Abstract:
:Abnormal zinc metabolism in a 6-year-old male patient with Landau-Kleffner syndrome (acquired aphasia and convulsive disorder) is the subject of our report. We describe a significant decrease of erythrocyte and plasma zinc levels in the patient as compared with normal. Red blood cell zinc content is normally 38.5 +/- 2.7 micrograms/g hemoglobin v 16.5 micrograms/g hemoglobin found in the patient. Plasma zinc level is 94.6 +/- 10.4 micrograms/dL in normal in comparison with 50.4 micrograms/dL in the patient. Normal oral zinc tolerance test performed on the patient precludes altered zinc absorption or increased urinary loss. The possible connection between abnormal zinc metabolism and the pathophysiology of Landau-Kleffner syndrome is discussed.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Lerman-Sagie T,Statter M,Lerman Pdoi
10.1177/088307388700200105subject
Has Abstractpub_date
1987-01-01 00:00:00pages
28-30issue
1eissn
0883-0738issn
1708-8283journal_volume
2pub_type
杂志文章abstract::We reviewed the data from 215 consecutively imaged children who were referred because of neurologic disease. We specifically looked for evidence of cerebral arterial infarction in the form of focal brain damage in an arterial vascular distribution. Twenty-eight showed an arterial infarction pattern. All the major cere...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388700200413
更新日期:1987-10-01 00:00:00
abstract::Amyotrophic lateral sclerosis is a fatal neurodegenerative disease. Epidemiologic data suggest that malnutrition is a common feature in amyotrophic lateral sclerosis and being overweight or obese confers a survival advantage in this patient population. In amyotrophic lateral sclerosis mouse models, a high-fat diet has...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813488669
更新日期:2013-08-01 00:00:00
abstract::The Baby Doe rules, a set of federal regulations on the treatment of extremely ill infants, went into effect in 1985. Some scholars have argued that these rules are inappropriate given that they fail to pay attention to the patient's suffering. Instead, researchers suggest that, when dealing with a severely impaired i...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073807304011
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:We present the diagnostic and clinical course of the first multicenter case series of pediatric patients with autoimmune encephalitis associated with N-type voltage-gated calcium channel antibodies. METHODS:Data from 2 university hospitals were retrospectively reviewed and records of 3 patients with autoimmu...
journal_title:Journal of child neurology
pub_type: 杂志文章,多中心研究
doi:10.1177/0883073819840448
更新日期:2019-08-01 00:00:00
abstract::This study presents a large multicenter cohort of children with cerebral venous thrombosis from 5 centers in the United States and analyzes their clinical findings and risk factors. Seventy patients were included in the study (25 neonates, 35%). The age ranged from 6 days to 12 years. Thirty-eight (55%) were younger t...
journal_title:Journal of child neurology
pub_type: 杂志文章,多中心研究
doi:10.1177/0883073807307976
更新日期:2008-01-01 00:00:00
abstract::Neural tube defects are common birth defects, the frequency of which appears to be reduced by maternal supplementation and/or fortification of folic acid. Latin Americans have a high incidence of neural tube defects. We surveyed the dietary intake of Honduran women of childbearing age using a 24-hour dietary recall qu...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380201700506
更新日期:2002-05-01 00:00:00
abstract::The aim of this study was to clarify the relationship between neurologic findings and outcome of patients with West syndrome, focusing on the popliteal angle. The complete neurologic examination, including an assessment of the popliteal angle and muscle tone, was performed on 45 patients with West syndrome. A tight po...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738060210101801
更新日期:2006-10-01 00:00:00
abstract::The objective of this study is to determine the long-term outcome of children with intractable epilepsy who have diffuse cortical hypometabolism on 2-deoxy-2-((18)F)fluoro-D-glucose positron emission tomography (FDG-PET) scans. Seventeen children with intractable epilepsy showing bilateral, diffuse cortical hypometabo...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073811416363
更新日期:2012-01-01 00:00:00
abstract::Two children are described who suddenly developed an encephalitic illness with intractable bilateral facial seizures. The seizures subsided over several days, but the children were left with the signs of pseudobulbar palsy and are unable to speak or swallow effectively. Bilateral destructive lesions in the opercular r...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388900400213
更新日期:1989-04-01 00:00:00
abstract::An association between overweight and attention-deficit/hyperactivity disorder (ADHD) in children was previously suggested. We examined the prevalence of overweight, anthropometric changes, and the effect of methylphenidate treatment in 275 children with ADHD without neurological comorbidities and in controls. Data we...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073810380051
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:We developed and validated a Spanish seizure screen for children based on a previously validated English seizure screen that could be administered by a trained research assistant in a 2-step process, approximating the clinical diagnostic process of a pediatric epilepsy specialist. This questionnaire was desi...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820978001
更新日期:2020-12-18 00:00:00
abstract::The purpose of this study was to determine which clinical characteristics correlated with abnormal computed tomographic (CT) scans in epileptic children. Thirty variables were examined. Of these, four variables (presence of inherited or congenital disease, focal motor findings, developmental delay, and early onset of ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388600100210
更新日期:1986-04-01 00:00:00
abstract::Apneic neonatal seizures can present as apparent life-threatening events. We report a newborn with unexplained episodes of apnea associated with cyanosis and desaturation, starting on the first day postpartum. Biochemical tests were normal. Central nervous system infections as well as abnormalities of upper airways an...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813481403
更新日期:2014-07-01 00:00:00
abstract::The voltage-sensitive calcium channel probe 125I-omega-GVIA conotoxin has been shown to be a developmental marker in whole brain preparations of Swiss Webster mice. The present study looks more carefully at regional dissections of the mouse brain (cerebrum, cerebellum, and brain stem) at postnatal day 8 and postnatal ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389400900120
更新日期:1994-01-01 00:00:00
abstract::The purpose of this survey and record review was to characterize emergency department management of unprovoked seizures and status epilepticus in children in Illinois. The survey was sent to 119 participating emergency departments in the Emergency Medical Services for Children program; responses were received from 103...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814566626
更新日期:2015-10-01 00:00:00
abstract::Patients with partial seizures aged 1 week to 19 years (n = 175) were included in several prospective vigabatrin studies at the hospital Saint Vincent de Paul. A decrease in seizure frequency of over 50% was achieved in 70% of patients, with 30% becoming seizure free, and only 6% experiencing an increase. Tuberous scl...
