Bone turnover markers in serum and periodontal microenvironments.

abstract：BACKGROUND AND OBJECTIVE:High-mobility-group box 1 functions as a late-phase inflammatory mediator. It can be released extracellularly by macrophages and necrotic cells through lipopolysaccharide and tumor necrosis factor-alpha. The objective of this study was to clarify the source of high-mobility-group box 1 in chron...

journal_title：Journal of periodontal research

authors： Morimoto Y,Kawahara KI,Tancharoen S,Kikuchi K,Matsuyama T,Hashiguchi T,Izumi Y,Maruyama I

更新日期：2008-02-01 00:00:00

abstract：:Using the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining technique, we investigated ultrastructural localization of sulfated glycosaminoglycans (GAGs) in the rat gingiva shortly after eruption, especially those associated with internal and external basal laminae. In the apical portion of ...

journal_title：Journal of periodontal research

authors： Kogaya Y,Haruna S,Vojinovic J,Iwayama Y,Akisaka T

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the presence of factor XIIIa+ dendritic cells and S-100 protein+ Langerhans' cells in the gingival epithelium and connective tissue of periodontal pockets, before and after non-surgical periodontal therapy. BACKGROUND:The microbial flora in periodontal pockets provok...

journal_title：Journal of periodontal research

authors： Dereka XE,Tosios KI,Chrysomali E,Angelopoulou E

更新日期：2004-12-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00

abstract：:Ketoprofen creams were evaluated for the treatment of periodontal disease in a placebo-controlled, double-blind study in the rhesus monkeys, Macaca mulatta. Two formulations containing ketoprofen (1%), with or without vitamin E, were evaluated against appropriate controls (8 monkeys per group). Two weeks prior to trea...

journal_title：Journal of periodontal research

authors： Li KL,Vogel R,Jeffcoat MK,Alfano MC,Smith MA,Collins JG,Offenbacher S

更新日期：1996-11-01 00:00:00

abstract：:Glycosaminoglycans in normal and cyclosporin-induced gingival overgrowth were extracted by papain digestion and purified by Mono Q-FPLC chromatography. The purified glycosaminoglycans were analyzed by agarose gel electrophoresis and by the pattern of degradation products formed by chondroitin lyases on HPLC chromatogr...

journal_title：Journal of periodontal research

authors： Rocha LA,Martins RC,Werneck CC,Feres-Filho EJ,Silva LC

更新日期：2000-06-01 00:00:00

abstract：:Thirteen periodontally healthy subjects were monitored clinically for 6-12 months. Clinical measurements at 6-weekly intervals included duplicate PD measurements, presence of plaque, redness, and bleeding on probing. Baseline measurements consisted of 2 visits 1 wk apart. Microbial samples were taken from 11 of the su...

journal_title：Journal of periodontal research

authors： Tanner A,Kent R,Maiden MF,Taubman MA

更新日期：1996-04-01 00:00:00

abstract：:Collagenolysis in periodontitis is thought to be modulated by the expression of three genes, collagenase, tissue inhibitors of metalloproteinases-1 and -2 (TIMP-1 and -2). We assessed the possible difference in TIMP-1, TIMP-2 and collagenase mRNA levels between gingival samples from patients with periodontitis and tho...

journal_title：Journal of periodontal research

authors： Nomura T,Takahashi T,Hara K

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Nicotine, the main psychoactive component of tobacco, affects cell metabolism, proliferation, adhesion and, importantly, the osteogenic differentiation of fibroblasts. Approximately 15% of all orthodontic patients are adults among who one-fifth are smokers. Hence, it is necessary to have insig...

journal_title：Journal of periodontal research

authors： Yu W,Hu B,Shi X,Cao Z,Ren M,He Z,Lin J,Deng H,Hu R

更新日期：2018-08-01 00:00:00

abstract：:The 3 human salivary cystatins S, SA and SN are multifunctional proteins that possess a cysteine protease inhibitory property, but their ability to act as such is very different (SN > SA > S). One form, S, also appears to possess antibacterial properties towards the bacterium Porphyromonas gingivalis, often associated...

