Abstract:
:The purpose of this study was to determine which clinical characteristics correlated with abnormal computed tomographic (CT) scans in epileptic children. Thirty variables were examined. Of these, four variables (presence of inherited or congenital disease, focal motor findings, developmental delay, and early onset of seizures) correlated with CT scan outcome. Partial seizures per se were not highly associated with abnormal CT scans. A crude decision rule based on these results correctly classified the CT scan result in 94% of the patients who were clinically predicted not to have a parenchymal abnormality.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Koprowski C,Clancy Rdoi
10.1177/088307388600100210subject
Has Abstractpub_date
1986-04-01 00:00:00pages
145-8issue
2eissn
0883-0738issn
1708-8283journal_volume
1pub_type
杂志文章abstract::Pelizaeus-Merzbacher disease and X-linked spastic paraplegia type 2 are two sides of the same coin. Both arise from mutations in the gene encoding myelin proteolipid protein. The disease spectrum for Pelizaeus-Merzbacher disease and spastic paraplegia type 2 is extraordinarily broad, ranging from a spastic gait in the...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/08830738030180090801
更新日期:2003-09-01 00:00:00
abstract::The aim of this study is to investigate the efficacy and tolerability of topiramate in a large number of children with West syndrome. The authors performed a retrospective, questionnaire-based data collection in specialized epilepsy units in Germany. Patients with West syndrome and hypsarrhythmia could be included if ...
journal_title:Journal of child neurology
pub_type: 杂志文章,多中心研究
doi:10.1177/0883073807300535
更新日期:2007-03-01 00:00:00
abstract::Pediatric headache patients often experience significant sleep disturbance, which may be a risk factor for poor physical, academic, and emotional functioning, including increased anxiety/fear. The current retrospective cohort study of a clinical sample of youth with persistent headache aimed to examine the impact of s...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073819887597
更新日期:2020-03-01 00:00:00
abstract:AIM:The present study aimed to investigate whether the response variability of infants to modified constraint-induced movement therapy and bimanual therapy are associated with different types of brain lesions. METHOD:Infants with unilateral cerebral palsy (N = 22) ages 8-15 months (mean = 10.95, standard deviation = 2...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073818801632
更新日期:2018-12-01 00:00:00
abstract::Our experience with two children with Joubert syndrome demonstrates how the diagnosis, if suspected by recognition of the behavioral phenotype, can rapidly be made by employing cranial sonography. This technique also may afford prenatal diagnosis of the syndrome in future siblings of confirmed cases. We have produced ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388800300403
更新日期:1988-10-01 00:00:00
abstract::Ketogenic therapy is now an accepted treatment for pediatric and adult patients with medically refractory epilepsy.1-3 However, young adults treated with a ketogenic diet face unique challenges when transitioning to adult neurology providers.4 The variable acceptance of dietary therapy, paucity of nutritionists and ad...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820938587
更新日期:2020-11-01 00:00:00
abstract::The outcomes of children with cryptogenic seizures most probably arising from the frontal lobe are difficult to predict. We retrospectively collected data on 865 pediatric patients with epilepsy. In 78 patients with cryptogenic frontal lobe epilepsy, the age at first seizure was inversely correlated with the outcome, ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813511855
更新日期:2014-12-01 00:00:00
abstract::Basilar artery occlusion in children is rare. The clinical diagnosis of basilar artery occlusion is often difficult because the initial neurologic findings, most frequently hemiparesis, involuntary movements, or headache, are often transient and can suggest complicated migraine, seizures, or both. We have reviewed 37 ...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/08830738030180070601
更新日期:2003-07-01 00:00:00
abstract::Autism is characterized by social deficits, communication and language impairments, narrow restricted interests, repetitive behaviors, inattention, and hyperactivity. While selective serotonin reuptake inhibitors have demonstrated efficacy in treating core symptoms of autism, norepinephrine reuptake inhibitors have de...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380001500214
更新日期:2000-02-01 00:00:00
abstract::Intracranial tumors are the most common solid tumors in children. The infratentorial compartment will be the primary site for 60% to 70% of these tumors, including astrocytomas, medulloblastomas, and ependymomas. Several technological advancements have increased our knowledge of the cell biology of pediatric brain tum...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073808321768
更新日期:2008-10-01 00:00:00
abstract::Despite remarkable growth in the clinical neurology literature, there is little research on peer review and biomedical publication in neurology. Biomedical publication research encompasses every step of the research process, from the methodology to the publication of research findings. Some general medical journals ha...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073810374647
更新日期:2010-10-01 00:00:00
abstract::To determine the yield of neuroimaging in children presenting to the emergency department with acute ataxia in the post-varicella vaccine era, we conducted a cross-sectional study between 1995 and 2013 at a single pediatric tertiary care center. We included children aged 1-18 years evaluated for acute ataxia of <7 day...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814561300
更新日期:2015-09-01 00:00:00
abstract::Duchenne muscular dystrophy results in a broad spectrum of physical and psychosocial consequences, both to patient and caregivers. This study was aimed to explore health-related quality of life and its possible determinants in Duchenne muscular dystrophy children and in their parents. Caregivers (21 mothers and 6 fath...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073810389043
更新日期:2011-06-01 00:00:00
abstract::The aim of this study was to investigate the clinical, demographic, and electromyographic (EMG) characteristics of 12 earthquake victims in the pediatric age group and to compare the findings with those of the adult group. Following the 1999 Marmara earthquake, 75 subjects with suspected peripheral nerve injury were r...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738050200030701
