Neurobehavioral and neurologic outcome in long-term survivors of posterior fossa brain tumors: role of age and perioperative factors.


:We evaluated the neuropsychological and neurologic outcome of 15 long-term survivors of posterior fossa tumors who were treated between 1970 and 1984 with cranial irradiation (n = 15) and surgery (n = 14). The interval between diagnosis and evaluation ranged from 4 to 20 years (median = 10 years). Earlier age at diagnosis (< 6 years) was associated with an increased incidence of severe neurologic and neuropsychological sequelae. Hydrocephalus, obtundation, and tumor extension outside the vermis also were more prevalent in the younger group. Poor neurobehavioral outcomes in young children with posterior fossa tumors may be related to more aggressive tumor growth or complications of the initial therapy and not solely due to toxicity from craniospinal irradiation.


J Child Neurol


Chapman CA,Waber DP,Bernstein JH,Pomeroy SL,LaVally B,Sallan SE,Tarbell N




Has Abstract


1995-05-01 00:00:00












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    journal_title:Journal of child neurology

    pub_type: 杂志文章


    authors: Steen RG,Hu XJ,Elliott VE,Miles MA,Jones S,Wang WC

    更新日期:2002-02-01 00:00:00

  • Pediatric acute transverse myelitis overview and differential diagnosis.

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    journal_title:Journal of child neurology

    pub_type: 杂志文章,评审


    authors: Wolf VL,Lupo PJ,Lotze TE

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  • Auditory brainstem evoked potentials in early-treated congenital hypothyroidism.

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    journal_title:Journal of child neurology

    pub_type: 杂志文章


    authors: Chou YH,Wang PJ

    更新日期:2002-07-01 00:00:00

  • Neurodevelopmental outcomes in very low-birth-weight infants in Korea: 1998-2007 vs 1989-1997.

    abstract::The authors reviewed the medical records of very low-birth-weight infants admitted from 1998 to 2007 and compared neurodevelopmental outcomes with their previously reported data from 1989 to 1997. The recent group included 824 infants, and the previous group included 471 infants. Neurodevelopmental outcomes were class...

    journal_title:Journal of child neurology

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    更新日期:2011-11-01 00:00:00

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    journal_title:Journal of child neurology

    pub_type: 杂志文章


    authors: El-Bitar MK,Muwakkit SA,Abboud MR,Sawaya RA,Boustany RM

    更新日期:2010-08-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2010-12-01 00:00:00

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    journal_title:Journal of child neurology

    pub_type: 杂志文章


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    更新日期:2011-03-01 00:00:00

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    journal_title:Journal of child neurology

    pub_type: 杂志文章,评审


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    更新日期:2007-08-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 传,历史文章


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    更新日期:2003-03-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2001-07-01 00:00:00

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    journal_title:Journal of child neurology

    pub_type: 杂志文章


    authors: Tan H,Gürbüz T,Dağsuyu IM

    更新日期:2004-12-01 00:00:00

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    更新日期:2002-05-01 00:00:00

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    pub_type: 杂志文章


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    journal_title:Journal of child neurology

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    pub_type: 杂志文章


    authors: Gingold MK,Bodensteiner JB,Schochet SS,Jaynes M

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    journal_title:Journal of child neurology

    pub_type: 杂志文章


    authors: Chakrabarty B,Tripathi M,Gulati S,Yoganathan S,Pandit AK,Sinha A,Rathi BS

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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    更新日期:2013-11-01 00:00:00