Abstract:
:Children with neurodevelopmental disorders are at increased risk for sleep issues, which affect quality of life, cognitive function, and behavior. To determine the prevalence of sleep problems in children with the common neurodevelopmental disorder neurofibromatosis type 1, a cross-sectional study was performed on 129 affected subjects and 89 unaffected siblings, age 2 to 17 years, using the Sleep Disturbance Scale for Children questionnaire. Children with neurofibromatosis type 1 were significantly more likely to have disturbances in initiating and maintaining sleep, arousal, sleep-wake transition, and hyperhidrosis, but not problems with abnormal sleep breathing, or excessive somnolence. Although the overall sleep scores were higher in children with neurofibromatosis type 1, this was not related to a coexisting attention deficit disorder, cognitive impairment, or stimulant medication use. Collectively, these results demonstrate that children with neurofibromatosis type 1 are more likely to have sleep disturbances, and support the use of appropriate interventions for this at-risk population.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Licis AK,Vallorani A,Gao F,Chen C,Lenox J,Yamada KA,Duntley SP,Gutmann DHdoi
10.1177/0883073813500849subject
Has Abstractpub_date
2013-11-01 00:00:00pages
1400-1405issue
11eissn
0883-0738issn
1708-8283pii
0883073813500849journal_volume
28pub_type
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