Intracranial myxopapillary ependymoma: case report.

abstract：:Various histological types of tumors arise in the pineal region. The most common tumors are pineal parenchymal tumors and germ cell tumors. Pineal parenchymal tumors are divided into pineocytoma, pineal parenchymal tumor with intermediate differentiation and pineoblastoma. Pineocytomas are well-differentiated tumors a...

journal_title：Journal of neuro-oncology

authors： Hirato J,Nakazato Y

更新日期：2001-09-01 00:00:00

abstract：:This study retrospectively reviewed our single institute experience to clarify the optimal indication and timing of salvage surgery. Retrospective analysis of 159 consecutive cases with germ cell tumors identified 20 cases with salvage surgery. These cases were classified based on the radiological response to neoadjuv...

journal_title：Journal of neuro-oncology

authors： Kanamori M,Kumabe T,Watanabe M,Chonan M,Saito R,Yamashita Y,Ogawa Y,Sonoda Y,Tominaga T

更新日期：2018-07-01 00:00:00

abstract：:This review identifies the current literature on the use of bevacizumab for cerebral radiation necrosis in patients with high-grade gliomas, summarizes the clinical course and complications following bevacizumab, and discusses the relative costs and benefits of this therapeutic option. A Medline search was conducted o...

journal_title：Journal of neuro-oncology

authors： Lubelski D,Abdullah KG,Weil RJ,Marko NF

更新日期：2013-12-01 00:00:00

abstract：:A major toxic effect of the chemotherapeutic agents paclitaxel and cisplatin is peripheral neuropathy. We report the use of a rat model of cytotoxic neuropathy to evaluate the role of glutamate as a possible neuroprotectant for these two drugs. Neuropathy was manifest as gait disturbance in 100% of paclitaxel treated ...

journal_title：Journal of neuro-oncology

authors： Boyle FM,Wheeler HR,Shenfield GM

更新日期：1999-01-01 00:00:00

abstract：:To investigate the underlying intratumoral diversity of molecular profiles in glioblastomas, a proteomic approach was introduced to compare samples from regions of different histological grade. Using two-dimensional gel electrophoresis (2DE) with matrix-assisted laser-desorption/ionization time-of-flight mass spectrom...

journal_title：Journal of neuro-oncology

authors： Park CK,Jung JH,Park SH,Jung HW,Cho BK

更新日期：2009-08-01 00:00:00

abstract：:The effectiveness of temozolomide (TMZ) dosing schemes and the "rechallenge" of recurrent glioblastoma (GBM) with TMZ are controversial. We therefore compared the efficacy of different TMZ dosing schemes against GBM cancer stem cell (CSC) lines in vitro. In O(6)-methyl-guanidine-methyl-transferase (MGMT)-negative CSC ...

journal_title：Journal of neuro-oncology

authors： Beier D,Schriefer B,Brawanski K,Hau P,Weis J,Schulz JB,Beier CP

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:There is an increasing interest in local tumor ablative treatment modalities that induce immunogenic cell death and the generation of antitumor immune responses. METHODS:We report six recurrent glioblastoma patients who were treated with intracavitary thermotherapy after coating the resection cavity wall wi...

journal_title：Journal of neuro-oncology

authors： Grauer O,Jaber M,Hess K,Weckesser M,Schwindt W,Maring S,Wölfer J,Stummer W

更新日期：2019-01-01 00:00:00

abstract：:Compared to classical oncological outcome measures such as time to progression and survival, the importance of cognitive functioning in patients with diffuse infiltrative brain tumors has only recently been recognized. Apart from the relatively low incidence and the invariably fatal outcome of gliomas, the general ass...

journal_title：Journal of neuro-oncology

authors： Klein M,Duffau H,De Witt Hamer PC

更新日期：2012-06-01 00:00:00

abstract：:Stereotactic radiosurgery is a frequently performed procedure for patients with benign intracranial tumors. Benign tumors are good candidates for radiosurgery because they are generally non-invasive, are well visualized by magnetic resonance imaging, and their slow rate of proliferation makes conventional radiation do...

journal_title：Journal of neuro-oncology

authors： Pollock BE

更新日期：2009-05-01 00:00:00

abstract：:Von Hippel-Lindau Disease, a multisystem familial cancer syndrome, is inherited as an autosomal-dominant trait. Common manifestations of the disease are retinal, cerebellar and medullary hemangioblastomas; renal cysts and carcinomas; pancreatic cysts; pheochromocytoma; and papilllary cystadenoma of the epididym. We re...

journal_title：Journal of neuro-oncology

authors： Ertas G,Altundag MB,Ucer AR,Cankal F,Altundag K

更新日期：2005-07-01 00:00:00

abstract：:Intra-cerebrospinal fluid chemotherapy (ICC) is used widely to treat or prevent neoplastic meningitis (NM), although its safety has not been thoroughly assessed. We aimed to analyse the incidence, severity and cause of the adverse reactions provoked by ICC in a cohort of onco-haematological patients. We retrospectivel...