journal_title:Journal of child neurology
pub_type: 临床试验,杂志文章
doi:10.1177/088307389701200304
更新日期:1997-04-01 00:00:00
abstract::There is increased necessity to focus research on school-aged athletes with sports-related concussion (SRC). This study assessed differences in symptom reporting and neurocognitive performance in youth athletes who sustained a sports-related concussion. A total of 1345 concussed and 3529 nonconcussed athletes (ages 8-...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073818766815
更新日期:2018-06-01 00:00:00
abstract::A 13-month-old boy presented with repeated episodes of tongue biting during sleep. On evaluation, he was found to have hereditary chin trembling, a rare autosomal dominant condition characterized by continuous or intermittent tremulous activity of the mentalis muscle. This is the first report of this kind from India. ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738060210111101
更新日期:2006-11-01 00:00:00
abstract::The electrophysiologic findings in an infant with congenital facial diplegia (Möbius syndrome) are presented. As to serial electrically elicited blink reflexes, the R1 amplitude was significantly reduced and the R2 latency was significantly prolonged. The M response of the orbicularis oculi muscle showed slightly redu...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389300800213
更新日期:1993-04-01 00:00:00
abstract::Autosomal recessive spinal muscular atrophy is caused by mutations in the survival motoneuron (SMN) gene. There are two nearly identical copies of this gene present on chromosome 5q13; however, only the telomeric copy of this gene is affected in spinal muscular atrophy. In this study, we describe a new method to detec...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738030180041301
更新日期:2003-04-01 00:00:00
abstract::Paramyotonia congenita in 22 members of Arab (Omani) family is reported. Four generations were affected. All had early onset around 1 year of age, with myotonia and cold intolerance. Age of onset in the index case was at 3 months of age. Six members with the disease were examined and investigated. To our knowledge, th...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808330185
更新日期:2010-02-01 00:00:00
abstract:AIM:We characterize the pediatric postural orthostatic tachycardia syndrome (POTS) population seen at a single tertiary care referral center. METHOD:Retrospective chart review of all pediatric POTS patients seen in our center between 2015 and 2017. Pediatric POTS was defined as chronic, at least 3 months, symptoms of ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820916260
更新日期:2020-07-01 00:00:00
abstract::Multiple sclerosis onset in youth is increasingly recognized. A systematic review was conducted to assess incidence and prevalence of pediatric-onset multiple sclerosis, focusing on occurrence by age subgroups and disease course. A literature search for the period 1965-2018 was carried out, selecting population-based ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073819845827
更新日期:2019-10-01 00:00:00
abstract::The purpose of this study was to assess the cognitive development of 27 children with nonhemorrhagic neonatal stroke (occurring within the first 28 days of life). The cognitive evaluation consisted of the Bayley Scales of Infant Development, administered at 12 and/or 24 months poststroke. Compared with the normative s...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073807305784
更新日期:2007-09-01 00:00:00
abstract::To evaluate the consistency of the Hammersmith Infant Neurological Examination scores of very-low-birth-weight infants at 6 and 12 months of age and its correlation to cranial ultrasonography findings, we designed a prospective study between January 2005 and January 2008, in the tertiary Neonatal Unit of Aristotle Uni...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813479171
更新日期:2014-11-01 00:00:00
abstract::The clinical and laboratory data of four pediatric patients and one adult patient with inverted duplication (inv dup) (15) are reported. The most evident findings were dysmorphic features with frontal bossing; genital abnormalities, such as macropenis or hypospadias; mental retardation; autistic behavior; and seizures...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380001500605
更新日期:2000-06-01 00:00:00
abstract::We previously reported that patients with spinal muscular atrophy do not lose muscle strength over time as measured quantitatively. However, we noted that many patients with spinal muscular atrophy suffer from what they call fatigue. We wondered if we could measure fatigue during a single maximal voluntary contraction...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389701200507
更新日期:1997-08-01 00:00:00
abstract::Rett Syndrome is known to occur in females, around the second year, with loss of hand use, onset of stereotypes and acquired microcephaly. Such regression is often very rapid, but this has never been documented. In one of our patients, photographs taken at different times clearly demonstrate the rapid progression of f...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389901400815
更新日期:1999-08-01 00:00:00
abstract::To identify early predictive factors of outcome in childhood epilepsy, the case records of all children with new-onset epilepsy presenting to a single neurology practice over a 10-year interval were reviewed. Only children with more than 2 years of follow-up were included. Cox regression analysis was used to identify ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738050200110701
更新日期:2005-11-01 00:00:00
abstract::The influence of severity of closed head injury and age on attentional functioning was prospectively investigated in 36 children (age range, 7 to 16 years) 6 months after injury. Children were placed into mild, moderate, and severe injury groups using established neurologic criteria. Each child received the Wechsler I...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389300800410
更新日期:1993-10-01 00:00:00