Differentiation of residual/recurrent gliomas from postradiation necrosis with arterial spin labeling and diffusion tensor magnetic resonance imaging-derived metrics.

Abstract:

PURPOSE:The aim of this study is to differentiate recurrent/residual gliomas from postradiation changes using arterial spin labeling (ASL) perfusion and diffusion tensor imaging (DTI)-derived metrics. METHODS:Prospective study was conducted upon 42 patients with high-grade gliomas after radiotherapy only or prior to other therapies that underwent routine MR imaging, ASL, and DTI. The tumor blood flow (TBF), fractional anisotropy (FA), and mean diffusivity (MD) of the enhanced lesion and related edema were calculated. The lesion was categorized as recurrence/residual or postradiation changes. RESULTS:There was significant differences between residual/recurrent gliomas and postradiation changes of TBF (P = 0.001), FA (P = 0.001 and 0.04), and MD (P = 0.001) of enhanced lesion and related edema respectively. The area under the curve (AUC) of TBF of enhanced lesion and related edema used to differentiate residual/recurrent gliomas from postradiation changes were 0.95 and 0.93 and of MD were 0.95 and 0.81 and of FA were 0.81 and 0.695, respectively. Combined ASL and DTI metrics of the enhanced lesion revealed AUC of 0.98, accuracy of 95%, sensitivity of 93.8%, specificity of 95.8%, positive predictive value (PPV) of 93.8%, and negative predictive value (NPV) of 95.8%. Combined metrics of ASL and DTI of related edema revealed AUC of 0.97, accuracy of 92.5%, sensitivity of 93.8%, specificity of 91.7%, PPV of 88.2%, and NPV of 95.7. CONCLUSION:Combined ASL and DTI metrics of enhanced lesion and related edema are valuable noninvasive tools in differentiating residual/recurrent gliomas from postradiation changes.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

Razek AAKA,El-Serougy L,Abdelsalam M,Gaballa G,Talaat M

doi

10.1007/s00234-017-1955-3

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

169-177

issue

2

eissn

0028-3940

issn

1432-1920

pii

10.1007/s00234-017-1955-3

journal_volume

60

pub_type

杂志文章
  • Cervical spinal canal narrowing in idiopathic syringomyelia.

    abstract:INTRODUCTION:The cervical spine in Chiari I patient with syringomyelia has significantly different anteroposterior diameters than it does in Chiari I patients without syringomyelia. We tested the hypothesis that patients with idiopathic syringomyelia (IS) also have abnormal cervical spinal canal diameters. The finding ...

    journal_title:Neuroradiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00234-016-1701-2

    authors: Struck AF,Carr CM,Shah V,Hesselink JR,Haughton VM

    更新日期:2016-08-01 00:00:00

  • Accidental introduction of contrast medium into the cervical spinal cord. A case report.

    abstract::The density of metrizamide injected accidentally into the spinal cord during cervical CT myelography was measured with CT scanning and compared with a series of dilutions of metrizamide scanned with a special phantom. The test suggests that the metrizamide is diluted rapidly in the spinal canal, and in an accidental i...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00342522

    authors: Servo A,Laasonen EM

    更新日期:1985-01-01 00:00:00

  • Axial diffusivity is increased in the degenerating superior cerebellar peduncles of Friedreich's ataxia.

    abstract:INTRODUCTION:Decreased fractional anisotropy (FA) demonstrated by diffusion tensor MR imaging (DTI) in areas of white matter (WM) damage is generally associated with increase of radial diffusivity, while axial diffusivity is reported to be decreased, unchanged, or increased. Aiming to better define the type of axial di...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-010-0807-1

    authors: Della Nave R,Ginestroni A,Diciotti S,Salvatore E,Soricelli A,Mascalchi M

    更新日期:2011-05-01 00:00:00

  • Cervical intervertebral foramen narrowing and myelographic nerve root sleeve deformities.

    abstract::Intervertebral foramen narrowing on plain radiographs of the cervical spine was graded from 0 (normal) to 3 according to its severity; myelographic nerve root sleeve deformity was graded from 1 to 3 in 99 consecutive patients with cervical radiculopathy. We thus examined 1118 foramina and root sleeves. Plain radiograp...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588403

    authors: Pyhtinen J,Laitinen J

    更新日期:1993-01-01 00:00:00

  • Characterization and therapy monitoring of head and neck carcinomas using diffusion-imaging-based intravoxel incoherent motion parameters-preliminary results.

    abstract:INTRODUCTION:Using the intravoxel incoherent motion (IVIM) model, diffusion-related coefficient (D) and perfusion-related parameter (f) can be measured. Here, we used IVIM imaging to characterize squamous cell carcinomas of head and neck (HNSCC) and evaluated its application in follow-up after nonsurgical organ preserv...