journal_title：Journal of neuro-oncology

authors： Pardo-Moreno J,Fernández C,Arroyo R,Ruiz-Ocaña C,Aláez C,Cuadrado ML

更新日期：2015-11-01 00:00:00

abstract：:The aim of this article is to evaluate and assess the impact of various factors on quality of life (QOL) in adult patients with primary brain tumors seen consecutively in routine neurooncology practice. Two hundred and fifty-seven adult patients, after undergoing surgical intervention and histologically proven primary...

journal_title：Journal of neuro-oncology

authors： Budrukkar A,Jalali R,Dutta D,Sarin R,Devlekar R,Parab S,Kakde A

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Malignant glioma is a lethal brain tumor with a low survival rate and poor prognosis. New strategies are urgently needed to augment the chemotherapeutic effects of temozolomide (TMZ), the standard drug in glioma treatment. Carnosic acid (CA) has been reported to have anticancer, antioxidant and anti-infectiou...

journal_title：Journal of neuro-oncology

authors： Shao N,Mao J,Xue L,Wang R,Zhi F,Lan Q

更新日期：2019-01-01 00:00:00

abstract：:Health-related quality of life (HRQOL) is arguably one of the most important measures in evaluating effectiveness of clinical treatments. At present, there is no disease-specific outcome measure to assess the HRQOL of children, adolescents and young adults with Neurofibromatosis Type 1 (NF1). This study aimed to devel...

journal_title：Journal of neuro-oncology

authors： Nutakki K,Varni JW,Steinbrenner S,Draucker CB,Swigonski NL

更新日期：2017-03-01 00:00:00

abstract：:Adrenomedullin is a vasoactive peptide that is upregulated in higher-grade gliomas and promotes tumor cell proliferation. Since reduced activity of the anti-oncogene PTEN seems to also correlate with higher tumor grade, this suggests an inverse association between PTEN activity and adrenomedullin expression. PC12 pheo...

journal_title：Journal of neuro-oncology

authors： Betchen SA,Musatov S,Roberts J,Pena J,Kaplitt MG

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:The uptake of the boron compound Na2B12H10-SH (BSH) in tumor and normal tissues was investigated in the frame of the EORTC phase I trial 'Postoperative treatment of glioblastoma with BNCT at the Petten Irradiation Facility' (protocol 11961). METHODS AND MATERIALS:The boron concentration in blood, tumor, normal...

journal_title：Journal of neuro-oncology

authors： Hideghéty K,Sauerwein W,Wittig A,Götz C,Paquis P,Grochulla F,Haselsberger K,Wolbers J,Moss R,Huiskamp R,Fankhauser H,de Vries M,Gabel D

更新日期：2003-03-01 00:00:00

abstract：:In earlier studies, we demonstrated that intratumoral infusions of alloreactive cytotoxic T lymphocytes (aCTL), sensitized to the major histocompatibility complex (MHC) antigens of the host, effectively retarded the intracranial growth of Fischer 9L gliosarcoma. We further demonstrated that continuous in vitro exposur...

journal_title：Journal of neuro-oncology

authors： Paul DB,Read SB,Kulprathipanja NV,Gomez GG,Kleinschmidt-DeMasters BK,Schiltz PM,Kruse CA

更新日期：2003-08-01 00:00:00

abstract：:We report a case of association of a brain tumor with multiple colorectal polyposis and offer an analysis of the relevant literature with a view to revising the classification of the syndrome in relation to familial multiple polyposis and Gardner's syndrome. Differences emerged, depending on the brain tumor type, whic...

journal_title：Journal of neuro-oncology

authors： Cervoni L,Celli P,Tarantino R,Fortuna A

更新日期：1995-01-01 00:00:00

abstract：:Ceramide is a physiologic regulator of growth and differentiation in mammalian cells. In this study, the relationship between ceramide and FLICE inhibitory protein (FLIP) in the induction of apoptosis in glioblastoma cell lines was investigated. We found that LN215 cells were slightly more sensitive to Fas-mediated ap...

journal_title：Journal of neuro-oncology

authors： Yoon G,Kim KO,Lee J,Kwon D,Shin JS,Kim SJ,Choi IH

更新日期：2002-11-01 00:00:00

abstract：:The authors report their personal experience with a surgical series of 16 cases of cerebral radiation-induced gliomas, defining diagnostic criteria and surgical and clinical characteristics. There were ten males and six females, with a median age of 45.9 years. Irradiation had initially been given for acute lymphoblas...

journal_title：Journal of neuro-oncology

authors： Salvati M,D'Elia A,Melone GA,Brogna C,Frati A,Raco A,Delfini R

更新日期：2008-09-01 00:00:00

abstract：:Accumulating evidence has supported the role of microRNAs in the initiation and development of malignant tumors. MicroRNA-211 (miR-211), which was reported to involve in diverse physiological activities in several cancers, was investigated for its expression in human glioma and adjacent normal brain tissues, as well a...

