Abstract:
:Our objective was to determine the brain magnetic resonance imaging (MRI) abnormalities in a selected group of patients with mucopolysaccharidosis (MPS) types I and II who had only mild clinical manifestations. We retrospectively assessed MRI brain studies in 18 patients with MPS (type I: 6 and type II: 12). We evaluated abnormal signal intensity in the white matter, widening of the cortical sulci, size of the supratentorial ventricles, dilatation of the perivascular spaces (PVS) and enlargement of the subarachnoid spaces. We observed a broad spectrum of findings, and despite severely abnormal MRI studies, no patients had mental retardation. We also observed that dilated PVS, previously believed to be caused by macroscopic deposition of the mucopolysaccharides, had an appearance similar to cerebrospinal fluid (CSF) in all MRI sequences performed, even in FLAIR and trace diffusion weighted images. Based on our results, we believe that with the exception of white matter abnormalities and brain atrophy, all other findings may be related to abnormal resorption of CSF, and there is no relationship between the imaging and clinical manifestations of the disease.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Matheus MG,Castillo M,Smith JK,Armao D,Towle D,Muenzer Jdoi
10.1007/s00234-004-1215-1subject
Has Abstractpub_date
2004-08-01 00:00:00pages
666-72issue
8eissn
0028-3940issn
1432-1920journal_volume
46pub_type
杂志文章相关文献
NEURORADIOLOGY文献大全abstract::Vacuolar myelopathy (VM) and tract pallor are poorly understood spinal tract abnormalities in patients with the acquired immunodeficiency syndrome (AIDS). We studied the ability of magnetic resonance imaging (MRI) to detect these changes in spinal cord specimens postmortem and whether criteria could be formulated whic...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00588630
更新日期:1995-02-01 00:00:00
abstract::Our purpose was to investigate the potential of an experimental animal coil using a commercial MRI unit to delineate the anatomical structure of the human brain stem. Three formaldehyde-fixed brain-stem specimens were examined by MRI and sectioned perpendicular to their longitudinal axis. The images were compared with...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00596532
更新日期:1996-04-01 00:00:00
abstract::Our purpose was to investigate the role of diffusion imaging (DI) in central nervous system (CNS) infections in pediatric patients. It was anticipated that DI would be more sensitive than conventional MRI in the detection of the infarctive complications of infection, and possibly, in the detection of the infectious pr...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340100625
更新日期:2001-12-01 00:00:00
abstract::Central nervous system involvement is uncommon in Langerhans cell histiocytosis. The suprasellar region is more frequently affected. There have been few reports of involvement of the brain parenchyma shown on CT or MRI. We present a case of involvement of the pons, showing marked contrast enhancement on MRI. ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050559
更新日期:1998-03-01 00:00:00
abstract::An anatomical study of the normal anterior inferior part and the floor of the third ventricle has been made and its radiological appearance shown. Specimens and casts were analyzed and correlated with ventriculograms using watersoluble contrast media. The detailed appearance of the optic recess and sulcus of Monro, wh...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00328385
更新日期:1976-09-21 00:00:00
abstract::Spinal cord infarcts are rare. We report serial MRI studies of a patient with a clinically diagnosed spontaneous spinal cord infarct. The usefulness of gadolinium diethylenetriaminepentaacetic acid-dimeglumine (Gd-DTPA) enhancement is also discussed. Serial MRI with Gd-DTPA is useful to diagnose the spinal cord infarc...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00588149
更新日期:1992-01-01 00:00:00
abstract::CT is the most effective examination technique for studying the evolution of ischemic attacks, but if performed within the first 3 weeks it does not allow prognosis of possible evolution towards necrosis. CBF measurement and vasoreactivity tests under Althesin do allow this prognosis. Thirty patients whose evolution w...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00395259
更新日期:1978-01-01 00:00:00
abstract::We report a primary intraventricular brain abscess in a 13-year-old boy. We discuss possible explanations for this rare occurrence. ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-003-1087-9
更新日期:2003-12-01 00:00:00