journal_title：Journal of periodontal research

authors： Baron AC,Gansky SA,Ryder MI,Featherstone JD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Factors such as vascularization of the periodontium, inflammatory reactions and immune response affect the oral environment and ecology, decreasing host resistance and promoting the development of symptoms and the advancement of periodontal disease. Fatigue also influences the hypothalamic-pitu...

journal_title：Journal of periodontal research

authors： Nakada T,Kato T,Numabe Y

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVES AND BACKGROUND:Endothelin-1 (ET-1) is a 21-amino acid peptide with multifunctional regulation. ET-1 expresses in various cells during inflammation. The present study aimed to examine the ET-1 expression in oral epithelial cells after infection with the periodontal pathogen and to investigate the presence of ...

journal_title：Journal of periodontal research

authors： Yamamoto E,Awano S,Koseki T,Ansai T,Takehara T

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Tobacco use is associated with increased periodontal destruction in both cigarette smokers and smokeless tobacco users. Gingival keratinocytes are the first cells in contact with microbial and tobacco components and play a key role in the innate immune response to these agents. The objective of...

journal_title：Journal of periodontal research

authors： Johnson GK,Guthmiller JM,Joly S,Organ CC,Dawson DV

更新日期：2010-08-01 00:00:00

abstract：:To investigate the effect of lipopolysaccharide (LPS) on phagocytic activity of collagen fibrils by periodontal fibroblasts, we studied rat molar gingival connective tissue and periodontal ligament under light and electron microscopy after topical application of LPS (5 mg/ml in physiological salt solution (PS)) on the...

journal_title：Journal of periodontal research

authors： Ijuhin N,Miyauchi M,Ito H,Takata T,Ogawa I,Nikai H

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The jaw bone, unlike most other bones, is derived from neural crest stem cells, so we hypothesized that it may have different characteristics to bones from other parts of the body, especially in the nature of its periosteum. The periosteum exhibits osteogenic potential and has received consider...

journal_title：Journal of periodontal research

authors： Ichikawa Y,Watahiki J,Nampo T,Nose K,Yamamoto G,Irie T,Mishima K,Maki K

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Connective tissue grafts are frequently applied, together with Emdogain(®) , for root coverage. However, it is unknown whether fibroblasts from the gingiva and from the palate respond similarly to Emdogain. The aim of this study was therefore to evaluate the effect of Emdogain(®) on fibroblasts...

journal_title：Journal of periodontal research

authors： Gruber R,Stähli A,Miron RJ,Bosshardt DD,Sculean A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Treponema denticola is a key pathogen associated with periodontitis, a chronic inflammatory disease affecting tooth-supporting tissues. In the present study, we investigated the response of human macrophage-like cells to stimulation by peptidoglycan isolated from T. denticola. We also studied t...

journal_title：Journal of periodontal research

authors： Tanabe SI,Bodet C,Grenier D

更新日期：2009-08-01 00:00:00

abstract：:The diagnosis of periodontal disease is commonly based on objective evaluations of the patient's medical/dental history as well as clinical and radiographic examinations. However, periodontal disease should also be evaluated subjectively through measures that quantify its impact on oral health-related quality of life....

journal_title：Journal of periodontal research

authors： Ferreira MC,Dias-Pereira AC,Branco-de-Almeida LS,Martins CC,Paiva SM

更新日期：2017-08-01 00:00:00

abstract：:It has been assumed that there is a relationship between periodontal diseases and diabetes mellitus, however the putative periodontal microorganisms in non-diabetes mellitus (non-DM) individuals and non-insulin-dependent diabetes mellitus (NIDDM) patients have not been well studied. In this study, the detection rates ...

journal_title：Journal of periodontal research

authors： Yuan K,Chang CJ,Hsu PC,Sun HS,Tseng CC,Wang JR

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether a peptide-based coating can prevent the adhesion of Porphyromonas gingivalis, a key human pathogen associated with periodontitis and peri-implantitis. BACKGROUND:Nonsurgical and surgical interventions have been used for the treatment of peri-implantitis; howe...

journal_title：Journal of periodontal research

authors： Fang D,Yuran S,Reches M,Catunda R,Levin L,Febbraio M

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study analyzed the interaction of Porphyromonas gingivalis ATCC 33277 and Aggregatibacter actinomycetemcomitans Y4 with peripheral blood polymorphonuclear neutrophils taken from patients with aggressive periodontitis and chronic periodontitis. MATERIAL AND METHODS:Peripheral blood polymor...

