Three-dimensional white matter tractography by diffusion tensor imaging in ischaemic stroke involving the corticospinal tract.

Abstract:

:Diffusion tensor MR imaging (DTI) provides information on diffusion anisotropy, which can be expressed with three-dimensional (3D) white matter tractography. We used 3D white matter tractography to show the corticospinal tract in eight patients with acute or early subacute ischaemic stroke involving the posterior limb of the internal capsule or corona radiata and to assess involvement of the tract. Infarcts and the tract were shown simultaneously, providing information on their spatial relationships. In five of the eight patients, 3D fibre tract maps showed the corticospinal tract in close proximity to the infarct but not to pass through it. All these patients recovered well, with maximum improvement from the lowest score on manual muscle testing (MMT) up to the full score through rehabilitation. In the other three patients the corticospinal tract was shown running through the infarct; reduction in MMT did not necessarily improve favourably or last longer, other than in one patient. As 3D white matter tractography can show spatial relationships between the corticospinal tract and an infarct, it might be helpful in prognosis of gross motor function.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

Kunimatsu A,Aoki S,Masutani Y,Abe O,Mori H,Ohtomo K

doi

10.1007/s00234-003-0974-4

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

532-5

issue

8

eissn

0028-3940

issn

1432-1920

journal_volume

45

pub_type

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