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and tolerability of adjunctive eslicarbazepine acetate (ESL) in pediatric patients (aged 4-17 years) with refractory focal seizures. METHODS:Pooled safety data from patients aged 4-17 years in Study 208 (NCT01527513) and Study 305 (NCT00988156) were analyzed. Both were randomized, doub...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073819890997
更新日期:2020-03-01 00:00:00
abstract::There is increased necessity to focus research on school-aged athletes with sports-related concussion (SRC). This study assessed differences in symptom reporting and neurocognitive performance in youth athletes who sustained a sports-related concussion. A total of 1345 concussed and 3529 nonconcussed athletes (ages 8-...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073818766815
更新日期:2018-06-01 00:00:00
abstract::Vibratory feedback can be a useful tool for rehabilitation. We examined its use in children with dystonia to understand how it affects muscle activity in a population that does not respond well to standard rehabilitation. We predicted scaled vibration (ie, vibration that was directly or inversely proportional to muscl...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073816671830
更新日期:2017-02-01 00:00:00
abstract::Neurologic toxicity may occur as a direct effect of cancer and its therapy or indirectly because of a dysfunctional immune system. The authors report the development of axonal neuropathy, myelopathy, and leucoencephalopathy associated with glutamic acid decarboxylase-65 (GAD) antibodies in 4 children with progressive ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808315617
更新日期:2008-11-01 00:00:00
abstract::There are scarce reports of childhood stroke from China. Our objective was to describe the clinical spectrum, risk factors, and imaging characteristics of childhood stroke in China. Using a hospital discharge database, children with stroke who were first admitted from 2002 to 2011 were retrospectively enrolled. We ide...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814538667
更新日期:2015-03-01 00:00:00
abstract::Amyotrophic lateral sclerosis is a fatal neurodegenerative disease. Epidemiologic data suggest that malnutrition is a common feature in amyotrophic lateral sclerosis and being overweight or obese confers a survival advantage in this patient population. In amyotrophic lateral sclerosis mouse models, a high-fat diet has...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813488669
更新日期:2013-08-01 00:00:00
abstract::High-dose phenobarbital therapy is an effective treatment for refractory status epilepticus in children. The advantages of this therapy include milder adverse effects without limits for maximal phenobarbital levels or doses during the initial phase of treatment. However, little is known about the safety of continuing ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808331360
更新日期:2009-12-01 00:00:00
abstract::Sydenham's chorea results from group A streptococcus infection and subsequent generation of antineuronal antibodies directed at the caudate nucleus and putamen. Predominantly bilateral, in up to 30% of cases the chorea can be unilaterally restricted. Imaging studies, both structural (magnetic resonance imaging) and fu...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389901400805
更新日期:1999-08-01 00:00:00
abstract::We describe the brain magnetic resonance imaging (MRI) findings in eight neonates with tuberous sclerosis complex to further delineate the spectrum of characteristic findings in these patients. In addition to the previously described characteristic brain MRI findings in neonates, which included cortical tuber, transma...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738060210042301
更新日期:2006-04-01 00:00:00
abstract::Spinal muscular atrophy type 0 is a severe form of spinal muscular atrophy that is usually fatal in the first months of life. These children present with arthrogryposis multiplex congenita and respiratory compromise. We describe a child with spinal muscular atrophy and arthrogryposis multiplex congenita who has had a ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101601213
更新日期:2001-12-01 00:00:00
abstract::An association between overweight and attention-deficit/hyperactivity disorder (ADHD) in children was previously suggested. We examined the prevalence of overweight, anthropometric changes, and the effect of methylphenidate treatment in 275 children with ADHD without neurological comorbidities and in controls. Data we...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073810380051
更新日期:2011-03-01 00:00:00
abstract::Many neurodegenerative diseases can be misdiagnosed as cerebral palsy. The correct diagnosis is reached when the condition recurs in families or when there are specific clinical signs. The clinical and imaging features of 3 children, from 2 unrelated families, presenting with global developmental delay and dystonia ar...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073813512026
更新日期:2014-11-01 00:00:00
abstract::We report a 6-month-old boy with diffuse hypertonia and developmental delay who had unilateral separated-lip schizencephaly and contralateral polymicrogyria. The contralateral polymicrogyria was associated with an incomplete clefting in that hemisphere. An umbilical cord hamartoma is presumed to have caused hypoperfus...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738030180031401
更新日期:2003-03-01 00:00:00
abstract::This is the first study to evaluate the efficacy of riboflavin for migraine prophylaxis in children. This was a randomized, double-blind study of riboflavin (200 mg daily) versus placebo in 48 children. The primary efficacy measure was the number of patients achieving a 50% or greater reduction in the number of migrai...
journal_title:Journal of child neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/0883073808318053
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:The objectives were to investigate the relationship between ketogenic diet therapy and neutropenia in children with epilepsy. METHODS:A retrospective chart review of children who initiated ketogenic diet at the Hospital for Sick Children between January 1, 2000, and May 1, 2018 was performed. Factors associ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820984067
更新日期:2021-01-04 00:00:00
abstract::We describe the clinical utility of echo-planar diffusion-weighted imaging in neonatal cerebral infarction. Eight full-term neonates aged 1 to 8 days referred for neonatal seizures were studied. Patients were followed for a mean of 17 months with detailed neurologic examinations at regular intervals. Head computed tom...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380001500905
更新日期:2000-09-01 00:00:00