journal_title：Journal of periodontal research

authors： Guentsch A,Puklo M,Preshaw PM,Glockmann E,Pfister W,Potempa J,Eick S

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Long-term tooth retention is the ultimate goal of periodontal therapy. Aim of this study was to evaluate tooth loss (TL) during 10 years of supportive periodontal therapy (SPT) in periodontal compromised patients and to identify factors influencing TL on patient level. MATERIAL AND METHODS:Pat...

journal_title：Journal of periodontal research

authors： Petsos H,Schacher B,Ramich T,Nickles K,Dannewitz B,Arendt S,Seidel K,Eickholz P

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Recent epidemiological studies have shown that individuals with periodontitis have a significantly increased risk of developing coronary heart disease. In addition to conventional risk factors, chronic infection and subsequent production of systemic inflammatory markers may be associated with this increased ...

journal_title：Journal of periodontal research

authors： Yamazaki K,Honda T,Oda T,Ueki-Maruyama K,Nakajima T,Yoshie H,Seymour GJ

更新日期：2005-02-01 00:00:00

abstract：:The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans, a periodontal pathogen, is a newly described cytotoxin with immunosuppressive properties, capable of causing cell cycle arrest of lymphocytes. The objectives of this study were to investigate the occurrence of A. actinomycetemcomitans with ...

journal_title：Journal of periodontal research

authors： Tan KS,Song KP,Ong G

更新日期：2002-08-01 00:00:00

abstract：:Diploid fibroblasts obtained from explants of human gingiva and maintained in vitro undergo a several-fold decrease in protein and collagen synthesis as a function of increasing donor age. Using drug-induced gingival hyperplasia as a model, we performed experiments to learn whether fibroblasts derived from hyperplasti...

journal_title：Journal of periodontal research

authors： Johnson BD,Narayanan AS,Pieters HP,Page RC

更新日期：1990-03-01 00:00:00

abstract：:This paper reviews the literature on prepubertal periodontitis (PP) according to the definition and the classification of PP by Page. The generalized form of PP (G-PP) defined by Page was identified as the oral manifestation of a systemic disease called leukocyte adhesion deficiency (LAD) and thus the pathogenesis is ...

journal_title：Journal of periodontal research

authors： Watanabe K

更新日期：1990-01-01 00:00:00

abstract：:Portions of clinically healthy non-keratinized and keratinized oral epithelia were removed from adult vervet monkeys (Cercopithecus aethiops). The epithelium was separated from the underlying lamina propria by trypsin digestion, following which the epithelial cells were separated from the various epithelial layers. ...

journal_title：Journal of periodontal research

authors： Cleaton-Jones P

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the oral cavity, the mucosal tissues may develop a number of different pathological conditions, such as inflammatory diseases (gingivitis, periodontitis) and autoimmune disorders (eg, oral lichen planus) that require therapy. The application of topical drugs is one common therapeutic approa...

journal_title：Journal of periodontal research

authors： Jager J,Obst K,Lohan SB,Viktorov J,Staufenbiel S,Renz H,Unbehauen M,Haag R,Hedtrich S,Teutloff C,Meinke MC,Danker K,Dommisch H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Ciclosporin A (CsA)-induced gingival overgrowth is attributed to an exaggerated accumulation of extracellular matrix, which is mainly due to an increased expression of transforming growth factor-β1 (TGF-β1). Herein, the in vitro investigation of effects of overexpression of Smad7, a TGF-β1 sign...

journal_title：Journal of periodontal research

authors： Sobral LM,Aseredo F,Agostini M,Bufalino A,Pereira MC,Graner E,Coletta RD

更新日期：2012-04-01 00:00:00

abstract：:The characteristic hemagglutination (HA) of Leptotrichia buccalis was used for measuring its attachment to various human cells and for determining if saliva contained hemagglutination inhibition (HI) factors. The microbial strain utilized displayed the characteristic EM morphology of L. buccalis. Sonicated preparation...

journal_title：Journal of periodontal research

authors： Falkler WA Jr,Hawley CE,Mongiello JR

更新日期：1978-09-01 00:00:00