Abstract:
:It is possible to underestimate the grade of nonenhancing cerebral tumours on conventional contrast-enhanced MRI or CT. Differentiation of high- and low-grade gliomas by measurement of the brain-blood partition coefficient lambda (T lambda) with Xe-enhanced CT (XeCT) has been reported. We assessed the practical applications of XeCT in suspected low-grade astrocytomas. We examined 15 patients with tumours which showed no contrast enhancement on conventional MRI and CT, using XeCT. Tumour blood flow (TBF) and T lambda were calculated. Fourteen patients underwent surgery, one patient had a biopsy. We recognized three histological groups. While T lambda differed significantly between them, TBF did not. Group 1 contained grade II-III astrocytomas and T lambda was 0.77; group 2 contained grade I-II astrocytomas with T lambda 1.14, and group 3 four oligodendrogliomas in which a T lambda of 1.50 was found.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Nasel C,Rössler K,Heimberger K,Görzer H,Lassmann H,Schindler Edoi
10.1007/s002340050481subject
Has Abstractpub_date
1997-09-01 00:00:00pages
627-32issue
9eissn
0028-3940issn
1432-1920journal_volume
39pub_type
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