Abstract:
UNLABELLED:This study evaluates whether the literature-reported potential predictors can predict the outcome of multilevel botulinum toxin A injections in children who walk with flexed knees. The associations between 11 different predictors and 2 different outcome measures (the Gross Motor Function Measure and knee angle at midstance) at different weeks of follow-up were studied in 46 children with cerebral palsy (age 4-12 years), using regression analysis. Only age was positively associated with change in the Gross Motor Function Measure at 12 weeks, and only ankle angle at midstance was positively associated with change in knee angle at midstance at 48 weeks. Of these, only the former association was found to be clinically relevant. CONCLUSION:The majority of potential predictors do not predict the outcome of multilevel botulinum toxin A injections in this patient group. The only relevant significant predictor, with regard to gross motor function, is older age.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Scholtes VA,Dallmeijer AJ,Becher JGdoi
10.1177/0883073807313039subject
Has Abstractpub_date
2008-06-01 00:00:00pages
628-34issue
6eissn
0883-0738issn
1708-8283pii
0883073807313039journal_volume
23pub_type
杂志文章,多中心研究,随机对照试验abstract::This is a case report of an otherwise healthy 2-year-old boy with a history of pica, associated with iron deficiency anemia. This boy was referred to our department for a neurologic evaluation because of an acute episode of sialorrhea, difficulty in speaking, dysphagia, and repeated swallowing movements. An uncertain ...
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