Primary CNS lymphoma in the spinal cord: clinical manifestations may precede MRI detectability.

Abstract:

:We report a 36-year-old woman whose first MRI after developing symptoms of cervical nerve root irritation was normal. Eight months later, after progression to tetraparesis and demonstration of an extensive contrast-enhancing intramedullary lesion giving high signal on T2-weighted images, the diagnosis of lymphoblastic non-Hodgkin's lymphoma was made by biopsy. The lesion responded for a short time to corticosteroid medication, but later rapidly extended to the epidural soft tissues, probably due to a cerebrospinal fluid fistula. Despite radio-and chemotherapy, the patient survived only 7 months from histological diagnosis and 15 months from the onset of symptoms.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

Herrlinger U,Weller M,Küker W

doi

10.1007/s002340100701

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

239-44

issue

3

eissn

0028-3940

issn

1432-1920

journal_volume

44

pub_type

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