    journal_title:Neuroradiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00234-013-1154-9

    authors: Hauser T,Essig M,Jensen A,Gerigk L,Laun FB,Münter M,Simon D,Stieltjes B

    更新日期:2013-05-01 00:00:00

  • Stability of ischemic core volume during the initial hours of acute large vessel ischemic stroke in a subgroup of mechanically revascularized patients.

    abstract:INTRODUCTION:This study aimed to relate growth of the infarct core with time to recanalization in patients receiving mechanical recanalization in whom the time of recanalization is known. METHODS:We analyzed data from patients with anterior circulation acute ischemic stroke who underwent mechanical recanalization. Dem...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-014-1329-z

    authors: Finitsis S,Kemmling A,Havemeister S,Thomalla G,Fiehler J,Brekenfeld C

    更新日期:2014-04-01 00:00:00

  • CT findings of bilateral congenital absence of the long process of the incus.

    abstract::Bilateral conductive deafness due to congenital absence of the long process of the incus (CALPI) is rare. The authors present the case of a patient with bilateral CALPI. To the best of our knowledge, this is the first reported case preoperatively diagnosed as bilateral CALPI by computed tomography. Multislice computed...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-004-1200-8

    authors: Watanabe A,Miyashima H,Kobashi T,Take K

    更新日期:2004-10-01 00:00:00

  • Transcriptomic analysis of the harvested endothelial cells in a swine model of mechanical thrombectomy.

    abstract:PURPOSE:In mechanical thrombectomy (MT) for ischemic stroke, endothelial cells (ECs) from intracranial blood vessels adhere to the stent retriever device and can be harvested. However, understanding the molecular biology and the role of the endothelium in different pathological conditions remains insufficient. The purp...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-018-2033-1

    authors: Jaff N,Grankvist R,Muhl L,Chireh A,Sandell M,Jonsson S,Arnberg F,Eriksson U,Holmin S

    更新日期:2018-07-01 00:00:00

  • Posterior fossa epidural hematoma. A report of three cases diagnosed with computed tomography.

    abstract::CT demonstrated posterior fossa epidural hematoma in three patients with head trauma in whom this diagnosis was not clinically apparent. No patient was in stupor or coma and no patient experienced a lucid interval. Only one patient had signs referable to the posterior fossa. Two patients had occipital skull fracture d...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:

    authors: Kushner MJ,Luken MG 3rd

    更新日期:1983-01-01 00:00:00

  • Multiplanar reconstructed CT images increased depiction of intracranial hemorrhages in pediatric head trauma.

    abstract:INTRODUCTION:The benefits of multiplanar reconstructed images (MPR) of unenhanced axial head computed tomography (CT) data have not been established in trauma patients younger than 3 years old, a population in which a reliable history and physical examination may be most difficult. We retrospectively evaluated unenhanc...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-015-1584-7

    authors: Langford S,Panigrahy A,Narayanan S,Hwang M,Fitz C,Flom L,Lee VK,Zuccoli G

    更新日期:2015-12-01 00:00:00

  • Fracture of the anterior arch of the atlas associated with a congenital cleft of the posterior arch. Demonstration by CT.

    abstract::A case of a vertical fracture of the anterior arch of the atlas associated with a congenital cleft of the posterior arch of the same vertebra is reported. Such an association has not previously been described in the literature. X-Ray computed tomography is an excellent exam for visualizing this region and for easily d...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00404112

    authors: Le Minor JM,Rosset P,Favard L,Burdin P

    更新日期:1988-01-01 00:00:00

  • Stent-assisted angioplasty for intracranial atherosclerosis.

    abstract::We report on two patients with intracranial atherosclerosis of the carotid artery or vertebral artery treated with stent-assisted angioplasty. Both patients have severe intracranial atherosclerosis (>70%) with refractory symptoms despite optimal medical treatment. In both patients, a coronary balloon-expandable stent ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-002-0794-y

    authors: Nakahara T,Sakamoto S,Hamasaki O,Sakoda K

    更新日期:2002-08-01 00:00:00

  • Adding brain volume measures into response criteria in multiple sclerosis: the Río-4 score.

    abstract:PURPOSE:Brain volume changes (BVC) on therapy in MS are being considered as predictor for treatment response at an individual level. We ought to assess whether adding BVC as a factor to monitor interferon-beta response improves the predictive ability of the (no) evidence of disease activity (EDA-3) and Río score (RS-3)...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-020-02604-8

    authors: Pérez-Miralles FC,Río J,Pareto D,Vidal-Jordana À,Auger C,Arrambide G,Castilló J,Tintoré M,Rovira À,Montalban X,Sastre-Garriga J

