and neurologic status after therapy. At their most recent follow-up examination, neuropsychologic functioning was adequate in only t...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388800300111
更新日期:1988-01-01 00:00:00
abstract::The ketogenic diet has traditionally been considered an anticonvulsant therapy of last resort, despite excellent efficacy and limited side effects. We hypothesized that the ketogenic diet would have similar results in patients with new-onset epilepsy. A retrospective study was conducted of patients started on the keto...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738050200010501
更新日期:2005-01-01 00:00:00
abstract::Acute cerebellitis is a rare condition often considered within the group of acute postinfectious cerebellar ataxia despite its distinctive clinical and imaging features. We retrieved clinical, laboratory, and follow-up data of 15 children diagnosed with acute cerebellitis in our department between 2011 and 2019. There...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820901407
更新日期:2020-05-01 00:00:00
abstract::We report a divergent ependymal tumor of the posterior fossa (ependymoblastoma/anaplastic ependymoma) observed in an 8-year-old boy. The tumor showed the histological pattern typical of an ependymoblastoma (tubular-papillary fetaloid architecture with stratification of the tumor cells) next to areas in which findings ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808314160
更新日期:2008-09-01 00:00:00
abstract::Two siblings with familial encephalopathy, calcification of the basal ganglia, and cerebrospinal fluid lymphocytosis, constituting the triad of Aicardi-Goutieres syndrome, are reported. This syndrome resembles congenital intrauterine infections, which must be meticulously excluded. Aicardi-Goutieres syndrome is extrem...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101601009
更新日期:2001-10-01 00:00:00
abstract::Ataxia with oculomotor apraxia type 1 (AOA1) is an autosomal recessive disease characterized by early-onset and slowly progressive cerebellar ataxia, areflexia, and peripheral neuropathy. Ocular apraxia is most prominent in the early stage of the disease, by contrast, hypoalbuminemia, hypercholesterolemia, and cogniti...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808314959
更新日期:2008-08-01 00:00:00
abstract::This article reports the results of a study on the relationship between cord blood levels of erythropoietin and periventricular leukomalacia. Cord blood was obtained from 19 infants with gestational age between 27 and 32 weeks. Cystic periventricular leukomalacia was seen in 4 of them. Erythropoietin levels were not d...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073807308697
更新日期:2008-02-01 00:00:00
abstract::We evaluated the neuropsychological and neurologic outcome of 15 long-term survivors of posterior fossa tumors who were treated between 1970 and 1984 with cranial irradiation (n = 15) and surgery (n = 14). The interval between diagnosis and evaluation ranged from 4 to 20 years (median = 10 years). Earlier age at diagn...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389501000308
更新日期:1995-05-01 00:00:00
abstract::The purpose of this survey and record review was to characterize emergency department management of unprovoked seizures and status epilepticus in children in Illinois. The survey was sent to 119 participating emergency departments in the Emergency Medical Services for Children program; responses were received from 103...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814566626
更新日期:2015-10-01 00:00:00
abstract::This study was performed to determine the utility of 99mTc-hexamethylpropylenamine oxime (HMPAO) brain single photon emission computed tomography (SPECT) in evaluating patients with childhood absence epilepsy. Twenty-three patients (13 female, 10 male), aged 7 to 15 years (mean age 10.3 +/- 2.2), were studied. All pat...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738030180080401
更新日期:2003-08-01 00:00:00
abstract::Many neurodegenerative diseases can be misdiagnosed as cerebral palsy. The correct diagnosis is reached when the condition recurs in families or when there are specific clinical signs. The clinical and imaging features of 3 children, from 2 unrelated families, presenting with global developmental delay and dystonia ar...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813512026
更新日期:2014-11-01 00:00:00
abstract::Sensory rhizotomy in the treatment of spasticity has been evolving over the past century since its first use in 1888. This paper reviews its historical evolution, current physiologic basis, range in current surgical technique, and the outcome, along with complications seen over the past decade since its repopularizati...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073896011001S06
更新日期:1996-11-01 00:00:00
abstract::The objective of this article is to review primary and secondary causes of carnitine deficiency, emphasizing recent advances in our knowledge of fatty acid oxidation. It is now understood that the cellular metabolism of fatty acids requires the cytosolic carnitine cycle and the mitochondrial beta-oxidation cycle. Carn...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract::The size and reactivity to light of the pupil in infants with intraventricular hemorrhage has been variously described in the literature. These descriptions have included miosis, reactivity to light, nonreactivity to light, and anisocoria. We studied the size and light reactivity of 20 infants with intraventricular he...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389400900423
更新日期:1994-10-01 00:00:00
abstract::The authors conducted a systematic literature review of preventive pharmacological treatments for episodic childhood migraines searching several databases through May 20, 2012. Episodic migraine prevention was examined in 24 publications of randomized controlled trials that enrolled 1578 children in 16 nonrandomized s...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073813488659
更新日期:2013-10-01 00:00:00
abstract::Lissencephaly is a brain malformation manifested by a smooth cerebral surface and caused by incomplete neuronal migration. Clinical sequellae include minor craniofacial changes (bitemporal hollowing, small jaw), severe mental retardation, and other neurological abnormalities. Patients with classical or type I lissence...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389000500113
更新日期:1990-01-01 00:00:00
abstract::We report a case of a neonate with sectional narrowing of the spinal cord on the level of T12 to L2 and a deformed vertebral body on a different level, L4. In previously described cases of sectional spinal dysgenesis, the vertebral and spinal cord malformations are usually found on the same level. Our case may represe...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101600819
更新日期:2001-08-01 00:00:00
abstract::Levetiracetam, one of the newer-generation antiepilepsy drugs, is not currently approved for use in children. Given its favorable efficacy, pharmacokinetic, and, particularly, safety profile in adults, we felt that it may be a useful antiepilepsy drug for children with refractory epilepsy. We treated 39 patients (mean...
journal_title:Journal of child neurology
pub_type: 临床试验,杂志文章
doi:10.1177/088307380201700603
更新日期:2002-06-01 00:00:00
abstract::Vigabatrin has been studied in adult drug-resistant epilepsy since 1982 in single-blind and double-blind studies followed by long-term, open evaluations. These studies have provided evidence that vigabatrin is a potent and well-tolerated antiepileptic drug and support its potential value in pediatric epilepsy. The lac...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::We report two children with transient myasthenia gravis preceded by viral illnesses. The first is a 5-year-old boy who developed oculobulbar weakness 2 weeks following a varicella-zoster infection. The second is a 4-year-old boy who developed facial diplegia and dysarthria several weeks following a viral pharyngitis. ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738050200051501
更新日期:2005-05-01 00:00:00
abstract::The authors provide an update on most issues related to biology, diagnosis, and treatment of children with ependymoma based on a literature review. Ependymoma is the third most common brain tumor in children and overall survival ranges from 24% to 75% at 5 years. The extent of surgical resection remains the principal ...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073809339212
更新日期:2009-11-01 00:00:00
abstract::Adolescence is an important period, marked by significant changes in biological and psychosocial domains. Epilepsy is a chronic neurologic disorder associated with social stigma and prejudice. The etiology of depression in epilepsy appears to be a complex interplay between psychosocial and neurobiologic factors. This ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820954060
更新日期:2021-02-01 00:00:00
abstract::Pediatric brain tumors are the leading cause of cancer-related death during childhood. Since the first pediatric brain tumor clinical trials, the field has seen improved outcomes in some, but not all tumor types. In the past few decades, a number of promising new therapeutic agents have emerged, yet only a few of thes...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073815604221
更新日期:2016-10-01 00:00:00