journal_title：Journal of neuro-oncology

authors： Zhang J,Lv J,Zhang F,Che H,Liao Q,Huang W,Li S,Li Y

更新日期：2017-07-01 00:00:00

abstract：:Recent developments in the treatment of hematological malignancies, especially with the advent of proteasome inhibitors and immunomodulatory drugs in plasma cell dyscrasias, call for an increased collaboration between hematologists and neurologists. This collaboration involves differentiating chemotherapy-induced peri...

journal_title：Journal of neuro-oncology

authors： Jongen JL,Broijl A,Sonneveld P

更新日期：2015-01-01 00:00:00

abstract：:Despite the accumulating evidences of high chemosensitivity especially in anaplastic oligodendrogliomas with loss of chromosomes 1p and 19q, the optimal management strategy for low-grade tumors using the 1p/19q information remains controversial. We have treated all low-grade oligodendrogliomas by a chemotherapy-preced...

journal_title：Journal of neuro-oncology

authors： Iwadate Y,Matsutani T,Hasegawa Y,Shinozaki N,Higuchi Y,Saeki N

更新日期：2011-05-01 00:00:00

abstract：:Gliomas, the most common malignant primary brain tumors, are universally fatal once they progress from low-grade into high-grade neoplasms. In recent years, we have accumulated unprecedented data about the genetic and epigenetic abnormalities in gliomas; yet, our appreciation of how these deadly tumors arise is still ...

journal_title：Journal of neuro-oncology

authors： Tsankova NM,Canoll P

更新日期：2014-09-01 00:00:00

abstract：:Proneural and mesenchymal are two subtypes of glioblastoma identified by gene expression profiling. In this study, the primary aim was to detect markers to develop a clinically applicable method for distinguishing proneural and mesenchymal glioblastoma. The secondary aims were to investigate the temporospatial dynamic...

journal_title：Journal of neuro-oncology

authors： Murata H,Yoshimoto K,Hatae R,Akagi Y,Mizoguchi M,Hata N,Kuga D,Nakamizo A,Amano T,Sayama T,Iihara K

更新日期：2015-10-01 00:00:00

abstract：:Patients with brain metastasis (BM) from renal cell carcinoma (RCC) are associated with poor prognosis. Between 1990 and 2015, data of consecutive RCC patients with BM were retrospectively analyzed from a urologic oncologic database. The treatment outcome was evaluated by overall survival (OS), which was defined as in...

journal_title：Journal of neuro-oncology

authors： Du Y,Pahernik S,Hadaschik B,Teber D,Duensing S,Jäger D,Hohenfellner M,Grüllich C

更新日期：2016-10-01 00:00:00

abstract：:When a malignant tumor invades the child's cerebellum, the cost of successful treatment is often significant cognitive morbidity. A review of neuropsychological outcome revealed that survivors of childhood medulloblastoma (MB) have long-term deficits in intelligence, memory, language, attention, academic skills, psych...

journal_title：Journal of neuro-oncology

authors： Dennis M,Spiegler BJ,Hetherington CR,Greenberg ML

更新日期：1996-07-01 00:00:00

abstract：:Meningioma is a common intracranial tumor, originating from the meninges of the skull or spinal canal. Most meningiomas are benign tumors, however atypical or anaplastic tumors can be found in 6% of cases. Patients with asymptomatic small benign meningiomas can be followed without therapy, but in symptomatic patients ...

journal_title：Journal of neuro-oncology

authors： Sioka C,Kyritsis AP

更新日期：2009-03-01 00:00:00

abstract：:Carcinomatous meningitis (CM) occurs in less than 10% of cancer patients. Although patients frequently present with a focal complaint, multifocal signs are often found following careful neurological examination. The gold standard for diagnosis remains the demonstration of neoplastic cells in the cerebrospinal fluid. D...

journal_title：Journal of neuro-oncology

authors： McClelland S 3rd,Garcia RE,Monaco SE,Goldman JE,Olson TJ,Kim GH,Petrylak DP,Goodman RR

更新日期：2006-01-01 00:00:00

abstract：:NeuroCogFX is a short yet comprehensive computer-based neuropsychological battery of tests developed to investigate neurological patients for cognitive dysfunction after potentially neurotoxic therapy. NeuroCogFX had been standardized in a group of 242 healthy controls (Fliessbach et al., Fortschr Neurol Psychiatr 74:...

journal_title：Journal of neuro-oncology

authors： Fliessbach K,Rogowski S,Hoppe C,Sabel M,Goeppert M,Helmstaedter C,Calabrese P,Schackert G,Tonn JC,Simon M,Schlegel U

更新日期：2010-12-01 00:00:00