    更新日期:2020-11-25 00:00:00

  • [Comparison of CT, scintigraphy, and angiography in the topographic and pathological diagnosis of 300 supratentorial tumors (author's transl)].

    abstract::The results of CT, scintigraphy (CSS), and angiography in 300 supratentorial cerebral tumors were compared with regard to the topographic and pathological diagnosis proposed in the initial reports. CT elucidated the topography in 98% of the cases and the pathology in variable percentages, depending on the type of tumo...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00395344

    authors: Metzger J,Gardeur D,Nachanakian A,Millard JC

    更新日期:1978-01-01 00:00:00

  • Lower fractional anisotropy at the anterior body of the normal-appearing corpus callosum in multiple sclerosis versus symptomatic carotid occlusion.

    abstract:INTRODUCTION:Not uncommonly, differentiating multiple sclerosis (MS) from ischemic cerebral vascular disease is difficult based on conventional magnetic resonance imaging (MRI). We aim to determine whether preferential occult injury in the normal-appearing corpus callosum (NACC) is more severe in patients with MS than ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-009-0535-6

    authors: Lou X,Jiang W,Ma L,Ma N,Cai Y,Huang D,Wong EH

    更新日期:2009-09-01 00:00:00

  • Postpartum cerebral angiopathy: atypical features and treatment with intracranial balloon angioplasty.

    abstract::Postpartum cerebral angiopathy (PCA) is an uncommon cause of ischemic and hemorrhagic stroke in young women. It is usually clinically benign and not relapsing. We describe a patient with nonhemorrhagic PCA who had an atypical progressive neurological deficit from bilateral hemisphere watershed ischemia despite treatme...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-003-1129-3

    authors: Song JK,Fisher S,Seifert TD,Cacayorin ED,Alexandrov AV,Malkoff MD,Grotta JC,Campbell MS

    更新日期:2004-12-01 00:00:00

  • Horizontal stent placement plus coiling in a broad-based basilar-tip aneurysm: an alternative to the Y-stent technique.

    abstract:INTRODUCTION:Basilar tip aneurysms are the most frequent type of aneurysm in the posterior circulation. Specifically, if wide-necked, they remain a significant therapeutic challenge. On the endovascular side, stents may help to overcome many of these technical challenges. However, if both P1 segments encroach into the ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-006-0128-6

    authors: Wanke I,Gizewski E,Forsting M

    更新日期:2006-11-01 00:00:00

  • Global and focal cerebral perfusion after aneurysmal subarachnoid hemorrhage in relation with delayed cerebral ischemia.

    abstract:INTRODUCTION:The pathogenesis of delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) is unclear. We assessed whether DCI relates to focal or global cerebral perfusion on admission and on follow-up imaging. MATERIALS AND METHODS:Twenty-seven SAH patients underwent computed tomography (CT) perfusion (CTP...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-008-0416-4

    authors: Rijsdijk M,van der Schaaf IC,Velthuis BK,Wermer MJ,Rinkel GJ

    更新日期:2008-09-01 00:00:00

  • Diffuse dural enhancement in cavernous sinus dural arteriovenous fistula.

    abstract::We describe unusually extensive contrast enhancement of the dura mater on MRI in a case of dural arteriovenous fistula of the cavernous sinus. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-002-0920-x

    authors: Rucker JC,Newman NJ

    更新日期:2003-02-01 00:00:00

  • Unilateral delayed opercularization in a case of Sotos' syndrome (Cerebral Gigantism).

    abstract::A case of Sotos' syndrome (cerebral gigantism) is described. Pneumencephalography, performed at the age of 15 days, revealed abnormal separation of the opercula on the right. By comparing the contours with developmental anatomical features of this area it agreed with a foetal development of 24 weeks gestational age. B...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00346862

    authors: Barth PG,Vlasveld L,Valk J

    更新日期:1980-08-01 00:00:00

  • Normal age-related signal change in the laryngeal cartilages.

    abstract::MRI may be used for detecting cartilage invasion in patients with laryngeal carcinoma. However, the normal laryngeal ossification pattern has not been studied. Our purpose was to examine the normal age-related signal patterns in the cricoid, thyroid and arytenoid cartilages on T1-weighted images. Signal in the cartila...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-003-1153-3

    authors: Fatterpekar GM,Mukherji SK,Rajgopalan P,Lin Y,Castillo M

    更新日期:2004-08-01 00:00:00

  • CT and MRI of ruptured intracranial dermoids.

