Abstract：
:The aim of this study was to clarify the relationship between neurologic findings and outcome of patients with West syndrome, focusing on the popliteal angle. The complete neurologic examination, including an assessment of the popliteal angle and muscle tone, was performed on 45 patients with West syndrome. A tight popliteal angle was determined when it was 120 degrees or less. In all 45 patients, abnormal muscle tone was not correlated with any variables. A tight popliteal angle was correlated with seizure persistence, cerebral palsy, and abnormality on magnetic resonance imaging (MRI), as well as severe developmental delay. When limited to the patients with developmental delay, a tight popliteal angle was correlated with severe developmental delay, cerebral palsy, and MRI abnormality, although abnormal muscle tone was not correlated with any items. In the delay group, eight patients had a tight popliteal angle with normal muscle tone. Among them, severe developmental delay was seen in seven (88%), seizure persistence in five (63%), and MRI abnormality in five (63%). These results suggest that a tight popliteal angle might be an indicator of poor neurologic outcome in patients with West syndrome.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Okumura A,Kato T,Sei Y,Suzuki T,Morishita Y,Watanabe Kdoi
10.1177/08830738060210101801subject
Has Abstractpub_date
2006-10-01 00:00:00pages
898-900issue
10eissn
0883-0738issn
1708-8283journal_volume
21pub_type
杂志文章abstract：:Managing severe epilepsy syndromes of early childhood is challenging as the seizures are typically resistant to treatment and may cause disabling mental and behavioral problems in later life. A comprehensive treatment plan includes pharmacologic, nonpharmacologic, and surgical options. This article reviews clinical st...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/0883073809338153
更新日期：2009-08-01 00:00:00
abstract：:Nonconvulsive status epilepticus is a prolonged and continuous state of increased unawareness without overt motor seizures linked with repetitive generalized epileptic discharges. In children, it may occur de novo but more commonly may complicate a preexisting epileptic disorder. We report on a 2-year-old female who p...
journal_title：Journal of child neurology
pub_type： 杂志文章
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abstract：:Paramyotonia congenita in 22 members of Arab (Omani) family is reported. Four generations were affected. All had early onset around 1 year of age, with myotonia and cold intolerance. Age of onset in the index case was at 3 months of age. Six members with the disease were examined and investigated. To our knowledge, th...
journal_title：Journal of child neurology
pub_type： 杂志文章
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更新日期：2010-02-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073816664670
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abstract：:Narcolepsy with cataplexy is a severely disabling disorder very often arising in childhood. Data on neuropsychological impairment in children are scant. We administered standardized neuropsychological tests to 13 children with narcolepsy with cataplexy. Overall, our patients displayed multiple patterns of cognitive an...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073813508315
更新日期：2014-10-01 00:00:00
abstract：:Idiopathic "benign" intracranial hypertension is an uncommon but important cause of headache that can lead to visual loss. This study was undertaken to review our experience in the diagnosis and management of idiopathic intracranial hypertension, giving special attention to treatments used. A retrospective chart revie...
journal_title：Journal of child neurology
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更新日期：2001-07-01 00:00:00
abstract：:The level of parental stress in families of children with autism and other developmental disabilities and its association with child comorbid symptoms was studied in an ethnically diverse population, in a cross-sectional study with structured interview. The sample included 50 families of children with autism and 50 fa...
journal_title：Journal of child neurology
pub_type： 杂志文章
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journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307380101600819
更新日期：2001-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the safety and tolerability of adjunctive eslicarbazepine acetate (ESL) in pediatric patients (aged 4-17 years) with refractory focal seizures. METHODS:Pooled safety data from patients aged 4-17 years in Study 208 (NCT01527513) and Study 305 (NCT00988156) were analyzed. Both were randomized, doub...
journal_title：Journal of child neurology
pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073809336130
更新日期：2010-01-01 00:00:00
abstract：:Möbius' syndrome is a rare congenital anomaly characterized by paralysis of the 7th and other cranial nerves and musculoskeletal abnormalities. We report a patient with Möbius' syndrome associated with arthrogryposis and mega cisterna magna in addition to the classic components of this syndrome. The case is interestin...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738040190010710
更新日期：2004-01-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073814546687
更新日期：2015-08-01 00:00:00
abstract：:To describe associated ocular, neurologic, and systemic findings in a population of children with optic nerve hypoplasia, a retrospective chart review of 100 patients with optic nerve hypoplasia for the presence of neurologic, radiologic, and endocrine abnormalities was performed. Neuroimaging and endocrine studies we...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738060210111701
更新日期：2006-11-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389200700214
更新日期：1992-04-01 00:00:00
abstract：:Ethical problems related to intensive care of extremely preterm newborns of < or = 25 weeks' gestational age and at risk of disability have been extensively debated. The Bioethical Committee of the Department of Paediatrics of the University Hospital of Padua organized and started a multidisciplinary group to release ...
journal_title：Journal of child neurology
pub_type： 指南,杂志文章,实务指引
doi：10.1177/088307380401900106011
更新日期：2004-01-01 00:00:00
abstract：:Children and adolescents with the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) diagnosis of attention-deficit hyperactivity disorder (ADHD) can have comorbid conditions such as conduct disorder, oppositional defiant disorder, and obsessive-compulsive disorder (comorbid type). The purpose of our st...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738040190020201
更新日期：2004-02-01 00:00:00
abstract：:Understanding patterns of medical comorbidity in attention-deficit/hyperactivity disorder (ADHD) may lead to better treatment of affected individuals as well as aid in etiologic study of disease. This article provides the first systematic evaluation on the medical comorbidity of ADHD in a nationally representative sam...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073816653782
更新日期：2016-10-01 00:00:00
abstract：UNLABELLED:This study evaluates whether the literature-reported potential predictors can predict the outcome of multilevel botulinum toxin A injections in children who walk with flexed knees. The associations between 11 different predictors and 2 different outcome measures (the Gross Motor Function Measure and knee ang...
journal_title：Journal of child neurology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1177/0883073807313039
更新日期：2008-06-01 00:00:00
abstract：:Autosomal recessive spinal muscular atrophy is caused by mutations in the survival motoneuron (SMN) gene. There are two nearly identical copies of this gene present on chromosome 5q13; however, only the telomeric copy of this gene is affected in spinal muscular atrophy. In this study, we describe a new method to detec...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738030180041301
更新日期：2003-04-01 00:00:00
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journal_title：Journal of child neurology
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更新日期：1991-04-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章,评审
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更新日期：1997-11-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章
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更新日期：2003-06-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章,多中心研究
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更新日期：1992-10-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章,评审
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更新日期：1990-07-01 00:00:00
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更新日期：2000-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-06-01 00:00:00