abstract::We report a 36-year-old woman whose first MRI after developing symptoms of cervical nerve root irritation was normal. Eight months later, after progression to tetraparesis and demonstration of an extensive contrast-enhancing intramedullary lesion giving high signal on T2-weighted images, the diagnosis of lymphoblastic...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340100701
更新日期:2002-03-01 00:00:00
abstract::Gadolinium based MRI contrast agents are considered very safe due to their well known pharmacologic properties and elimination mechanisms. In this paper, we present a unique case in whom transient enhancement of CSF with contrast is seen. Severe renal failure is demonstrated to be responsible for this finding. The dia...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340100606
更新日期:2001-11-01 00:00:00
abstract::We reviewed the imaging of four pathologically proven calvarial eosinophil granulomas. The diameter of the lesions ranged from 13 to 40 mm; three were biconvex, but the other had a collar-stud appearance. Two lesions were in the frontal and two in the parietal bone. On bone-window CT, a bevelled edge was seen in three...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050831
更新日期:1999-10-01 00:00:00
abstract:INTRODUCTION:Novel postprocessing techniques have enabled accurate quantification of intracranial carotid atherosclerotic disease on CT Angiography (CTA). Our purpose was to estimate the prevalence of intracranial carotid artery disease, i.e., stenosis and calcium, on CTA in patients with recent neurological symptoms. ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-012-1097-6
更新日期:2013-02-01 00:00:00
abstract::The rate of side effects, the results of EMG, EEG and CSF changes after radiculography, the rates of late leptomeningeal changes and the details of the hyperosmolality following the ionic contrast media are recorded and discussed. In conclusion rules are presented for the choice of contrast medium and the examination ...
journal_title:Neuroradiology
pub_type: 临床试验,杂志文章
doi:10.1007/BF00345269
更新日期:1978-11-24 00:00:00
abstract:INTRODUCTION:This study aims to evaluate the existence of anatomic abnormalities in the skull base that could contribute to the origin of primary spontaneous cerebrospinal fluid leaks (PSL). METHODS:Twenty PSL patients were compared with 20 healthy individuals. The following features were measured through an analysis ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-011-0901-z
更新日期:2012-05-01 00:00:00
abstract::A patient presented with the clinical features of a brain stem infarct. MRI confirmed changes of infarction but also revealed an unusual lesion in the left cerebellopontine angle cistern. The evolution of this lesion on MRI, together with angiographic changes, indicated a dissecting aneurysm of the left anterior infer...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340000324
更新日期:2000-07-01 00:00:00
abstract::It is possible to underestimate the grade of nonenhancing cerebral tumours on conventional contrast-enhanced MRI or CT. Differentiation of high- and low-grade gliomas by measurement of the brain-blood partition coefficient lambda (T lambda) with Xe-enhanced CT (XeCT) has been reported. We assessed the practical applic...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050481
更新日期:1997-09-01 00:00:00
abstract:INTRODUCTION:Type 2 diabetes (DM2) is associated with cognitive decline, but the pathogenesis of this important complication remains unclear. We investigated whether abnormalities in neuronal metabolism or membrane integrity in normal appearing cerebral white matter are associated with cognitive impairment in patients ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-009-0598-4
更新日期:2010-02-01 00:00:00
abstract::Local intra-arterial fibrinolysis (LIF) is considered to support spontaneous recanalisation, which does not usually occur fast enough to prevent an infarct. Therefore, LIF may, at least theoretically, be especially useful in occlusions with large thromboembolic masses. We report our experience of LIF with urokinase in...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050375
更新日期:1997-02-01 00:00:00
abstract::We assessed reproducible definition of two standardized co-ordinate systems for intersubject analysis of brain images. The baselines in the two co-ordinate systems were a modification of the canthomeatal (mCM) line and the anterior-posterior commissural (AC-PC) line. Axial spin-echo MR images of four subjects at 1.5T ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00593507
更新日期:1994-10-01 00:00:00