    abstract::Two patients with ruptured intracranial dermoids, examined with both CT and MRI are reported. Clinical presentation was transient cerebral ischemia in one patient and acute meningeal signs in the other. CT scan showed typical fat density of the tumor and the subarachnoid space. On MRI both the tumor and the subarachno...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588254

    authors: Wilms G,Casselman J,Demaerel P,Plets C,De Haene I,Baert AL

    更新日期:1991-01-01 00:00:00

  • Endovascular treatment of intracranial aneurysms with the p64 flow diverter stent: mid-term results in 35 patients with 41 intracranial aneurysms.

    abstract:INTRODUCTION:The p64 flow diverter (FD) device is a fully resheathable and detachable stent dedicated for endovascular treatment (EVT) of intracranial aneurysms (IAs). We report our mid-term experience with this device. METHODS:Between January 2015 and February 2016, we retrospectively identified, in our prospectively...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-017-1786-2

    authors: Morais R,Mine B,Bruyère PJ,Naeije G,Lubicz B

    更新日期:2017-03-01 00:00:00

  • Results of a double blind study of three contrast media and technic for lumbosacral radiculography.

    abstract::The rate of side effects, the results of EMG, EEG and CSF changes after radiculography, the rates of late leptomeningeal changes and the details of the hyperosmolality following the ionic contrast media are recorded and discussed. In conclusion rules are presented for the choice of contrast medium and the examination ...

    journal_title:Neuroradiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF00345269

    authors: Hammer B

    更新日期:1978-11-24 00:00:00

  • Morphology of cerebral lesions in children with congenital hemiplegia. A study with computed tomography.

    abstract::This study has analysed the results of CT scans of the brains in children with congenital hemiplegia. The material consists of 111 out of a total of 151 children with this cerebral palsy syndrome in a population-based series. We have classified the morphological findings in five groups. The groups are designed to refl...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00589107

    authors: Wiklund LM,Uvebrant P,Flodmark O

    更新日期:1990-01-01 00:00:00

  • MRI-derived measurements of fibrous-cap and lipid-core thickness: the potential for identifying vulnerable carotid plaques in vivo.

    abstract::Vulnerable plaques have thin fibrous caps overlying large necrotic lipid cores. Recent studies have shown that high-resolution MR imaging can identify these components. We set out to determine whether in vivo high-resolution MRI could quantify this aspect of the vulnerable plaque. Forty consecutive patients scheduled ...

    journal_title:Neuroradiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00234-004-1247-6

    authors: Trivedi RA,U-King-Im JM,Graves MJ,Horsley J,Goddard M,Kirkpatrick PJ,Gillard JH

    更新日期:2004-09-01 00:00:00

  • Spinal tract pathology in AIDS: postmortem MRI correlation with neuropathology.

    abstract::Vacuolar myelopathy (VM) and tract pallor are poorly understood spinal tract abnormalities in patients with the acquired immunodeficiency syndrome (AIDS). We studied the ability of magnetic resonance imaging (MRI) to detect these changes in spinal cord specimens postmortem and whether criteria could be formulated whic...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588630

    authors: Santosh CG,Bell JE,Best JJ

    更新日期:1995-02-01 00:00:00

  • Diagnostic imaging in the management of patients with possible cerebral venous thrombosis: a cost-effectiveness analysis.

    abstract:PURPOSE:Imaging is crucial for management of patients with possible cerebral venous thrombosis (CVT). To evaluate the cost-effectiveness of different noninvasive imaging strategies in patients with possible CVT. METHODS:A decision model based on Markov simulations estimated lifetime costs and quality-adjusted life yea...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-019-02252-7

    authors: Hedderich DM,Ferro JM,Kunz WG

    更新日期:2019-10-01 00:00:00

  • MRA versus digital subtraction angiography in acute subarachnoid haemorrhage: a blinded multireader study of prospectively recruited patients.

    abstract::We performed a blinded multireader study comparing MR angiography (MRA) with digital subtraction angiography (DSA) in 34 prospectively recruited patients who presented with acute subarachnoid haemorrhage (SAH). Two observers independently reviewed the MRA and DSA studies some months after clinical presentation. Presen...

    journal_title:Neuroradiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s002340050892

    authors: Jäger HR,Mansmann U,Hausmann O,Partzsch U,Moseley IF,Taylor WJ

    更新日期:2000-05-01 00:00:00

  • Early and midterm results of complex cerebral aneurysms treated with Silk stent.

    abstract:INTRODUCTION:Endovascular treatment of intracranial aneurysms has been an effective treatment option. In this paper, we report our experience with the Silk stent (SS) for endovascular treatment of complex intracranial aneurysms and present periprocedural events, immediate results, delayed complications, and imaging and...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-012-1051-7

    authors: Velioglu M,Kizilkilic O,Selcuk H,Kocak B,Tureci E,Islak C,Kocer N

    更新日期:2012-12-01 00:00:00