abstract::Spinal intradural extramedullary cavernous hemangiomas are very rare. Mixed intensities on T1- andT2-weighted images due to repeated hemorrhages and poor to absent contrast-enhancement are the most common imaging features of the disease allowing accurate differentiation from the far more frequent meningiomas and schwa...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-018-2073-6
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:Not uncommonly, differentiating multiple sclerosis (MS) from ischemic cerebral vascular disease is difficult based on conventional magnetic resonance imaging (MRI). We aim to determine whether preferential occult injury in the normal-appearing corpus callosum (NACC) is more severe in patients with MS than ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-009-0535-6
更新日期:2009-09-01 00:00:00
abstract::Nine angiomatous malformations situated on the outer surface of the dura and one situated in the pelvis, from which draining veins pierced the dura and joined the coronal venous plexus are described. The clinical manifestations and myelographic appearances are similar to those of the majority of intradural angiomatous...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00344211
更新日期:1977-06-27 00:00:00
abstract::Tumors of the pediatric facial skeleton represent a major challenge in clinical practice because they can lead to functional impairment, facial deformation, and long-term disfigurement. Their treatment often requires a multidisciplinary approach, and radiologists play a pivotal role in the diagnosis and management of ...
journal_title:Neuroradiology
pub_type: 杂志文章,评审
doi:10.1007/s00234-017-1798-y
更新日期:2017-04-01 00:00:00
abstract::We report three adenomatous middle-ear tumours, an adenoma, an adenocarcinoma and a semimalignant adenomatous tumour, with special attention to CT and MRI findings. In all cases we found small intratympanic masses in which the ossicles were embedded. All showed contrast enhancement and similar signal intensity as brai...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340000477
更新日期:2001-01-01 00:00:00
abstract::Diffusion tensor MR imaging (DTI) provides information on diffusion anisotropy, which can be expressed with three-dimensional (3D) white matter tractography. We used 3D white matter tractography to show the corticospinal tract in eight patients with acute or early subacute ischaemic stroke involving the posterior limb...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-003-0974-4
更新日期:2003-08-01 00:00:00
abstract::Chordoma is a rare cartilaginous tumor, for which bleeding presentation is unusual. We report a case of rare hemorrhaged clival chordoma, which was diagnosed correctly by magnetic resonance imaging. A 32-year-old man presented with nasal bleeding. The tumor was totally removed via a trans-sphenoidal approach, from whi...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-005-1367-7
更新日期:2005-05-01 00:00:00
abstract::We studied serial MRI appearances of transneuronal degeneration in the inferior olives, retrospectively analysing follow-up images of five patients, three with head injury and two with brain stem haemorrhage. We performed 13 MRI studies 4 days to 2 years 7 months after the accident. All but one of the patients exhibit...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050695
更新日期:1999-01-01 00:00:00
abstract::Our aim was to determine whether MRI reliably shows pathology in patients with active otosclerosis (otospongiosis). We studied five patients with clinical and audiometric signs of this disorder and positive findings on high-resolution CT and tympanocochlear scintigraphy. Contrast enhancement of otospongiotic lesions w...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050445
更新日期:1997-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to describe imaging markers of decision-making under uncertain conditions in normal individuals, in order to provide baseline activity to compare to impaired decision-making in pathological states. METHODS:In this cross-sectional study, 19 healthy subjects ages 18-35 completed a novel...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-017-1949-1
更新日期:2018-01-01 00:00:00
abstract::A new technique for surgical construction of experimental lateral saccular aneurysms on the common carotid artery of swine is described. It involves end-to-side suturing of an isolated segment of vein to an artery. During a short period of parent artery clamping, an elliptical arteriotomy is fashioned through the open...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00593518
更新日期:1994-10-01 00:00:00